Also known as: Relapsing-Remitting MS / Relapse-Remitting Multiple Sclerosis / Relapse Remitting Multiple Sclerosis / Relapsing-Remitting Multiple Sclerosis / Multiple Sclerosis, Relapsing, Remitting / Multiple Sclerosis (Relapsing Remitting) / Multiple Sclerosis (MS) - Relapsing-remitting / Relapsing Remitting Multiple Sclerosis / Multiple Sclerosis - Relapsing Remitting / Relapsing Remitting MS / Relapsing Remitting MS (RRMS) / Remitting-Relapsing Multiple Sclerosis / Relapsing Remitting Multiple Sclerosis (RRMS) / Relapsing/remitting Multiple sclerosis / Multiple Sclerosis, Relapsing Remitting / Multiple Sclerosis, Relapsing-Remitting / Relapsing, Remitting Multiple Sclerosis / Relapsing-Remitting Multiple Sclerosis (RRMS) / Multiple Sclerosis-Relapsing-Remitting
DrugDrug NameDrug Description
DB00087AlemtuzumabHumanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein,CD52. The Campath-1H antibody is an IgG1 kappa with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G). Campath is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.
DB00060Interferon beta-1aHuman interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
DB00068Interferon beta-1bHuman interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
DB01204MitoxantroneAn anthracenedione-derived antineoplastic agent. [PubChem]
DB00108NatalizumabHumanized IgG4k monoclonal antibody produced in murine myeloma cells. Natalizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to a4-integrin. Natalizumab was voluntarily withdrawn from U.S. market because of risk of Progressive multifocal leukoencephalopathy (PML). It was returned to market July, 2006.
DrugDrug NameTargetType
DB00087AlemtuzumabCAMPATH-1 antigentarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00087AlemtuzumabComplement C1r subcomponenttarget
DB00087AlemtuzumabComplement C1q subcomponent subunit Atarget
DB00087AlemtuzumabComplement C1q subcomponent subunit Btarget
DB00087AlemtuzumabComplement C1q subcomponent subunit Ctarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00087AlemtuzumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00087AlemtuzumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00060Interferon beta-1aInterferon alpha/beta receptor 1target
DB00060Interferon beta-1aInterferon alpha/beta receptor 2target
DB00068Interferon beta-1bInterferon alpha/beta receptor 1target
DB00068Interferon beta-1bInterferon alpha/beta receptor 2target
DB01204MitoxantroneDNA topoisomerase 2-alphatarget
DB01204MitoxantroneCytochrome P450 2E1enzyme
DB01204MitoxantroneMultidrug resistance protein 1transporter
DB01204MitoxantroneMultidrug resistance-associated protein 1transporter
DB01204MitoxantroneATP-binding cassette sub-family G member 2transporter
DB01204MitoxantroneDNAtarget
DB01204MitoxantroneCytochrome P450 1B1enzyme
DB01204MitoxantroneCytochrome P450 3A4enzyme
DB00108NatalizumabIntegrin alpha-4target
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00108NatalizumabComplement C1r subcomponenttarget
DB00108NatalizumabComplement C1q subcomponent subunit Atarget
DB00108NatalizumabComplement C1q subcomponent subunit Btarget
DB00108NatalizumabComplement C1q subcomponent subunit Ctarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00108NatalizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00108NatalizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00108NatalizumabIntercellular adhesion molecule 1target
DrugDrug NamePhaseStatusCount
DB01281Abatacept1Completed1
DB00173Adenine1Completed2
DB08868Fingolimod1Completed1
DB00629Guanabenz1Recruiting1
DB00060Interferon beta-1a1Completed2
DB00060Interferon beta-1a1Recruiting1
DB00128L-Aspartic Acid1Completed2
DB00120L-Phenylalanine1Completed1
DB00279Liothyronine1Active Not Recruiting1
DB00422Methylphenidate1Unknown Status1
DB00108Natalizumab1Completed2
DB01132Pioglitazone1Completed1
