Cytochrome P-450 CYP2E1 Substrates

DrugDrug NameDrug Description
DB00228EnfluraneA halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery.
DB00356ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
DB00753IsofluraneAn inhaled general anesthetic used in surgery.
DB00898EthanolFor therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
DB01028MethoxyfluraneFor use in the induction and maintenance of general anesthesia
DB01159HalothaneA general inhalation anesthetic used for the induction and maintenance of general anesthesia.
DB01236SevofluraneA inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB06728AnilineAniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor...
DB06770Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB00593EthosuximideAn anticonvulsant used to treat petit mal seizures.
DB06712NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
DB00347TrimethadioneAn anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures.
DB09288PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
DB14046DichlorobenzeneDichlorobenzene refers to any of, or a mixture of, three isomers consisting of benzene in which two of the hydrogen atoms are replaced by chlorine atoms: ortho-, meta-, and paradichlorobenzene....
DB00851DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
DB00904OndansetronA serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
DB00949FelbamateAn anticonvulsant used to treat severe epilepsy.
DB02701NicotinamideAn ingredient found in a variety of cosmetic products.
DB00184NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
DB01204MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
DB01213FomepizoleAn inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
DB00277TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
DB00951IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
DB00250DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
DB04977PlitidepsinIntended for the treatment of various forms of cancer.
DB05708GTS-21Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders.
DB00468QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
DB01041ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
DB05109TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
DB01136CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
DB00201CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
DB01223AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
DB01156BupropionA norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
DB00655EstroneAn estrogen used to treat perimenopausal and postmenopausal symptoms.
DB00773EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
DB00379MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB03783PhenacetinUsed principally as an analgesic.
DB01435AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
DB01174PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
DB00203SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DB00675TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
DB01412Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
DB01198ZopicloneA nonbenzodiazepine hypnotic used for the short-term management of insomnia.
DB00617ParamethadioneUsed for the control of absence (petit mal) seizures that are refractory to treatment with other medications.
DB04946IloperidoneAn atypical antipsychotic agent used for the acute treatment of schizophrenia in adults.
DB00918AlmotriptanA 5-HT1B/1D receptor agonist used to treat migraines.
DB06774CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
DB04920ClevidipineA dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
DB00633DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
DB00109EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
DB04858TirapazamineFor the treatment of head and neck cancer.
DB06637DalfampridineA potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS).
DB08868FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS).
DB04379N-Methyl-N-(Methylbenzyl)FormamideNot Available
DB01154ThiamylalUsed for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
DB09256TegafurAn antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
DB139631,2-dichlorobenzene1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound...
DB01844N,N-dimethylformamideNot Available
DB04856DexloxiglumideFor the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD).
DB00661VerapamilA calcium channel blocker used for the short-term treatment of angina, arrhythmia, and hypertension.
DrugDrug NameTargetType
DB00228EnfluraneCalcium-transporting ATPase type 2C member 1target
DB00228EnfluraneGlycine receptor (alpha-1/beta)target
DB00228EnfluraneGlutamate receptor 1target
DB00228EnfluranePotassium voltage-gated channel subfamily A member 1target
DB00228EnfluraneATP synthase subunit delta, mitochondrialtarget
