Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
DrugDrug NameDrug Description
DB00114Pyridoxal phosphateA vitamin available in many formulations to correct vitamin B6 deficiency.
DB00147PyridoxalPyridoxal is one of the natural forms available of vitamin B6, therefore, it is used for nutritional supplementation and for treating dietary shortage or imbalances.
DB00165PyridoxineA vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy.
DB00184NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
DB00208TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
DB00213PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
DB00224IndinavirA protease inhibitor used to treat HIV infection.
DB00235MilrinoneAn inotropic vasodilator agent used to treat acute, decompensated heart failure.
DB00238NevirapineA non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
DB00270IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
DB00280DisopyramideA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB00366DoxylamineAn antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.
DB00381AmlodipineA calcium channel blocker used to treat hypertension and angina.
DB00393NimodipineA calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
DB00398SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
DB00401NisoldipineA calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
DB00402EszopicloneA sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.
DB00405DexbrompheniramineAn antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.
DB00427TriprolidineA sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep.
DB00448LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00528LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
DB00545PyridostigmineA cholinesterase inhibitor used to treat myasthenia gravis.
DB00609EthionamideA second line antitubercular agent used to treat tuberculosis when other treatments have failed.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB00627NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
DB00656TrazodoneA serotonin uptake inhibitor used to treat major depressive disorder.
DB00736EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DB00758ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB00792TripelennamineA histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.
DB00799TazaroteneAn acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
DB00809TropicamideA muscarinic receptor antagonist used to dilate the pupil.
DB00820TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
DB00835BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
DB00951IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
DB00969AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
DB01011MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
DB01023FelodipineA calcium channel blocker used to treat hypertension.
DB01025AmlexanoxUsed as a paste in the mouth to treat aphthous ulcers (canker sores).
DB01054NitrendipineFor the treatment of mild to moderate hypertension
DB01055MimosineMimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
DB01072AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB01115NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
DB01129RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB01188CiclopiroxA broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
DB01427AmrinoneA positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
DB01438PhenazopyridineA local anesthetic used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations that are a result of infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters.
DB01620PheniramineAn antihistamine used to treat allergic rhinitis and pruritus.
DB01656RoflumilastA selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis.
DB01796Quinolinic AcidA metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS....
DB019963-MethylpyridineNot Available
DB02567PD173955Not Available
DB02701NicotinamideAn ingredient found in a variety of cosmetic products.
DB04267Dipicolinic AcidNot Available
DB04365ArecolineAn alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the...
DB04552Niflumic acidUsed in the treatment of rheumatoid arthritis.
DB04631Atpenin A5Not Available
DB04818IproniazidFor the treatment of depression (originally intended to treat tuberculosis).
DB04819MethapyrileneMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
DB04820NialamideWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
DB04832ZimelidineFor the treatment of depression.
DB04951PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
DB05351DexlansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB05575MotesanibInvestigated for use/treatment in solid tumors.
DB05855RivaniclineInvestigated for use/treatment in ulcerative colitis.
DB06264TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
DB063314-O-DemethylpenclomedineInvestigated for use/treatment in solid tumors.
DB06334TucidinostatInvestigated for use/treatment in cancer/tumors (unspecified).
DB06397NicaravenInvestigated for use/treatment in cerebrovascular disease (unspecified).
DB06605ApixabanAn anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
DB06623FlupirtineInvestigated for use/treatment in fibromyalgia.
DB06637DalfampridineA potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS).
DB06691MepyramineAn antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.
DB06695Dabigatran etexilateAn anticoagulant used for the prevention of venous thromboembolic events or stroke in patients with recent elective hip or knee replacement surgery and atrial fibrillation.
DB06698BetahistineAn antivertigo agent used for the reduction of episodes of vertigo association with Ménière's disease.
DB06712NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
DB06796MangafodipirAn organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas.
DB08801DimetindeneIndicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except...
DB08826DeferiproneAn iron chelator used to treat patients with transfusional iron overload caused by thalassemia syndromes.
DB08840N-methylnicotinamideN-methylnicotinamide is an experimental drug with no approved indication.
DB08848GuvacineThere is no approved indication for guvacine.
DB08883PerampanelA non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
DB08911TrametinibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
DB08949Inositol nicotinateA vasodilator and source of niacin found in dietary supplements.
DB09092XanthinolA vasodilatory niacin found in diet supplements.
DB09178PhenaridinePhenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies,...
DB09194EtoperidoneEtoperidone has been studied for the treatment of depression , tremors in Parkinson, extrapyramidal symptoms and male impotence . It is not certain if it was ever approved and marketed...
DB09218ClonixinIndicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
DB09220NicorandilIndicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes.
DB09227BarnidipineIndicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina.
DB09229AranidipineAranidipine has been used for many years to treat angina pectoris and hypertension.
DB09230AzelnidipineFor the treatment of hypertension.
DB09231BenidipineBenidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris.
DB09232CilnidipineCilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been...
DB09234DarodipineDarodipine is a calcium channel blocker.
DB09235EfonidipineFor the treatment of hypertension.
DB09236LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .
DB09237LevamlodipineFor the treatment of hypertension and angina .
DB09238ManidipineFor the treatment of hypertension.
DB09239NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
DB09240NiludipineNiludipine is a calcium channel blocker.
DB09268Picosulfuric acidA stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults.
DB09280LumacaftorA protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene.
DB09285MorniflumateMorniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for...
DB09306MetralindoleInvestigated for the treatment of depression.
DB09366PropyliodoneRadiopaque medium usually in oil; used in bronchography.
DB09376LapyriumUsed as a surfactant, antistatic agent, and biocide in cosmetic products .
DB09488AcrivastineAn antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.
DB09555Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
DB11073CetylpyridiniumA compound used to reduce plaque and gingivitis, as well as whiten teeth.
DB11175Zinc picolinateZinc picolinate is a zinc salt of picolinic acid. It is available as OTC dietary supplements as a source of zinc to treat and prevent zinc deficiency. The absorption of...
DB11255Chromium picolinateChromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for...
DB11401EfrotomycinNot Annotated
DB11518FlunixinFlunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form....
DB11666BuparlisibBuparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others.
DB11673PyridoxaminePyridoxamine has been used in trials studying the treatment of Kidney Stones.
DB11694IlorasertibIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
DB11708PeficitinibPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
DB11730RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
DB11751CabotegravirCabotegravir has been investigated for the treatment of Acquired Immunodeficiency Syndrome.
DB11765PF-04991532PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.
