Bacterial Infections

Also known as: Bacterial infections NEC / Infections, Bacterial / Infections - Bacterial / Bacterial Infection / Infection, Bacterial / Bacterial disease / Bacterial infection of unspecified site / Bacterial infectious disorders / Bacterial infection NOS / Infection bacterial

DrugDrug NameDrug Description
DB00415AmpicillinAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
DB09060AvibactamAvibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract infections, including pyelonephritis caused by antibiotic resistant-pathogens, including those caused by multi-drug resistant gram-negative bacterial pathogens. As there is limited clinical safety and efficacy data, Avycaz should be reserved for patients over 18 years old who have limited or not alternative treatment options.
DB00626BacitracinBacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically. Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis.
DB01053BenzylpenicillinBenzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans*, and *Enterococcus faecalis*. The natural penicillins may also be used as first or second line agents against susceptible gram positive aerobic bacilli such as *Bacillus anthracis*, *Corynebacterium diphtheriae*, and *Erysipelothrix rhusiopathiae*. Natural penicillins have limited activity against gram negative organisms; however, they may be used in some cases to treat infections caused by *Neisseria meningitidis* and *Pasteurella*. They are not generally used to treat anaerobic infections. Resistance patterns, susceptibility and treatment guidelines vary across regions.
DB13960BronopolBronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an inorganic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives [F13]. Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, including oil field systems, air washer systems, air conditioning or humidifying systems, cooling water systems, papermills, absorbent clays, metal working fluids, printing inks, paints, adhesives and consumer products [F13]. Compared to other aliphatic halogen-nitro compounds, bronopol is more stable to hydrolysis in aqueous media under normal conditions [A32792]. The inhibitory activity against various bacteria, including _Pseudomonas aeruginosa_, was demonstrated _in vitro_ [A32792]. Bronopol is approved for use in antibacterial OTC products in Canada.
DB00833CefaclorSemisynthetic, broad-spectrum antibiotic derivative of cephalexin.
DB01140CefadroxilLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
DB01327CefazolinA semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
DB01066CefditorenCefditoren is a third-generation cephalosporin antibiotic for oral use. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
DB01413CefepimeCefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents. Cefepime is usually reserved to treat severe nosocomial pneumonia, infections caused by multi-resistant microorganisms (e.g. Pseudomonas aeruginosa) and empirical treatment of febrile neutropenia.
DB00493CefotaximeCefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
DB01330CefotetanA semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms. [PubChem]
DB01331CefoxitinCefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
DB01416CefpodoximeCefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
DB01150CefprozilCefprozil is a cephalosporin antibiotic. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections.
DB06590Ceftaroline fosamilCeftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
DB00438CeftazidimeSemisynthetic, broad-spectrum antibacterial derived from cephaloridine and used especially for Pseudomonas and other gram-negative infections in debilitated patients.
DB01415CeftibutenCeftibuten is a third-generation cephalosporin antibiotic. It is an orally-administered agent. Cefalexin is used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
DB01212CeftriaxoneA broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears. [PubChem]
DB01112CefuroximeBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus. [PubChem]
DB00446ChloramphenicolAn antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
DB01597CilastatinA renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. [PubChem]
DB01211ClarithromycinClarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
DB01190ClindamycinClindamycin is a semisynthetic lincosamide antibiotic that has largely replaced lincomycin due to an improved side effect profile. Clindamycin inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. It may be bacteriostatic or bactericidal depending on the organism and drug concentration.
DB01147CloxacillinA semi-synthetic antibiotic that is a chlorinated derivative of oxacillin.
DB01111ColistimethateColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
DB06219DalbavancinDalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin. Modifications from these older glycoprotein classes allowed a similar mechanism of action with increased activity and once weekly dosing. Its use is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by the following gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), S. pyogenes, S. agalactiae, and S. anginosus group (including S. anginosus, S. intermedius, and S. constellatus). Dalbavancin acts by interfering with cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking.
DB01764DalfopristinDalfopristin is a combination of two antibiotics (Dalfopristin and quinupristin) used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. It is not effective against Enterococcus faecalis infections. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis.
DB06211DoripenemDoripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates, resulting in a premature termination of the trial. The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated pneumonia and to reiterate its safety and efficacy for its approved indications.
DB00199ErythromycinErythromycin is a macrolide antibiotic produced by Saccharopolyspora erythraea (formerly Streptomyces erythraeus). It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits; binding inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. Erythromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
DB00898EthanolA clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
DB01155GemifloxacinGemifloxacin is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.
DB00798GentamicinA complex of three different closely related aminoglycoside sulfates, Gentamicins C1, C2, and C1a, obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (genetic translation).