DB00228EnfluraneIntermediate conductance calcium-activated potassium channel protein 4target
DB00228EnfluraneCytochrome P450 2E1enzyme
DB00228EnfluraneSerum albumincarrier
DB00228EnfluraneGABA-A receptor (anion channel)target
DB00356ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
DB00356ChlorzoxazoneCytochrome P450 2E1enzyme
DB00356ChlorzoxazoneCytochrome P450 1A2enzyme
DB00356ChlorzoxazoneCytochrome P450 2A6enzyme
DB00356ChlorzoxazoneCytochrome P450 1A1enzyme
DB00356ChlorzoxazoneCytochrome P450 2D6enzyme
DB00356ChlorzoxazoneCytochrome P450 3A4enzyme
DB00753IsofluraneCalcium-transporting ATPase type 2C member 1target
DB00753IsofluraneATP synthase subunit delta, mitochondrialtarget
DB00753IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB00753IsofluranePotassium voltage-gated channel subfamily A member 1target
DB00753IsofluraneGlutamate receptor 1target
DB00753IsofluraneGlycine receptor subunit alpha-1target
DB00753IsofluraneCalmodulintarget
DB00753IsofluraneCytochrome P450 2E1enzyme
DB00753IsofluraneSerum albumincarrier
DB00753IsofluraneCytochrome P450 2B6enzyme
DB00753IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
DB00753IsofluraneGABA-A receptor (anion channel)target
DB00753IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
DB00753IsofluraneNeuronal acetylcholine receptor subunit beta-2target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-1target
DB00898EthanolGlutamate receptor ionotropic, NMDA 3Atarget
DB00898EthanolGlycine receptor subunit alpha-1target
DB00898EthanolGlycine receptor subunit alpha-2target
DB00898EthanolCytochrome P450 2E1enzyme
DB00898EthanolCytochrome P450 1A1enzyme
DB00898EthanolCytochrome P450 1A2enzyme
DB00898EthanolCytochrome P450 2B6enzyme
DB00898EthanolCytochrome P450 2C19enzyme
DB00898EthanolCytochrome P450 2C9enzyme
DB00898EthanolCytochrome P450 3A4enzyme
DB00898EthanolCytochrome P450 4A11enzyme
DB00898EthanolAlcohol dehydrogenase 1Aenzyme
DB00898EthanolAlcohol dehydrogenase 1Benzyme
DB00898EthanolAlcohol dehydrogenase 1Cenzyme
DB00898EthanolAlcohol dehydrogenase class-3enzyme
DB00898EthanolVoltage-dependent L-type calcium channel subunit beta-1target
DB00898Ethanol5-hydroxytryptamine receptor 3Atarget
DB00898EthanolAlcohol dehydrogenase 4enzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-2target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-10target
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-5target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-4target
DB00898EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-3target
DB00898EthanolGlutamate receptor 1target
DB00898EthanolVoltage-dependent calcium channel gamma-1 subunittarget
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-2target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-6target
DB00898EthanolGlutamate receptor 2target
DB00898EthanolGlutamate receptor 4target
DB00898EthanolGlutamate receptor 3target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-4target
DB00898EthanolNeuronal acetylcholine receptor subunit beta-2target
DB00898EthanolG protein-activated inward rectifier potassium channel 1target
DB00898EthanolG protein-activated inward rectifier potassium channel 2target
DB00898EthanolVascular cell adhesion protein 1target
DB00898EthanolEquilibrative nucleoside transporter 1target
DB00898EthanolG protein-activated inward rectifier potassium channel 4target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-7target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-9target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-1target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-2target
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00898EthanolAlcohol dehydrogenase 6enzyme
DB00898EthanolNeuronal acetylcholine receptor subunit beta-4target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-3target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-5target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-6target
DB00898EthanolNeuronal acetylcholine receptor subunit beta-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit gamma-1target
DB00898EthanolGamma-aminobutyric acid receptor subunit gamma-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit epsilontarget
DB00898EthanolGamma-aminobutyric acid receptor subunit pitarget
DB00898EthanolGamma-aminobutyric acid receptor subunit thetatarget
DB00898EthanolGamma-aminobutyric acid receptor subunit deltatarget
DB00898EthanolAlcohol dehydrogenase [NADP(+)]enzyme
DB00898EthanolEquilibrative nucleoside transporter 2target
DB00898Ethanol5-hydroxytryptamine receptor 3Etarget
DB00898Ethanol5-hydroxytryptamine receptor 3Btarget
DB00898Ethanol5-hydroxytryptamine receptor 3Dtarget
DB00898Ethanol5-hydroxytryptamine receptor 3Ctarget