DB11773BMS-903452BMS-903452 has been used in trials studying the treatment of Diabetes.
DB11863AlvelestatAlvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
DB11904FlumatinibFlumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic.
DB11964IlaprazoleIlaprazole has been investigated in Helicobacter Infections.
DB11974PF-04691502PF-04691502 has been used in trials studying the treatment of Cancer, Breast Neoplasms, Early Breast Cancer (Phase 2), and Advanced Breast Cancer (Phase 1b).
DB11977GolvatinibGolvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.
DB12001AbemaciclibA medication used to treat HR+ HER2- advanced or metastatic breast cancer.
DB12021DinaciclibDinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others.
DB12059JNJ-40411813JNJ-40411813 has been used in trials studying the treatment and basic science of Confusion, Schizophrenia, Perceptual Disorders, and Major Depressive Disorder.
DB12064BMS-777607BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
DB12154ItacitinibItacitinib has been used in trials studying the treatment of Melanoma, Carcinoma, Metastatic Cancer, Endometrial Cancer, and B-cell Malignancies, among others.
DB12241TAK-733TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.
DB12301DoravirineA non nucleoside reverse transcriptase inhibitor used to treat HIV infections.
DB12381MerestinibMerestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
DB12547LY-2886721LY2886721 has been used in trials studying the basic science of Alzheimer's Disease.
DB12585OndelopranOndelopran has been used in trials studying the treatment of Alcohol Dependence.
DB12667ProtionamideProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
DB12674LurbinectedinLurbinectedin has been used in trials studying the treatment of Solid Tumors, Breast Cancer, Ovarian Cancer, Metastatic Sarcoma, and Neuroendocrine Tumors, among others.
DB12756TAK-901TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
DB12792BoscalidBoscalid has been investigated for the treatment of OSDI, Glaucoma, Staining, Schirmers, and Disease Severity, among others.
DB12847PyroxamidePyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
DB12866PradigastatPradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).
DB12887TazemetostatTazemetostat has been used in trials studying the treatment of Rhabdoid Tumors, Synovial Sarcoma, Epithelioid sarcoma, INI1-negative Tumors, and Renal Medullary Carcinoma, among others.
DB12911NicoboxilA medication used to treat acute back pain.
DB12924OzenoxacinA quinolone antibiotic used to treat impetigo caused by susceptible bacteria.
DB12987PenclomedinePenclomedine has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
DB13001TinoridineTinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
DB13084PyritinolPyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
DB13135AGN-201904Agn 201904 has been used in trials studying the prevention of Peptic Ulcer.
DB13331PyrithyldioneNot Annotated
DB13407NifenazoneNot Annotated
DB13422NicofuranoseNot Annotated
DB13441NiceritrolNot Annotated
DB13454NicomorphineNot Annotated
DB13568DiodoneNot Annotated
DB13655NikethamideNot Annotated
DB13679DexchlorpheniramineDexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjuctive therapy for allergic and anaphylactic...
DB13687NiaprazineNot Annotated
DB13694DistigmineDistigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase...
DB13709CiclonicateNot Annotated
DB13740BemegrideNot Annotated
DB13744Piromidic acidNot Annotated
DB13745Fazadinium bromideNot Annotated
DB13750ObidoximeNot Annotated
DB13762DexrabeprazoleNot Annotated
DB13808MebhydrolinNot Annotated
DB13823Pipemidic acidNot Annotated
DB13874EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
DB13875HarmalineNot Annotated
DB13882Methyl nicotinateA methyl ester of niacin used to treat muscle and joint pain.
DB14068DexniguldipineNot Annotated
DB06518R-1487Investigated for use/treatment in rheumatoid arthritis.
DB019416-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic AcidNot Available
DB02209Pyridoxine phosphateNot Available
DB04145Nicotinyl alcoholA direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem]
DB07941PH-797804PH-797804 has been investigated for the treatment of Osteoarthritis.
DB11640AmifampridineA voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome.
DB12140DilmapimodDilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others.
DB14726DabigatranNot Annotated
DB14875AZD-4017AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
DB14904PimasertibPimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus).
DB14933Nicotinamide ribosideNicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis).
DB14982MiransertibMiransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma).
DB15273VS-4718VS-4718 is under investigation in clinical trial NCT02215629 (Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia).
DB15314ModimelanotideModimelanotide is under investigation in clinical trial NCT01897519 (A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High...
DB00214TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
DB00425ZolpidemA sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency.
DB00884Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
DB01628EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
DB06299HydronidoneInvestigated for use/treatment in liver disease.
DB08865CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
DB11710TrigonellamideTrigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers).
DB11982GDC-0623GDC-0623 has been used in trials studying the treatment of Solid Cancers.
DB12255VadadustatVadadustat has been used in trials studying the treatment of Anemia and Non-dialysis-dependent Chronic Kidney Disease.
DB12597ABL-001ABL001 has been used in trials studying the health services research of Chronic Myelogenous Leukemia and Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia.
DB13930UlixertinibUlixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity . It is currently in clinical trials for the treatment of a wide range of...
DB14785FenebrutinibFenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).
