- Accession Number
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Drug Drug Description Indium In-111 satumomab pendetide For diagnosis of extrahepatic malignant cancers Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin infections and bacteremia due to Staphylococcus aureus. alpha-Linolenic acid A polyunsaturated omega-3 fatty acid found in many supplements. Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Calcifediol An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients. Ergocalciferol A vitamin found in many supplement products. Dihomo-gamma-linolenic acid For nutritional supplementation, also for treating dietary shortage or imbalance Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Lipoic acid For nutritional supplementation, also for treating dietary shortage or imbalance. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Gadodiamide A gadolinium-based contrast agent used for the visualization of lesions with vascularity during magnetic resonance imaging (MRI) scans. Calcium acetate A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression. Travoprost A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension. Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. Treprostinil A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol. Mupirocin An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Sodium tetradecyl sulfate An anionic surfactant used to treat varicose veins of the lower extremities. Montelukast A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. Aminocaproic acid An antifibrinolytic agent used to induce clotting postoperatively. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Linezolid An oxazolidinone antibiotic used to treat susceptible strains of multidrug resistant bacterial infections. Candoxatril Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor. Docosanol An antiviral used to treat orofacial herpes sores. Clofibrate A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. Dextropropoxyphene An opioid analgesic used to treat mild to moderate pain. Latanoprost An isopropyl ester prodrug used to treat increased intraocular pressure. Mycophenolate mofetil An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. Flurbiprofen An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Alprostadil A medication used to treat erectile dysfunction. Gadopentetic acid A gadolinium compound used as a contrast agent in MRIs. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Sodium lauryl sulfate An anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent. Progabide Indicated for the treatment of epilepsy. Benzylpenicilloyl polylysine A penicillin derivative used to determine penicillin allergies. Etacrynic acid A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Paricalcitol A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease. Dinoprostone A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers. Zaleplon A sedative used for short term treatment of insomnia in adults. Ethiodized oil A contrast agent used in imaging procedures. Oxaprozin An NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. Mycophenolic acid An immunosuppressant used to prevent organ transplant rejections. Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Dihydrotachysterol A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3. Atorvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Vigabatrin An irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years. Iloprost A synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). Fluvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Colistimethate An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. Phenacemide Used to control certain seizures in the treatment of epilepsy. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Dinoprost tromethamine Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities... Ridogrel Used as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction. Epoprostenol A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure. Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. Aluminium monostearate Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging... Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. Alfacalcidol A vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure. gamma-Hydroxybutyric acid Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. Tiaprofenic acid A nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis. Propyl acetate Not Available TU-514 Not Available Aminooxyacetic acid A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem] Cholesteryl Linoleate Not Available 4-Oxosebacic Acid Not Available Platelet Activating Factor Not Available Calcipotriol A topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. Prostaglandin B2 Not Available 12-Bromododecanoic Acid Not Available 4-(2-Thienyl)Butyric Acid Not Available Farnesol A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in... Isobutyric acid Not Available 2-Butanol Not Available Adenosine Phosphonoacetic Acid Not Available Fumagillin Not Available Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Acetamide Not Available Canaline Not Available Phosphonoacetic Acid A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem] 2-aminoisobutyric acid Not Available Ricinoleic Acid Not Available Bombykol Not Available Lauric acid Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily... Nitrilotriacetic acid Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.) Glycolic acid Not Available Acetic acid An antimicrobial agent used to treat susceptible infections of the external auditory canal. Stearic acid An ingredient found in topical products as a skin protectant. Lysophosphatidylglycerol Not Available N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. Sparfosic