DB00898EthanolVoltage-dependent calcium channel gamma-2 subunittarget
DB00898EthanolG protein-activated inward rectifier potassium channel 3target
DB00898EthanolNeural cell adhesion molecule L1target
DB01028MethoxyfluraneCalcium-transporting ATPase type 2C member 1target
DB01028MethoxyfluraneATP synthase subunit delta, mitochondrialtarget
DB01028MethoxyfluraneNADH-ubiquinone oxidoreductase chain 1target
DB01028MethoxyfluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB01028MethoxyfluranePotassium voltage-gated channel subfamily A member 1target
DB01028MethoxyfluraneGlutamate receptor 1target
DB01028MethoxyfluraneGlycine receptor subunit alpha-1target
DB01028MethoxyfluraneCytochrome P450 2E1enzyme
DB01028MethoxyfluraneCytochrome P450 1A2enzyme
DB01028MethoxyfluraneCytochrome P450 2A6enzyme
DB01028MethoxyfluraneCytochrome P450 2B6enzyme
DB01028MethoxyfluraneCytochrome P450 2C9enzyme
DB01028MethoxyfluraneCytochrome P450 2D6enzyme
DB01028MethoxyfluraneCytochrome P450 3A4enzyme
DB01028MethoxyfluraneGABA-A receptor (anion channel)target
DB01159HalothaneGamma-aminobutyric acid receptor subunit alpha-1target
DB01159HalothaneGlycine receptor subunit alpha-1target
DB01159HalothaneCalcium-activated potassium channel subunit alpha-1target
DB01159HalothaneCalcium-transporting ATPase type 2C member 1target
DB01159HalothaneNADH-ubiquinone oxidoreductase chain 1target
DB01159HalothaneIntermediate conductance calcium-activated potassium channel protein 4target
DB01159HalothaneATP synthase subunit delta, mitochondrialtarget
DB01159HalothaneRhodopsintarget
DB01159HalothaneG protein-activated inward rectifier potassium channel 2target
DB01159HalothaneG protein-activated inward rectifier potassium channel 1target
DB01159HalothaneGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2target
DB01159HalothaneNeuropeptide S receptortarget
DB01159HalothaneCytochrome P450 2E1enzyme
DB01159HalothaneCytochrome P450 2A6enzyme
DB01159HalothaneCytochrome P450 3A4enzyme
DB01159HalothaneGlutamate receptor ionotropic, NMDA 3Atarget
DB01159HalothaneGlutamate receptor ionotropic, NMDA 3Btarget
DB01159HalothaneGlutamate receptor ionotropic, NMDA 2Atarget
DB01159HalothanePotassium channel subfamily K member 3target
DB01159HalothanePotassium channel subfamily K member 9target
DB01159HalothaneSerum albumincarrier
DB01159HalothaneCytochrome P450 2B6enzyme
DB01159HalothaneCytochrome P450 2C9enzyme
DB01159HalothaneGABA-A receptor (anion channel)target
DB01236SevofluraneCalcium-transporting ATPase type 2C member 1target
DB01236SevofluraneNADH-ubiquinone oxidoreductase chain 1target
DB01236SevofluraneGlycine receptor subunit alpha-1target
DB01236SevofluraneGlutamate receptor 1target
DB01236SevofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB01236SevofluranePotassium voltage-gated channel subfamily A member 1target
DB01236SevofluraneATP synthase subunit delta, mitochondrialtarget
DB01236SevofluraneCytochrome P450 2E1enzyme
DB01236SevofluraneSerum albumincarrier
DB01236SevofluraneCytochrome P450 2A6enzyme
DB01236SevofluraneCytochrome P450 2B6enzyme
DB01236SevofluraneCytochrome P450 3A4enzyme
DB01236SevofluraneGABA-A receptor (anion channel)target
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB06728AnilineCytochrome P450 2E1enzyme
DB06728AnilineKallikrein-1target
DB06728AnilineSerum albumintarget
DB06770Benzyl alcoholCytochrome P450 2C8enzyme
DB06770Benzyl alcoholCytochrome P450 1A1enzyme
DB06770Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
DB06770Benzyl alcoholCytochrome P450 1A2enzyme
DB06770Benzyl alcoholCytochrome P450 2E1enzyme
DB06770Benzyl alcoholCytochrome P450 2D6enzyme
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB00593EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00593EthosuximideCytochrome P450 3A4enzyme
DB00593EthosuximideCytochrome P450 2E1enzyme
DB00593EthosuximideCytochrome P450 3A Subfamilyenzyme
DB06712NilvadipineCytochrome P450 3A4enzyme
DB06712NilvadipineCytochrome P450 2A6enzyme
DB06712NilvadipineCytochrome P450 2C19enzyme
DB06712NilvadipineCytochrome P450 2C8enzyme
DB06712NilvadipineCytochrome P450 2E1enzyme
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00347TrimethadioneVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00347TrimethadioneCytochrome P450 2C19enzyme
DB00347TrimethadioneCytochrome P450 2C8enzyme
DB00347TrimethadioneCytochrome P450 2C9enzyme
DB00347TrimethadioneCytochrome P450 2E1enzyme
DB00347TrimethadioneCytochrome P450 3A4enzyme
DB09288PropacetamolCholinesteraseenzyme
DB09288PropacetamolProstaglandin G/H synthase 1target
DB09288PropacetamolProstaglandin G/H synthase 2target
DB09288PropacetamolTransient receptor potential cation channel subfamily V member 1target
DB09288PropacetamolCannabinoid receptor 1target
DB09288PropacetamolCytochrome P450 2E1enzyme