DB15033FlortaucipirFlortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
DB12978PexidartinibAn antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
DrugDrug NameTargetType
DB00114Pyridoxal phosphateCystathionine beta-synthasetarget
DB00114Pyridoxal phosphateAlanine--glyoxylate aminotransferase 2, mitochondrialtarget
DB00114Pyridoxal phosphateGlutamate decarboxylase 1target
DB00114Pyridoxal phosphateKynureninasetarget
DB00114Pyridoxal phosphateSerine hydroxymethyltransferase, cytosolictarget
DB00114Pyridoxal phosphateCysteine desulfurase, mitochondrialtarget
DB00114Pyridoxal phosphateAspartate aminotransferase, cytoplasmictarget
DB00114Pyridoxal phosphateOrnithine aminotransferase, mitochondrialtarget
DB00114Pyridoxal phosphateOrnithine decarboxylasetarget
DB00114Pyridoxal phosphateKynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget
DB00114Pyridoxal phosphate4-aminobutyrate aminotransferase, mitochondrialtarget
DB00114Pyridoxal phosphatePyridoxine-5'-phosphate oxidasetarget
DB00114Pyridoxal phosphateSphingosine-1-phosphate lyase 1target
DB00114Pyridoxal phosphateTyrosine aminotransferasetarget
DB00114Pyridoxal phosphateKynurenine--oxoglutarate transaminase 1target
DB00114Pyridoxal phosphateThreonine synthase-like 1target
DB00114Pyridoxal phosphateGlycogen phosphorylase, liver formtarget
DB00114Pyridoxal phosphateSerine palmitoyltransferase 2target
DB00114Pyridoxal phosphateCysteine sulfinic acid decarboxylasetarget
DB00114Pyridoxal phosphateHistidine decarboxylasetarget
DB00114Pyridoxal phosphateArginine decarboxylasetarget
DB00114Pyridoxal phosphateL-serine dehydratase/L-threonine deaminasetarget
DB00114Pyridoxal phosphate2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialtarget
DB00114Pyridoxal phosphateGlycine dehydrogenase [decarboxylating], mitochondrialtarget
DB00114Pyridoxal phosphateAlanine aminotransferase 1target
DB00114Pyridoxal phosphatePhosphoserine aminotransferasetarget
DB00114Pyridoxal phosphate5-aminolevulinate synthase, nonspecific, mitochondrialtarget
DB00114Pyridoxal phosphateSerine--pyruvate aminotransferasetarget
DB00114Pyridoxal phosphatePyridoxal phosphate phosphatasetarget
DB00114Pyridoxal phosphateSerine palmitoyltransferase 1target
DB00114Pyridoxal phosphateCystathionine gamma-lyasetarget
DB00114Pyridoxal phosphateBranched-chain-amino-acid aminotransferase, cytosolictarget
DB00114Pyridoxal phosphateBranched-chain-amino-acid aminotransferase, mitochondrialtarget
DB00114Pyridoxal phosphateProline synthase co-transcribed bacterial homolog proteintarget
DB00114Pyridoxal phosphateFormimidoyltransferase-cyclodeaminasetarget
DB00114Pyridoxal phosphateAspartate aminotransferase, mitochondrialtarget
DB00114Pyridoxal phosphateGlycogen phosphorylase, brain formtarget
DB00114Pyridoxal phosphateGlycogen phosphorylase, muscle formtarget
DB00114Pyridoxal phosphateAromatic-L-amino-acid decarboxylasetarget
DB00114Pyridoxal phosphateAspartate aminotransferasetarget
DB00114Pyridoxal phosphateSerine hydroxymethyltransferasetarget
DB00114Pyridoxal phosphateSelenocysteine lyase varianttarget
DB00114Pyridoxal phosphatePhosphorylasetarget
DB00114Pyridoxal phosphateOrnithine aminotransferase varianttarget
DB00114Pyridoxal phosphate5-aminolevulinate synthasetarget
DB00114Pyridoxal phosphateGlutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)target
DB00114Pyridoxal phosphateDDC proteintarget
DB00114Pyridoxal phosphatePyridoxal-dependent decarboxylase domain-containing protein 1target
DB00114Pyridoxal phosphateKynurenine--oxoglutarate transaminase 3target
DB00114Pyridoxal phosphateGlutamate decarboxylase-like protein 1target
DB00114Pyridoxal phosphateSelenocysteine lyasetarget
DB00114Pyridoxal phosphateImmunoglobulin superfamily member 10target
DB00114Pyridoxal phosphate5-phosphohydroxy-L-lysine phospho-lyasetarget
DB00114Pyridoxal phosphateGlutamate decarboxylase 1 (Brain, 67kDa)target
DB00114Pyridoxal phosphateSerine hydroxymethyltransferase, mitochondrialtarget
DB00114Pyridoxal phosphate5-aminolevulinate synthase, erythroid-specific, mitochondrialtarget
DB00114Pyridoxal phosphateAlanine aminotransferase 2target
DB00114Pyridoxal phosphateMolybdenum cofactor sulfurasetarget
DB00114Pyridoxal phosphateSerine dehydratase-liketarget
DB00114Pyridoxal phosphateHepatic peroxysomal alanine:glyoxylate aminotransferasetarget
DB00114Pyridoxal phosphateSerine racemasetarget
DB00114Pyridoxal phosphateO-phosphoseryl-tRNA(Sec) selenium transferasetarget
DB00114Pyridoxal phosphateSerine palmitoyltransferase 3target
DB00114Pyridoxal phosphateGlutamic acid decarboxylasetarget
DB00114Pyridoxal phosphateAlanine-glyoxylate aminotransferase homologtarget
DB00147PyridoxalPyridoxal kinasetarget
DB00165PyridoxinePyridoxal kinasetarget
DB00165PyridoxineCytochrome P450 1A1enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-2target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-2target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-7target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-10target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-9target
DB00184NicotineCytochrome P450 2A6enzyme
DB00184NicotineCytochrome P450 2E1enzyme
DB00184NicotineCytochrome P450 2A13enzyme
DB00184NicotineCytochrome P450 2B6enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit beta-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-3target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-5target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-6target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-3target
DB00184NicotineSolute carrier family 22 member 2transporter
DB00184NicotineSolute carrier family 22 member 1transporter
DB00184NicotineSolute carrier family 22 member 3transporter
DB00184NicotineSolute carrier family 22 member 5transporter
DB00184NicotineSolute carrier family 22 member 4transporter
DB00184NicotineCytochrome P450 1A1enzyme
DB00184NicotineCytochrome P450 1A2enzyme
DB00184NicotineCytochrome P450 2C19enzyme
DB00184NicotineCytochrome P450 2C8enzyme
DB00184NicotineCytochrome P450 2C9enzyme
DB00184NicotineCytochrome P450 2D6enzyme
DB00184NicotineCytochrome P450 3A4enzyme
DB00184NicotineAmine oxidase [flavin-containing] Aenzyme