DB00406Gentian VioletA dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
DB00756HexachloropheneA chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
DB01598ImipenemSemisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilastatin, a renal dipeptidase inhibitor. [PubChem]
DB01137LevofloxacinA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
DB00601LinezolidLinezolid is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). The drug works by inhibiting the initiation of bacterial protein synthesis.
DB00760MeropenemMeropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI). Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. The treatment aims to resolve infection-related symptoms and achieve negative urine culture, where the infections are proven or strongly suspected to be caused by susceptible bacteria.
DB00916MetronidazoleA nitroimidazole used to treat amebiasis; vaginitis; trichomonas infections; giardiasis; anaerobic bacteria; and treponemal infections. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
DB01017MinocyclineA tetracycline analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant staphylococcus infections. [PubChem]
DB00607NafcillinA semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360].
DB00994NeomycinA component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed). Neomycin is a bactericidal aminoglycoside antibiotic that binds to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and acceptor tRNA sites and results in the production of non-functional or toxic peptides.
DB01165OfloxacinA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
DB00417PhenoxymethylpenicillinPhenoxymethylpenicillin (Penicillin V) is narrow spectrum antibiotic used to treat mild to moderate infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered orally. Penicillin V may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Aminoglycosides may be added for synergy against group B streptococcus (S. agalactiae), S. viridans, and Enterococcus faecalis. The natural penicillins may also be used as first or second line agents against susceptible gram positive aerobic bacilli such as Bacillus anthracis, Corynebacterium diphtheriae, and Erysipelothrix rhusiopathiae. Natural penicillins have limited activity against gram negative organisms; however, they may be used in some cases to treat infections caused by Neisseria meningitidis and Pasteurella. They are not generally used to treat anaerobic infections. Resistance patterns, susceptibility and treatment guidelines vary across regions.
DB00781Polymyxin B SulfatePolymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. All gram-positive bacteria, fungi, and the gram-negative cocci, N. gonorrhea and N. menigitidis, are resistant. It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa.
DB01032ProbenecidThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. [PubChem]
DB09320Procaine benzylpenicillinProcaine benzylpenicillin (INN), also known as procaine G penicillin, is an antibiotic useful for the treatment of a number of bacterial infections. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Following deep intramuscular injection, it is slowly absorbed into the circulation and hydrolysed to benzylpenicillin — thus it is used where prolonged low concentrations of benzylpenicillin are required. This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection of penicillin. It is widely used in veterinary settings. Benzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections.
DB01369QuinupristinQuinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis. The combination of the two components acts synergistically and is more effective in vitro than each component alone.
DB01220RifaximinRifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel syndrome (IBS-D) in adult women and men. It is marketed under the brand name Xifaxan by Salix Pharmaceuticals.
DB06145SpiramycinSpiramycin is a macrolide antimicrobial agent with activity against gram-positive organisms, including Streptococcus pyogenes (group A beta-hemolytic streptococci), S. viridans, Corynebacterium diphtheriae, and methicillin-sensitive Staphylococcus aureus. Spiramycin is a 16-membered ring macrolide. It was discovered in 1952 as a product of Streptomyces ambofaciens. As a preparation for oral administration it has been used since 1955, in 1987 also the parenteral form was introduced into practice. The antibacterial spectrum comprises Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of spirochetes, Toxoplasma gondii and Cryptosporidium species. Enterobacteria, pseudomonads and pathogenic moulds are resistant. Its action is mainly bacteriostatic, on highly sensitive strains it exerts a bactericide action.
DB01082StreptomycinStreptomycin is an aminoglycoside antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by binding to the 30S ribosomal subunit of susceptible organisms and disrupting the initiation and elongation steps in protein synthesis. It is bactericidal due to effects that are not fully understood.
DB09324SulbactamSulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys antibiotic activity.
DB01015SulfamethoxazoleA bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
DB09042Tedizolid PhosphateTedizolid Phosphate is an oxazolidinone-class antibiotic prodrug indicated in adults for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of several Gram-positive bacteria. Following administration via oral or intravenous route, tedizolid phosphate prodrug is converted by plasma phosphatases to its active moiety, tedizolid. Once activated, tedizolid exerts its bacteriostatic microbial activity through inhibition of protein synthesis by binding to the 50S ribosomal subunit of susceptible bacteria. Tedizolid is an effective and potent alternative to linezolid for the treatment of patients with Gram-positive ABSSSI due to MRSA or MSSA. Increased potency allows for once daily dosing with reduced total dosages, improving the side effect profile of this drug. Of note, the minimum inhibitory concentrations of tedizolid appear to be largely unaffected by the chloramphenicol-florfenicol resistance (cfr) gene, which has been implicated in a number of published linezolid-resistant organism outbreaks.
DB06402TelavancinTelavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
DB00759TetracyclineTetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells.
