Chronic Rhinosinusitis

Also known as: Sinusitis, Chronic / Chronic Sinusitis / Unspecified sinusitis (chronic) / Sinusitis chronic NOS / Chronic sinusitis, unspecified / Sinusitis (chronic) NOS / Chronic sinusitis NOS

DrugDrug NameDrug Description
DB00394Beclomethasone dipropionateBeclomethasone dipropionate is a prodrug of the free form, beclomethasone (beclomethasone-17-monopropionate). An anti-inflammatory, synthetic corticosteroid, it is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma and allergic rhinitis (seasonal and perennial). Beclometasone dipropionate is also being investigated for oral treatment in mild-to-moderate Crohn's disease of ileal or ileal-right colonic localisation and for "topical" use mild-to-moderate graft versus host disease. It is marketed under several brand names such as Qnasl (US) and Rivanase AQ (Canada).
DB08906Fluticasone furoateFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
DB00588Fluticasone propionateFluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990[L5962].
DrugDrug NameTargetType
DB00394Beclomethasone dipropionateCorticosteroid-binding globulincarrier
DB00394Beclomethasone dipropionateGlucocorticoid receptortarget
DB00394Beclomethasone dipropionateCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCytochrome P450 3A4enzyme
DB08906Fluticasone furoateCytochrome P450 3A4enzyme
DB08906Fluticasone furoateGlucocorticoid receptortarget
DB08906Fluticasone furoateMultidrug resistance protein 1transporter
DB08906Fluticasone furoateCytochrome P450 2C8enzyme
DB08906Fluticasone furoateSolute carrier organic anion transporter family member 1B1transporter
DB08906Fluticasone furoateCorticosteroid-binding globulincarrier
DB08906Fluticasone furoateMultidrug resistance protein 1carrier
DB08906Fluticasone furoateSolute carrier organic anion transporter family member 1B1carrier
DB08906Fluticasone furoateCytochrome P450 3A5enzyme
DB08906Fluticasone furoateCytochrome P450 3A7enzyme
DB08906Fluticasone furoateProgesterone receptortarget
DB08906Fluticasone furoateMineralocorticoid receptortarget
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateMultidrug resistance protein 1carrier
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DrugDrug NamePhaseStatusCount
DB00620Triamcinolone0Recruiting1
DB00254Doxycycline2Completed1
DB00187Esmolol2Completed1
DB00598Labetalol2Completed1
DB00764Mometasone2Completed1
DB00043Omalizumab2Completed1
DB00684Tobramycin2Completed1
DB11195Xylitol2Active Not Recruiting1
DB01222Budesonide2 / 3Not Yet Recruiting1
DB11121Chloroxylenol2 / 3Recruiting1
DB01167Itraconazole2 / 3Recruiting1
DB00620Triamcinolone2 / 3Recruiting1
DB11195Xylitol2 / 3Recruiting1
DB00681Amphotericin B3Completed1
DB01222Budesonide3Completed1
DB00003Dornase alfa3Completed1
DB01137Levofloxacin3Recruiting2
DB00305Mitomycin3Completed1
DB00764Mometasone3Completed1
DB14512Mometasone furoate3Completed1
DB00994Neomycin3Recruiting1
DB00043Omalizumab3Active Not Recruiting1
DB00043Omalizumab3Completed2
DB00635Prednisone3Recruiting1
DB00207Azithromycin4Completed1
DB00907Cocaine4Unknown Status1
DB01234Dexamethasone4Unknown Status1
DB00633Dexmedetomidine4Completed1
DB00668Epinephrine4Unknown Status1
DB01175Escitalopram4Terminated1
DB00959Methylprednisolone4Completed1
DB00410Mupirocin4Completed1
DB00043Omalizumab4Withdrawn1
DB00635Prednisone4Active Not Recruiting1
DB00818Propofol4Completed1
DB00899Remifentanil4Completed1
DB09153Sodium chloride4Unknown Status1
DB00316AcetaminophenNot AvailableCompleted1
DB00626BacitracinNot AvailableWithdrawn1
DB01222BudesonideNot AvailableCompleted1
DB01222BudesonideNot AvailableTerminated1
DB11121ChloroxylenolNot AvailableCompleted1
DB00169CholecalciferolNot AvailableWithdrawn1
DB01211ClarithromycinNot AvailableCompleted1
DB00153ErgocalciferolNot AvailableWithdrawn1
DB00588Fluticasone propionateNot AvailableCompleted1
DB00588Fluticasone propionateNot AvailableRecruiting2
DB00635PrednisoneNot AvailableCompleted1
DB00635PrednisoneNot AvailableRecruiting1
DB00818PropofolNot AvailableTerminated1
DB00899RemifentanilNot AvailableTerminated1
DB01236SevofluraneNot AvailableTerminated1
DB09153Sodium chlorideNot AvailableCompleted1
DB00302Tranexamic acidNot AvailableWithdrawn1
DB11094Vitamin DNot AvailableWithdrawn1
DB11195XylitolNot AvailableCompleted1