Hodgkins Disease (HD)

Also known as: Hodgkin's disease / Hodgkins Disease / Disease, Hodgkin / Hodgkin Disease / Disease, Hodgkins / Hodgkin's disease NOS / Hodgkin's granuloma / Hodgkin's paragranuloma / Hodgkin's sarcoma / Hodgkin's disease, unspecified type / Hodgins / Hodgkin lymphoma / Lymphomas Hodgkin's disease / Hodgkin's lymphoma / Lymphogranulomatosis

Drug	Drug Name	Drug Description
DB00291	Chlorambucil	A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
DB00888	Mechlorethamine	A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. [PubChem] The FDA granted marketing approval for the orphan drug Valchlor (mechlorethamine) gel on August 23, 2013 for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) in patients who have received prior skin-directed therapy. Each tube of Valchlor contains 0.016% of mechlorethamine which is equivalent to 0.02% mechlorethamine HCL.

Drug	Drug Name	Target	Type
DB00291	Chlorambucil	DNA	target
DB00291	Chlorambucil	Glutathione S-transferase P	enzyme
DB00291	Chlorambucil	Solute carrier organic anion transporter family member 1A2	transporter
DB00888	Mechlorethamine	DNA	target

Drug	Drug Name	Phase	Status	Count
DB12565	Abexinostat	1	Completed	2
DB00928	Azacitidine	1	Completed	1
DB00928	Azacitidine	1	Recruiting	1
DB00290	Bleomycin	1	Completed	1
DB08870	Brentuximab vedotin	1	Completed	4
DB08870	Brentuximab vedotin	1	Terminated	1
DB08889	Carfilzomib	1	Completed	1
DB01188	Ciclopirox	1	Completed	1
DB00631	Clofarabine	1	Active Not Recruiting	1
DB00531	Cyclophosphamide	1	Completed	1
DB00531	Cyclophosphamide	1	Recruiting	2
DB00987	Cytarabine	1	Completed	1
DB00851	Dacarbazine	1	Completed	1
DB01234	Dexamethasone	1	Completed	2
DB01234	Dexamethasone	1	Recruiting	1
DB00997	Doxorubicin	1	Completed	1
DB00773	Etoposide	1	Completed	1
DB01073	Fludarabine	1	Recruiting	2
DB00441	Gemcitabine	1	Completed	1
DB00441	Gemcitabine	1	Recruiting	1
DB00441	Gemcitabine	1	Terminated	1
DB00762	Irinotecan	1	Completed	1
DB01026	Ketoconazole	1	Completed	1
DB00480	Lenalidomide	1	Active Not Recruiting	1
DB11899	MK-8776	1	Completed	1
DB00683	Midazolam	1	Completed	1
DB02701	Nicotinamide	1	Completed	1
DB00526	Oxaliplatin	1	Recruiting	1
DB01229	Paclitaxel	1	Terminated	1
DB06603	Panobinostat	1	Completed	1
DB00019	Pegfilgrastim	1	Recruiting	1
DB09037	Pembrolizumab	1	Recruiting	1
DB01045	Rifampicin	1	Completed	1
DB06176	Romidepsin	1	Recruiting	1
DB00020	Sargramostim	1	Completed	1
DB00570	Vinblastine	1	Completed	1
DB00541	Vincristine	1	Completed	1
DB02546	Vorinostat	1	Completed	1
DB12565	Abexinostat	1 / 2	Completed	1
DB06769	Bendamustine	1 / 2	Completed	1
DB08870	Brentuximab vedotin	1 / 2	Active Not Recruiting	1
DB08870	Brentuximab vedotin	1 / 2	Completed	1
DB08870	Brentuximab vedotin	1 / 2	Recruiting	1
DB01008	Busulfan	1 / 2	Completed	1
DB08889	Carfilzomib	1 / 2	Recruiting	1
DB00531	Cyclophosphamide	1 / 2	Completed	1
DB00851	Dacarbazine	1 / 2	Recruiting	1
DB00997	Doxorubicin	1 / 2	Completed	1
DB00997	Doxorubicin	1 / 2	Recruiting	1
DB00773	Etoposide	1 / 2	Active Not Recruiting	1
DB00773	Etoposide	1 / 2	Completed	1
DB00099	Filgrastim	1 / 2	Completed	1
