Showing BioInteractions for Diphenylpyraline (DB01146)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 2

	Interacting Group	Interacting Drugs
	Diphenylpyraline is a Histamine H1 receptor antagonist
1	Histamine H1 receptor antagonists	Aceprometazine, Acrivastine, Alcaftadine, Alimemazine, Amitriptyline, Amoxapine, Antazoline, Aripiprazole, Aripiprazole lauroxil, Asenapine, Astemizole, Azatadine, Azelastine, Benzatropine, Benzquinamide, Bepotastine, Bilastine, Bromodiphenhydramine, Brompheniramine, Buclizine, Butriptyline, Carbinoxamine, Cariprazine, Cetirizine, Chlorcyclizine, Chloropyramine, Chlorpheniramine, Chlorpromazine, Chlorprothixene, Cinnarizine, Clemastine, Clofedanol, Clozapine, Cyclizine, Cyproheptadine, Desipramine, Desloratadine, Dexbrompheniramine, Dexchlorpheniramine maleate, Dimenhydrinate, Dimetindene, Diphenhydramine, Dosulepin, Doxepin, Doxylamine, Emedastine, Epinastine, Fexofenadine, Flunarizine, Iloperidone, Imipramine, Isothipendyl, Ketotifen, Lamotrigine, Levocabastine, Levocetirizine, Loratadine, Lorpiprazole, Maprotiline, Meclizine, Mepyramine, Mequitazine, Methdilazine, Methotrimeprazine, Mianserin, Mirtazapine, Nortriptyline, Olanzapine, Olopatadine, Orphenadrine, Paliperidone, Phenindamine, Pizotifen, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Risperidone, Rupatadine, Terfenadine, Tesmilifene, Thonzylamine, Trazodone, Trimipramine, Tripelennamine, Triprolidine, Ziprasidone, Zuclopenthixol
2	Histamine H1 receptor inverse agonists	Esmirtazapine, Hydroxyzine, Perospirone, Pheniramine
3	Histamine H1 receptor agonists	Betahistine, Histamine, Tolazoline
4	Histamine H1 receptor inhibitors	Escitalopram, Levocetirizine, Paroxetine
5	Histamine H1 receptor binders	Citalopram, Loxapine

	Interacting Group	Interacting Drugs
	Diphenylpyraline is a Sodium-dependent dopamine transporter inhibitor
1	Sodium-dependent dopamine transporter inhibitors	4-Methoxyamphetamine, Armodafinil, Benzatropine, Benzphetamine, Bupropion, Chloroprocaine, Chlorpheniramine, Cocaine, Desvenlafaxine, Dexmethylphenidate, Diethylpropion, Duloxetine, Escitalopram, Etoperidone, Fencamfamin, Imipramine, Mazindol, Meperidine, Methylphenidate, Modafinil, Nefazodone, Phenmetrazine, Phentermine, Procaine, Pseudoephedrine, Sertraline, Sibutramine, Trimipramine, Venlafaxine
2	Sodium-dependent dopamine transporter negative modulators	Amphetamine, Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
3	Sodium-dependent dopamine transporter binders	Amoxapine, Loxapine, Mianserin, Sertraline
4	Sodium-dependent dopamine transporter inducers	Dopamine
5	Sodium-dependent dopamine transporter antagonists	Armodafinil
6	Sodium-dependent dopamine transporter modulators	Aripiprazole