Plasmodium Infections

Also known as: Malaria / Plasmodia infections / Malaria NOS / Plasmodium infection / Malaria, unspecified / Paludism / Unspecified malaria

DrugDrug NameDrug Description
DB14033Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...
DB00608ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
DB01190ClindamycinAn antibiotic used to treat serious infections caused by susceptible anaerobic bacteria, such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, and dental infections.
DB00254DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
DB01611HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
DB00358MefloquineAn antimalarial agent used as a schizonticidal agent.
DB01087PrimaquineAn antimalarial indicated to prevent relapse of vivax malaria.
DB00205PyrimethamineAn antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
DB00359SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
DrugDrug NameTargetType
DB14033Acetyl sulfisoxazoleDihydropteroate synthasetarget
DB14033Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
DB00608ChloroquineTumor necrosis factortarget
DB00608ChloroquineToll-like receptor 9target
DB00608ChloroquineGlutathione S-transferase A2target
DB00608ChloroquineCytochrome P450 2D6enzyme
DB00608ChloroquineCytochrome P450 3A4enzyme
DB00608ChloroquineCytochrome P450 1A1enzyme
DB00608ChloroquineCytochrome P450 2C8enzyme
DB00608ChloroquineCytochrome P450 3A5enzyme
DB00608ChloroquineFe(II)-protoporphyrin IXtarget
DB00608ChloroquineGlutathione S-transferasetarget
DB00608ChloroquineP-glycoprotein 1transporter
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S ribosomal RNAtarget
DB00254Doxycycline16S ribosomal RNAtarget
DB00254DoxycyclineSolute carrier family 22 member 6transporter
DB00254DoxycyclineCytochrome P450 3A4enzyme
DB00254DoxycyclineATP-binding cassette sub-family B member 5transporter
DB01611HydroxychloroquineDNAtarget
DB01611HydroxychloroquineToll-like receptor 7target
DB01611HydroxychloroquineToll-like receptor 9target
DB01611HydroxychloroquineCytochrome P450 2D6enzyme
DB01611HydroxychloroquineP-glycoprotein 1transporter
DB01611HydroxychloroquineSerum albumincarrier
DB01611Hydroxychloroquinealpha1-acid glycoproteincarrier
DB01611HydroxychloroquineCytochrome P450 3A4enzyme
DB01611HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
DB00358MefloquineHemoglobin subunit alphatarget
DB00358MefloquineCholinesteraseenzyme
DB00358MefloquineCytochrome P450 3A4enzyme
DB00358MefloquineAdenosine receptor A2atarget
DB00358MefloquineFe(II)-protoporphyrin IXtarget
DB00358MefloquineP-glycoprotein 1transporter
DB00358MefloquineCytochrome P450 19A1enzyme
DB00358MefloquineAcetylcholinesteraseenzyme
DB01087PrimaquineCytochrome P450 1A1enzyme
DB01087PrimaquineCytochrome P450 1A2enzyme
DB01087PrimaquineCytochrome P450 3A4enzyme
DB01087PrimaquineKeratin, type II cytoskeletal 7target
DB01087PrimaquineCytochrome P450 1B1enzyme
DB01087PrimaquineCytochrome P450 2D6enzyme
DB01087PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
DB01087PrimaquineFe(II)-protoporphyrin IXtarget
DB01087PrimaquineP-glycoprotein 1transporter
DB00205PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB00205PyrimethamineDihydrofolate reductasetarget
DB00205PyrimethamineCytochrome P450 2C8enzyme
DB00205PyrimethamineBeta-hexosaminidase subunit betatarget
DB00205PyrimethamineMultidrug and toxin extrusion protein 1transporter
