Peripheral Arterial Disease (PAD)

Also known as: Peripheral Arterial Disease / Peripheral Arterial Diseases / Peripheral Arterial Disease(PAD) / Peripheral angiopathy / Peripheral obliterative arteriopathy / Peripheral arterial occlusive disease

DrugDrug NameDrug Description
DB00758ClopidogrelClopidogrel, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to inhibit blood clots in a variety of conditions such as peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Clopidogrel is sold under the name Plavix by Sanofi and Bristol-Myers Squibb. The drug is an irreversible inhibitor of the P2Y12 adenosine diphosphate receptor found on the membranes of platelet cells. Clopidogrel use is associated with several serious adverse drug reactions such as severe neutropenia, various forms of hemorrhage, and cardiovascular edema.
DB00806PentoxifyllineA methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production. [PubChem]
DB09030VorapaxarVorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
DrugDrug NamePhaseStatusCount
DB11720Angiotensin 1-70Active Not Recruiting1
DB00678Losartan0Completed1
DB01132Pioglitazone0Completed1
DB00641Simvastatin0Completed1
DB09153Sodium Chloride0Active Not Recruiting1
DB00126Ascorbic acid1Terminated1
DB01076Atorvastatin1Terminated1
DB09502Fludeoxyglucose F-181Recruiting1
DB12246Inclacumab1Completed1
DB05599Fibroblast growth factor-11 / 2Not Yet Recruiting1
DB00945Acetylsalicylic acid2Completed1
DB00758Clopidogrel2Completed1
DB09075Edoxaban2Completed1
DB06215Ferumoxytol2Active Not Recruiting1
DB00789Gadopentetic acid2Completed1
DB09374Indocyanine green acid form2Completed1
DB00155L-Citrulline2Unknown Status1
DB09112Nitrous acid2Completed1
DB09292Sacubitril2Recruiting1
DB00020Sargramostim2Completed1
DB00177Valsartan2Recruiting1
DB06629Zibotentan2Completed1
DB00758Clopidogrel2 / 3Recruiting1
DB00203Sildenafil2 / 3Not Yet Recruiting1
DB08816Ticagrelor2 / 3Recruiting1
DB00945Acetylsalicylic acid3Not Yet Recruiting1
DB00945Acetylsalicylic acid3Recruiting2
DB01166Cilostazol3Recruiting1
DB00758Clopidogrel3Completed1
DB00758Clopidogrel3Not Yet Recruiting1
DB00758Clopidogrel3Recruiting1
DB00973Ezetimibe3Completed1
DB09539Omega-3-acid ethyl esters3Completed1
DB00641Simvastatin3Completed1
DB00208Ticlopidine3Completed1
DB09030Vorapaxar3Completed1
DB00945Acetylsalicylic acid4Completed2
DB00945Acetylsalicylic acid4Recruiting2
DB00945Acetylsalicylic acid4Terminated1
DB00945Acetylsalicylic acid4Unknown Status1
DB09302Alirocumab4Recruiting1
DB00437Allopurinol4Completed1
DB01076Atorvastatin4Completed1
DB11121Chloroxylenol4Completed3
DB00169Cholecalciferol4Terminated1
DB01166Cilostazol4Completed2
DB01166Cilostazol4Terminated1
DB00758Clopidogrel4Completed3
DB00758Clopidogrel4Recruiting2
DB00758Clopidogrel4Unknown Status2
DB01234Dexamethasone4Completed1
DB00973Ezetimibe4Completed1
DB06703Gadobutrol4Completed1
DB09132Gadoteric acid4Completed1
DB01088Iloprost4Completed1
DB00331Metformin4Terminated1
DB00627Niacin4Completed1
DB00178Ramipril4Completed2
DB00178Ramipril4Recruiting1
DB00243Ranolazine4Withdrawn1
DB06228Rivaroxaban4Not Yet Recruiting1
DB00360Sapropterin4Not Yet Recruiting1
DB00641Simvastatin4Completed1
DB08816Ticagrelor4Terminated1
DB09030Vorapaxar4Recruiting1
DB06151AcetylcysteineNot AvailableRecruiting1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB00559BosentanNot AvailableCompleted1
DB00169CholecalciferolNot AvailableNot Yet Recruiting1
DB14046DichlorobenzeneNot AvailableRecruiting1
DB00975DipyridamoleNot AvailableTerminated1
DB09303EvolocumabNot AvailableRecruiting1
DB01088IloprostNot AvailableCompleted1
DB11629LaropiprantNot AvailableTerminated1
DB00722LisinoprilNot AvailableCompleted1
DB00627NiacinNot AvailableTerminated1
DB00497OxycodoneNot AvailableNot Yet Recruiting1
DB01229PaclitaxelNot AvailableCompleted1
DB01229PaclitaxelNot AvailableUnknown Status1
DB00230PregabalinNot AvailableNot Yet Recruiting1
DB00243RanolazineNot AvailableCompleted1
DB02709ResveratrolNot AvailableCompleted1
DB00020SargramostimNot AvailableActive Not Recruiting1
DB00641SimvastatinNot AvailableCompleted1
DB11815TilarginineNot AvailableCompleted1