Tumors Metastatic to Brain

Also known as: Brain Tumor - Metastatic / Metastatic Brain Cancer / Brain Metastases / Metastases, Brain / Metastases to Brain / Metastatic Brain Tumor / Brain cancer metastatic / Metastatic Brain Tumors / Secondary malignant neoplasm of brain / Brain secondaries / Metastasis to brain / Metastases to central nervous system

DrugDrug NameDrug Description
DB00262CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
DB01206LomustineAn alkylating agent used as a part of chemotherapeutic regimens for the treatment of primary and metastatic brain tumors as well as refractory or relapsed Hodgkin's disease in addition to surgical and/or radiotherapeutic treatments.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB14644Methylprednisolone hemisuccinateA water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DrugDrug NameTargetType
DB00262CarmustineGlutathione reductase, mitochondrialtarget
DB00262CarmustineDNAtarget
DB00262CarmustineRNAtarget
DB01206LomustineDNAtarget
DB01206LomustineCytochrome P450 3A4enzyme
DB01206LomustineCytochrome P450 2D6enzyme
DB01206LomustineStathmin-4target
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier
DB14644Methylprednisolone hemisuccinateCytochrome P450 3A4enzyme
DB14644Methylprednisolone hemisuccinateCytochrome P450 3A5enzyme
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB09063Ceritinib0Active Not Recruiting1
DB14784Gancotamab0Withdrawn1
DB00072Trastuzumab0Withdrawn1
DB11851Bafetinib1Completed1
DB06769Bendamustine1Terminated1
DB00290Bleomycin1Terminated1
DB04849Cediranib1Terminated1
DB00987Cytarabine1Completed1
DB08912Dabrafenib1Recruiting1
DB11687E-62011Recruiting1
DB00530Erlotinib1Completed1
DB00773Etoposide1Completed1
DB15186GDC-00841Recruiting1
DB12091Gadolinium1Completed1
DB06186Ipilimumab1Completed1
DB01259Lapatinib1Completed2
DB09035Nivolumab1Recruiting1
DB11870RG-47331Terminated1
DB12060RRx-0011Active Not Recruiting1
DB04996Satraplatin1Completed1
DB00398Sorafenib1Active Not Recruiting2
DB00398Sorafenib1Completed1
DB01268Sunitinib1Active Not Recruiting1
DB00853Temozolomide1Completed2
DB00853Temozolomide1Terminated1
DB00072Trastuzumab1Completed1
DB00135Tyrosine1Completed1
DB00313Valproic acid1Completed1
DB00313Valproic acid1Terminated1
DB08881Vemurafenib1Withdrawn1
DB02546Vorinostat1Completed1
DB00112Bevacizumab1 / 2Withdrawn1
DB00958Carboplatin1 / 2Completed1
DB00997Doxorubicin1 / 2Completed1
DB00143Glutathione1 / 2Completed1
DB01016Glyburide1 / 2Recruiting1
DB14865Human interleukin-21 / 2Withdrawn1
DB11737Icotinib1 / 2Completed1
DB06186Ipilimumab1 / 2Recruiting1
DB06186Ipilimumab1 / 2Withdrawn1
DB09035Nivolumab1 / 2Recruiting1
DB01229Paclitaxel1 / 2Withdrawn1
DB09037Pembrolizumab1 / 2Recruiting1
DB00853Temozolomide1 / 2Completed1
DB00853Temozolomide1 / 2Withdrawn1
DB00072Trastuzumab1 / 2Completed1
DB150754-demethyl-4-cholesteryloxycarbonylpenclomedine2Not Yet Recruiting1
DB12001Abemaciclib2Completed1
DB08916Afatinib2Recruiting1
DB14930Alovudine F-182Completed1
DB00112Bevacizumab2Active Not Recruiting2
DB00112Bevacizumab2Completed1
DB00112Bevacizumab2Recruiting2
DB11967Binimetinib2Recruiting2
DB11666Buparlisib2Completed1
DB08875Cabozantinib2Active Not Recruiting1
DB14776Camrelizumab2Not Yet Recruiting1
DB14776Camrelizumab2Recruiting1
DB01101Capecitabine2Completed1
DB00958Carboplatin2Recruiting1
DB00262Carmustine2Completed1