DB00205PyrimethamineMultidrug and toxin extrusion protein 2transporter
DB00359SulfadiazineCytochrome P450 2C9enzyme
DB00359SulfadiazineDihydropteroate synthetasetarget
DB00359SulfadiazineCytochrome P450 2C8enzyme
DB00359SulfadiazineCytochrome P450 3A4enzyme
DrugDrug NamePhaseStatusCount
DB00709Lamivudine0Completed1
DB01601Lopinavir0Completed1
DB00238Nevirapine0Completed1
DB00503Ritonavir0Completed1
DB00495Zidovudine0Completed1
DB13054ACT-4518401Completed1
DB00613Amodiaquine1Completed2
DB11809Artefenomel1Completed8
DB11809Artefenomel1Terminated1
DB06697Artemether1Active Not Recruiting2
DB06697Artemether1Completed5
DB09274Artesunate1Completed9
DB01117Atovaquone1Completed2
DB00207Azithromycin1Completed2
DB00608Chloroquine1Completed7
DB12314Chlorproguanil1Suspended1
DB09065Cobicistat1Completed1
DB09065Cobicistat1Recruiting1
DB00250Dapsone1Suspended1
DB08930Dolutegravir1Completed1
DB00625Efavirenz1Completed2
DB10989Hepatitis A Vaccine1Completed1
DB11627Hepatitis B Vaccine (Recombinant)1Active Not Recruiting1
DB11627Hepatitis B Vaccine (Recombinant)1Completed1
DB11627Hepatitis B Vaccine (Recombinant)1Unknown Status2
DB00602Ivermectin1Completed1
DB01601Lopinavir1Completed2
DB06708Lumefantrine1Active Not Recruiting2
DB06708Lumefantrine1Completed5
DB05477MUC1 Dendritic Cell Vaccine1Completed1
DB00742Mannitol1Completed1
DB00563Methotrexate1Completed1
DB00264Metoprolol1Completed1
DB15483Modified vaccinia ankara1Completed2
DB10798Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen1Active Not Recruiting1
DB10798Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen1Completed2
DB10799Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen1Active Not Recruiting1
DB10799Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen1Completed2
DB10801Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen1Active Not Recruiting1
DB10801Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen1Completed2
DB10800Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen1Active Not Recruiting1
DB10800Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen1Completed2
DB01087Primaquine1Completed5
DB01131Proguanil1Completed2
DB00205Pyrimethamine1Completed3
DB00205Pyrimethamine1Not Yet Recruiting1
DB12975Pyronaridine1Completed5
DB10283Rabies virus inactivated antigen, A1Completed3
DB10283Rabies virus inactivated antigen, A1Unknown Status1
DB13085Riamet1Completed1
DB00503Ritonavir1Completed3
DB00412Rosiglitazone1Terminated1
DB01098Rosuvastatin1Terminated1
DB12659SJ-7331Recruiting1
DB01299Sulfadoxine1Completed1
DB01299Sulfadoxine1Not Yet Recruiting1
DB06608Tafenoquine1Completed1
DB11251Tocopherol1Completed1
DB00613Amodiaquine1 / 2Completed3
DB11809Artefenomel1 / 2Completed2
DB11809Artefenomel1 / 2Terminated1
DB06697Artemether1 / 2Completed1
DB09274Artesunate1 / 2Completed1
DB01117Atovaquone1 / 2Completed1
DB00608Chloroquine1 / 2Recruiting1
DB12397DSM-2651 / 2Completed1
DB12397DSM-2651 / 2Terminated1
DB00602Ivermectin1 / 2Completed1
DB06708Lumefantrine1 / 2Completed1
DB00358Mefloquine1 / 2Completed1
DB15483Modified vaccinia ankara1 / 2Completed1
DB05144PEV3A1 / 2Completed1
DB13941Piperaquine1 / 2Completed1
DB01087Primaquine1 / 2Completed2
DB01131Proguanil1 / 2Completed2
DB00205Pyrimethamine1 / 2Completed3
DB00205Pyrimethamine1 / 2Recruiting1
DB00205Pyrimethamine1 / 2Unknown Status1
DB10283Rabies virus inactivated antigen, A1 / 2Completed1
DB01299Sulfadoxine1 / 2Completed3
DB01299Sulfadoxine1 / 2Unknown Status1
DB00316Acetaminophen2Recruiting1