DB09288PropacetamolCytochrome P450 1A2enzyme
DB09288PropacetamolCytochrome P450 2D6enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-1enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-6enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-9enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 2B15enzyme
DB09288PropacetamolUDP-glucuronosyltransferase 1-10enzyme
DB09288PropacetamolSulfotransferase 1A1enzyme
DB09288PropacetamolSulfotransferase 1A3/1A4enzyme
DB09288PropacetamolEstrogen sulfotransferaseenzyme
DB09288PropacetamolBile salt sulfotransferaseenzyme
DB09288PropacetamolArylamine N-acetyltransferase 2enzyme
DB09288PropacetamolCytochrome P450 2C9enzyme
DB09288PropacetamolCytochrome P450 3A4enzyme
DB14046DichlorobenzeneCytochrome P450 2E1enzyme
DB00851DacarbazineDNA polymerase alpha subunit Btarget
DB00851DacarbazineCytochrome P450 1A1enzyme
DB00851DacarbazineCytochrome P450 1A2enzyme
DB00851DacarbazineCytochrome P450 2E1enzyme
DB00851Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00851DacarbazineDNAtarget
DB00904Ondansetron5-hydroxytryptamine receptor 3Atarget
DB00904OndansetronCytochrome P450 3A4enzyme
DB00904OndansetronCytochrome P450 1A2enzyme
DB00904OndansetronCytochrome P450 2D6enzyme
DB00904OndansetronCytochrome P450 3A5enzyme
DB00904OndansetronCytochrome P450 3A7enzyme
DB00904Ondansetron5-hydroxytryptamine receptor 4target
DB00904Ondansetron5-hydroxytryptamine receptor 1Atarget
DB00904Ondansetron5-hydroxytryptamine receptor 1Btarget
DB00904OndansetronMu-type opioid receptortarget
DB00904OndansetronCytochrome P450 2C9enzyme
DB00904OndansetronCytochrome P450 2E1enzyme
DB00949FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
DB00949FelbamateCytochrome P450 2C19enzyme
DB00949FelbamateCytochrome P450 3A4enzyme
DB00949FelbamateCytochrome P450 2E1enzyme
DB00949FelbamateCytochrome P450 2C9enzyme
DB02701NicotinamideNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
DB02701NicotinamideADP-ribosyl cyclase 2target
DB02701NicotinamideExotoxin Atarget
DB02701NicotinamideL-lactate dehydrogenase A chaintarget
DB02701NicotinamidePoly [ADP-ribose] polymerase 1target
DB02701NicotinamideCytochrome P450 2D6enzyme
DB02701NicotinamideCytochrome P450 2E1enzyme
DB02701NicotinamideCytochrome P450 3A4enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-2target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-2target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-7target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-10target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-9target
DB00184NicotineCytochrome P450 2A6enzyme
DB00184NicotineCytochrome P450 2E1enzyme
DB00184NicotineCytochrome P450 2A13enzyme
DB00184NicotineCytochrome P450 2B6enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit beta-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-3target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-5target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-6target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-3target
DB00184NicotineSolute carrier family 22 member 2transporter
DB00184NicotineSolute carrier family 22 member 1transporter
DB00184NicotineSolute carrier family 22 member 3transporter
DB00184NicotineSolute carrier family 22 member 5transporter
DB00184NicotineSolute carrier family 22 member 4transporter
DB00184NicotineCytochrome P450 1A1enzyme
DB00184NicotineCytochrome P450 1A2enzyme
DB00184NicotineCytochrome P450 2C19enzyme
DB00184NicotineCytochrome P450 2C8enzyme
DB00184NicotineCytochrome P450 2C9enzyme
DB00184NicotineCytochrome P450 2D6enzyme
DB00184NicotineCytochrome P450 3A4enzyme
DB00184NicotineAmine oxidase [flavin-containing] Aenzyme
DB00184NicotineAmine oxidase [flavin-containing] Benzyme
DB00184NicotineCytochrome P450 19A1target
DB00184NicotineCholine O-acetyltransferasetarget
DB01204MitoxantroneDNA topoisomerase 2-alphatarget
DB01204MitoxantroneCytochrome P450 2E1enzyme
DB01204MitoxantroneP-glycoprotein 1transporter
DB01204MitoxantroneMultidrug resistance-associated protein 1transporter
DB01204MitoxantroneATP-binding cassette sub-family G member 2transporter
DB01204MitoxantroneDNAtarget
DB01204MitoxantroneCytochrome P450 1B1enzyme
DB01204MitoxantroneCytochrome P450 3A4enzyme
DB01213FomepizoleAlcohol dehydrogenase 1Atarget
DB01213FomepizoleAlcohol dehydrogenase 1Btarget
DB01213FomepizoleAlcohol dehydrogenase 1Ctarget
DB01213FomepizoleCatalasetarget
DB01213FomepizoleCytochrome P450 2E1enzyme
DB01213FomepizoleCytochrome P450 2A6enzyme
DB00277TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00277TheophyllineAdenosine receptor A2btarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00277TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00277TheophyllineAdenosine receptor A1target
