Hypotension

Also known as: 2. Hypotension / Low Blood Pressure / Drop of blood pressure / BP fell / Drop in blood pressure / Blood pressure dropped / Blood pressure decreased / Hypotension, unspecified / Low BP / Fall in blood pressure / BP lowered / Hypotension NOS / Arterial pressure NOS decreased / Arterial hypotension / Blood pressure drop arterial / Pressure arterial decreased / Lowered blood pressure / Arterial blood pressure decreased / Blood pressure low

DrugDrug NameDrug Description
DB11842Angiotensin IIA peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock.
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB00368NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
DB00388PhenylephrineAn alpha-1 adrenergic antagonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DrugDrug NameTargetType
DB11842Angiotensin IIType-1 angiotensin II receptortarget
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB00368NorepinephrinePhenylalanine-4-hydroxylasetarget
DB00368NorepinephrineAlpha-1A adrenergic receptortarget
DB00368NorepinephrineAlpha-1B adrenergic receptortarget
DB00368NorepinephrineAlpha-1D adrenergic receptortarget
DB00368NorepinephrineAlpha-2A adrenergic receptortarget
DB00368NorepinephrineAlpha-2B adrenergic receptortarget
DB00368NorepinephrineAlpha-2C adrenergic receptortarget
DB00368NorepinephrineBeta-1 adrenergic receptortarget
DB00368NorepinephrineBeta-2 adrenergic receptortarget
DB00368NorepinephrineBeta-3 adrenergic receptortarget
DB00368NorepinephrineSolute carrier family 22 member 2transporter
DB00368NorepinephrineSolute carrier family 22 member 3transporter
DB00368NorepinephrineSolute carrier family 22 member 5transporter
DB00368NorepinephrineSolute carrier family 22 member 1transporter
DB00368NorepinephrinePOU domain, class 5, transcription factor 1transporter
DB00368NorepinephrineSodium-dependent noradrenaline transportertransporter
DB00368NorepinephrineSynaptic vesicular amine transportertarget
DB00368NorepinephrineChromaffin granule amine transportertarget
DB00388PhenylephrineAlpha-1A adrenergic receptortarget
DB00388PhenylephrineAlpha-1B adrenergic receptortarget
DB00388PhenylephrineAmine oxidase [flavin-containing] Aenzyme
DB00388PhenylephrineAlpha-1D adrenergic receptortarget
DB00388PhenylephrineCytochrome P450 1A2enzyme
DB00388PhenylephrineSulfotransferase 1A3/1A4enzyme
DB00388PhenylephrineAmine oxidase [flavin-containing] Benzyme
DrugDrug NamePhaseStatusCount
DB00988Dopamine1Completed1
DB00988Dopamine1Unknown Status1
DB06262Droxidopa1Completed1
DB00741Hydrocortisone1Completed1
DB14009Medical Cannabis1Unknown Status1
DB00388Phenylephrine1Unknown Status1
DB00126Ascorbic acid1 / 2Completed1
DB05313MP41 / 2Completed1
DB06151Acetylcysteine2Completed1
DB00297Bupivacaine2Completed1
DB00297Bupivacaine2Unknown Status1
DB00746Deferoxamine2Completed1
DB01364Ephedrine2Completed1
DB00668Epinephrine2Completed1
DB00187Esmolol2Recruiting1
DB00813Fentanyl2Unknown Status1
DB00200Hydroxocobalamin2Not Yet Recruiting1
DB00454Meperidine2Completed1
DB00610Metaraminol2Completed1
DB09241Methylene blue2Not Yet Recruiting1
DB00683Midazolam2Completed1
DB05799NOX-1002Completed1
DB00325Nitroprusside2Completed1
DB00368Norepinephrine2Recruiting1
DB00043Omalizumab2Completed1
DB00388Phenylephrine2Completed1
DB00388Phenylephrine2Recruiting1
DB00818Propofol2Completed1
DB00302Tranexamic acid2Terminated1
DB01364Ephedrine2 / 3Completed2
DB00813Fentanyl2 / 3Recruiting1
DB00211Midodrine2 / 3Recruiting1
DB00904Ondansetron2 / 3Unknown Status1
DB00388Phenylephrine2 / 3Completed2
DB09153Sodium chloride2 / 3Recruiting1
DB00297Bupivacaine3Completed1
DB00390Digoxin3Unknown Status1
DB00988Dopamine3Terminated1
DB00055Drotrecogin alfa3Completed1
DB09106Hydroxyethyl Starch3Completed2
DB05313MP43Completed2
DB00211Midodrine3Completed1
DB00368Norepinephrine3Completed1
DB00368Norepinephrine3Recruiting1
DB00904Ondansetron3Completed1
DB00904Ondansetron3Recruiting1
DB00388Phenylephrine3Completed1
DB00388Phenylephrine3Recruiting1
DB00750Prilocaine3Completed1
DB00899Remifentanil3Completed1