DB00262Carmustine2Not Yet Recruiting1
DB00515Cisplatin2Active Not Recruiting1
DB00515Cisplatin2Completed2
DB00515Cisplatin2Recruiting2
DB05239Cobimetinib2Recruiting1
DB00987Cytarabine2Completed1
DB08912Dabrafenib2Active Not Recruiting1
DB01234Dexamethasone2Active Not Recruiting1
DB01234Dexamethasone2Not Yet Recruiting1
DB11714Durvalumab2Recruiting1
DB11718Encorafenib2Recruiting2
DB06423Endostatin2Unknown Status1
DB14860Ensartinib2Recruiting1
DB08871Eribulin2Active Not Recruiting1
DB00530Erlotinib2Completed1
DB00530Erlotinib2Unknown Status2
DB14951Etirinotecan pegol2Completed1
DB00773Etoposide2Active Not Recruiting1
DB00773Etoposide2Completed1
DB00947Fulvestrant2Not Yet Recruiting1
DB00317Gefitinib2Recruiting1
DB11737Icotinib2Recruiting1
DB11737Icotinib2Unknown Status1
DB05975Iniparib2Completed1
DB06186Ipilimumab2Active Not Recruiting3
DB06186Ipilimumab2Completed1
DB06186Ipilimumab2Recruiting1
DB00762Irinotecan2Completed2
DB01259Lapatinib2Completed2
DB01259Lapatinib2Not Yet Recruiting1
DB00678Losartan2Recruiting1
DB04967Lucanthone2Withdrawn1
DB00331Metformin2Not Yet Recruiting1
DB00563Methotrexate2Completed2
DB09035Nivolumab2Active Not Recruiting1
DB09035Nivolumab2Recruiting1
DB00904Ondansetron2Active Not Recruiting1
DB09330Osimertinib2Not Yet Recruiting1
DB09330Osimertinib2Recruiting1
DB06171Paclitaxel trevatide2Completed2
DB09073Palbociclib2Not Yet Recruiting1
DB09037Pembrolizumab2Completed1
DB09037Pembrolizumab2Recruiting1
DB00642Pemetrexed2Completed1
DB00642Pemetrexed2Not Yet Recruiting1
DB00642Pemetrexed2Recruiting3
DB12257Platinum2Completed1
DB14993Pyrotinib2Recruiting1
DB05920RTA 7442Terminated1
DB14765Rivoceranib2Not Yet Recruiting1
DB00641Simvastatin2Completed1
DB00853Temozolomide2Completed3
DB00853Temozolomide2Terminated1
DB00853Temozolomide2Unknown Status1
DB05007Tesevatinib2Completed1
DB11973Tesevatinib2Completed1
DB01041Thalidomide2Completed1
DB01030Topotecan2Unknown Status1
DB08911Trametinib2Active Not Recruiting1
DB00072Trastuzumab2Active Not Recruiting1
DB00072Trastuzumab2Completed2
DB00072Trastuzumab2Not Yet Recruiting1
DB14962Trastuzumab deruxtecan2Active Not Recruiting1
DB05773Trastuzumab emtansine2Recruiting1
DB08881Vemurafenib2Recruiting1
DB00361Vinorelbine2Recruiting1
DB13104X-3962Recruiting1
DB14795AZD-37592 / 3Recruiting1
DB00530Erlotinib2 / 3Recruiting1
DB13146Fluciclovine (18F)2 / 3Not Yet Recruiting1
DB00317Gefitinib2 / 3Recruiting2
DB14684Calcium polycarbophil3Not Yet Recruiting1
DB01101Capecitabine3Completed1
DB01101Capecitabine3Not Yet Recruiting1
DB08871Eribulin3Not Yet Recruiting1
DB00530Erlotinib3Terminated1
DB13146Fluciclovine (18F)3Not Yet Recruiting1
DB04106Fotemustine3Recruiting1
DB06703Gadobutrol3Completed1
DB00597Gadoteridol3Completed1
DB11737Icotinib3Recruiting1
DB06186Ipilimumab3Recruiting1
DB01259Lapatinib3Completed1
DB01043Memantine3Recruiting1
DB00563Methotrexate3Not Yet Recruiting1
DB09035Nivolumab3Recruiting1
DB09330Osimertinib3Not Yet Recruiting1
DB06171Paclitaxel trevatide3Not Yet Recruiting1
DB00853Temozolomide3Recruiting1
DB00853Temozolomide3Terminated1
DB01041Thalidomide3Completed1
DB00072Trastuzumab3Completed1
DB00112BevacizumabNot AvailableNot Yet Recruiting1
DB06186IpilimumabNot AvailableRecruiting1
DB00742MannitolNot AvailableNot Yet Recruiting1
DB09035NivolumabNot AvailableRecruiting1
DB09037PembrolizumabNot AvailableRecruiting1
DB00818PropofolNot AvailableCompleted1