DB09278Activated charcoal2Completed1
DB00855Aminolevulinic acid2Not Yet Recruiting1
DB00613Amodiaquine2Completed6
DB11809Artefenomel2Completed1
DB06697Artemether2Active Not Recruiting1
DB06697Artemether2Not Yet Recruiting1
DB06697Artemether2Recruiting2
DB13132Artemisinin2Not Yet Recruiting1
DB11638Artenimol2Completed4
DB11638Artenimol2Recruiting1
DB09274Artesunate2Completed9
DB01117Atovaquone2Completed2
DB01117Atovaquone2Recruiting1
DB00207Azithromycin2Recruiting1
DB00207Azithromycin2Unknown Status1
DB12768BCG vaccine2Completed1
DB00608Chloroquine2Not Yet Recruiting1
DB00608Chloroquine2Recruiting1
DB00608Chloroquine2Terminated1
DB12314Chlorproguanil2Completed1
DB12306Cipargamin2Completed2
DB12306Cipargamin2Recruiting1
DB01190Clindamycin2Completed2
DB01190Clindamycin2Unknown Status1
DB00250Dapsone2Completed1
DB02948Fosmidomycin2Completed2
DB02948Fosmidomycin2Unknown Status2
DB02948Fosmidomycin2Withdrawn1
DB10990Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen2Completed1
DB10989Hepatitis A Vaccine2Recruiting1
DB11627Hepatitis B Vaccine (Recombinant)2Completed3
DB01050Ibuprofen2Recruiting1
DB00602Ivermectin2Completed1
DB06708Lumefantrine2Active Not Recruiting1
DB06708Lumefantrine2Not Yet Recruiting1
DB06708Lumefantrine2Recruiting2
DB06708Lumefantrine2Terminated1
DB05477MUC1 Dendritic Cell Vaccine2Not Yet Recruiting1
DB00358Mefloquine2Completed2
DB09241Methylene blue2Completed2
DB15483Modified vaccinia ankara2Completed2
DB10798Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen2Recruiting1
DB10799Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen2Recruiting1
DB10801Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen2Recruiting1
DB10800Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen2Recruiting1
DB13941Piperaquine2Completed4
DB13941Piperaquine2Recruiting1
DB01087Primaquine2Completed2
DB01087Primaquine2Terminated1
DB01131Proguanil2Completed2
DB01131Proguanil2Recruiting1
DB00205Pyrimethamine2Completed2
DB00205Pyrimethamine2Recruiting1
DB00908Quinidine2Completed1
DB00468Quinine2Completed2
DB10283Rabies virus inactivated antigen, A2Active Not Recruiting1
DB10283Rabies virus inactivated antigen, A2Completed3
DB10289Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB10290Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB10291Streptococcus pneumoniae type 19f capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB10292Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB10286Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB10287Streptococcus pneumoniae type 6b capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB10288Streptococcus pneumoniae type 9v capsular polysaccharide diphtheria crm197 protein conjugate antigen2Completed1
DB01299Sulfadoxine2Completed2
DB01299Sulfadoxine2Recruiting1
DB06608Tafenoquine2Completed2
DB06608Tafenoquine2Terminated1
DB10803Typhoid Vi polysaccharide vaccine2Recruiting1
DB10805Yellow Fever Vaccine2Completed1
DB00518Albendazole2 / 3Completed1
DB00613Amodiaquine2 / 3Completed5
DB06697Artemether2 / 3Completed2
DB11638Artenimol2 / 3Terminated1
DB09274Artesunate2 / 3Completed2
DB09274Artesunate2 / 3Withdrawn1
DB00608Chloroquine2 / 3Completed1
DB12314Chlorproguanil2 / 3Completed1
DB00250Dapsone2 / 3Completed1
DB14618Influenza A virus A/Brisbane/59/2007 (H1N1) hemagglutinin antigen (formaldehyde inactivated)2 / 3Withdrawn1
DB14617Influenza A virus A/Uruguay/716/2007(H3N2) hemagglutinin antigen (formaldehyde inactivated)2 / 3Withdrawn1
