Showing BioInteractions for Etoperidone (DB09194)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 6
Transporter Mediated Interactions 3

	Interacting Group	Interacting Drugs
	Etoperidone is a Alpha-1 adrenergic receptors antagonist
1	Alpha-1 adrenergic receptors antagonists	Amoxapine, Arotinolol, Desipramine, Dosulepin, Labetalol, Lorpiprazole, Maprotiline, Mianserin, Mirtazapine, Perospirone, Pipamperone, Prochlorperazine, Quetiapine, Ranolazine, Tiapride
2	Alpha-1 adrenergic receptors inhibitors	Carvedilol, Chlorpromazine, Escitalopram
3	Alpha-1 adrenergic receptors agonists	Dobutamine, Tizanidine
4	Alpha-1 adrenergic receptors partial agonists	Buspirone
5	Alpha-1 adrenergic receptors binders	Paroxetine

	Interacting Group	Interacting Drugs
	Etoperidone is a Alpha-2 adrenergic receptors antagonist
1	Alpha-2 adrenergic receptors agonists	Bethanidine, Levonordefrin, Pergolide, Tizanidine, Xylazine
2	Alpha-2 adrenergic receptors inhibitors	Chlorpromazine, Escitalopram
3	Alpha-2 adrenergic receptors antagonists	Amoxapine, Cirazoline, Dosulepin, Esmirtazapine, Lorpiprazole, Maprotiline, Nortriptyline, Prochlorperazine, Setiptiline, Tiapride
4	Alpha-2 adrenergic receptors binders	Desipramine, Paroxetine
5	Alpha-2 adrenergic receptors stimulators	Tramadol

	Interacting Group	Interacting Drugs
	Etoperidone is a Dopamine D2 receptor antagonist
1	Dopamine D2 receptor agonists	Amantadine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cariprazine, Dihydro-alpha-ergocryptine, Dopamine, Ergotamine, Ketamine, Lamotrigine, Levodopa, Lisuride, Memantine, Minaprine, Pergolide, Pramipexole, Quinagolide, Ropinirole, Rotigotine
2	Dopamine D2 receptor antagonists	Acepromazine, Acetophenazine, Alizapride, Amisulpride, Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Bromopride, Buspirone, Carphenazine, Chlorpromazine, Chlorprothixene, Clozapine, Domperidone, Droperidol, Flupentixol, Fluphenazine, Fluspirilene, Haloperidol, Iloperidone, JNJ-37822681, Loxapine, Lurasidone, Melperone, Memantine, Mesoridazine, Methotrimeprazine, Metoclopramide, Mianserin, Molindone, Nortriptyline, Olanzapine, Paliperidone, Perospirone, Perphenazine, Pimozide, Pipamperone, Pipotiazine, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Raclopride, Remoxipride, Risperidone, Sertindole, Sulpiride, Tetrahydropalmatine, Thiethylperazine, Thioproperazine, Thioridazine, Thiothixene, Trifluoperazine, Triflupromazine, YKP-1358, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
3	Dopamine D2 receptor partial agonists	Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Cariprazine, Ketamine, Lumateperone, Sarizotan
4	Dopamine D2 receptor inhibitors	Escitalopram, Lamotrigine, Tetrabenazine
5	Dopamine D2 receptor binders	Amphetamine, Desipramine, Imipramine, Maprotiline
6	Dopamine D2 receptor blockers	Tiapride

	Interacting Group	Interacting Drugs
	Etoperidone is a Muscarinic acetylcholine receptor antagonist
1	Muscarinic acetylcholine receptor antagonists	Amoxapine, Doxylamine, Metixene, Nortriptyline, Propiomazine, Revefenacin
2	Muscarinic acetylcholine receptor binders	Cinnarizine, Ketamine, Meperidine, Trimipramine
3	Muscarinic acetylcholine receptor ligands	Amitriptyline
4	Muscarinic acetylcholine receptor inhibitors	Paroxetine