DB00296Ropivacaine3Terminated1
DB00572Atropine4Completed1
DB00297Bupivacaine4Completed3
DB00429Carboprost tromethamine4Completed1
DB01234Dexamethasone4Completed1
DB00841Dobutamine4Completed1
DB12313Dopexamine4Completed1
DB06262Droxidopa4Recruiting1
DB01364Ephedrine4Completed3
DB00668Epinephrine4Completed2
DB00695Furosemide4Completed1
DB09106Hydroxyethyl Starch4Completed1
DB09106Hydroxyethyl Starch4Recruiting1
DB09106Hydroxyethyl Starch4Unknown Status1
DB00753Isoflurane4Terminated1
DB01002Levobupivacaine4Active Not Recruiting1
DB01002Levobupivacaine4Completed1
DB00583Levocarnitine4Unknown Status1
DB00353Methylergometrine4Completed1
DB00211Midodrine4Withdrawn1
DB00929Misoprostol4Completed1
DB00295Morphine4Completed1
DB00368Norepinephrine4Completed4
DB00368Norepinephrine4Recruiting1
DB00904Ondansetron4Completed1
DB00904Ondansetron4Recruiting1
DB00107Oxytocin4Completed2
DB00388Phenylephrine4Completed6
DB00388Phenylephrine4Recruiting2
DB01236Sevoflurane4Recruiting1
DB01236Sevoflurane4Terminated1
DB09153Sodium chloride4Completed1
DB00820Tadalafil4Completed1
DB00802AlfentanilNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic acidNot AvailableRecruiting1
DB09009ArticaineNot AvailableCompleted1
DB00572AtropineNot AvailableCompleted1
DB01086BenzocaineNot AvailableCompleted1
DB00559BosentanNot AvailableRecruiting1
DB00297BupivacaineNot AvailableCompleted1
DB00297BupivacaineNot AvailableNot Yet Recruiting1
DB12926CafedrineNot AvailableCompleted1
DB01413CefepimeNot AvailableRecruiting1
DB01161ChloroprocaineNot AvailableCompleted1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00363ClozapineNot AvailableRecruiting1
DB01189DesfluraneNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableCompleted1
DB00841DobutamineNot AvailableCompleted1
DB00988DopamineNot AvailableCompleted3
DB01364EphedrineNot AvailableCompleted4
DB01364EphedrineNot AvailableNot Yet Recruiting1
DB01364EphedrineNot AvailableRecruiting3
DB00668EpinephrineNot AvailableCompleted3
DB00668EpinephrineNot AvailableUnknown Status1
DB00828FosfomycinNot AvailableRecruiting1
DB00986GlycopyrroniumNot AvailableCompleted1
DB00889GranisetronNot AvailableCompleted1
DB00502HaloperidolNot AvailableRecruiting1
DB09106Hydroxyethyl StarchNot AvailableCompleted2
DB00753IsofluraneNot AvailableCompleted1
DB01064IsoprenalineNot AvailableCompleted1
DB00598LabetalolNot AvailableRecruiting1
DB01002LevobupivacaineNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB08815LurasidoneNot AvailableRecruiting1
DB00961MepivacaineNot AvailableCompleted1
DB00474MethohexitalNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB00211MidodrineNot AvailableWithdrawn1
DB00235MilrinoneNot AvailableCompleted1
DB01618MolindoneNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB00727NitroglycerinNot AvailableCompleted1
DB00368NorepinephrineNot AvailableCompleted5
DB00368NorepinephrineNot AvailableRecruiting2
DB00904OndansetronNot AvailableTerminated1
DB00904OndansetronNot AvailableUnknown Status1
DB00497OxycodoneNot AvailableRecruiting1
DB00312PentobarbitalNot AvailableRecruiting1
DB00388PhenylephrineNot AvailableCompleted5
DB00388PhenylephrineNot AvailableRecruiting4
DB00319PiperacillinNot AvailableRecruiting1
DB00750PrilocaineNot AvailableCompleted1
DB00721ProcaineNot AvailableCompleted1
DB00818PropofolNot AvailableCompleted3
DB09290RamosetronNot AvailableCompleted1
DB09290RamosetronNot AvailableUnknown Status1
DB00728RocuroniumNot AvailableRecruiting1
DB00296RopivacaineNot AvailableCompleted2
DB08839SerotoninNot AvailableCompleted1
DB00658SevelamerNot AvailableRecruiting1
DB01236SevofluraneNot AvailableCompleted1
DB09153Sodium chlorideNot AvailableCompleted2
DB00421SpironolactoneNot AvailableRecruiting1
DB01606TazobactamNot AvailableRecruiting1
DB02638TerlipressinNot AvailableCompleted1
DB09085TetracaineNot AvailableCompleted1
DB12927TheodrenalineNot AvailableCompleted1
DB00684TobramycinNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB00067VasopressinNot AvailableCompleted3
DB01339VecuroniumNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1