acid Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen... Tricosanoic acid Not Available Butyric Acid A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester. Capric acid Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include... Lanosterol Not Available Cyclohexanol Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem] 12-Hydroxydodecanoic Acid Not Available 2-Methylbutanoic Acid Not Available Isovaleric Acid Not Available Dihydrolipoic Acid Not Available Palmitic Acid A fatty used as a food additive and emollient or surfactant in cosmetics. L-2,4-diaminobutyric acid Not Available Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. Prostaglandin G2 A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] Dodecyl sulfate Not Available Coelenteramide Not Available 5-phenylpentanoic acid Not Available Heptane-1,2,3-Triol Not Available Indole-3-Glycerol Phosphate Not Available Valpromide Not Available Mdl-29951 Not Available L-2-amino-3-butynoic acid Not Available Oleic Acid A naturally occurring fatty acid with antibacterial properties added to a variety of drug products. Palmitoleic Acid Not Available Seocalcitol Not Available Phosphatidylethanolamine Not Available Alpha-Aminobutyric Acid Not Available Caprylic acid Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a... Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Arachidonic Acid An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides.... 4,7-Dioxosebacic Acid Not Available Choline alfoscerate A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes... 20-hydroxycholesterol Not Available 5-hydroxyvaleric acid Not Available Inecalcitol Investigated for use/treatment in prostate cancer, psoriasis and hyperparathyroidism. Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Tienilic acid For the treatment of hypertension. Dexloxiglumide For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD). Oleoyl-estrone For the treatment of obesity. Voglibose For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications. Becocalcidiol For topical treatment of psoriasis and psoriatic disorders. Lucinactant Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. Eritoran Investigated for use/treatment in sepsis and septicemia. Erdosteine Fro the treatment of chronic bronchitis in adults. AN-9 Investigated for use/treatment in liver cancer, lung cancer, melanoma, and leukemia (lymphoid). Asimadoline Investigated for use/treatment in irritable bowel syndrome (IBS). Rilapladib Investigated for use/treatment in atherosclerosis and cardiovascular disorders. Gemcabene Investigated for use/treatment in atherosclerosis, cardiovascular disorders, and hyperlipidemia. Aminocandin Investigated for use/treatment in fungal infections. Elafibranor Investigated for use/treatment in atherosclerosis and diabetes mellitus type 2. AM103 For the treatment of asthma and cardiovascular disease. Beraprost For the treatment of pulmonary hypertension. Fenoxaprop-ethyl Chronic angina and Coronary Artery Disease Caprospinol Alzheimer's Disease Tarenflurbil Investigated for use/treatment in alzheimer's disease and prostate cancer. Arundic acid Investigated for use/treatment in cerebral ischemia. C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. Emricasan Investigated for use/treatment in hepatitis (viral, C), liver disease, and transplantation (organ or tissue). ETC-588 Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases. Elacytarabine Investigated for use/treatment in leukemia (unspecified) and melanoma. Cobiprostone Investigated for use/treatment in cystic fibrosis. Bedoradrine Investigated for use/treatment in asthma and labor and delivery. Iodofiltic acid I-123 Investigated for use/treatment in cardiac ischemia. BL-1020 Investigated for use/treatment in schizophrenia and schizoaffective disorders. Varespladib methyl Investigated for use/treatment in atherosclerosis and coronary artery disease. DP-b99 Investigated for use/treatment in strokes and traumatic brain injuries. DP-VPA Investigated for use/treatment in bipolar disorders, epilepsy, and migraine and cluster headaches. AGI-1096 Investigated for use/treatment in transplant (rejection). KX-01 Investigated for use/treatment in cancer/tumors (unspecified). Indibulin Investigated for use/treatment in solid tumors. Elocalcitol Investigated for use/treatment in benign prostatic hyperplasia, urinary incontinence, prostate disorders, and infertility. Lacosamide An antiepileptic drug used to treat partial onset seizures in adults. Maxacalcitol Not Annotated Senicapoc Investigated for use/treatment in anemia (sickle cell) and asthma. Fiboflapon Investigated for use/treatment in inflammatory disorders (unspecified). Doxercalciferol A synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis. Avasimibe Investigated for use/treatment in peripheral vascular disease. E5531 Investigated for use/treatment in sepsis and septicemia. Remacemide Investigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease. Agomelatine Agomelatine is indicated to treat major depressive episodes in adults. Priralfinamide Investigated for use/treatment in pain (acute or chronic). Almorexant Investigated for use/treatment in sleep disorders and insomnia. Ethanolamine oleate A mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes. Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Zaltoprofen A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Bendamustine An antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Levopropoxyphene Levopropoxyphene was used as an antitussive. An antitussive is a medication often recommended for the treatment of cough and associated respiratory tract disorders. Its enantiomer, dextropropoxyphene, presents an analgesic effect. Mangafodipir An organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas. Monoctanoin Monoctanoin is used to dissolve cholesterol gallstones. Nepafenac An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Unoprostone A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. Sobetirome Not Available Sebacic acid Not Available ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Not Available 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid Metabolic product of biphenyl; from Pseudomonas putida. IDD594 Not Available 11-MERCAPTOUNDECANOIC ACID Not Available Myristic acid Not Available Efaproxiral Not Available Dichloroacetic acid Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms.... Tafluprost An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Leukotriene C4 The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates... Gabapentin enacarbil A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Gadoxetic acid A gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver. Icosapent ethyl An ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia. Arbaclofen Placarbil Investigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Gemeprost Indicated for the softening and dilatation of the cervix uteri prior to transcervical, intrauterine operative procedures in the first trimester of pregnancy or facilitating therapeutic termination of pregnancy in patients... Etofibrate Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations. Clinofibrate Clinofibrate is a fibrate drug sold and marketed in Japan. Beclamide Has been used in the management of epilepsy and epilepsy related behavioural disorders. It was used for generalised tonic-clonic seizures, and was not effective for absence seizures. More recently focus... Ciprofibrate Not Annotated Sodium oxybate A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Colfosceril palmitate A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Uridine triacetate A pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine. Piracetam Indicated in adult patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies . Limaprost Limaprost is used for the improvement of various ischemic symptoms such as ulcer, pain and feeling of coldness associated with thromboangiitis obliterans as well as improvement of subjective symptoms (pain... Iproclozide For the treatment of depression. Pivhydrazine For the treatment of depression. Caroxazone For the treatment of depression. Sacubitril A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Sodium acetate A compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Safflower oil No approved therapeutic indications. Cetyl alcohol No therapeutic indications in medicinal products. Indicated to be used as an indirect additive in food contact substances, or an ingredient in commercial or cosmetic products. Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Sodium glycerophosphate A medication used to treat hypophosphatemia. Cocoa butter Indicated for topical use in over-the-counter skin products for the treatment of skin dryness and reduction of striae gravidarum (stretch marks). Lanolin An ingredient used in skin care products to relieve irritation. Castor oil An ingredient used in a variety of natural health products. Undecylenic acid An antifungal used to treat tinea species infections. Turpentine A medication used to treat minor aches and pains of muscles and joints. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Trichloroacetate Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it... Calcium threonate No approved therapeutic indications. Sesame oil Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic... L-threonic acid Not Annotated Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Tea tree oil Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications. Octacosanol 1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. This high–molecular-weight organic compound is the main component of a natural product wax extracted... Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Glyceryl monostearate Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods. DL-dimyristoylphosphatidylcholine DL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication. DL-dimyristoylphosphatidylglycerol DL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications. Rice bran oil Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It... Cod liver oil An ingredient found in a variety of nutritional products. Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Clove oil Clove oil is primarily indicated in conditions like colic, flatulence, and toothache . Linseed oil Linseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic... Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Selexipag A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Chlorobutanol No approved therapeutic indications on its own. Fenprostalene Not Annotated Luprostiol Not Annotated Monensin Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds. Prostalene Analog of prostaglandin F2 alpha. Cloprostenol Not Annotated Fluprostenol Not Annotated Lesinurad A uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy. Cetalkonium An antiseptic used as a preservative or to treat certain topical infections. Beeswax Beeswax is also characterized by several therapeutic properties of great interest to us; it is thought to be particularly effective in healing bruises, inflammation and burns. Recently, the interest of... Latanoprostene bunod A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. Triheptanoin Triheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders. PF-06282999 Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects). Antineoplaston A10 Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others. Tanzisertib Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others. AZD-5672 Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis. VTP-194204 Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer. Arhalofenate Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia. Leukotriene D4 Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis. Etiracetam Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)). PF-00610355 PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others. Sutezolid Sutezolid has been used in trials studying the treatment of Tuberculosis. Varespladib Varespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome. Ingavirin Ingavirin has been used in trials studying the treatment of Influenza and Common Cold. Lomibuvir Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection. Atagabalin Atagabalin has been used in trials studying the treatment of Insomnia, Primary Insomnia, and Nonrestorative Sleep. Mapracorat Mapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis. Letermovir An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Orantinib Orantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others. Surotomycin Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... CPI-613 CPI-613 has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others. Figopitant Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers). Tricaprylin Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease. GSK-424887 Gsk424887 has been used in trials studying the basic science and treatment of Depressive Disorder and Anxiety Disorder. KRN-7000 KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients... AZD-5423 AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD). 9CUAB30 9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others. Siagoside Siagoside has been investigated for the treatment of Parkinson Disease. MBX-8025 MBX-8025 has been used in trials studying the treatment of Hyperlipidemia. Lifibrol Lifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia. Caprylic alcohol Caprylic alcohol has been used in trials studying the treatment of Essential Tremor. PD-217014 PD-217,014 has been used in trials studying the treatment of Pain and Irritable Bowel Syndrome. Clascoterone Clascoterone has been used in trials studying the treatment of Acne Vulgaris. Imiglitazar Imiglitazar has been used in trials studying the treatment of Diabetes Mellitus. MK-0686 MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic. Pentetreotide Pentetreotide has been used in trials studying the diagnostic of cushing syndrome. Taprenepag Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Salirasib Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. Sulprostone Sulprostone has been used in trials studying Abortion, Induced. Tributyrin Tributyrin has been used in trials studying the treatment of Prostate Cancer and Unspecified Adult Solid Tumor, Protocol Specific. Bindarit Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy. Lafutidine Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). Dinoprost A medication used to induce a second trimester abortion. CMX-2043 CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. MK-0752 Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer). Pradigastat Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD). Pivagabine Pivagabine has been used in trials studying the treatment of Stress and Anxiety. Leukotriene B4 Leukotriene B4 has been used in trials studying the treatment of HIV Infections. AQX-1125 AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome. MK-8245 MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus. Glyceryl Trioleate Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy. 1alpha-Hydroxyvitamin D5 1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity. Resolvin E1 Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers). Glycovir Glycovir has been used in trials studying the treatment of HIV Infections. Levomenol Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Omega-6 fatty acids There are no current pharmacotherapeutic products based on omega-6 fatty acids. Glyceryl 1-oleate Not Available Fentiazac Not Annotated Etofamide Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued . Alminoprofen Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances. Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Tiadenol Not Annotated Difenpiramide Not Annotated Simfibrate Not Annotated Prethcamide Not Annotated Mazaticol Not Annotated Phenibut Not Annotated Iodine (131I) norcholesterol Not Annotated Cyclobutyrol Not Annotated Clefamide Not Annotated Pranoprofen Not Annotated Mifamurtide A muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection. Lorcainide Not Annotated Tacalcitol Not Annotated Methylpentynol Not Annotated Epanolol Epanolol is an beta blocker. Meclofenoxate Not Annotated Enprostil Not Annotated Clofibride Not Annotated Gamolenic acid An ingredient found in a variety of nutritional products. Fenofibric acid A fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. Fish oil A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement. Peanut oil A compound used to lubricate ear wax, as an emollient, and used in laxatives. Isopropyl myristate A polar skin moisturizer that is used to enhance skin penetration of drugs. Pentetic acid DTPA is widely used in industry and medicine. As a medical agent, it is approved for its use in medical imaging and for the decorporation of internally deposited radionuclides. It... beta-Sitosterol Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity. Palmidrol A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food... Hopantenic acid Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal... Gondoic acid Not Annotated Magnesium stearate Not Annotated Morrhuic acid Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil. 1,2-Distearoyllecithin Not Annotated Linoleic acid Not Annotated Ceramide NP Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3... Sacubitrilat