Non-small Cell Lung Cancer (NSCLC), Stage IV

Also known as: Non-small-cell Lung Cancer (NSCLC) Stage IV / Stage 4 Non-small cell lung cancer / Lung Cancer Non-small Cell Stage IV / Non-small Cell Lung Cancer (NSCLC) Stage IV / Non-small cell lung cancer stage IV / Non-small cell lung cancer metastatic

DrugDrug NameDrug Description
DB00441GemcitabineGemcitabine is a nucleoside analog used as chemotherapy. It is marketed as Gemzar® by Eli Lilly and Company. As with fluorouracil and other analogues of pyrimidines, the drug replaces one of the building blocks of nucleic acids, in this case cytidine, during DNA replication. The process arrests tumor growth, as new nucleosides cannot be attached to the "faulty" nucleoside, resulting in apoptosis (cellular "suicide"). Gemcitabine is used in various carcinomas: non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It is being investigated for use in oesophageal cancer, and is used experimentally in lymphomas and various other tumor types.
DrugDrug NamePhaseStatusCount
DB05928Dovitinib1Terminated1
DB00530Erlotinib1Terminated1
DB09330Osimertinib2Recruiting1
DB00958Carboplatin3Recruiting2
DB06643Denosumab3Active Not Recruiting1
DB12349Dulanermin3Active Not Recruiting1
DB01229Paclitaxel3Recruiting1
DB00642Pemetrexed3Recruiting1