DB00560TigecyclineTigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was given a U.S. Food and Drug Administration (FDA) fast-track approval and was approved on June 17, 2005. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus.
DrugDrug NameTargetType
DB00415AmpicillinSerum albumincarrier
DB00415AmpicillinSolute carrier family 22 member 5transporter
DB00415AmpicillinSolute carrier family 15 member 1transporter
DB00415AmpicillinSolute carrier family 15 member 2transporter
DB00415AmpicillinPenicillin-binding protein 2atarget
DB00415AmpicillinPenicillin-binding protein 1btarget
DB00415AmpicillinPenicillin-binding protein 3target
DB00415AmpicillinPenicillin-binding protein 1Atarget
DB00415AmpicillinPenicillin-binding protein 2Btarget
DB00415AmpicillinMonocarboxylate transporter 1transporter
DB00415AmpicillinSolute carrier family 15 member 1target
DB00415AmpicillinSolute carrier family 15 member 2target
DB00415AmpicillinAngiopoietin-1 receptortarget
DB09060AvibactamBeta-lactamase TEMtarget
DB09060AvibactamBeta-lactamase CTX-Mtarget
DB09060AvibactamBeta-lactamase AmpCtarget
DB09060AvibactamBeta-lactamase SHV-1target
DB09060AvibactamBeta-lactamase SHV-2target
DB09060AvibactamBeta-lactamase SHV-1target
DB09060AvibactamClass D OXA-48 carbapenemasetarget
DB09060AvibactamCarbapenem-hydrolyzing beta-lactamase KPCtarget
DB09060AvibactamBeta-lactamase CTX-M-15target
DB09060AvibactamExtended-spectrum beta-lactamase PER-1target
DB09060AvibactamCanalicular multispecific organic anion transporter 1transporter
DB09060AvibactamSolute carrier family 22 member 8transporter
DB00626BacitracinAlpha-2-macroglobulintarget
DB00626BacitracinInsulin-degrading enzymetarget
DB00626BacitracinC55-isoprenyl pyrophosphatetarget
DB01053BenzylpenicillinSolute carrier family 22 member 5transporter
DB01053BenzylpenicillinSolute carrier family 15 member 1transporter
DB01053BenzylpenicillinSolute carrier family 15 member 2transporter
DB01053BenzylpenicillinSolute carrier family 22 member 6transporter
DB01053BenzylpenicillinSolute carrier family 22 member 8transporter
DB01053BenzylpenicillinSolute carrier family 22 member 4transporter
DB01053BenzylpenicillinSolute carrier family 22 member 11transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 2B1transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 4A1transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 3A1transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 1B1transporter
DB01053BenzylpenicillinPenicillin-binding protein 3target
DB01053BenzylpenicillinBeta-lactamase TEMtarget
DB01053BenzylpenicillinSolute carrier family 22 member 8target
DB01053BenzylpenicillinSolute carrier family 15 member 1target
DB01053BenzylpenicillinSolute carrier family 15 member 2target
DB13960BronopolThiol groupstarget
DB00833CefaclorPenicillin-binding protein 1Atarget
DB00833CefaclorSolute carrier family 15 member 1transporter
DB00833CefaclorSolute carrier family 15 member 2transporter
DB00833CefaclorPenicillin-binding protein 3target
DB00833CefaclorMyeloperoxidaseenzyme
DB00833CefaclorSolute carrier family 22 member 8transporter
DB01140CefadroxilSolute carrier family 22 member 5transporter
DB01140CefadroxilSolute carrier family 15 member 1transporter
DB01140CefadroxilSolute carrier family 15 member 2transporter
DB01140CefadroxilSolute carrier family 22 member 6transporter
DB01140CefadroxilSolute carrier family 22 member 8transporter
DB01140CefadroxilPenicillin-binding protein 3target
DB01140CefadroxilPenicillin-binding protein 1Atarget
DB01140CefadroxilPenicillin-binding protein 1btarget
DB01140CefadroxilPenicillin-binding protein 2Btarget
DB01327CefazolinSerum paraoxonase/arylesterase 1target
DB01327CefazolinSerum albumincarrier
DB01327CefazolinSolute carrier family 22 member 6transporter
DB01327CefazolinSolute carrier family 22 member 8transporter
DB01327CefazolinSolute carrier family 22 member 11transporter
DB01327CefazolinPenicillin-binding protein 1Atarget
DB01327CefazolinPenicillin-binding protein 1Btarget
DB01327CefazolinPenicillin-binding protein 2target
DB01327CefazolinPenicillin-binding protein 1Ctarget
DB01327CefazolinPeptidoglycan synthase FtsItarget
DB01327CefazolinMultidrug resistance-associated protein 4transporter
