Showing BioInteractions for Fluciclovine (18F) (DB13146)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Neutral amino acid transporter B(0) binder | ||
| 1 | Neutral amino acid transporter B(0) substrates | L-Glutamine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Y+L amino acid transporter 1 binder | ||
| 1 | Y+L amino acid transporter 1 substrates | Agmatine, L-Glutamine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Cationic amino acid transporter 3 binder | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Glutamate (NMDA) receptor inhibitor | ||
| 1 | Glutamate (NMDA) receptor antagonists | Acamprosate, Enflurane, Gavestinel, Memantine |
| 2 | Glutamate (NMDA) receptor blockers | Magnesium carbonate |
| 3 | Glutamate (NMDA) receptor ligands | Aripiprazole, Magnesium acetate tetrahydrate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Glutamate receptor 1 inhibitor | ||
| 1 | Glutamate receptor 1 antagonists | Butabarbital, Desflurane, Isoflurane, Methoxyflurane, Perampanel, Sevoflurane |
| 2 | Glutamate receptor 1 inhibitors | Lamotrigine |
| 3 | Glutamate receptor 1 modulators | Tianeptine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Glutamate receptor 2 inhibitor | ||
| 1 | Glutamate receptor 2 antagonists | Amobarbital, Aprobarbital, Barbital, Butabarbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Phenobarbital, Primidone, Quinidine barbiturate, Secobarbital, Talbutal, Thiopental |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Glutamate receptor 3 inhibitor | ||
| 1 | Glutamate receptor 3 potentiators | Lithium cation |
| 2 | Glutamate receptor 3 antagonists | Butabarbital |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Glutamate receptor 4 inhibitor | ||
| 1 | Glutamate receptor 4 antagonists | Butabarbital |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Fluciclovine (18F) is a Multidrug resistance-associated protein 4 substrate | ||
| 1 | Multidrug resistance-associated protein 4 substrates | Adefovir dipivoxil, Alprostadil, Atorvastatin, Cefazolin, Cyclic adenosine monophosphate, Dinoprostone, Fluorouracil, Gadoxetic acid, Glutathione, Hydrochlorothiazide, Lamivudine, Mercaptopurine, Methotrexate, Nateglinide, Oseltamivir, Prasterone, Raloxifene, Rosuvastatin, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Zidovudine |
| 2 | Multidrug resistance-associated protein 4 inhibitors | Celecoxib, Cholic Acid, Conjugated estrogens, Cyclic adenosine monophosphate, Diclofenac, Dipyridamole, Flurbiprofen, Folic acid, Ibuprofen, Indomethacin, Ketoprofen, Methotrexate, Probenecid, Promethazine, Remdesivir, Rofecoxib, Rucaparib, Sildenafil, Sorafenib, Sulfinpyrazone, Sunitinib, Taurocholic acid, Tioguanine, Ursodeoxycholic acid, Verapamil |
| 3 | Multidrug resistance-associated protein 4 binders | Meloxicam |