DB14385Influenza B virus B/Brisbane/60/2008 hemagglutinin antigen (formaldehyde inactivated)2 / 3Withdrawn1
DB00602Ivermectin2 / 3Completed1
DB06708Lumefantrine2 / 3Completed2
DB00358Mefloquine2 / 3Completed1
DB00358Mefloquine2 / 3Withdrawn1
DB13941Piperaquine2 / 3Completed1
DB13941Piperaquine2 / 3Terminated1
DB01087Primaquine2 / 3Completed2
DB01087Primaquine2 / 3Terminated1
DB00205Pyrimethamine2 / 3Completed7
DB10283Rabies virus inactivated antigen, A2 / 3Active Not Recruiting1
DB01299Sulfadoxine2 / 3Completed7
DB00316Acetaminophen3Recruiting1
DB11200Aluminum zirconium octachlorohydrex gly3Completed1
DB00613Amodiaquine3Completed18
DB06697Artemether3Active Not Recruiting1
DB06697Artemether3Completed18
DB06697Artemether3Unknown Status1
DB11638Artenimol3Active Not Recruiting2
DB11638Artenimol3Completed11
DB11638Artenimol3Not Yet Recruiting2
DB11638Artenimol3Recruiting3
DB11638Artenimol3Unknown Status1
DB09274Artesunate3Active Not Recruiting1
DB09274Artesunate3Completed26
DB00207Azithromycin3Completed4
DB12768BCG vaccine3Completed1
DB12768BCG vaccine3Recruiting1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)3Completed1
DB10992Bordetella pertussis pertactin antigen (formaldehyde inactivated)3Completed1
DB10991Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)3Completed1
DB00608Chloroquine3Completed7
DB00608Chloroquine3Suspended1
DB00608Chloroquine3Withdrawn1
DB12314Chlorproguanil3Completed6
DB12314Chlorproguanil3Terminated1
DB01190Clindamycin3Completed2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)3Completed1
DB00250Dapsone3Completed6
DB00250Dapsone3Terminated1
DB11282Diethyltoluamide3Unknown Status1
DB12496Dihydroxyacetone phosphate3Completed1
DB00625Efavirenz3Completed2
DB00158Folic acid3Completed1
DB02948Fosmidomycin3Completed1
DB11627Hepatitis B Vaccine (Recombinant)3Completed1
DB01005Hydroxyurea3Completed1
DB01005Hydroxyurea3Recruiting1
DB00602Ivermectin3Enrolling by Invitation1
DB00602Ivermectin3Not Yet Recruiting1
DB00602Ivermectin3Recruiting1
DB00709Lamivudine3Completed1
DB01601Lopinavir3Completed2
DB06708Lumefantrine3Active Not Recruiting1
DB06708Lumefantrine3Completed18
DB06708Lumefantrine3Unknown Status1
DB00358Mefloquine3Active Not Recruiting1
DB00358Mefloquine3Completed5
DB00238Nevirapine3Completed1
DB13941Piperaquine3Active Not Recruiting2
DB13941Piperaquine3Completed13
DB13941Piperaquine3Not Yet Recruiting2
DB13941Piperaquine3Recruiting3
DB13941Piperaquine3Unknown Status1
DB05804Prasterone sulfate3Suspended1
DB00635Prednisone3Withdrawn1
DB01087Primaquine3Completed5
DB00205Pyrimethamine3Active Not Recruiting1
DB00205Pyrimethamine3Completed18
DB00205Pyrimethamine3Recruiting1
DB00205Pyrimethamine3Terminated1
DB12975Pyronaridine3Completed5
DB00468Quinine3Completed2
DB10283Rabies virus inactivated antigen, A3Completed3
DB13085Riamet3Completed2
DB00503Ritonavir3Completed2
DB10303Rotavirus vaccine3Completed1
DB10317Rubella virus vaccine3Active Not Recruiting1
DB01299Sulfadoxine3Active Not Recruiting1
DB01299Sulfadoxine3Completed18
DB01299Sulfadoxine3Recruiting1
DB01299Sulfadoxine3Terminated1
DB01015Sulfamethoxazole3Completed3
DB00664Sulfametopyrazine3Completed1
DB00440Trimethoprim3Completed3
DB10805Yellow Fever Vaccine3Active Not Recruiting1
DB10805Yellow Fever Vaccine3Completed1
DB00495Zidovudine3Completed1
DB00316Acetaminophen4Unknown Status1
DB00518Albendazole4Unknown Status1
DB00613Amodiaquine4Completed13