A metabolite of LCZ696 with neprilysin inhibitory activity. Octyldodecanol Not Annotated Threonic acid Not Annotated Royal jelly Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug. Jojoba oil Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Wormwood Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Meadowfoam seed oil Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Argan oil Argan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Coconut oil Coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Sunflower oil Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Bergamot oil Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Palm oil Palm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Zinc acetate A medication used to treat zinc deficiency. Potassium acetate A medication used to treat hypokalemia. Aluminum acetate A medication used for temporary relief of skin irritation. Peracetic acid A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant. Lavender oil Not Annotated Caprylyl glycol Not Annotated Acetyl chloride Not Annotated Rosemary oil Not Annotated Ceramide AP Not Annotated Ceramide NG Not Annotated cis-Vaccenic acid Not Available Cholesterol sulfate Component of human seminal plasma & spermatozoa. Prostaglandin D2 The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important... Isoamyl alcohol Not Available gamma-Aminobutyric acid The most common inhibitory neurotransmitter in the central nervous system. Oseltamivir acid Not Available Doconexent An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. Propanoic acid An antimicrobial food additive. Rivipansel Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others. LY-518674 LY518674 has been used in trials studying the treatment of Metabolic Syndrome X. Soybean oil An oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency. Olive oil For use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products. Soy sterol Not Annotated Juniperus virginiana An extract from Juniperus virginiana used in allergy testing. Methoxy arachidonyl fluorophosphonate Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid... Flurbiprofen axetil Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients). AZD-7687 AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study). Somapacitan Somapacitan is under investigation in clinical trial NCT01706783 (A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily... Telaglenastat Telaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors). VB-201 VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis). beta-Hydroxyisovaleric acid beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.). Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). GLPG-0974 GLPG-0974 is under investigation in clinical trial NCT01721980 (Multiple Ascending Dose Study of GLPG0974 in Healthy Subjects). Thioglycolic acid Thioglycolic acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light). Norleucine Norleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women). Phosphatidyl serine A nutrient used in some supplement products. Caspofungin An echinocandin used to treat a variety of fungal infections. Remifentanil An opioid analgesic used in anesthesia. p-Coumaric acid Not Available 1alpha,24S-Dihydroxyvitamin D2 Investigated for use/treatment in parathyroid disorders. Teicoplanin For the treatment of bacterial infections caused by susceptible microorganisms. Dalbavancin An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria. Glesatinib Investigated for use/treatment in cancer/tumors (unspecified). Telavancin An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia. Eucalyptus oil An ingredient used in a variety of natural health products. Verinurad Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia. Radiprodil Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain. Ralinepag Ralinepag has been used in trials studying the treatment of Pulmonary Arterial Hypertension. Icosabutate Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study). Malacidin A Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Malacidin B Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Osbond acid Not Annotated Triethylhexanoin Not Annotated Linrodostat Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants). Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). Pemafibrate Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)). Olorofim Olorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects). Pumactant Investigated for use/treatment in asthma, lung injury, and surgical adhesions. Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. 24-Homo-1,25-dihydroxyvitamin D3 24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue. Previtamin D(3) Not Annotated KH064 Not Available 25-Hydroxycholesterol Not Available 7beta-hydroxycholesterol Not Available Lexacalcitol Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known... GW-590735 Not Available Andarine Andarine is a non-steroidal selective androgen receptor modulator. 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine Not Available 1-Dodecanol 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary... 1-Naphthoxyacetic acid Not Available Glycerol 2-phosphate Not Available R-95845 R-95845 is an inhibitor of HIV-1 reverse transcriptase. Hexadecanesulfonyl fluoride Not Available Indolepropionic acid Not Available L-Dilinoleoyllecithin Not Available 6-hydroxynorleucine Not Available N-hexadecanoylglycine Not Available sn-glycero-3-phosphoethanolamine Not Available Cadaverine Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine. tert-butanol Not Available Isocaproic acid Not Available Amphomycin Not Annotated Islatravir Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)). Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria.
- Drugs & Drug Targets