Premature Births

Also known as: PreTerm Birth / Premature Birth / Birth premature / Premature birth, NOS / Early onset of delivery / Premature delivery / Premature baby / Baby premature / Immature baby / 28 completed weeks or more but less than 37 completed weeks (196 completed days but less than 259 completed days) of gestation. / Prematurity / Infant premature

DrugDrug NameDrug Description
DB06761BeractantA pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants.
DB06789Hydroxyprogesterone caproateA synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
DB01050IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DB09113Poractant alfaA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
DrugDrug NameTargetType
DB06789Hydroxyprogesterone caproateProgesterone receptortarget
DB06789Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
DB06789Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
DB06789Hydroxyprogesterone caproateCytochrome P450 2C19enzyme
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenP-glycoprotein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01050IbuprofenCytochrome P450 3A4enzyme
DrugDrug NamePhaseStatusCount
DB00695Furosemide0Recruiting1
DB00653Magnesium sulfate0Completed1
DB00127Spermine0Recruiting1
DB00443Betamethasone1Active Not Recruiting1
DB01234Dexamethasone1Active Not Recruiting1
DB113311-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))2Terminated1
DB00945Acetylsalicylic acid2Completed1
DB09114Colfosceril palmitate2Terminated1
DB00741Hydrocortisone2Completed1
DB00328Indomethacin2Unknown Status1
DB04897Lucinactant2Terminated1
DB01065Melatonin2Completed1
DB00916Metronidazole2Completed1
DB00929Misoprostol2Completed1
DB00471Montelukast2Completed1
DB03796Palmitic Acid2Terminated1
DB00396Progesterone2Completed1
DB00396Progesterone2Recruiting1
DB11332Sinapultide2Terminated1
DB00443Betamethasone2 / 3Recruiting1
DB01234Dexamethasone2 / 3Recruiting1
DB00378Dydrogesterone2 / 3Recruiting1
DB14570Hydroxyprogesterone2 / 3Recruiting1
DB06789Hydroxyprogesterone caproate2 / 3Completed1
DB06789Hydroxyprogesterone caproate2 / 3Recruiting1
DB01065Melatonin2 / 3Terminated1
DB00110Palivizumab2 / 3Completed1
DB00396Progesterone2 / 3Completed1
DB00396Progesterone2 / 3Not Yet Recruiting1
DB00396Progesterone2 / 3Recruiting1
DB00396Progesterone2 / 3Withdrawn2
DB00207Azithromycin3Completed1
DB00443Betamethasone3Active Not Recruiting1
DB00443Betamethasone3Withdrawn1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)3Completed1
DB10992Bordetella pertussis pertactin antigen (formaldehyde inactivated)3Completed1
DB10991Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)3Completed1
DB00201Caffeine3Completed1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)3Completed1
DB03756Doconexent3Recruiting1
DB14570Hydroxyprogesterone3Active Not Recruiting1
DB06789Hydroxyprogesterone caproate3Active Not Recruiting1
DB06789Hydroxyprogesterone caproate3Unknown Status1
DB14224Lactobacillus reuteri3Terminated1
DB11110Magnesium citrate3Recruiting1
DB11133Omega-3 fatty acids3Completed1
DB00388Phenylephrine3Terminated1
DB00396Progesterone3Completed4
DB00396Progesterone3Not Yet Recruiting1
DB00396Progesterone3Unknown Status1
DB00205Pyrimethamine3Completed1
DB01299Sulfadoxine3Completed1
DB00809Tropicamide3Terminated1
DB00945Acetylsalicylic acid4Completed1
DB00945Acetylsalicylic acid4Recruiting1
DB01060Amoxicillin4Recruiting1
DB04557Arachidonic Acid4Completed1
DB00207Azithromycin4Recruiting1
DB06755Beta carotene4Completed1
DB00112Bevacizumab4Completed1
DB00169Cholecalciferol4Completed1
DB01190Clindamycin4Completed1
DB01234Dexamethasone4Completed1
DB01234Dexamethasone4Recruiting1
DB09341Dextrose, unspecified form4Completed1
DB03756Doconexent4Completed1
DB01184Domperidone4Completed1
DB00016Erythropoietin4Completed1
DB06789Hydroxyprogesterone caproate4Recruiting1
DB00583Levocarnitine4Recruiting1
DB14513Magnesium4Completed1
DB01115Nifedipine4Completed2
DB00435Nitric Oxide4Completed1
DB00396Progesterone4Completed1
DB00396Progesterone4Recruiting3
DB01270Ranibizumab4Completed1
DB00867Ritodrine4Completed1
DB00162Vitamin A4Completed1
DB01593Zinc4Completed1
DB11175Zinc picolinate4Completed1
DB00945Acetylsalicylic acidNot AvailableActive Not Recruiting1
DB09059AtosibanNot AvailableCompleted1
DB06789Hydroxyprogesterone caproateNot AvailableCompleted1
DB06789Hydroxyprogesterone caproateNot AvailableWithdrawn2
DB00653Magnesium sulfateNot AvailableTerminated1
DB01115NifedipineNot AvailableTerminated1
DB00396ProgesteroneNot AvailableCompleted4
DB00396ProgesteroneNot AvailableRecruiting4
DB00396ProgesteroneNot AvailableTerminated2
DB00396ProgesteroneNot AvailableWithdrawn2