DB00277TheophyllineAdenosine receptor A2atarget
DB00277TheophyllineCytochrome P450 1A2enzyme
DB00277TheophyllineAdenosine deaminaseenzyme
DB00277TheophyllineCytochrome P450 2E1enzyme
DB00277TheophyllineCytochrome P450 3A4enzyme
DB00277TheophyllineSolute carrier family 22 member 7transporter
DB00277TheophyllineCytochrome P450 1A1enzyme
DB00277TheophyllineCytochrome P450 1B1enzyme
DB00277TheophyllineCytochrome P450 2D6enzyme
DB00277TheophyllineHistone deacetylase 2target
DB00277TheophyllineCopine-1target
DB00277TheophyllineMinor histocompatibility antigen H13target
DB00277TheophyllineNodal modulator 1target
DB00277TheophyllinePoly [ADP-ribose] polymerase 1target
DB00277TheophyllineProtein RIC-3target
DB00277TheophyllineTubulin monoglycylase TTLL3target
DB00951IsoniazidCatalase-peroxidasetarget
DB00951IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB00951IsoniazidCytochrome P450 2E1enzyme
DB00951IsoniazidCytochrome P450 1A2enzyme
DB00951IsoniazidCytochrome P450 2C9enzyme
DB00951IsoniazidCytochrome P450 2D6enzyme
DB00951IsoniazidCytochrome P450 2C19enzyme
DB00951IsoniazidArylamine N-acetyltransferase 2enzyme
DB00951IsoniazidArylamine N-acetyltransferaseenzyme
DB00951IsoniazidCytochrome P450 2A6enzyme
DB00951IsoniazidCytochrome P450 2C8enzyme
DB00951IsoniazidCytochrome P450 2C8target
DB00951IsoniazidCytochrome P450 1A2target
DB00951IsoniazidCytochrome P450 3A4target
DB00951IsoniazidCytochrome P450 2C19target
DB00951IsoniazidDihydrofolate reductasetarget
DB00951IsoniazidSerum albumincarrier
DB00250DapsoneInactive dihydropteroate synthase 2target
DB00250DapsoneDihydropteroate synthase 1target
DB00250DapsoneCytochrome P450 2C9enzyme
DB00250DapsoneCytochrome P450 2E1enzyme
DB00250DapsoneCytochrome P450 3A4enzyme
DB00250DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00250DapsoneProstaglandin G/H synthase 1enzyme
DB00250DapsoneProstaglandin G/H synthase 2enzyme
DB00250DapsoneCytochrome P450 2C8enzyme
DB00250DapsoneCytochrome P450 2C19enzyme
DB00250DapsoneArylamine N-acetyltransferase 2enzyme
DB00250DapsoneCytochrome P450 3A5enzyme
DB00250DapsoneCytochrome P450 3A7enzyme
DB00250DapsoneMyeloperoxidaseenzyme
DB00250DapsoneCytochrome P450 2C18enzyme
DB04977PlitidepsinCytochrome P450 3A4enzyme
DB04977PlitidepsinCytochrome P450 2A6enzyme
DB04977PlitidepsinCytochrome P450 2E1enzyme
DB04977PlitidepsinCytochrome P450 4A11enzyme
DB05708GTS-21Neuronal acetylcholine receptor subunit alpha-7target
DB05708GTS-21Cytochrome P450 1A2enzyme
DB05708GTS-21Cytochrome P450 2E1enzyme
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineP-glycoprotein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB01041ThalidomideTumor necrosis factortarget
DB01041ThalidomideNuclear factor NF-kappa-B p105 subunittarget
DB01041ThalidomideProstaglandin G/H synthase 2target
DB01041ThalidomideCytochrome P450 2C19enzyme
DB01041ThalidomideCytochrome P450 1A1enzyme
DB01041ThalidomideCytochrome P450 2E1enzyme
DB01041ThalidomideCytochrome P450 2C9enzyme
DB01041ThalidomideProstaglandin G/H synthase 1enzyme
DB01041ThalidomideProstaglandin G/H synthase 2enzyme
DB01041ThalidomideCytochrome P450 3A5enzyme
DB01041ThalidomideFibroblast growth factor receptor 2target
DB01041ThalidomideDNAtarget
DB01041ThalidomideProtein cereblontarget
DB01041Thalidomidealpha1-acid glycoproteintarget
DB05109TrabectedinCytochrome P450 3A4enzyme
DB05109TrabectedinCytochrome P450 2C9enzyme
DB05109TrabectedinCytochrome P450 2D6enzyme
DB05109TrabectedinCytochrome P450 2E1enzyme
DB05109TrabectedinCytochrome P450 2C19enzyme
DB05109TrabectedinDNAtarget
DB05109TrabectedinProstaglandin G/H synthase 1enzyme
DB01136CarvedilolAlpha-1A adrenergic receptortarget
DB01136CarvedilolBeta-1 adrenergic receptortarget
DB01136CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
DB01136CarvedilolBeta-2 adrenergic receptortarget
DB01136CarvedilolVascular endothelial growth factor Atarget
DB01136CarvedilolNatriuretic peptides Btarget
DB01136CarvedilolGap junction alpha-1 proteintarget
DB01136CarvedilolPotassium voltage-gated channel subfamily H member 2target
DB01136CarvedilolVascular cell adhesion protein 1target
DB01136CarvedilolCytochrome P450 2C9enzyme
DB01136CarvedilolCytochrome P450 2D6enzyme
DB01136CarvedilolXanthine dehydrogenase/oxidaseenzyme
DB01136CarvedilolP-glycoprotein 1transporter
DB01136CarvedilolCytochrome P450 1A2enzyme
DB01136CarvedilolCytochrome P450 3A4enzyme
DB01136CarvedilolCytochrome P450 1A1enzyme
DB01136CarvedilolCytochrome P450 2E1enzyme
DB01136CarvedilolAlpha-1D adrenergic receptortarget
DB01136CarvedilolAlpha-1B adrenergic receptortarget
DB01136CarvedilolAlpha-2C adrenergic receptortarget
DB01136CarvedilolAlpha-2B adrenergic receptortarget
DB01136CarvedilolAlpha-2A adrenergic receptortarget
DB01136CarvedilolE-selectintarget
DB01136CarvedilolHypoxia-inducible factor 1-alphatarget