	Interacting Group	Interacting Drugs
	Etoperidone is a 5-hydroxytryptamine receptor 2A antagonist
1	5-hydroxytryptamine receptor 2A antagonists	Acepromazine, Amisulpride, Amitriptyline, Amoxapine, Amperozide, Aripiprazole, Aripiprazole lauroxil, Asenapine, Blonanserin, Brexpiprazole, Butriptyline, Cariprazine, Chlorpromazine, Chlorprothixene, Cinitapride, Clomipramine, Clozapine, Cyclobenzaprine, Cyproheptadine, Deramciclane, Desipramine, Dosulepin, Doxepin, Epinastine, Flibanserin, Flupentixol, Fluspirilene, Iloperidone, Imipramine, Lorpiprazole, Loxapine, Lumateperone, Lurasidone, Mesoridazine, Methotrimeprazine, Methysergide, Mianserin, Minaprine, Mirtazapine, Molindone, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Pipotiazine, Pizotifen, Promazine, Propiomazine, Quetiapine, Risperidone, Sertindole, Tegaserod, Thioproperazine, Thioridazine, Thiothixene, Trazodone, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
2	5-hydroxytryptamine receptor 2A partial agonists	4-Bromo-2,5-dimethoxyphenethylamine, Aripiprazole
3	5-hydroxytryptamine receptor 2A agonists	2,5-Dimethoxy-4-ethylthioamphetamine, 5-methoxy-N,N-dimethyltryptamine, Apomorphine, Bromocriptine, Cabergoline, Cannabidiol, Cisapride, Ergotamine, Fenfluramine, Lisuride, Midomafetamine, MMDA, N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine, Paroxetine, Pergolide, Pipamperone, Trimipramine, Zolmitriptan
4	5-hydroxytryptamine receptor 2A inducers	Donepezil
5	5-hydroxytryptamine receptor 2A inverse agonists	Ketanserin, Perospirone, Pimavanserin, Ritanserin, Sarpogrelate
6	5-hydroxytryptamine receptor 2A binders	Maprotiline
7	5-hydroxytryptamine receptor 2A inhibitors	Escitalopram, Lamotrigine

	Interacting Group	Interacting Drugs
	Etoperidone is a 5-hydroxytryptamine receptor 2C agonist
1	5-hydroxytryptamine receptor 2C agonists	2,5-Dimethoxy-4-ethylthioamphetamine, Apomorphine, Bromocriptine, Cabergoline, Dexfenfluramine, Ergotamine, Fenfluramine, Lisuride, Lofexidine, m-Chlorophenylpiperazine, Midomafetamine, Pergolide, Trazodone
2	5-hydroxytryptamine receptor 2C antagonists	Agomelatine, Amitriptyline, Amoxapine, Aripiprazole, Asenapine, Captodiame, Clomipramine, Clozapine, Cyclobenzaprine, Cyproheptadine, Doxepin, Fluoxetine, Imipramine, Lorpiprazole, Loxapine, Methotrimeprazine, Methysergide, Mianserin, Minaprine, Mirtazapine, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Pizotifen, Promazine, Propiomazine, Risperidone, Sertindole, Tegaserod, Tramadol, Trimipramine, Yohimbine, Ziprasidone
3	5-hydroxytryptamine receptor 2C ligands	Quetiapine
4	5-hydroxytryptamine receptor 2C inverse agonists	Deramciclane
5	5-hydroxytryptamine receptor 2C partial agonists	4-Bromo-2,5-dimethoxyphenethylamine, Aripiprazole
6	5-hydroxytryptamine receptor 2C binders	Chlorpromazine, Desipramine, Imipramine, Maprotiline
7	5-hydroxytryptamine receptor 2C inhibitors	Escitalopram

