Showing BioInteractions for Acepromazine (DB01614)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 6

	Interacting Group	Interacting Drugs
	Acepromazine is a Dopamine D2 receptor antagonist
1	Dopamine D2 receptor agonists	Amantadine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cariprazine, Dihydro-alpha-ergocryptine, Dopamine, Ergotamine, Ketamine, Lamotrigine, Levodopa, Lisuride, Memantine, Minaprine, Pergolide, Pramipexole, Quinagolide, Ropinirole, Rotigotine
2	Dopamine D2 receptor antagonists	Acetophenazine, Alizapride, Amisulpride, Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Bromopride, Buspirone, Carphenazine, Chlorpromazine, Chlorprothixene, Clozapine, Domperidone, Droperidol, Etoperidone, Flupentixol, Fluphenazine, Fluspirilene, Haloperidol, Iloperidone, JNJ-37822681, Loxapine, Lurasidone, Melperone, Memantine, Mesoridazine, Methotrimeprazine, Metoclopramide, Mianserin, Molindone, Nortriptyline, Olanzapine, Paliperidone, Perospirone, Perphenazine, Pimozide, Pipamperone, Pipotiazine, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Raclopride, Remoxipride, Risperidone, Sertindole, Sulpiride, Tetrahydropalmatine, Thiethylperazine, Thioproperazine, Thioridazine, Thiothixene, Trifluoperazine, Triflupromazine, YKP-1358, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
3	Dopamine D2 receptor partial agonists	Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Cariprazine, Ketamine, Lumateperone, Sarizotan
4	Dopamine D2 receptor inhibitors	Escitalopram, Lamotrigine, Tetrabenazine
5	Dopamine D2 receptor binders	Amphetamine, Desipramine, Imipramine, Maprotiline
6	Dopamine D2 receptor blockers	Tiapride

	Interacting Group	Interacting Drugs
	Acepromazine is a Dopamine D1 receptor antagonist
1	Dopamine D1 receptor antagonists	Amoxapine, Aripiprazole, Asenapine, Carphenazine, Chlorpromazine, Chlorprothixene, Clozapine, Flupentixol, Fluphenazine, Haloperidol, Iloperidone, Lisuride, Loxapine, Methotrimeprazine, Methylergometrine, Olanzapine, Paliperidone, Periciazine, Perphenazine, Pipamperone, Pipotiazine, Quetiapine, Risperidone, Tetrahydropalmatine, Thioproperazine, Thioridazine, Thiothixene, Triflupromazine, Ziprasidone, Zuclopenthixol
2	Dopamine D1 receptor agonists	Apomorphine, Bromocriptine, Cabergoline, Dopamine, Fenoldopam, Levodopa, Minaprine, Pergolide, Rotigotine
3	Dopamine D1 receptor partial agonists	Aripiprazole, Phenylpropanolamine
4	Dopamine D1 receptor ligands	Aripiprazole

	Interacting Group	Interacting Drugs
	Acepromazine is a 5-hydroxytryptamine receptor 2A antagonist
1	5-hydroxytryptamine receptor 2A antagonists	Amisulpride, Amitriptyline, Amoxapine, Amperozide, Aripiprazole, Aripiprazole lauroxil, Asenapine, Blonanserin, Brexpiprazole, Butriptyline, Cariprazine, Chlorpromazine, Chlorprothixene, Cinitapride, Clomipramine, Clozapine, Cyclobenzaprine, Cyproheptadine, Deramciclane, Desipramine, Dosulepin, Doxepin, Epinastine, Etoperidone, Flibanserin, Flupentixol, Fluspirilene, Iloperidone, Imipramine, Lorpiprazole, Loxapine, Lumateperone, Lurasidone, Mesoridazine, Methotrimeprazine, Methysergide, Mianserin, Minaprine, Mirtazapine, Molindone, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Pipotiazine, Pizotifen, Promazine, Propiomazine, Quetiapine, Risperidone, Sertindole, Tegaserod, Thioridazine, Thiothixene, Trazodone, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
2	5-hydroxytryptamine receptor 2A partial agonists	4-Bromo-2,5-dimethoxyphenethylamine, Aripiprazole
3	5-hydroxytryptamine receptor 2A agonists	2,5-Dimethoxy-4-ethylthioamphetamine, 5-methoxy-N,N-dimethyltryptamine, Apomorphine, Bromocriptine, Cabergoline, Cannabidiol, Cisapride, Ergotamine, Fenfluramine, Lisuride, Midomafetamine, MMDA, N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine, Paroxetine, Pergolide, Pipamperone, Trimipramine, Zolmitriptan
4	5-hydroxytryptamine receptor 2A inducers	Donepezil
5	5-hydroxytryptamine receptor 2A inverse agonists	Ketanserin, Perospirone, Pimavanserin, Ritanserin, Sarpogrelate
6	5-hydroxytryptamine receptor 2A binders	Maprotiline
7	5-hydroxytryptamine receptor 2A inhibitors	Escitalopram, Lamotrigine