DB01073	Fludarabine	1 / 2	Completed	1
DB00441	Gemcitabine	1 / 2	Completed	1
DB01181	Ifosfamide	1 / 2	Active Not Recruiting	1
DB09037	Pembrolizumab	1 / 2	Not Yet Recruiting	1
DB06809	Plerixafor	1 / 2	Completed	2
DB00635	Prednisone	1 / 2	Completed	2
DB00073	Rituximab	1 / 2	Completed	1
DB05471	SGN-30	1 / 2	Completed	1
DB09325	Sodium fluoride	1 / 2	Active Not Recruiting	1
DB02891	Tricyclazole	1 / 2	Active Not Recruiting	1
DB00570	Vinblastine	1 / 2	Completed	1
DB00570	Vinblastine	1 / 2	Recruiting	1
DB02546	Vorinostat	1 / 2	Completed	1
DB00316	Acetaminophen	2	Completed	1
DB06151	Acetylcysteine	2	Completed	1
DB00173	Adenine	2	Active Not Recruiting	1
DB00087	Alemtuzumab	2	Completed	1
DB00087	Alemtuzumab	2	Terminated	1
DB00087	Alemtuzumab	2	Withdrawn	1
DB01143	Amifostine	2	Completed	1
DB11720	Angiotensin 1-7	2	Active Not Recruiting	1
DB00098	Antithymocyte immunoglobulin (rabbit)	2	Completed	2
DB00098	Antithymocyte immunoglobulin (rabbit)	2	Terminated	1
DB00074	Basiliximab	2	Completed	1
DB06769	Bendamustine	2	Completed	1
DB06769	Bendamustine	2	Recruiting	2
DB00290	Bleomycin	2	Active Not Recruiting	1
DB00290	Bleomycin	2	Completed	3
DB00290	Bleomycin	2	Terminated	1
DB00290	Bleomycin	2	Unknown Status	1
DB00188	Bortezomib	2	Completed	1
DB00188	Bortezomib	2	Terminated	1
DB08870	Brentuximab vedotin	2	Active Not Recruiting	1
DB08870	Brentuximab vedotin	2	Completed	3
DB08870	Brentuximab vedotin	2	Recruiting	3
DB11970	Burixafor	2	Completed	1
DB01008	Busulfan	2	Terminated	2
DB00262	Carmustine	2	Completed	2
DB00262	Carmustine	2	Terminated	1
DB00515	Cisplatin	2	Active Not Recruiting	1
DB00631	Clofarabine	2	Terminated	1
DB00531	Cyclophosphamide	2	Active Not Recruiting	1
DB00531	Cyclophosphamide	2	Completed	5
DB00531	Cyclophosphamide	2	Recruiting	1
DB00531	Cyclophosphamide	2	Terminated	2
DB00091	Cyclosporine	2	Completed	2
DB00091	Cyclosporine	2	Terminated	1
DB00987	Cytarabine	2	Active Not Recruiting	1
DB00987	Cytarabine	2	Completed	2
DB00987	Cytarabine	2	Terminated	1
DB00851	Dacarbazine	2	Active Not Recruiting	1
DB00851	Dacarbazine	2	Completed	1
DB00851	Dacarbazine	2	Recruiting	2
DB00851	Dacarbazine	2	Unknown Status	1
DB01234	Dexamethasone	2	Active Not Recruiting	1
DB01234	Dexamethasone	2	Terminated	1
DB01075	Diphenhydramine	2	Completed	1
DB00997	Doxorubicin	2	Active Not Recruiting	2
DB00997	Doxorubicin	2	Completed	3
DB00997	Doxorubicin	2	Recruiting	1
DB00997	Doxorubicin	2	Terminated	1
DB00997	Doxorubicin	2	Unknown Status	1
DB00773	Etoposide	2	Active Not Recruiting	1
DB00773	Etoposide	2	Completed	4
DB00773	Etoposide	2	Terminated	2
DB01590	Everolimus	2	Active Not Recruiting	1
DB00099	Filgrastim	2	Completed	3
DB01073	Fludarabine	2	Completed	3
DB01073	Fludarabine	2	Terminated	2
DB00441	Gemcitabine	2	Completed	5
DB00441	Gemcitabine	2	Terminated	1
DB00741	Hydrocortisone	2	Completed	1
DB01181	Ifosfamide	2	Completed	2
DB05550	Iratumumab	2	Completed	1
DB00125	L-Arginine	2	Terminated	1
DB00128	L-Aspartic Acid	2	Active Not Recruiting	1
DB00172	L-Proline	2	Active Not Recruiting	1
DB00480	Lenalidomide	2	Completed	2
DB00650	Leucovorin	2	Completed	1
DB00007	Leuprolide	2	Terminated	2
DB01042	Melphalan	2	Completed	4