DB01327CefazolinThiopurine S-methyltransferaseenzyme
DB01327CefazolinInterleukin-15target
DB01327CefazolinInterleukin-2target
DB01066CefditorenPenicillin-binding protein 1Atarget
DB01066CefditorenPenicillin-binding protein 2Btarget
DB01413CefepimeSolute carrier family 22 member 5transporter
DB01413CefepimeSolute carrier family 15 member 1transporter
DB01413CefepimeSolute carrier family 15 member 2transporter
DB01413CefepimePenicillin-binding protein 2target
DB01413CefepimePeptidoglycan synthase FtsItarget
DB01413CefepimePenicillin-binding protein 3target
DB01413CefepimePenicillin-binding protein 2target
DB00493CefotaximePenicillin-binding protein 3target
DB00493CefotaximeSolute carrier family 15 member 1transporter
DB00493CefotaximeSolute carrier family 15 member 2transporter
DB00493CefotaximeSolute carrier family 22 member 6transporter
DB00493CefotaximeSolute carrier family 22 member 8transporter
DB00493CefotaximeSolute carrier family 22 member 11transporter
DB00493CefotaximeSolute carrier family 22 member 7transporter
DB00493CefotaximePenicillin-binding protein 1btarget
DB00493CefotaximePenicillin-binding protein 2atarget
DB00493CefotaximePenicillin-binding protein 1Atarget
DB00493CefotaximePenicillin-binding protein 2Btarget
DB00493CefotaximeSolute carrier family 22 member 6target
DB00493CefotaximeSolute carrier family 22 member 8target
DB00493CefotaximeSolute carrier family 22 member 11target
DB00493CefotaximeSolute carrier family 22 member 7target
DB00493CefotaximeSolute carrier family 15 member 1target
DB00493CefotaximeSerum albumintarget
DB00493CefotaximeBeta-lactamasetarget
DB00493CefotaximeSolute carrier family 15 member 2target
DB01330CefotetanSerum albumincarrier
DB01330CefotetanPenicillin-binding protein 3target
DB01331CefoxitinBeta-lactamaseenzyme
DB01331CefoxitinPenicillin-binding protein 1Atarget
DB01331CefoxitinPenicillin-binding protein 1Btarget
DB01331CefoxitinPeptidoglycan synthase FtsItarget
DB01331CefoxitinD-alanyl-D-alanine carboxypeptidase DacAtarget
DB01331CefoxitinD-alanyl-D-alanine carboxypeptidase DacBtarget
DB01331CefoxitinD-alanyl-D-alanine carboxypeptidase DacCtarget
DB01331CefoxitinD-alanyl-D-alanine endopeptidasetarget
DB01331CefoxitinPenicillin-binding protein 3target
DB01331CefoxitinPenicillin-binding protein 1btarget
DB01331CefoxitinPenicillin-binding protein 2atarget
DB01331CefoxitinPenicillin-binding protein 1Atarget
DB01331CefoxitinPenicillin-binding protein 2Btarget
DB01416CefpodoximePeptidoglycan synthase FtsItarget
DB01150CefprozilPenicillin-binding protein 1Atarget
DB01150CefprozilPenicillin-binding protein 2xtarget
DB01150CefprozilPenicillin-binding protein 2Btarget
DB00438CeftazidimeSolute carrier family 22 member 5transporter
DB00438CeftazidimeSolute carrier family 15 member 1transporter
DB00438CeftazidimeSolute carrier family 15 member 2transporter
DB00438CeftazidimeSolute carrier family 22 member 6transporter
DB00438CeftazidimePeptidoglycan synthase FtsItarget
DB00438CeftazidimePenicillin-binding protein 3target
DB00438CeftazidimePenicillin-binding protein 1Atarget
DB00438CeftazidimePenicillin-binding protein 1Atarget
DB00438CeftazidimePenicillin-binding protein 1Btarget
DB00438CeftazidimePenicillin-binding protein 1Btarget
DB00438CeftazidimePenicillin-binding protein 2target
DB00438CeftazidimePenicillin-binding protein 2target
DB00438CeftazidimeD-alanyl-D-alanine endopeptidasetarget
DB01415CeftibutenSolute carrier family 15 member 1transporter
DB01415CeftibutenSolute carrier family 15 member 2transporter
DB01415CeftibutenPeptidoglycan synthase FtsItarget
DB01415CeftibutenPenicillin-binding protein 1Atarget
DB01415CeftibutenPenicillin-binding protein 1Btarget
DB01415CeftibutenPenicillin-binding protein 2target
DB01415CeftibutenSolute carrier family 22 member 6transporter
DB01415CeftibutenSolute carrier family 22 member 8transporter
DB01212CeftriaxoneSerum albumincarrier
DB01212CeftriaxoneSolute carrier family 15 member 1transporter
DB01212CeftriaxoneSolute carrier family 15 member 2transporter
DB01212CeftriaxoneSolute carrier family 22 member 6transporter
DB01212CeftriaxoneSolute carrier family 22 member 8transporter
DB01212CeftriaxoneSolute carrier family 22 member 11transporter