DB00184NicotineAmine oxidase [flavin-containing] Benzyme
DB00184NicotineCytochrome P450 19A1target
DB00184NicotineCholine O-acetyltransferasetarget
DB00208TiclopidineP2Y purinoceptor 12target
DB00208TiclopidineCytochrome P450 2C19enzyme
DB00208TiclopidineCytochrome P450 2B6enzyme
DB00208TiclopidineCytochrome P450 2C9enzyme
DB00208TiclopidineCytochrome P450 2D6enzyme
DB00208TiclopidineMyeloperoxidaseenzyme
DB00208TiclopidineCytochrome P450 1A2enzyme
DB00208TiclopidineCytochrome P450 2C8enzyme
DB00208TiclopidineCytochrome P450 2E1enzyme
DB00213PantoprazolePotassium-transporting ATPase alpha chain 1target
DB00213PantoprazoleCytochrome P450 2C19enzyme
DB00213PantoprazoleCytochrome P450 3A4enzyme
DB00213PantoprazoleP-glycoprotein 1transporter
DB00213PantoprazoleATP-binding cassette sub-family G member 2transporter
DB00213PantoprazoleSolute carrier family 22 member 8transporter
DB00213PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00224IndinavirHuman immunodeficiency virus type 1 proteasetarget
DB00224IndinavirCytochrome P450 3A4enzyme
DB00224IndinavirCytochrome P450 3A5enzyme
DB00224IndinavirCytochrome P450 3A7enzyme
DB00224IndinavirP-glycoprotein 1transporter
DB00224IndinavirSolute carrier family 22 member 1transporter
DB00224IndinavirMultidrug resistance-associated protein 1transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1A2transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1B1transporter
DB00224IndinavirCanalicular multispecific organic anion transporter 1transporter
DB00224IndinavirCytochrome P450 2D6enzyme
DB00224IndinavirUDP-glucuronosyltransferase 1-1enzyme
DB00224IndinavirSolute carrier organic anion transporter family member 2B1transporter
DB00224IndinavirBile salt export pumptransporter
DB00235MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00238NevirapineCytochrome P450 3A4enzyme
DB00238NevirapineCytochrome P450 2B6enzyme
DB00238NevirapineCytochrome P450 3A5enzyme
DB00238NevirapineCytochrome P450 2C9enzyme
DB00238NevirapineCytochrome P450 2A6enzyme
DB00238NevirapineCytochrome P450 2D6enzyme
DB00238NevirapineReverse transcriptase/RNaseHtarget
DB00238NevirapineSerum albumincarrier
DB00238NevirapineCytochrome P450 1A2enzyme
DB00238NevirapineSolute carrier family 22 member 1transporter
DB00238NevirapineCytochrome P450 3A7enzyme
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00270IsradipineCytochrome P450 3A4enzyme
DB00270IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00270IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00270IsradipineBile salt export pumptransporter
DB00280DisopyramideSodium channel protein type 5 subunit alphatarget
DB00280DisopyramideAlpha-1-acid glycoprotein 1carrier
DB00280DisopyramideCytochrome P450 3A4enzyme
DB00280DisopyramideMuscarinic acetylcholine receptor M1target
DB00280DisopyramideMuscarinic acetylcholine receptor M2target
DB00280DisopyramideMuscarinic acetylcholine receptor M3target
DB00280DisopyramidePotassium voltage-gated channel subfamily D member 2target
DB00280DisopyramidePotassium voltage-gated channel subfamily D member 3target
DB00280DisopyramideSolute carrier family 22 member 2transporter
DB00280DisopyramideSolute carrier family 22 member 1transporter
DB00280DisopyramidePotassium voltage-gated channel subfamily H member 2target
DB00280DisopyramideAlpha-1-acid glycoprotein 2target
DB00280DisopyramideCytochrome P450 1A2enzyme
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00366DoxylamineHistamine H1 receptortarget
DB00366DoxylamineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineCYP2B proteinenzyme
DB00366DoxylamineNuclear receptor subfamily 1 group I member 3target
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineP-glycoprotein 1transporter
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB00381AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00381AmlodipineVoltage-dependent N-type calcium channeltarget
DB00393NimodipineCytochrome P450 3A4enzyme
DB00393NimodipineMineralocorticoid receptortarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
DB00393NimodipineAryl hydrocarbon receptortarget
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibP-glycoprotein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB00401NisoldipineCytochrome P450 3A4enzyme
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00401NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00401NisoldipineCytochrome P450 3A5enzyme
DB00401NisoldipineCytochrome P450 3A7enzyme
DB00401NisoldipineP-glycoprotein 1transporter
DB00402EszopicloneCytochrome P450 3A4enzyme
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-1target
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-2target
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-3target
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-5target
DB00402EszopicloneCytochrome P450 2C8enzyme
DB00402EszopicloneGABA-A receptor (anion channel)target
DB00405DexbrompheniramineHistamine H1 receptortarget
DB00427TriprolidineHistamine H1 receptortarget
DB00448LansoprazolePotassium-transporting ATPase alpha chain 1target
DB00448LansoprazoleCytochrome P450 2C19enzyme
DB00448LansoprazoleCytochrome P450 2C9enzyme
DB00448LansoprazoleCytochrome P450 3A4enzyme
DB00448LansoprazoleP-glycoprotein 1transporter
DB00448LansoprazoleATP-binding cassette sub-family G member 2transporter
DB00448LansoprazoleCytochrome P450 1A1enzyme
DB00448LansoprazoleCytochrome P450 1B1enzyme
DB00448LansoprazoleCytochrome P450 2C18enzyme
DB00448LansoprazoleCytochrome P450 2C8enzyme
DB00448LansoprazoleCytochrome P450 2D6enzyme
DB00448LansoprazoleMicrotubule-associated protein tautarget
DB00448LansoprazoleSolute carrier family 22 member 8transporter
DB00448LansoprazoleSolute carrier family 22 member 1transporter
DB00448LansoprazoleSolute carrier family 22 member 2transporter
DB00448LansoprazoleSolute carrier family 22 member 3transporter
DB00528LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
DB00528LercanidipineCytochrome P450 3A4enzyme
DB00528LercanidipineCytochrome P450 3A5enzyme
DB00528LercanidipineCytochrome P450 3A7enzyme
DB00528LercanidipineCytochrome P450 2D6enzyme
DB00545PyridostigmineAcetylcholinesterasetarget
DB00545PyridostigmineCholinesterasetarget