DB00613Amodiaquine4Suspended1
DB00613Amodiaquine4Unknown Status2
DB06697Artemether4Completed24
DB06697Artemether4Not Yet Recruiting1
DB06697Artemether4Terminated3
DB06697Artemether4Unknown Status4
DB11638Artenimol4Completed7
DB11638Artenimol4Recruiting1
DB11638Artenimol4Unknown Status3
DB09274Artesunate4Active Not Recruiting2
DB09274Artesunate4Completed17
DB09274Artesunate4Recruiting1
DB09274Artesunate4Suspended1
DB09274Artesunate4Terminated1
DB09274Artesunate4Unknown Status2
DB01117Atovaquone4Active Not Recruiting1
DB01117Atovaquone4Completed4
DB00207Azithromycin4Recruiting1
DB12768BCG vaccine4Terminated1
DB00608Chloroquine4Completed5
DB00608Chloroquine4Terminated1
DB00608Chloroquine4Withdrawn1
DB00158Folic acid4Completed1
DB06708Lumefantrine4Completed24
DB06708Lumefantrine4Not Yet Recruiting1
DB06708Lumefantrine4Terminated3
DB06708Lumefantrine4Unknown Status4
DB00358Mefloquine4Completed4
DB00358Mefloquine4Recruiting1
DB00358Mefloquine4Terminated1
DB04930Permethrin4Recruiting1
DB13941Piperaquine4Completed9
DB13941Piperaquine4Recruiting1
DB13941Piperaquine4Unknown Status3
DB01058Praziquantel4Unknown Status1
DB01087Primaquine4Completed5
DB01087Primaquine4Not Yet Recruiting1
DB01087Primaquine4Recruiting3
DB01087Primaquine4Withdrawn1
DB01131Proguanil4Active Not Recruiting1
DB01131Proguanil4Completed4
DB00205Pyrimethamine4Completed12
DB00205Pyrimethamine4Terminated2
DB00205Pyrimethamine4Unknown Status2
DB00468Quinine4Completed3
DB00468Quinine4Unknown Status1
DB13085Riamet4Completed4
DB01299Sulfadoxine4Completed12
DB01299Sulfadoxine4Terminated2
DB01299Sulfadoxine4Unknown Status1
DB01015Sulfamethoxazole4Completed1
DB00440Trimethoprim4Completed1
DB00316AcetaminophenNot AvailableCompleted2
DB00518AlbendazoleNot AvailableCompleted2
DB00613AmodiaquineNot AvailableCompleted5
DB01060AmoxicillinNot AvailableCompleted2
DB06697ArtemetherNot AvailableCompleted13
DB06697ArtemetherNot AvailableNot Yet Recruiting1
DB13132ArtemisininNot AvailableCompleted2
DB11638ArtenimolNot AvailableActive Not Recruiting1
DB11638ArtenimolNot AvailableCompleted3
DB09274ArtesunateNot AvailableCompleted12
DB09274ArtesunateNot AvailableTerminated1
DB09274ArtesunateNot AvailableWithdrawn1
DB01117AtovaquoneNot AvailableCompleted3
DB00207AzithromycinNot AvailableCompleted1
DB00608ChloroquineNot AvailableCompleted7
DB00608ChloroquineNot AvailableTerminated1
DB12314ChlorproguanilNot AvailableCompleted2
DB00250DapsoneNot AvailableCompleted2
DB00250DapsoneNot AvailableTerminated1
DB12496Dihydroxyacetone phosphateNot AvailableActive Not Recruiting1
DB04326Dihydroxyacetone phosphateNot AvailableCompleted1
DB00254DoxycyclineNot AvailableCompleted1
DB01592IronNot AvailableCompleted1
DB01592IronNot AvailableTerminated1
DB06708LumefantrineNot AvailableCompleted12
DB06708LumefantrineNot AvailableNot Yet Recruiting1
DB00358MefloquineNot AvailableCompleted5
DB13941PiperaquineNot AvailableActive Not Recruiting1
DB13941PiperaquineNot AvailableCompleted3
DB13941PiperaquineNot AvailableTerminated1
DB01058PraziquantelNot AvailableCompleted2
DB01087PrimaquineNot AvailableCompleted2
DB01087PrimaquineNot AvailableUnknown Status1
DB01131ProguanilNot AvailableCompleted3
DB00205PyrimethamineNot AvailableCompleted15
DB00205PyrimethamineNot AvailableTerminated3
DB00468QuinineNot AvailableCompleted1
DB00412RosiglitazoneNot AvailableRecruiting1
DB01299SulfadoxineNot AvailableCompleted15
DB01299SulfadoxineNot AvailableTerminated2