DB01212CeftriaxonePenicillin-binding protein 2Btarget
DB01212CeftriaxoneGlutamine synthetaseenzyme
DB01212CeftriaxoneSolute carrier family 22 member 11target
DB01212CeftriaxoneSolute carrier family 22 member 6target
DB01212CeftriaxoneSolute carrier family 22 member 8target
DB01212CeftriaxoneSolute carrier family 15 member 1target
DB01112CefuroximePenicillin-binding protein 1Atarget
DB01112CefuroximeSolute carrier family 15 member 1transporter
DB01112CefuroximeSolute carrier family 15 member 2transporter
DB00446ChloramphenicolCytochrome P450 2C19enzyme
DB00446ChloramphenicolCytochrome P450 3A4enzyme
DB00446ChloramphenicolCytochrome P450 3A5enzyme
DB00446ChloramphenicolCytochrome P450 3A7enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferase 3enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferaseenzyme
DB00446ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DB00446ChloramphenicolCytochrome P450 2C8enzyme
DB00446ChloramphenicolCytochrome P450 2C9enzyme
DB00446Chloramphenicol50S ribosomal protein L16target
DB00446ChloramphenicolDr hemagglutinin structural subunittarget
DB00446ChloramphenicolComplement decay-accelerating factortarget
DB00446ChloramphenicolSolute carrier family 22 member 6transporter
DB01597CilastatinDipeptidase 1target
DB01597CilastatinSolute carrier family 22 member 6transporter
DB01597CilastatinSolute carrier family 22 member 8transporter
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 2C19enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinCytochrome P450 3A7enzyme
DB01211ClarithromycinMultidrug resistance protein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinCytochrome P450 1A2enzyme
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S rRNAtarget
DB01147CloxacillinPenicillin-binding protein 1Atarget
DB01147CloxacillinBeta-lactamasetarget
DB01147CloxacillinSerum albumincarrier
DB01147CloxacillinSolute carrier family 15 member 1transporter
DB01147CloxacillinSolute carrier family 15 member 2transporter
DB01147CloxacillinSolute carrier family 22 member 6transporter
DB01147CloxacillinPenicillin-binding protein 2atarget
DB01147CloxacillinPenicillin-binding protein 2Btarget
DB01147CloxacillinPenicillin-binding protein 3target
DB01147CloxacillinD-alanyl-D-alanine carboxypeptidase DacAtarget
DB01111ColistimethateBacterial outer membranetarget
DB01764DalfopristinStreptogramin A acetyltransferasetarget
DB01764DalfopristinCytochrome P450 3A4enzyme
DB06211DoripenemDipeptidase 1enzyme
DB06211DoripenemPenicillin-binding protein 1Atarget
DB06211DoripenemPenicillin-binding protein 1Btarget
DB06211DoripenemPenicillin-binding protein 2target
DB06211DoripenemPenicillin-binding protein 3target
DB06211DoripenemPenicillin-binding protein 4target
DB00199Erythromycin23S rRNAtarget
DB00199ErythromycinCytochrome P450 3A4enzyme
DB00199ErythromycinCytochrome P450 3A7enzyme
DB00199ErythromycinMultidrug resistance protein 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1B1transporter
DB00199ErythromycinCytochrome P450 1A2enzyme
DB00199ErythromycinCytochrome P450 2B6enzyme
DB00199ErythromycinMotilin receptortarget
DB00199ErythromycinPotassium voltage-gated channel subfamily H member 2target
DB00199ErythromycinSerum albumintarget
DB00199ErythromycinCytochrome P450 3A5enzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-1target
DB00898EthanolGlutamate receptor ionotropic, NMDA 3Atarget
DB00898EthanolGlycine receptor subunit alpha-1target
DB00898EthanolGlycine receptor subunit alpha-2target
DB00898EthanolCytochrome P450 2E1enzyme
DB00898EthanolCytochrome P450 1A1enzyme
DB00898EthanolCytochrome P450 1A2enzyme
DB00898EthanolCytochrome P450 2B6enzyme
DB00898EthanolCytochrome P450 2C19enzyme
DB00898EthanolCytochrome P450 2C9enzyme
DB00898EthanolCytochrome P450 3A4enzyme
DB00898EthanolCytochrome P450 4A11enzyme
DB00898EthanolAlcohol dehydrogenase 1Aenzyme
DB00898EthanolAlcohol dehydrogenase 1Benzyme
DB00898EthanolAlcohol dehydrogenase 1Cenzyme
DB00898EthanolAlcohol dehydrogenase class-3enzyme
DB00898EthanolVoltage-dependent L-type calcium channel subunit beta-1target
DB00898Ethanol5-hydroxytryptamine receptor 3Atarget
DB00898EthanolAlcohol dehydrogenase 4enzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-2target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-10target