DB00545PyridostigmineSerum albumintarget
DB00609EthionamideCatalase-peroxidasetarget
DB00609EthionamideEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB00627NiacinHydroxycarboxylic acid receptor 2target
DB00627NiacinNicotinamide N-methyltransferasetarget
DB00627NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
DB00627NiacinHydroxycarboxylic acid receptor 3target
DB00627NiacinSolute carrier family 22 member 5transporter
DB00627NiacinSolute carrier organic anion transporter family member 2B1transporter
DB00627NiacinMonocarboxylate transporter 1transporter
DB00627NiacinCytochrome P450 2D6enzyme
DB00627NiacinSodium-coupled monocarboxylate transporter 1transporter
DB00627NiacinMonocarboxylate transporter 4transporter
DB00627NiacinThyroxine-binding globulincarrier
DB00627NiacinCytochrome P450 3A4enzyme
DB00627NiacinCytochrome P450 2E1enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Atarget
DB00656TrazodoneSodium-dependent serotonin transportertarget
DB00656TrazodoneAlpha-1A adrenergic receptortarget
DB00656TrazodoneAlpha-2A adrenergic receptortarget
DB00656TrazodoneHistamine H1 receptortarget
DB00656Trazodone5-hydroxytryptamine receptor 1Atarget
DB00656TrazodoneCytochrome P450 2D6enzyme
DB00656TrazodoneCytochrome P450 3A4enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Ctarget
DB00656TrazodoneCytochrome P450 3A5enzyme
DB00656TrazodoneCytochrome P450 3A7enzyme
DB00656TrazodoneP-glycoprotein 1transporter
DB00656Trazodone5-hydroxytryptamine receptor 1Ctarget
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00736EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazoleP-glycoprotein 1transporter
DB00736EsomeprazoleSolute carrier family 22 member 8transporter
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP-glycoprotein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB00792TripelennamineHistamine H1 receptortarget
DB00792TripelennamineCytochrome P450 2D6enzyme
DB00799TazaroteneRetinoic acid receptor alphatarget
DB00799TazaroteneRetinoic acid receptor RXR-betatarget
DB00799TazaroteneRetinoic acid receptor gammatarget
DB00799TazaroteneRetinoic acid receptor betatarget
DB00799TazaroteneCytochrome P450 2C8enzyme
DB00809TropicamideMuscarinic acetylcholine receptor M4target
DB00809TropicamideMuscarinic acetylcholine receptor M1target
DB00809TropicamideMuscarinic acetylcholine receptor M2target
DB00809TropicamideMuscarinic acetylcholine receptor M3target
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB00820TadalafilCytochrome P450 3A5enzyme
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB00951IsoniazidCatalase-peroxidasetarget
DB00951IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB00951IsoniazidCytochrome P450 2E1enzyme
DB00951IsoniazidCytochrome P450 1A2enzyme
DB00951IsoniazidCytochrome P450 2C9enzyme
DB00951IsoniazidCytochrome P450 2D6enzyme
DB00951IsoniazidCytochrome P450 2C19enzyme
DB00951IsoniazidCytochrome P450 3A4enzyme
DB00951IsoniazidArylamine N-acetyltransferase 2enzyme
DB00951IsoniazidArylamine N-acetyltransferaseenzyme
DB00951IsoniazidCytochrome P450 2A6enzyme
DB00951IsoniazidCytochrome P450 2C8enzyme
DB00951IsoniazidCytochrome P450 2C8target
DB00951IsoniazidCytochrome P450 1A2target
DB00951IsoniazidCytochrome P450 3A4target
DB00951IsoniazidCytochrome P450 2C19target
DB00951IsoniazidDihydrofolate reductasetarget
DB00951IsoniazidSerum albumincarrier
DB00969Alosetron5-hydroxytryptamine receptor 3Atarget
DB00969AlosetronCytochrome P450 1A2enzyme
DB00969AlosetronCytochrome P450 2C9enzyme
DB00969AlosetronCytochrome P450 3A4enzyme
DB00969AlosetronCytochrome P450 2E1enzyme
DB01011MetyraponeCamphor 5-monooxygenasetarget
DB01011MetyraponeCytochrome P450 11B2, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2A6enzyme
DB01011MetyraponeCytochrome P450 3A4enzyme
DB01011MetyraponeCanalicular multispecific organic anion transporter 2transporter
DB01011MetyraponeCytochrome P450 11B1, mitochondrialtarget
DB01011MetyraponeCytochrome P450 11B1, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2E1enzyme
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01023FelodipineCalmodulintarget
DB01023FelodipineCytochrome P450 3A4enzyme
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01023FelodipineCytochrome P450 2C8enzyme
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01023FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01023FelodipineTroponin C, skeletal muscletarget
DB01023FelodipineTroponin C, slow skeletal and cardiac musclestarget
DB01023FelodipineMineralocorticoid receptortarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01023FelodipineCytochrome P450 3A5enzyme
DB01023FelodipineCytochrome P450 3A7enzyme
DB01023FelodipineP-glycoprotein 1transporter
DB01023FelodipineCytochrome P450 2C9enzyme
DB01023FelodipineCytochrome P450 2D6enzyme
DB01023FelodipineBile salt export pumptransporter
DB01025AmlexanoxInterleukin-3target
DB01025AmlexanoxProtein S100-A12target
DB01025AmlexanoxProtein S100-A13target
DB01025AmlexanoxFibroblast growth factor 1target
DB01054NitrendipineVoltage-dependent calcium channel gamma-1 subunittarget
DB01054NitrendipineCytochrome P450 3A4enzyme
DB01054NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01054NitrendipineCytochrome P450 3A5enzyme
DB01054NitrendipineCytochrome P450 3A7enzyme
DB01054NitrendipineP-glycoprotein 1transporter
DB01054NitrendipineBile salt export pumptransporter
DB01055MimosineSerine hydroxymethyltransferase, cytosolictarget
DB01055MimosineC-C motif chemokine 2target
DB01055MimosineTyrosinasetarget
DB01072AtazanavirHuman immunodeficiency virus type 1 proteasetarget
DB01072AtazanavirCytochrome P450 3A4enzyme
DB01072AtazanavirCytochrome P450 2C9enzyme
DB01072AtazanavirP-glycoprotein 1transporter
DB01072AtazanavirMultidrug resistance-associated protein 1transporter
DB01072AtazanavirSerum albumincarrier
DB01072AtazanavirUDP-glucuronosyltransferase 1-1enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 1B1transporter
DB01072AtazanavirSolute carrier organic anion transporter family member 1B3transporter
DB01072AtazanavirCytochrome P450 2C8enzyme
DB01072AtazanavirBile salt export pumptransporter
DB01072Atazanaviralpha1-acid glycoproteincarrier
