Showing BioInteractions for Omega-3 fatty acids (DB11133)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 3
Enzyme Mediated Interactions 2

	Interacting Group	Interacting Drugs
	Omega-3 fatty acids is a Peroxisome proliferator-activated receptor gamma ligand
1	Peroxisome proliferator-activated receptor gamma agonists	Aleglitazar, Amiodarone, Balsalazide, Bezafibrate, Darglitazone, Flufenamic acid, Glipizide, Icosapent, Isoflavone, Mesalazine, Mitiglinide, Nateglinide, Pioglitazone, Repaglinide, Rosiglitazone, Sulfasalazine, Troglitazone
2	Peroxisome proliferator-activated receptor gamma partial agonists	AMG-131, Telmisartan
3	Peroxisome proliferator-activated receptor gamma activators	Cannabidiol, Dexibuprofen, Ibuprofen, Indomethacin, Lobeglitazone
4	Peroxisome proliferator-activated receptor gamma ligands	Capric acid, Doconexent, Oleic Acid
5	Peroxisome proliferator-activated receptor gamma modulators	Clofazimine

	Interacting Group	Interacting Drugs
	Omega-3 fatty acids is a Peroxisome proliferator-activated receptor alpha activator
1	Peroxisome proliferator-activated receptor alpha agonists	Aleglitazar, Amiodarone, Bezafibrate, Cardarine, Clofibrate, Fenofibrate, Fenofibric acid, Gemfibrozil, Indomethacin, Isoflavone, Myrrh
2	Peroxisome proliferator-activated receptor alpha activators	Fenoprofen, Flufenamic acid, Ibuprofen, Leukotriene B4, Prasterone, Soybean oil
3	Peroxisome proliferator-activated receptor alpha ligands	Doconexent

	Interacting Group	Interacting Drugs
	Omega-3 fatty acids is a Sterol regulatory element-binding protein 1 inhibitor
1	Sterol regulatory element-binding protein 1 inhibitors	Doconexent, Omega-3-acid ethyl esters

	Interacting Group	Interacting Drugs
	Omega-3 fatty acids is a Prostaglandin G/H synthase 2 substrate
1	Prostaglandin G/H synthase 2 inhibitors	Aceclofenac, Acetaminophen, Acetylsalicylic acid, Aminosalicylic acid, Antipyrine, Antrafenine, Balsalazide, Bromfenac, Bufexamac, Cannabidiol, Capsaicin, Carprofen, Celecoxib, Chlorphenesin, Choline magnesium trisalicylate, Cimicoxib, Cisplatin, Clodronic acid, Dexibuprofen, Dexketoprofen, Diclofenac, Diflunisal, Drospirenone, Droxicam, Etodolac, Etoricoxib, Fenoprofen, Fish oil, Flurbiprofen, Ginseng, Ibuprofen, Icosapent, Indomethacin, Ketoprofen, Ketorolac, Lornoxicam, Lumiracoxib, Magnesium salicylate, Meclofenamic acid, Medical Cannabis, Mefenamic acid, Meloxicam, Mesalazine, Morniflumate, Nabiximols, Nabumetone, Naproxen, Nepafenac, Niflumic acid, Nimesulide, Oxaprozin, Parecoxib, Phenylbutazone, Piroxicam, Pomalidomide, Resveratrol, Rofecoxib, Salicylic acid, Salsalate, Seliciclib, Sulfasalazine, Sulindac, Suprofen, Talniflumate, Tenoxicam, Tiaprofenic acid, Tolmetin, Triamcinolone, Trolamine salicylate, Valdecoxib
2	Prostaglandin G/H synthase 2 negative modulators	Lenalidomide
3	Prostaglandin G/H synthase 2 antagonists	Acemetacin, Alclofenac, Dexketoprofen, Glycol salicylate, Loxoprofen, Menthyl salicylate, Phenyl salicylate, Propacetamol, Talniflumate, Thalidomide, Tolfenamic acid
4	Prostaglandin G/H synthase 2 substrates	Dapsone, Etoposide, Omega-6 fatty acids, Thalidomide
5	Prostaglandin G/H synthase 2 inducers	Aldesleukin, Bryostatin 1, Bumetanide, Desmopressin, Drospirenone, Nonoxynol-9, Prasterone sulfate, Risedronic acid, Sapropterin, Sar9, Met (O2)11-Substance P, Semaxanib, Tafluprost

	Interacting Group	Interacting Drugs
	Omega-3 fatty acids is a Arachidonate 5-lipoxygenase substrate
1	Arachidonate 5-lipoxygenase inhibitors	Aminosalicylic acid, Balsalazide, Cannabidiol, Diacerein, Diethylcarbamazine, Fostamatinib, Hyperforin, Masoprocol, Meclofenamic acid, Medical Cannabis, Mesalazine, Minocycline, Morniflumate, Nabiximols, Rhein, Sulfasalazine, Zileuton
2	Arachidonate 5-lipoxygenase substrates	Omega-6 fatty acids
3	Arachidonate 5-lipoxygenase antagonists	Morniflumate
4	Arachidonate 5-lipoxygenase potentiators	Diclofenac