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-5target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-4target
DB00898EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-3target
DB00898EthanolGlutamate receptor 1target
DB00898EthanolVoltage-dependent calcium channel gamma-1 subunittarget
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-2target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-6target
DB00898EthanolGlutamate receptor 2target
DB00898EthanolGlutamate receptor 4target
DB00898EthanolGlutamate receptor 3target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-4target
DB00898EthanolNeuronal acetylcholine receptor subunit beta-2target
DB00898EthanolG protein-activated inward rectifier potassium channel 1target
DB00898EthanolG protein-activated inward rectifier potassium channel 2target
DB00898EthanolVascular cell adhesion protein 1target
DB00898EthanolEquilibrative nucleoside transporter 1target
DB00898EthanolG protein-activated inward rectifier potassium channel 4target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-7target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-9target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-1target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-2target
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00898EthanolAlcohol dehydrogenase 6enzyme
DB00898EthanolNeuronal acetylcholine receptor subunit beta-4target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-3target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-5target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-6target
DB00898EthanolNeuronal acetylcholine receptor subunit beta-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit gamma-1target
DB00898EthanolGamma-aminobutyric acid receptor subunit gamma-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit epsilontarget
DB00898EthanolGamma-aminobutyric acid receptor subunit pitarget
DB00898EthanolGamma-aminobutyric acid receptor subunit thetatarget
DB00898EthanolGamma-aminobutyric acid receptor subunit deltatarget
DB00898EthanolAlcohol dehydrogenase [NADP(+)]enzyme
DB00898EthanolEquilibrative nucleoside transporter 2target
DB00898Ethanol5-hydroxytryptamine receptor 3Etarget
DB00898Ethanol5-hydroxytryptamine receptor 3Btarget
DB00898Ethanol5-hydroxytryptamine receptor 3Dtarget
DB00898Ethanol5-hydroxytryptamine receptor 3Ctarget
DB00898EthanolVoltage-dependent calcium channel gamma-2 subunittarget
DB00898EthanolG protein-activated inward rectifier potassium channel 3target
DB00898EthanolNeural cell adhesion molecule L1target
DB01155GemifloxacinDNA gyrase subunit Atarget
DB01155GemifloxacinDNA topoisomerase 4 subunit Atarget
DB00798Gentamicin30S ribosomal protein S12target
DB00798Gentamicin16S rRNAtarget
DB00798GentamicinLow-density lipoprotein receptor-related protein 2target
DB00798GentamicinSolute carrier family 22 member 6transporter
DB00798GentamicinNH(3)-dependent NAD(+) synthetasetarget
DB00798GentamicinDihydrofolate reductasetarget
DB00406Gentian VioletDNAtarget
DB00406Gentian VioletSolute carrier family 22 member 1transporter
DB00756HexachloropheneD-lactate dehydrogenasetarget
DB00756HexachloropheneGlutamate dehydrogenase 1, mitochondrialtarget
DB00756HexachloropheneSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialtarget
DB00756HexachloropheneEstrogen receptor alphatarget
DB01598ImipenemBeta-lactamasetarget
DB01598ImipenemPenicillin-binding protein 1Atarget
DB01598ImipenemPenicillin-binding protein 1Btarget
DB01598ImipenemPenicillin-binding protein 2target
DB01598ImipenemPenicillin-binding protein 3target
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinMultidrug resistance protein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB00601Linezolid23S rRNAtarget
DB00601LinezolidAmine oxidase [flavin-containing] Aenzyme
DB00601LinezolidAmine oxidase [flavin-containing] Benzyme
DB00760MeropenemD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00760MeropenemBeta-lactamase OXA-10enzyme
DB00916MetronidazoleIron hydrogenase 1target
DB00916MetronidazoleDNAtarget
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleLanosterol 14-alpha demethylasetarget