DB01072AtazanavirCytochrome P450 1A2enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 2B1transporter
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB01115NifedipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily A member 1target
DB01115NifedipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineP-glycoprotein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB01188CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
DB01427AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01427AmrinoneTumor necrosis factortarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
DB01438PhenazopyridineSodium channel protein type 1 subunit alphatarget
DB01438PhenazopyridineGroup A nerve fiberstarget
DB01620PheniramineHistamine H1 receptortarget
DB01620PheniramineNuclear receptor subfamily 1 group I member 3target
DB01620PheniramineHistamine H4 receptortarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01656RoflumilastCytochrome P450 3A4enzyme
DB01796Quinolinic AcidNicotinate-nucleotide pyrophosphorylase [carboxylating]target
DB01796Quinolinic AcidNicotinate-nucleotide pyrophosphorylase [carboxylating]target
DB019963-MethylpyridineCollagenase 3target
DB019963-MethylpyridineStromelysin-1target
DB02567PD173955Tyrosine-protein kinase transforming protein Abltarget
DB02701NicotinamideNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
DB02701NicotinamideADP-ribosyl cyclase 2target
DB02701NicotinamideExotoxin Atarget
DB02701NicotinamideL-lactate dehydrogenase A chaintarget
DB02701NicotinamidePoly [ADP-ribose] polymerase 1target
DB02701NicotinamideCytochrome P450 2D6enzyme
DB02701NicotinamideCytochrome P450 2E1enzyme
DB02701NicotinamideCytochrome P450 3A4enzyme
DB04267Dipicolinic Acid4-hydroxy-tetrahydrodipicolinate reductasetarget
DB04267Dipicolinic Acid4-hydroxy-tetrahydrodipicolinate reductasetarget
DB04365ArecolineMuscarinic acetylcholine receptor M1target
DB04365ArecolineMuscarinic acetylcholine receptor M3target
DB04552Niflumic acidPhospholipase A2target
DB04552Niflumic acidChloride channel protein ClC-Katarget
DB04552Niflumic acidMonocarboxylate transporter 2transporter
DB04552Niflumic acidMonocarboxylate transporter 1transporter
DB04552Niflumic acidProstaglandin G/H synthase 2target
DB04552Niflumic acidProstaglandin G/H synthase 1target
DB04552Niflumic acidCytosolic phospholipase A2target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
DB04631Atpenin A5Succinate dehydrogenase flavoprotein subunittarget
DB04631Atpenin A5Succinate dehydrogenase iron-sulfur subunittarget
DB04631Atpenin A5Succinate dehydrogenase cytochrome b556 subunittarget
DB04631Atpenin A5Succinate dehydrogenase hydrophobic membrane anchor subunittarget
DB04818IproniazidAmine oxidase [flavin-containing] Benzyme
DB04818IproniazidCytochrome P450 2D6enzyme
DB04818IproniazidCytochrome P450 2C9enzyme
DB04818IproniazidAmine oxidase [flavin-containing] Aenzyme
DB04820NialamideAmine oxidase [flavin-containing] Btarget
DB04820NialamideAmine oxidase [flavin-containing] Atarget
DB04820NialamideCatechol O-methyltransferasetarget
DB04832ZimelidineSodium-dependent serotonin transportertarget
DB04832ZimelidineP-glycoprotein 1transporter
DB04832ZimelidineAmine oxidase [flavin-containing] Btarget
DB04832ZimelidineAmine oxidase [flavin-containing] Atarget
DB04832ZimelidineCytochrome P450 3A4enzyme
DB04951PirfenidoneFurintarget
DB04951PirfenidoneCytochrome P450 1A2enzyme
DB05351DexlansoprazolePotassium-transporting ATPase alpha chain 1target
DB05351DexlansoprazoleCytochrome P450 2C19enzyme
DB05351DexlansoprazoleCytochrome P450 3A4enzyme
DB05351DexlansoprazolePotassium-transporting ATPase subunit betatarget
DB05351DexlansoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB05855RivaniclineNeuronal acetylcholine receptor subunit beta-2target
DB05855RivaniclineInterleukin-8target
DB06264TolperisoneCytochrome P450 1A2enzyme
DB063314-O-DemethylpenclomedineDNAtarget
DB06605ApixabanCoagulation factor Xtarget
DB06605ApixabanCytochrome P450 3A4enzyme
DB06605ApixabanCytochrome P450 1A2enzyme
DB06605ApixabanCytochrome P450 2C8enzyme
DB06605ApixabanCytochrome P450 2C9enzyme
DB06605ApixabanCytochrome P450 2C19enzyme
DB06605ApixabanCytochrome P450 2J2enzyme
DB06605ApixabanP-glycoprotein 1transporter
DB06605ApixabanATP-binding cassette sub-family G member 2transporter
DB06605ApixabanCytochrome P450 3A5enzyme
DB06623FlupirtineAlpha-2A adrenergic receptortarget
DB06637DalfampridineCytochrome P450 2E1enzyme
DB06637DalfampridinePotassium voltage-gated channel subfamily D member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily D member 3target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 1target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 4target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 3target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 5target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 6target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 7target
DB06637DalfampridinePotassium voltage-gated channel subfamily A member 10target
DB06637DalfampridinePotassium voltage-gated channel subfamily B member 1target
DB06637DalfampridinePotassium voltage-gated channel subfamily B member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily C member 1target
DB06637DalfampridinePotassium voltage-gated channel subfamily C member 2target
DB06637DalfampridinePotassium voltage-gated channel subfamily C member 3target
DB06637DalfampridinePotassium voltage-gated channel subfamily D member 1target
DB06637DalfampridineSolute carrier family 22 member 2transporter
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB06695Dabigatran etexilateProthrombintarget
DB06695Dabigatran etexilateP-glycoprotein 1transporter
DB06695Dabigatran etexilateLiver carboxylesterase 1enzyme
DB06695Dabigatran etexilateCocaine esteraseenzyme
DB06695Dabigatran etexilateUDP-glucuronosyltransferase 1-9enzyme
DB06695Dabigatran etexilateUDP-glucuronosyltransferase 2B7enzyme
DB06695Dabigatran etexilateUDP-glucuronosyltransferase 2B15enzyme
DB06695Dabigatran etexilateRibosyldihydronicotinamide dehydrogenase [quinone]enzyme
DB06698BetahistineHistamine H1 receptortarget
DB06698BetahistineHistamine H3 receptortarget