DB01136CarvedilolInward rectifier potassium channel 4target
DB01136CarvedilolUDP-glucuronosyltransferase 1-1enzyme
DB01136CarvedilolSerum albumincarrier
DB01136CarvedilolUDP-glucuronosyltransferase 2B4enzyme
DB01136CarvedilolUDP-glucuronosyltransferase 2B7enzyme
DB01136CarvedilolInward rectifier potassium channel 2target
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00201CaffeineATP-binding cassette sub-family G member 2transporter
DB00201CaffeineAdenosine receptor A2btarget
DB00201CaffeineAdenosine receptor A3target
DB00201CaffeinePhosphodiesterase enzymestarget
DB01223AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01223AminophyllineAdenosine receptor A3target
DB01223AminophyllineAdenosine receptor A1target
DB01223AminophyllineCytochrome P450 1A2enzyme
DB01223AminophyllineCytochrome P450 2E1enzyme
DB01223AminophyllineCytochrome P450 3A4enzyme
DB01223AminophyllineHistone deacetylase 2target
DB01156BupropionSodium-dependent dopamine transportertarget
DB01156BupropionSodium-dependent noradrenaline transportertarget
DB01156BupropionCytochrome P450 2B6enzyme
DB01156BupropionCytochrome P450 2D6enzyme
DB01156BupropionAlpha-1-acid glycoprotein 1carrier
DB01156BupropionNeuronal acetylcholine receptor subunit alpha-3target
DB01156BupropionCytochrome P450 2C9enzyme
DB01156BupropionCytochrome P450 2E1enzyme
DB01156BupropionSolute carrier family 22 member 2transporter
DB01156Bupropion5-hydroxytryptamine receptor 3Atarget
DB00655EstroneEstrogen receptor alphatarget
DB00655EstroneCytochrome P450 1A2enzyme
DB00655EstroneCytochrome P450 1A1enzyme
DB00655EstroneSerum albumincarrier
DB00655EstroneSolute carrier organic anion transporter family member 2B1transporter
DB00655EstroneP-glycoprotein 1transporter
DB00655EstroneSolute carrier organic anion transporter family member 1A2transporter
DB00655EstroneATP-binding cassette sub-family G member 2transporter
DB00655EstroneSolute carrier organic anion transporter family member 1B1transporter
DB00655EstroneCytochrome P450 3A4enzyme
DB00655EstroneCytochrome P450 1B1enzyme
DB00655EstroneCytochrome P450 2B6enzyme
DB00655EstroneCytochrome P450 2C9enzyme
DB00655EstroneCytochrome P450 2E1enzyme
DB00655EstroneCytochrome P450 3A5enzyme
DB00655EstroneEstrogen receptor betatarget
DB00655EstroneAndrogen receptortarget
DB00655EstroneCytochrome P450 19A1target
DB00655EstroneSex hormone-binding globulintarget
DB00655EstroneSolute carrier family 22 member 8transporter
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideP-glycoprotein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB00379MexiletineSodium channel protein type 5 subunit alphatarget
DB00379MexiletineCytochrome P450 1A2enzyme
DB00379MexiletineCytochrome P450 2D6enzyme
DB00379MexiletineCytochrome P450 2B6enzyme
DB00379MexiletineCytochrome P450 2E1enzyme
DB00379MexiletineCytochrome P450 3A4enzyme
DB00379MexiletineAryl hydrocarbon receptortarget
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB03783PhenacetinProstaglandin G/H synthase 1target
DB03783PhenacetinCytochrome P450 1A2enzyme
DB03783PhenacetinCytochrome P450 2D6enzyme
DB03783PhenacetinSolute carrier family 22 member 6transporter
DB03783PhenacetinCytochrome P450 1A1enzyme
DB03783PhenacetinCytochrome P450 2A13enzyme
DB03783PhenacetinCytochrome P450 2A6enzyme
DB03783PhenacetinCytochrome P450 2C19enzyme
DB03783PhenacetinCytochrome P450 2C9enzyme
DB03783PhenacetinCytochrome P450 2E1enzyme
DB03783PhenacetinCytochrome P450 3A4enzyme
DB01435AntipyrineCytochrome P450 2C8enzyme
DB01435AntipyrineCytochrome P450 2C9enzyme
DB01435AntipyrineCytochrome P450 1A2enzyme
DB01435AntipyrineCytochrome P450 2C19enzyme
DB01435AntipyrineCytochrome P450 3A4enzyme
DB01435AntipyrineSolute carrier family 22 member 6transporter
DB01435AntipyrineCytochrome P450 2A6enzyme
DB01435AntipyrineCytochrome P450 2B6enzyme
DB01435AntipyrineCytochrome P450 2C18enzyme
DB01435AntipyrineCytochrome P450 2D6enzyme
DB01435AntipyrineCytochrome P450 2E1enzyme
DB01435AntipyrineProstaglandin G/H synthase 2target
DB01435AntipyrineProstaglandin G/H synthase 1target
DB01174PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01174PhenobarbitalCytochrome P450 2C19enzyme
DB01174PhenobarbitalCytochrome P450 2C9enzyme
DB01174PhenobarbitalCytochrome P450 2B6enzyme
DB01174PhenobarbitalCytochrome P450 2C8enzyme
DB01174PhenobarbitalCytochrome P450 1A2enzyme
DB01174PhenobarbitalCytochrome P450 3A4enzyme
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
DB01174PhenobarbitalBile salt export pumptransporter
DB01174PhenobarbitalP-glycoprotein 1transporter
DB01174PhenobarbitalMultidrug resistance-associated protein 1transporter
DB01174PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01174PhenobarbitalGlutamate receptor 2target
DB01174PhenobarbitalGlutamate receptor ionotropic, kainate 2target