DB01017Minocycline30S ribosomal protein S4target
DB01017Minocycline30S ribosomal protein S9target
DB01017Minocycline16S rRNAtarget
DB01017MinocyclineInterleukin-1 betatarget
DB01017MinocyclineArachidonate 5-lipoxygenasetarget
DB01017MinocyclineMatrix metalloproteinase-9target
DB01017MinocyclineVascular endothelial growth factor Atarget
DB01017MinocyclineCaspase-1target
DB01017MinocyclineCaspase-3target
DB01017MinocyclineCytochrome ctarget
DB01017MinocyclineSolute carrier family 22 member 6transporter
DB01017MinocyclineSolute carrier family 22 member 8transporter
DB01017MinocyclineSolute carrier family 22 member 11transporter
DB01017MinocyclineSolute carrier family 22 member 7transporter
DB00607NafcillinCytochrome P450 1A2enzyme
DB00607NafcillinCytochrome P450 3A4enzyme
DB00607NafcillinSolute carrier family 22 member 6transporter
DB00607NafcillinPenicillin-binding protein 1btarget
DB00607NafcillinPenicillin-binding protein 2Btarget
DB00607NafcillinPenicillin-binding protein 2atarget
DB00607NafcillinPenicillin-binding protein 3target
DB00607NafcillinPenicillin-binding protein 1Atarget
DB00607NafcillinSerum albumincarrier
DB00994Neomycin30S ribosomal protein S12target
DB00994Neomycin16S rRNAtarget
DB00994NeomycinExtracellular calcium-sensing receptortarget
DB01165OfloxacinDNA gyrase subunit Atarget
DB01165OfloxacinDNA topoisomerase 4 subunit Atarget
DB01165OfloxacinDNA topoisomerase 2-alphatarget
DB01165OfloxacinCytochrome P450 1A2enzyme
DB01165OfloxacinSolute carrier family 22 member 5transporter
DB01165OfloxacinMultidrug resistance-associated protein 1transporter
DB01165OfloxacinSolute carrier family 22 member 6transporter
DB01165OfloxacinCanalicular multispecific organic anion transporter 1transporter
DB01165OfloxacinSolute carrier family 22 member 4transporter
DB00417PhenoxymethylpenicillinPenicillin-binding protein 1Atarget
DB00417PhenoxymethylpenicillinMecA PBP2' (penicillin binding protein 2')target
DB00417PhenoxymethylpenicillinD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00417PhenoxymethylpenicillinPenicillin acylasetarget
DB00417PhenoxymethylpenicillinSolute carrier family 15 member 1target
DB00781Polymyxin B SulfateBacterial outer membranetarget
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidCytochrome P450 2C9enzyme
DB01032ProbenecidCytochrome P450 2C19enzyme
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidTaste receptor type 2 member 16target
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01369Quinupristin23S rRNAtarget
DB01369Quinupristin50S ribosomal protein L10target
DB01369Quinupristin50S ribosomal protein L22target
DB01369QuinupristinCytochrome P450 3A4enzyme
DB01220RifaximinDNA-directed RNA polymerase subunit betatarget
DB01220RifaximinNuclear receptor subfamily 1 group I member 2target
DB01220RifaximinCytochrome P450 3A4enzyme
DB06145SpiramycinCytochrome P450 3A4enzyme
DB06145Spiramycin50S ribosomal protein L3target
DB01082Streptomycin30S ribosomal protein S12target
DB01082Streptomycin16S rRNAtarget
DB01082StreptomycinSolute carrier family 22 member 6transporter
DB01082StreptomycinProtein-arginine deiminase type-4target
DB09324SulbactamBeta-lactamasetarget
DB01015SulfamethoxazoleBifunctional protein FolCtarget
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB00759Tetracycline16S rRNAtarget
DB00759TetracyclineMajor prion proteintarget
DB00759TetracyclineSerum albumincarrier
DB00759TetracyclineCytochrome P450 3A4enzyme
DB00759TetracyclineSolute carrier family 22 member 6transporter
DB00759TetracyclineSolute carrier family 22 member 8transporter
DB00759TetracyclineSolute carrier family 22 member 11transporter
DB00759TetracyclineSolute carrier family 22 member 7transporter
DB00759Tetracycline30S ribosomal protein S3target
DB00759Tetracycline30S ribosomal protein S8target
DB00759Tetracycline30S ribosomal protein S19target
DB00759Tetracycline30S ribosomal protein S14target
DB00759Tetracycline30S ribosomal protein S7target
DB00759TetracyclineMultidrug translocase MdfAtarget
DB00759TetracyclineProtein-arginine deiminase type-4target
DB00560Tigecycline30S ribosomal protein S9target
DB00560Tigecycline16S rRNAtarget
DB00560Tigecycline30S ribosomal protein S14target