DB06712NilvadipineCytochrome P450 3A4enzyme
DB06712NilvadipineCytochrome P450 2A6enzyme
DB06712NilvadipineCytochrome P450 2C19enzyme
DB06712NilvadipineCytochrome P450 2C8enzyme
DB06712NilvadipineCytochrome P450 2E1enzyme
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB06712NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB06796MangafodipirAlpha-2-macroglobulincarrier
DB06796MangafodipirSerum albumincarrier
DB06796MangafodipirSuperoxide dismutase [Mn], mitochondrialenzyme
DB06796MangafodipirNatural resistance-associated macrophage protein 2transporter
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB08826DeferiproneUDP-glucuronosyltransferase 1-6enzyme
DB08840N-methylnicotinamideSolute carrier family 22 member 2transporter
DB08840N-methylnicotinamideMultidrug and toxin extrusion protein 1transporter
DB08840N-methylnicotinamideMultidrug and toxin extrusion protein 2transporter
DB08840N-methylnicotinamideAldehyde oxidaseenzyme
DB08848GuvacineSodium- and chloride-dependent GABA transporter 2target
DB08848GuvacineSodium- and chloride-dependent GABA transporter 1target
DB08848GuvacineSodium- and chloride-dependent GABA transporter 3target
DB08848GuvacineSodium- and chloride-dependent betaine transportertarget
DB08883PerampanelGlutamate receptor 1target
DB08883PerampanelCytochrome P450 3A4enzyme
DB08883PerampanelCytochrome P450 3A5enzyme
DB08883PerampanelCytochrome P450 1A2enzyme
DB08883PerampanelCytochrome P450 2B6enzyme
DB08911TrametinibCytochrome P450 2C8enzyme
DB08911TrametinibCytochrome P450 3A4enzyme
DB08911TrametinibDual specificity mitogen-activated protein kinase kinase 1target
DB08911TrametinibDual specificity mitogen-activated protein kinase kinase 2target
DB08949Inositol nicotinateSodium-coupled monocarboxylate transporter 1transporter
DB08949Inositol nicotinateATP synthase subunit beta, mitochondrialenzyme
DB08949Inositol nicotinateHydroxycarboxylic acid receptor 3target
DB08949Inositol nicotinateHydroxycarboxylic acid receptor 2target
DB08949Inositol nicotinateDiacylglycerol O-acyltransferase 2enzyme
DB09092Xanthinol60S ribosomal protein L3target
DB09092XanthinolNAD(P) transhydrogenase, mitochondrialtarget
DB09092XanthinolGlyceraldehyde-3-phosphate dehydrogenasetarget
DB09092XanthinolIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
DB09092Xanthinol2-oxoglutarate dehydrogenase, mitochondrialtarget
DB09092XanthinolMalate dehydrogenase, mitochondrialtarget
DB09194EtoperidoneAlpha-1 adrenergic receptorstarget
DB09194EtoperidoneAlpha-2 adrenergic receptorstarget
DB09194EtoperidoneDopamine D2 receptortarget
DB09194EtoperidoneMuscarinic acetylcholine receptortarget
DB09194Etoperidone5-hydroxytryptamine receptor 2Atarget
DB09194EtoperidoneSodium-dependent serotonin transportertransporter
DB09194EtoperidoneSodium-dependent noradrenaline transportertransporter
DB09194EtoperidoneSodium-dependent dopamine transportertransporter
DB09194Etoperidone5-hydroxytryptamine receptor 2Ctarget
DB09220NicorandilATP-binding cassette sub-family C member 9target
DB09227BarnidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09227BarnidipineCytochrome P450 3A4enzyme
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB09229AranidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB09229AranidipineAlpha adrenergic receptortarget
DB09229AranidipineSerum albumincarrier
DB09229AranidipineAlpha-1-acid glycoprotein 1carrier
DB09229AranidipineCytochrome P450 3A4enzyme
DB09230AzelnidipineCytochrome P450 3A4enzyme
DB09230AzelnidipineVoltage-dependent L-type calcium channel subunit beta-1target
DB09231BenidipineVoltage-dependent L-type calcium channeltarget
DB09231BenidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB09231BenidipineVoltage-dependent T-type calcium channeltarget
DB09231BenidipineCytochrome P450 3A4enzyme
DB09231BenidipineCytochrome P450 3A5enzyme
DB09232CilnidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB09232CilnidipineVoltage-dependent L-type calcium channeltarget
DB09232CilnidipineCytochrome P450 3A4enzyme
DB09234DarodipineCytochrome P450 3A4enzyme
DB09235EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB09235EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09235EfonidipineCytochrome P450 3A4enzyme
DB09236LacidipineCytochrome P450 3A4enzyme
DB09236LacidipineSerum albumincarrier
DB09236LacidipineAlpha-1-acid glycoprotein 1carrier
DB09236LacidipineVoltage-dependent L-type calcium channeltarget
DB09237LevamlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09237LevamlodipineCytochrome P450 3A4enzyme
DB09237LevamlodipineNitric oxide synthase, endothelialtarget
DB09237LevamlodipineNitric oxide synthase, inducibletarget
DB09237LevamlodipineNitric oxide synthase, inducibleenzyme
DB09237LevamlodipineNitric oxide synthase, endothelialenzyme
DB09238ManidipineVoltage-dependent L-type calcium channeltarget
DB09238ManidipineVoltage-dependent T-type calcium channeltarget
DB09238ManidipineCytochrome P450 2C9enzyme
DB09238ManidipineCytochrome P450 2D6enzyme
DB09238ManidipineCytochrome P450 1A1enzyme
DB09238ManidipineCytochrome P450 2B6enzyme
DB09238ManidipineCytochrome P450 2C19enzyme
DB09238ManidipineCytochrome P450 3A4enzyme
DB09239NiguldipineAlpha-1A adrenergic receptortarget
DB09239NiguldipineCytochrome P450 3A4enzyme
DB09240NiludipineCytochrome P450 3A4enzyme
DB09268Picosulfuric acidArylsulfate sulfotransferaseenzyme
DB09280LumacaftorCytochrome P450 2B6enzyme
DB09280LumacaftorCytochrome P450 2C8enzyme
DB09280LumacaftorCytochrome P450 2C9enzyme
DB09280LumacaftorCytochrome P450 2C19enzyme
DB09280LumacaftorSerum albumincarrier
DB09280LumacaftorCystic fibrosis transmembrane conductance regulatortarget
DB09280LumacaftorCytochrome P450 3A4enzyme
DB09280LumacaftorP-glycoprotein 1transporter
DB09285MorniflumateArachidonate 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumateArachidonate 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1-9enzyme
DB09488AcrivastineHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
DB09555Dexchlorpheniramine maleateCytochrome P450 3A4enzyme
DB11730RibociclibCyclin-dependent kinase 4target
DB11730RibociclibCyclin-dependent kinase 6target
DB11730RibociclibCytochrome P450 3A4enzyme
