Diabetic Neuropathies

Also known as: Diabetic neuropathy / Neuropathy, Diabetic

DrugDrug NameDrug Description
DB00321AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
DB00215CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
DB01151DesipramineA tricyclic antidepressant used in the treatment of depression.
DB00343DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
DrugDrug NameTargetType
DB00321AmitriptylineSodium-dependent serotonin transportertarget
DB00321AmitriptylineSodium-dependent noradrenaline transportertarget
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
DB00321AmitriptylineAlpha-2A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 1A2enzyme
DB00321AmitriptylineCytochrome P450 2C19enzyme
DB00321AmitriptylineCytochrome P450 2D6enzyme
DB00321AmitriptylineSerum albumincarrier
DB00321AmitriptylineAlpha-1-acid glycoprotein 1carrier
DB00321AmitriptylineHistamine H1 receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 2Atarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Atarget
DB00321AmitriptylineAlpha-1A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 3A4enzyme
DB00321AmitriptylineCytochrome P450 3A5enzyme
DB00321AmitriptylinePotassium voltage-gated channel subfamily A member 1target
DB00321AmitriptylineAlpha-1D adrenergic receptortarget
DB00321AmitriptylineDelta-type opioid receptortarget
DB00321AmitriptylineKappa-type opioid receptortarget
DB00321AmitriptylineHigh affinity nerve growth factor receptortarget
DB00321AmitriptylineBDNF/NT-3 growth factors receptortarget
DB00321AmitriptylineCytochrome P450 2C9enzyme
DB00321AmitriptylineCytochrome P450 2B6enzyme
DB00321AmitriptylineCytochrome P450 2C8enzyme
DB00321AmitriptylineHistamine H2 receptortarget
DB00321AmitriptylineHistamine H4 receptortarget
DB00321AmitriptylineSigma non-opioid intracellular receptor 1target
DB00321Amitriptyline5-hydroxytryptamine receptor 2Ctarget
DB00321AmitriptylineAlpha-1B adrenergic receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 7target
DB00321Amitriptyline5-hydroxytryptamine receptor 1Dtarget
DB00321AmitriptylineMu-type opioid receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Btarget
DB00321Amitriptyline5-hydroxytryptamine receptor 6target
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
DB00321AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
DB00321Amitriptyline5-hydroxytryptamine receptor 1Ctarget
DB00321AmitriptylineMuscarinic acetylcholine receptortarget
DB00321AmitriptylineHERG human cardiac K+ channeltarget
DB00321AmitriptylineP-glycoprotein 1transporter
DB00321AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
DB00215CitalopramSodium-dependent serotonin transportertarget
DB00215CitalopramCytochrome P450 2C19enzyme
DB00215CitalopramCytochrome P450 2D6enzyme
DB00215CitalopramCytochrome P450 3A4enzyme
DB00215CitalopramP-glycoprotein 1transporter
DB00215CitalopramCytochrome P450 1A2enzyme
DB00215CitalopramHistamine H1 receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineP-glycoprotein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineDopamine D2 receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemP-glycoprotein 1transporter
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemSerum albumincarrier
DB00343DiltiazemAlpha-1-acid glycoprotein 1carrier
DB00343DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DrugDrug NamePhaseStatusCount
DB00318Codeine1Completed1
DB06700Desvenlafaxine1Completed1
DB00281Lidocaine1Not Yet Recruiting1
DB00715Paroxetine1Completed1
DB00230Pregabalin1Completed1
DB05066Ibudilast1 / 2Completed1
DB09061Cannabidiol2Recruiting1
DB06774Capsaicin2Completed1
DB06774Capsaicin2Terminated1
DB12338Carisbamate2Completed1
DB12830Cebranopadol2Completed1
DB14256Centella asiatica2Completed1
DB00575Clonidine2Completed2
DB00514Dextromethorphan2Completed1
DB00476Duloxetine2Completed1
DB12102Fulranumab2Terminated1
DB04922Gabapentin enacarbil2Completed1
DB08872Gabapentin enacarbil2Completed1
DB08872Gabapentin enacarbil2Terminated1
DB00028Immune globulin human2Recruiting1
DB06296Indantadol2Completed1
DB06218Lacosamide2Recruiting1
DB14009Medical Cannabis2Completed1
DB00670Pirenzepine2Recruiting1
DB00230Pregabalin2Completed3
DB05533QR-3332Completed1
DB00234Reboxetine2Terminated1
DB11829Ruboxistaurin2Completed1
DB09153Sodium chloride2Recruiting1
DB12527Sofinicline2Completed1
DB06204Tapentadol2Completed1
DB00273Topiramate2Completed1
DB06218Lacosamide2 / 3Completed2
DB08883Perampanel2 / 3Completed1
DB00316Acetaminophen3Completed1
DB00102Becaplermin3Terminated1
DB11748Benfotiamine3Unknown Status1
DB09061Cannabidiol3Completed1
DB00575Clonidine3Unknown Status1
DB14098Cobalamin3Completed1
DB00470Dronabinol3Completed1
DB00476Duloxetine3Completed3
DB00813Fentanyl3Completed1
DB00996Gabapentin3Completed1
DB01221Ketamine3Unknown Status1
DB06218Lacosamide3Completed2
DB00379Mexiletine3Completed1
DB00486Nabilone3Unknown Status1
DB14011Nabiximols3Completed1
DB00230Pregabalin3Completed2
DB00230Pregabalin3Unknown Status1
DB05327Ranirestat3Completed1
DB12811Ranirestat3Completed1
DB00412Rosiglitazone3Completed1
DB11829Ruboxistaurin3Completed3
DB06204Tapentadol3Completed1
DB00152Thiamine3Completed1
DB00193Tramadol3Completed1
DB00316Acetaminophen4Completed1
DB01432Cholestyramine4Completed1
DB00476Duloxetine4Completed2
DB00996Gabapentin4Completed3
DB00281Lidocaine4Completed2
DB00166Lipoic acid4Completed1
DB00486Nabilone4Completed1
DB09539Omega-3-acid ethyl esters4Completed1
DB00230Pregabalin4Completed1
DB00203Sildenafil4Completed1
DB00193Tramadol4Completed1
DB00102BecaplerminNot AvailableCompleted1
DB00169CholecalciferolNot AvailableCompleted1
DB11094Vitamin DNot AvailableCompleted1