	Interacting Group	Interacting Drugs
	Etoperidone is a Sodium-dependent serotonin transporter inhibitor
1	Sodium-dependent serotonin transporter inhibitors	4-Methoxyamphetamine, Amitriptyline, Amoxapine, Benzatropine, Butriptyline, Chlorpheniramine, Citalopram, Clomipramine, Cocaine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexfenfluramine, Dexmethylphenidate, Dextromethorphan, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Fenfluramine, Fluoxetine, Fluvoxamine, Imipramine, Levomilnacipran, Lumateperone, Mazindol, Mianserin, Milnacipran, Minaprine, Mirtazapine, Nefazodone, Nortriptyline, Paroxetine, Phentermine, Procaine, Protriptyline, Pseudoephedrine, Sertraline, Sibutramine, Tapentadol, Tegaserod, Tramadol, Trazodone, Trimipramine, Venlafaxine, Vilazodone, Vortioxetine
2	Sodium-dependent serotonin transporter binders	Amphetamine, Atomoxetine, Loxapine, Sertraline
3	Sodium-dependent serotonin transporter negative modulators	Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
4	Sodium-dependent serotonin transporter substrates	Fenfluramine, Mirtazapine, Tegaserod
5	Sodium-dependent serotonin transporter bindings	Meperidine
6	Sodium-dependent serotonin transporter antagonists	Butriptyline, Lorpiprazole, Zotepine
7	Sodium-dependent serotonin transporter modulators	Aripiprazole

	Interacting Group	Interacting Drugs
	Etoperidone is a Sodium-dependent noradrenaline transporter inhibitor
1	Sodium-dependent noradrenaline transporter inhibitors	Amitriptyline, Amoxapine, Atomoxetine, Benzatropine, Bupropion, Chlorpheniramine, Clomipramine, Cocaine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextromethorphan, Diethylpropion, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Ginkgo biloba, Imipramine, Ketamine, Levomilnacipran, Maprotiline, Mazindol, Meperidine, Methylphenidate, Mianserin, Milnacipran, Nefazodone, Netarsudil, Nortriptyline, Orphenadrine, Paroxetine, Phenmetrazine, Phentermine, Procaine, Protriptyline, Pseudoephedrine, Rauwolfia serpentina root, Reboxetine, Sertraline, Sibutramine, Tapentadol, Tramadol, Trimipramine, Venlafaxine, Viloxazine
2	Sodium-dependent noradrenaline transporter partial agonists	Guanadrel
3	Sodium-dependent noradrenaline transporter inducers	Debrisoquine, Guanethidine
4	Sodium-dependent noradrenaline transporter negative modulators	Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA, Phendimetrazine
5	Sodium-dependent noradrenaline transporter inverse agonists	Ephedrine
6	Sodium-dependent noradrenaline transporter substrates	Droxidopa, Iobenguane, Iobenguane sulfate I-123, Norepinephrine, Nortriptyline
7	Sodium-dependent noradrenaline transporter binders	Loxapine
8	Sodium-dependent noradrenaline transporter stimulators	Amphetamine
9	Sodium-dependent noradrenaline transporter blockers	Vortioxetine
10	Sodium-dependent noradrenaline transporter antagonists	Zotepine

	Interacting Group	Interacting Drugs
	Etoperidone is a Sodium-dependent dopamine transporter inhibitor
1	Sodium-dependent dopamine transporter inhibitors	4-Methoxyamphetamine, Armodafinil, Benzatropine, Benzphetamine, Bupropion, Chloroprocaine, Chlorpheniramine, Cocaine, Desvenlafaxine, Dexmethylphenidate, Diethylpropion, Diphenylpyraline, Duloxetine, Escitalopram, Fencamfamin, Imipramine, Mazindol, Meperidine, Methylphenidate, Modafinil, Nefazodone, Phenmetrazine, Phentermine, Procaine, Pseudoephedrine, Sertraline, Sibutramine, Trimipramine, Venlafaxine
2	Sodium-dependent dopamine transporter negative modulators	Amphetamine, Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
3	Sodium-dependent dopamine transporter binders	Amoxapine, Loxapine, Mianserin, Sertraline
4	Sodium-dependent dopamine transporter inducers	Dopamine
5	Sodium-dependent dopamine transporter antagonists	Armodafinil
6	Sodium-dependent dopamine transporter modulators	Aripiprazole