	Interacting Group	Interacting Drugs
	Acepromazine is a 5-hydroxytryptamine receptor 1A antagonist
1	5-hydroxytryptamine receptor 1A partial agonists	Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Buspirone, Cariprazine, Perospirone, Quetiapine, Trazodone, Yohimbine
2	5-hydroxytryptamine receptor 1A agonists	5-methoxy-N,N-dimethyltryptamine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cannabidiol, Cariprazine, Cinitapride, Eletriptan, Ergotamine, Fenfluramine, Flibanserin, Lisuride, Lofexidine, Methysergide, Naluzotan, Naratriptan, Oxymetazoline, Pergolide, Pramipexole, Rotigotine, SEP-363856, Sumatriptan, Tetrahydrocannabivarin, Vilazodone, Vortioxetine, Ziprasidone, Zolmitriptan
3	5-hydroxytryptamine receptor 1A antagonists	Alprenolol, Alverine, Amoxapine, Asenapine, Chlorpromazine, Clozapine, Dosulepin, Doxepin, Iloperidone, Lurasidone, Molindone, Nefazodone, Nortriptyline, Paliperidone, Penbutolol, Pindolol, Pipotiazine, Pirlindole, Pizotifen, Quetiapine, Risperidone, Trazodone, Trimipramine
4	5-hydroxytryptamine receptor 1A inhibitors	Amitriptyline, Escitalopram, Tianeptine
5	5-hydroxytryptamine receptor 1A inducers	Amitriptyline
6	5-hydroxytryptamine receptor 1A binders	Desipramine, Dopamine, Loxapine
7	5-hydroxytryptamine receptor 1A activators	Imipramine
8	5-hydroxytryptamine receptor 1A blockers	Mianserin

	Interacting Group	Interacting Drugs
	Acepromazine is a Alpha-1A adrenergic receptor antagonist
1	Alpha-1A adrenergic receptor agonists	4-Methoxyamphetamine, Apraclonidine, Benzphetamine, Bromocriptine, Cirazoline, Clonidine, Dipivefrin, Droxidopa, Ephedrine, Epinephrine, Ergometrine, Isometheptene, Lofexidine, Metaraminol, Methoxamine, Midodrine, Naphazoline, Norepinephrine, Pergolide, Phendimetrazine, Phenylephrine, Pseudoephedrine, Racepinephrine, Tetryzoline, Xylometazoline
2	Alpha-1A adrenergic receptor antagonists	Alfuzosin, Amitriptyline, Amoxapine, Aripiprazole, Aripiprazole lauroxil, Asenapine, Bevantolol, Bromocriptine, Carvedilol, Chlorpromazine, Clozapine, Dapiprazole, Doxazosin, Doxepin, Dronedarone, Droperidol, Flupentixol, Iloperidone, Imipramine, Indoramin, Methotrimeprazine, Nefazodone, Nicardipine, Nicergoline, Niguldipine, Nortriptyline, Olanzapine, Paliperidone, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Promazine, Propiomazine, Propiverine, Quinidine, Risperidone, Silodosin, Tamsulosin, Terazosin, Thioproperazine, Thioridazine, Tolazoline, Trazodone, Trifluoperazine, Trimipramine, Verapamil, Ziprasidone, Zuclopenthixol
3	Alpha-1A adrenergic receptor partial agonists	Ergotamine, Oxymetazoline, Xylometazoline
4	Alpha-1A adrenergic receptor potentiators	Carvedilol
5	Alpha-1A adrenergic receptor inhibitors	Amitriptyline, Fenoldopam, Lamotrigine
6	Alpha-1A adrenergic receptor binders	Cabergoline, Loxapine

	Interacting Group	Interacting Drugs
	Acepromazine is a Alpha-1B adrenergic receptor antagonist
1	Alpha-1B adrenergic receptor antagonists	Alfuzosin, Amitriptyline, Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Bromocriptine, Carvedilol, Chlorpromazine, Clozapine, Dapiprazole, Dextroamphetamine, Doxepin, Dronedarone, Imipramine, Methotrimeprazine, Nicardipine, Nortriptyline, Olanzapine, Paliperidone, Periciazine, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Quinidine, Risperidone, Silodosin, Tamsulosin, Terazosin, Thioproperazine, Thioridazine, Trimipramine, Verapamil, Ziprasidone
2	Alpha-1B adrenergic receptor partial agonists	Cirazoline, Ergotamine, Modafinil
3	Alpha-1B adrenergic receptor agonists	Bromocriptine, Clonidine, Droxidopa, Epinephrine, Methoxamine, Midodrine, Norepinephrine, Oxymetazoline, Pergolide, Phendimetrazine, Phenylephrine, Racepinephrine, Xylometazoline
4	Alpha-1B adrenergic receptor binders	Cabergoline, Loxapine
5	Alpha-1B adrenergic receptor inhibitors	Fenoldopam