DB01174PhenobarbitalCytochrome P450 2A6enzyme
DB01174PhenobarbitalCytochrome P450 2E1enzyme
DB01174PhenobarbitalCytochrome P450 3A5enzyme
DB01174PhenobarbitalCytochrome P450 1A1enzyme
DB01174PhenobarbitalCytochrome P450 2C18enzyme
DB01174PhenobarbitalCytochrome P450 3A7enzyme
DB01174PhenobarbitalCytochrome P450 4B1enzyme
DB01174PhenobarbitalNMDA receptortarget
DB01174PhenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
DB01174PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilP-glycoprotein 1transporter
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenP-glycoprotein 1transporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DB00675TamoxifenBile salt export pumptransporter
DB00675TamoxifenThyroxine-binding globulincarrier
DB00675TamoxifenBile salt sulfotransferaseenzyme
DB00675TamoxifenCytochrome P450 1A2enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 2B7enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 2B17enzyme
DB00675TamoxifenEstrogen sulfotransferaseenzyme
DB00675TamoxifenATP-binding cassette sub-family A member 1transporter
DB00675TamoxifenMitogen-activated protein kinase 8target
DB00675TamoxifenSerum albumincarrier
DB01412TheobromineCytochrome P450 1A2enzyme
DB01412TheobromineCytochrome P450 2E1enzyme
DB01412TheobromineAdenosine receptor A1target
DB01412TheobromineAdenosine receptor A2atarget
DB01412TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01198ZopicloneTranslocator proteintarget
DB01198ZopicloneCytochrome P450 2C8enzyme
DB01198ZopicloneCytochrome P450 2C9enzyme
DB01198ZopicloneCytochrome P450 3A4enzyme
DB01198ZopicloneProstaglandin G/H synthase 1enzyme
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-1target
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-2target
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-3target
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-5target
DB01198ZopicloneCytochrome P450 2E1enzyme
DB00617ParamethadioneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00617ParamethadioneCytochrome P450 2C9enzyme
DB00617ParamethadioneCytochrome P450 2C8enzyme
DB00617ParamethadioneCytochrome P450 2E1enzyme
DB00617ParamethadioneCytochrome P450 3A4enzyme
DB04946IloperidoneDopamine D2 receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 2Atarget
DB04946IloperidoneCytochrome P450 2D6enzyme
DB04946IloperidoneCytochrome P450 3A4enzyme
DB04946IloperidoneCytochrome P450 3A5enzyme
DB04946IloperidoneCytochrome P450 3A7enzyme
DB04946IloperidoneCytochrome P450 2E1enzyme
DB04946IloperidoneDopamine D3 receptortarget
DB04946IloperidoneAlpha-1A adrenergic receptortarget
DB04946IloperidoneDopamine D4 receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 6target
DB04946Iloperidone5-hydroxytryptamine receptor 7target
DB04946IloperidoneHistamine H1 receptortarget
DB04946IloperidoneDopamine D1 receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 1Atarget
DB04946IloperidoneAlpha-2C adrenergic receptortarget
DB00918Almotriptan5-hydroxytryptamine receptor 1Dtarget
DB00918Almotriptan5-hydroxytryptamine receptor 1Btarget
DB00918AlmotriptanCytochrome P450 3A4enzyme
DB00918AlmotriptanCytochrome P450 2D6enzyme
DB00918AlmotriptanAmine oxidase [flavin-containing] Aenzyme
DB00918AlmotriptanDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00918AlmotriptanCytochrome P450 2C19enzyme
DB00918AlmotriptanCytochrome P450 2E1enzyme
DB00918AlmotriptanCytochrome P450 2C8enzyme
DB06774CapsaicinCytochrome P450 3A4enzyme
DB06774CapsaicinProstaglandin G/H synthase 2enzyme
DB06774CapsaicinMyeloperoxidaseenzyme
DB06774CapsaicinCytochrome P450 1A2enzyme
DB06774CapsaicinCytochrome P450 2E1enzyme
DB06774CapsaicinAmine oxidase [flavin-containing] Aenzyme
DB06774CapsaicinDopamine beta-hydroxylaseenzyme
DB06774CapsaicinGlutamine synthetaseenzyme
DB06774CapsaicinCholinesteraseenzyme
DB06774CapsaicinTransient receptor potential cation channel subfamily V member 1target
DB06774CapsaicinProhibitin-2target
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB04920ClevidipineCytochrome P450 2C9enzyme
DB04920ClevidipineCytochrome P450 2D6enzyme
DB04920ClevidipineCytochrome P450 2E1enzyme
DB04920ClevidipineCytochrome P450 2C19enzyme
DB04920ClevidipineCytochrome P450 3A4enzyme
DB04920ClevidipineCholinesteraseenzyme
DB00633DexmedetomidineAlpha-2A adrenergic receptortarget
DB00633DexmedetomidineCytochrome P450 2E1enzyme
DB00633DexmedetomidineCytochrome P450 1A2enzyme
DB00633DexmedetomidineCytochrome P450 1A1enzyme
DB00633DexmedetomidineCytochrome P450 2D6enzyme
DB00109EnfuvirtideEnvelope glycoproteintarget
DB00109EnfuvirtideCytochrome P450 2C19enzyme
DB00109EnfuvirtideCytochrome P450 2E1enzyme
DB04858TirapazamineDNAtarget
DB04858TirapazamineCytochrome P450 2E1enzyme
DB06637DalfampridineCytochrome P450 2E1enzyme