DB01042	Melphalan	2	Terminated	2
DB05914	Mesenchymal Stem Cells	2	Recruiting	1
DB00563	Methotrexate	2	Completed	2
DB00959	Methylprednisolone	2	Completed	1
DB00688	Mycophenolate mofetil	2	Completed	3
DB00688	Mycophenolate mofetil	2	Terminated	1
DB09035	Nivolumab	2	Active Not Recruiting	1
DB09035	Nivolumab	2	Recruiting	2
DB06650	Ofatumumab	2	Completed	1
DB05829	Parathyroid hormone	2	Terminated	1
DB00019	Pegfilgrastim	2	Completed	1
DB00552	Pentostatin	2	Completed	1
DB00552	Pentostatin	2	Terminated	1
DB06809	Plerixafor	2	Completed	6
DB06809	Plerixafor	2	Terminated	1
DB00635	Prednisone	2	Active Not Recruiting	1
DB00635	Prednisone	2	Completed	2
DB00635	Prednisone	2	Terminated	1
DB01168	Procarbazine	2	Completed	1
DB00073	Rituximab	2	Active Not Recruiting	1
DB00073	Rituximab	2	Completed	1
DB00020	Sargramostim	2	Completed	2
DB00877	Sirolimus	2	Completed	3
DB00864	Tacrolimus	2	Completed	5
DB06285	Teriparatide	2	Terminated	1
DB01041	Thalidomide	2	Terminated	1
DB04572	Thiotepa	2	Terminated	1
DB00352	Tioguanine	2	Completed	1
DB00570	Vinblastine	2	Active Not Recruiting	1
DB00570	Vinblastine	2	Completed	3
DB00570	Vinblastine	2	Recruiting	1
DB00570	Vinblastine	2	Terminated	1
DB00570	Vinblastine	2	Unknown Status	1
DB00541	Vincristine	2	Active Not Recruiting	1
DB00541	Vincristine	2	Completed	2
DB00541	Vincristine	2	Terminated	1
DB00361	Vinorelbine	2	Completed	4
DB00361	Vinorelbine	2	Terminated	1
DB13144	Lenograstim	2 / 3	Completed	1
DB00290	Bleomycin	3	Completed	1
DB08870	Brentuximab vedotin	3	Active Not Recruiting	1
DB08870	Brentuximab vedotin	3	Recruiting	1
DB11121	Chloroxylenol	3	Active Not Recruiting	1
DB00851	Dacarbazine	3	Completed	1
DB00997	Doxorubicin	3	Completed	1
DB00016	Erythropoietin	3	Completed	1
DB00099	Filgrastim	3	Completed	1
DB00563	Methotrexate	3	Completed	1
DB00563	Methotrexate	3	Recruiting	1
DB00218	Moxifloxacin	3	Completed	1
DB00688	Mycophenolate mofetil	3	Recruiting	1
DB09035	Nivolumab	3	Recruiting	1
DB00552	Pentostatin	3	Completed	1
DB00864	Tacrolimus	3	Recruiting	1
DB00570	Vinblastine	3	Completed	1
DB00098	Antithymocyte immunoglobulin (rabbit)	Not Available	Completed	1
DB00074	Basiliximab	Not Available	Terminated	1
DB08870	Brentuximab vedotin	Not Available	Available	1
DB01008	Busulfan	Not Available	Completed	1
DB01008	Busulfan	Not Available	Suspended	1
DB00262	Carmustine	Not Available	Active Not Recruiting	1
DB00531	Cyclophosphamide	Not Available	Suspended	1
DB00531	Cyclophosphamide	Not Available	Terminated	1
DB00091	Cyclosporine	Not Available	Terminated	1
DB00987	Cytarabine	Not Available	Active Not Recruiting	1
DB00773	Etoposide	Not Available	Active Not Recruiting	1
DB01073	Fludarabine	Not Available	Completed	2
DB01073	Fludarabine	Not Available	Terminated	1
DB01042	Melphalan	Not Available	Active Not Recruiting	1
DB01042	Melphalan	Not Available	Completed	2
DB00688	Mycophenolate mofetil	Not Available	Terminated	1
DB06809	Plerixafor	Not Available	No Longer Available	1
DB00073	Rituximab	Not Available	Active Not Recruiting	1
DB00073	Rituximab	Not Available	Completed	1
DB00675	Tamoxifen	Not Available	Completed	1
DB06825	Triptorelin	Not Available	Completed	1