DB00560Tigecycline30S ribosomal protein S13target
DB00560Tigecycline30S ribosomal protein S19target
DB00560Tigecycline30S ribosomal protein S12target
DrugDrug NamePhaseStatusCount
DB01060Amoxicillin1Completed1
DB09060Avibactam1Completed1
DB00207Azithromycin1Completed3
DB00355Aztreonam1Completed1
DB13028Biapenem1Completed1
DB00493Cefotaxime1Completed1
DB04918Ceftobiprole1Recruiting1
DB00537Ciprofloxacin1Completed1
DB01211Clarithromycin1Completed1
DB01190Clindamycin1Active Not Recruiting1
DB01190Clindamycin1Completed1
DB06219Dalbavancin1Completed2
DB06219Dalbavancin1Recruiting1
DB00250Dapsone1Completed1
DB06211Doripenem1Completed1
DB00254Doxycycline1Completed1
DB11744Epetraborole1Completed1
DB00301Flucloxacillin1Completed1
DB00196Fluconazole1Completed1
DB12134Gepotidacin1Completed4
DB01167Itraconazole1Completed1
DB11912Lanopepden1Completed5
DB11912Lanopepden1Terminated1
DB11912Lanopepden1Withdrawn2
DB01627Lincomycin1Completed1
DB00601Linezolid1Completed1
DB00601Linezolid1Withdrawn1
DB00760Meropenem1Recruiting1
DB00916Metronidazole1Active Not Recruiting1
DB00916Metronidazole1Completed2
DB00683Midazolam1Completed1
DB00218Moxifloxacin1Completed1
DB00218Moxifloxacin1Withdrawn2
DB11589Neon1Withdrawn1
DB00213Pantoprazole1Completed1
DB00615Rifabutin1Completed1
DB09308Solithromycin1Completed2
DB01015Sulfamethoxazole1Active Not Recruiting1
DB09042Tedizolid Phosphate1Completed3
DB00440Trimethoprim1Active Not Recruiting1
DB12107Vaborbactam1Completed3
DB12107Vaborbactam1Recruiting1
DB00582Voriconazole1Completed1
DB01117Atovaquone2Completed1
DB00207Azithromycin2Completed1
DB00355Aztreonam2Completed1
DB12430BC-37812Completed1
DB12997Brilacidin2Completed1
DB06590Ceftaroline fosamil2Completed1
DB01597Cilastatin2Completed1
DB00080Daptomycin2Completed1
DB06211Doripenem2Completed1
DB12134Gepotidacin2Completed1
DB01598Imipenem2Completed1
DB00601Linezolid2Completed3
DB12796MRX-I2Completed1
DB01256Retapamulin2Completed1
DB00560Tigecycline2Completed1
DB00512Vancomycin2Completed2
DB01593Zinc2 / 3Completed1
DB00355Aztreonam3Completed1
DB06590Ceftaroline fosamil3Completed2
DB00878Chlorhexidine3Active Not Recruiting1
DB00878Chlorhexidine3Recruiting1
DB01597Cilastatin3Completed1
DB00537Ciprofloxacin3Completed2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed1
DB01111Colistimethate3Completed1
DB06219Dalbavancin3Recruiting1
DB00485Dicloxacillin3Completed1
DB00303Ertapenem3Completed1
DB00798Gentamicin3Unknown Status1
DB01598Imipenem3Completed1
DB01137Levofloxacin3Completed2
DB00601Linezolid3Completed5
DB13887Meningococcal Polysaccharide Vaccine Group W-1353Completed1
DB13888Meningococcal Polysaccharide Vaccine Group Y3Completed1
DB13889Meningococcal group A polysaccharide3Completed1
DB13890Meningococcal group C polysaccharide3Completed3
DB00760Meropenem3Terminated1
DB12455Omadacycline3Completed2
DB00713Oxacillin3Completed1
DB10276Rotavirus Vaccine3Completed1
DB10303Rotavirus Vaccine3Completed3
DB10803Salmonella typhi ty2 vi polysaccharide antigen3Completed1
DB09153Sodium Chloride3Completed1
DB10293Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria crm197 protein conjugate antigen3Completed2
DB09042Tedizolid Phosphate3Completed1
DB00560Tigecycline3Completed2
DB00684Tobramycin3Completed1
DB00512Vancomycin3Completed2
DB01060Amoxicillin4Terminated1
DB00207Azithromycin4Completed3
DB01140Cefadroxil4Completed1
DB01327Cefazolin4Completed1
DB00878Chlorhexidine4Recruiting1
DB00766Clavulanate4Terminated1
DB01190Clindamycin4Completed1
DB06219Dalbavancin4Recruiting1
DB01075Diphenhydramine4Completed1
DB06211Doripenem4Completed1
DB00254Doxycycline4Completed1
DB00760Meropenem4Completed1
DB01017Minocycline4Recruiting1
DB00218Moxifloxacin4Completed3
DB00218Moxifloxacin4Terminated1
DB05336Obiltoxaximab4Not Yet Recruiting1
DB00319Piperacillin4Completed3
DB06812Povidone-iodine4Recruiting1
DB01129Rabeprazole4Completed1
DB08902Raxibacumab4Completed1
DB01606Tazobactam4Completed3
DB01593Zinc4Completed1
DB01212CeftriaxoneNot AvailableNot Yet Recruiting1
DB00080DaptomycinNot AvailableCompleted1
DB00301FlucloxacillinNot AvailableRecruiting1
DB00760MeropenemNot AvailableNot Yet Recruiting1
DB12343TemocillinNot AvailableNot Yet Recruiting2
DB00560TigecyclineNot AvailableRecruiting1