DB06637DalfampridinePotassium voltage-gated channel subfamily D member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily D member 3target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 1target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 4target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 3target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 5target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 6target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 7target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 10target
DB06637DalfampridinePotassium voltage-gated channel subfamily B member 1target
DB06637DalfampridinePotassium voltage-gated channel subfamily B member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily C member 1target
DB06637DalfampridinePotassium voltage-gated channel subfamily C member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily C member 3target
DB06637DalfampridinePotassium voltage-gated channel subfamily D member 1target
DB06637DalfampridineSolute carrier family 22 member 2transporter
DB08868FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
DB08868FingolimodSphingosine 1-phosphate receptor 5target
DB08868FingolimodSphingosine kinase 1enzyme
DB08868FingolimodCytochrome P450 2E1enzyme
DB08868FingolimodCytochrome P450 4F12enzyme
DB08868FingolimodHistone deacetylase 1target
DB04379N-Methyl-N-(Methylbenzyl)FormamideRenintarget
DB04379N-Methyl-N-(Methylbenzyl)FormamideCytochrome P450 2E1enzyme
DB01154ThiamylalGamma-aminobutyric acid receptor subunit alpha-1target
DB01154ThiamylalATP-sensitive inward rectifier potassium channel 8target
DB01154ThiamylalATP-sensitive inward rectifier potassium channel 11target
DB01154ThiamylalCytochrome P450 2C9enzyme
DB01154ThiamylalCytochrome P450 3A4enzyme
DB01154ThiamylalCytochrome P450 2E1enzyme
DB09256TegafurCytochrome P450 2A6enzyme
DB09256TegafurThymidylate synthasetarget
DB09256TegafurCytochrome P450 1A2enzyme
DB09256TegafurCytochrome P450 2C8enzyme
DB09256TegafurCytochrome P450 2E1enzyme
DB09256TegafurCytochrome P450 3A5enzyme
DB09256TegafurThyroxine-binding globulincarrier
DB139631,2-dichlorobenzeneCytochrome P450 2E1enzyme
DB01844N,N-dimethylformamideChymotrypsin-like elastase family member 1target
DB01844N,N-dimethylformamideRenintarget
DB01844N,N-dimethylformamideCytochrome P450 2E1enzyme
DB04856DexloxiglumideCholecystokinin receptor type Atarget
DB04856DexloxiglumideCytochrome P450 3A4enzyme
DB04856DexloxiglumideCytochrome P450 2C9enzyme
DB04856DexloxiglumideCytochrome P450 3A5enzyme
DB04856DexloxiglumideCytochrome P450 2B6enzyme
DB04856DexloxiglumideCytochrome P450 2E1enzyme
DB00661VerapamilSodium channel protein type 5 subunit alphatarget
DB00661VerapamilATP-sensitive inward rectifier potassium channel 11target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-4target
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-3target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-1target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-2target
DB00661VerapamilPotassium voltage-gated channel subfamily H member 2target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00661VerapamilCytochrome P450 1A2enzyme
DB00661VerapamilCytochrome P450 3A5enzyme
DB00661VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00661VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00661VerapamilSodium-dependent serotonin transportertarget
DB00661VerapamilCytochrome P450 3A4enzyme
DB00661VerapamilP-glycoprotein 1transporter
DB00661VerapamilSolute carrier family 22 member 1transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 2transporter
DB00661VerapamilMultidrug resistance-associated protein 4transporter
DB00661VerapamilSolute carrier family 22 member 5transporter
DB00661VerapamilMultidrug resistance-associated protein 1transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1A2transporter
DB00661VerapamilMultidrug resistance-associated protein 7transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 1transporter
DB00661VerapamilSolute carrier family 22 member 4transporter
DB00661VerapamilATP-binding cassette sub-family G member 2transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1B1transporter
DB00661VerapamilCytochrome P450 2C8enzyme
DB00661VerapamilCytochrome P450 2C9enzyme
DB00661VerapamilCytochrome P450 2B6enzyme
DB00661VerapamilCytochrome P450 2C19enzyme
DB00661VerapamilCytochrome P450 2D6enzyme
DB00661VerapamilAlpha-1A adrenergic receptortarget
DB00661VerapamilAlpha-1B adrenergic receptortarget
DB00661VerapamilAlpha-1D adrenergic receptortarget
DB00661VerapamilBile salt export pumptransporter
DB00661VerapamilSerum albumincarrier
DB00661VerapamilAlpha-1-acid glycoprotein 1carrier
DB00661VerapamilCytochrome P450 2C18enzyme
DB00661VerapamilCytochrome P450 2E1enzyme