DB11751CabotegravirSolute carrier family 22 member 6transporter
DB11751CabotegravirSolute carrier family 22 member 8transporter
DB12001AbemaciclibMultidrug and toxin extrusion protein 1transporter
DB12001AbemaciclibMultidrug and toxin extrusion protein 2transporter
DB12001AbemaciclibCyclin-dependent kinase 4target
DB12001AbemaciclibCyclin-dependent kinase 6target
DB12001AbemaciclibSerum albumincarrier
DB12001Abemaciclibalpha1-acid glycoproteincarrier
DB12001AbemaciclibCytochrome P450 3A4enzyme
DB12001AbemaciclibP-glycoprotein 1transporter
DB12001AbemaciclibATP-binding cassette sub-family G member 2transporter
DB12001AbemaciclibSolute carrier family 22 member 2transporter
DB12001AbemaciclibCytochrome P450 1A2enzyme
DB12001AbemaciclibCytochrome P450 2B6enzyme
DB12001AbemaciclibCytochrome P450 2C8enzyme
DB12001AbemaciclibCytochrome P450 2C9enzyme
DB12001AbemaciclibCytochrome P450 2D6enzyme
DB12301DoravirineCytochrome P450 3A4enzyme
DB12301DoravirineCytochrome P450 3A5enzyme
DB12301DoravirineReverse transcriptase/RNaseHtarget
DB12866PradigastatSolute carrier family 22 member 8transporter
DB12887TazemetostatHistone-lysine N-methyltransferase EZH2target
DB12924OzenoxacinDNA gyrase subunit Atarget
DB12924OzenoxacinDNA topoisomerase 4 subunit Atarget
DB13679DexchlorpheniramineCytochrome P450 2D6enzyme
DB13762DexrabeprazoleCytochrome P450 2C19enzyme
DB13823Pipemidic acidCytochrome P450 1A2enzyme
DB13874EnasidenibCytochrome P450 1A2enzyme
DB13874EnasidenibCytochrome P450 2B6enzyme
DB13874EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
DB13874EnasidenibCytochrome P450 2C8enzyme
DB13874EnasidenibCytochrome P450 2C9enzyme
DB13874EnasidenibCytochrome P450 2C19enzyme
DB13874EnasidenibCytochrome P450 2D6enzyme
DB13874EnasidenibCytochrome P450 3A4enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-1enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-3enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-4enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 1-9enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 2B7enzyme
DB13874EnasidenibUDP-glucuronosyltransferase 2B15enzyme
DB13874EnasidenibP-glycoprotein 1transporter
DB13874EnasidenibATP-binding cassette sub-family G member 2transporter
DB13874EnasidenibSolute carrier family 22 member 6transporter
DB13874EnasidenibSolute carrier organic anion transporter family member 1B1transporter
DB13874EnasidenibSolute carrier family 22 member 2transporter
DB13874EnasidenibSolute carrier organic anion transporter family member 1B3transporter
DB13874EnasidenibSolute carrier family 22 member 8transporter
DB13875HarmalineHistamine N-methyltransferasetarget
DB14068DexniguldipineP-glycoprotein 1target
DB14068DexniguldipineCytochrome P450 3A4enzyme
DB06518R-1487Mitogen-activated protein kinase 14target
DB019416-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic AcidRetinoic acid receptor RXR-betatarget
DB02209Pyridoxine phosphatePyridoxine 5'-phosphate synthasetarget
DB02209Pyridoxine phosphateOrnithine decarboxylasetarget
DB02209Pyridoxine phosphatePyridoxine-5'-phosphate oxidaseenzyme
DB02209Pyridoxine phosphatePyridoxine 5'-phosphate phosphataseenzyme
DB07941PH-797804Mitogen-activated protein kinase 14target
DB11640AmifampridineArylamine N-acetyltransferase 1enzyme
DB11640AmifampridineArylamine N-acetyltransferase 2enzyme
DB11640AmifampridinePotassium voltage-gated channel subfamily A member 1target
DB12140DilmapimodTumor necrosis factortarget
DB12140DilmapimodInterleukin-1 betatarget
DB12140DilmapimodInterleukin-6target
DB00214TorasemideSolute carrier family 12 member 1target
DB00214TorasemideCytochrome P450 2C8enzyme
DB00214TorasemideCytochrome P450 2C9enzyme
DB00214TorasemideSolute carrier organic anion transporter family member 1B1transporter
DB00214TorasemideSolute carrier family 12 member 2target
DB00214TorasemideSerum albumincarrier
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
DB00425ZolpidemCytochrome P450 3A4enzyme
DB00425ZolpidemCytochrome P450 1A2enzyme
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
DB00425ZolpidemCytochrome P450 2C9enzyme
DB00425ZolpidemCytochrome P450 2C19enzyme
DB00425ZolpidemCytochrome P450 2D6enzyme
DB00425ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
DB00884Risedronic acidFarnesyl pyrophosphate synthasetarget
DB00884Risedronic acidHydroxylapatitetarget
DB00884Risedronic acidProstaglandin G/H synthase 2enzyme
DB01628EtoricoxibProstaglandin G/H synthase 2target
DB01628EtoricoxibCytochrome P450 3A4enzyme
DB01628EtoricoxibCytochrome P450 2C9enzyme
DB01628EtoricoxibCytochrome P450 2D6enzyme
DB01628EtoricoxibCytochrome P450 1A2enzyme
DB01628EtoricoxibCytochrome P450 2C19enzyme
DB01628EtoricoxibCytochrome P450 2E1enzyme
DB08865CrizotinibCytochrome P450 3A4enzyme
DB08865CrizotinibCytochrome P450 3A5enzyme
DB08865CrizotinibP-glycoprotein 1transporter
DB08865CrizotinibALK tyrosine kinase receptortarget
DB08865CrizotinibHepatocyte growth factor receptortarget
DB08865CrizotinibCytochrome P450 2B6enzyme
DB08865CrizotinibCytochrome P450 3A Subfamilyenzyme
DB13930UlixertinibMitogen-activated protein kinase 3target
DB13930UlixertinibMitogen-activated protein kinase 1target
DB12978PexidartinibCytochrome P450 3A4enzyme
DB12978PexidartinibUDP-glucuronosyltransferase 1-4enzyme
DB12978PexidartinibMacrophage colony-stimulating factor 1 receptortarget
DB12978PexidartinibCytochrome P450 2B6enzyme
DB12978PexidartinibCytochrome P450 2C9enzyme
DB12978PexidartinibUDP-glucuronosyltransferase 1-1enzyme
DB12978PexidartinibMultidrug and toxin extrusion protein 1transporter
DB12978PexidartinibMultidrug and toxin extrusion protein 2transporter
DB12978PexidartinibSolute carrier organic anion transporter family member 1B1transporter
DB12978PexidartinibSolute carrier organic anion transporter family member 1B3transporter
DB12978PexidartinibSolute carrier organic anion transporter family member 2B1transporter
DB12978PexidartinibSerum albumincarrier
DB12978PexidartinibAlpha-1-acid glycoprotein 1carrier
DB12978PexidartinibMast/stem cell growth factor receptor Kittarget
DB12978PexidartinibReceptor-type tyrosine-protein kinase FLT3target
DB12978PexidartinibPlatelet-derived growth factor receptor betatarget