DB05185TRO196221Completed1
DB05767Andrographolide1 / 2Completed1
DB01598Imipenem1 / 2Terminated1
DB00877Sirolimus1 / 2Terminated1
DB01281Abatacept2Completed1
DB00087Alemtuzumab2Completed1
DB00262Carmustine2Completed1
DB00283Clemastine2Completed1
DB00987Cytarabine2Completed1
DB00111Daclizumab2Completed2
DB08908Dimethyl fumarate2Completed2
DB08908Dimethyl fumarate2Recruiting1
DB01184Domperidone2Enrolling by Invitation1
DB00783Estradiol2Completed1
DB04573Estriol2Completed1
DB04573Estriol2Recruiting1
DB00773Etoposide2Completed1
DB06623Flupirtine2Terminated1
DB05259Glatiramer Acetate2Completed5
DB05259Glatiramer Acetate2Terminated1
DB00062Human Serum Albumin2Completed1
DB00028Immune Globulin Human2Completed1
DB04335Inosine2Completed1
DB00060Interferon beta-1a2Active Not Recruiting1
DB00060Interferon beta-1a2Completed3
DB00060Interferon beta-1a2Not Yet Recruiting1
DB00060Interferon beta-1a2Withdrawn1
DB00068Interferon beta-1b2Completed1
DB00555Lamotrigine2Unknown Status1
DB06685Laquinimod2Active Not Recruiting1
DB06685Laquinimod2Completed1
DB01065Melatonin2Completed1
DB01042Melphalan2Completed1
DB00959Methylprednisolone2Active Not Recruiting1
DB00959Methylprednisolone2Completed1
DB01017Minocycline2Terminated1
DB01204Mitoxantrone2Completed1
DB01204Mitoxantrone2Terminated1
DB00108Natalizumab2Completed4
DB00717Norethisterone2Recruiting1
DB11988Ocrelizumab2Active Not Recruiting1
DB00635Prednisone2Completed1
DB06817Raltegravir2Completed1
DB09029Secukinumab2Completed1
DB09325Sodium fluoride2Completed1
DB06287Temsirolimus2Completed1
DB00624Testosterone2Withdrawn1
DB02891Tricyclazole2Completed1
DB09145Water2Completed1
DB08908Dimethyl fumarate2 / 3Recruiting1
DB08868Fingolimod2 / 3Recruiting1
DB05259Glatiramer Acetate2 / 3Recruiting1
DB00060Interferon beta-1a2 / 3Recruiting1
DB00068Interferon beta-1b2 / 3Recruiting1
DB04921MBP82982 / 3Completed1
DB00108Natalizumab2 / 3Recruiting1
DB11133Omega-3 fatty acids2 / 3Completed1
DB00087Alemtuzumab3Active Not Recruiting1
DB00087Alemtuzumab3Completed3
DB00169Cholecalciferol3Recruiting1
DB00242Cladribine3Completed2
DB01285Corticotropin3Recruiting1
DB00111Daclizumab3Active Not Recruiting1
DB00111Daclizumab3Completed1
DB00111Daclizumab3Not Yet Recruiting1
DB06637Dalfampridine3Completed1
DB08908Dimethyl fumarate3Active Not Recruiting4
DB08908Dimethyl fumarate3Completed3
DB08908Dimethyl fumarate3Recruiting3
DB08908Dimethyl fumarate3Withdrawn1
DB08868Fingolimod3Completed1
DB08868Fingolimod3Terminated1
DB08868Fingolimod3Withdrawn1
DB05259Glatiramer Acetate3Active Not Recruiting1
DB05259Glatiramer Acetate3Completed7
DB05259Glatiramer Acetate3Terminated2
DB00060Interferon beta-1a3Active Not Recruiting2
DB00060Interferon beta-1a3Completed6
DB00060Interferon beta-1a3Recruiting1
DB00060Interferon beta-1a3Terminated1
DB00060Interferon beta-1a3Withdrawn1
DB00068Interferon beta-1b3Completed2
DB06685Laquinimod3Withdrawn1
DB00742Mannitol3Completed1
DB00959Methylprednisolone3Unknown Status1
DB00788Naproxen3Completed1
DB00108Natalizumab3Completed3
DB00108Natalizumab3Terminated2
DB11988Ocrelizumab3Active Not Recruiting2
DB11988Ocrelizumab3Recruiting3
DB09122Peginterferon beta-1a3Completed1
DB00175Pravastatin3Completed1
DB00073Rituximab3Recruiting1
DB00641Simvastatin3Completed1
DB00641Simvastatin3Unknown Status1
DB00641Simvastatin3Withdrawn1
DB09153Sodium Chloride3Recruiting1
DB09153Sodium Chloride3Terminated1
DB09145Water3Recruiting1
DB00316Acetaminophen4Completed1
DB00945Acetylsalicylic acid4Completed1
DB00787Aciclovir4Completed1
DB00087Alemtuzumab4Completed1
DB00087Alemtuzumab4Recruiting1
DB00484Brimonidine4Withdrawn1
DB00341Cetirizine4Completed1
DB00215Citalopram4Terminated1
DB01285Corticotropin4Recruiting1
DB09547Corticotropin4Recruiting1
DB08908Dimethyl fumarate4Active Not Recruiting1
DB08908Dimethyl fumarate4Completed2
DB08908Dimethyl fumarate4Not Yet Recruiting1
DB08908Dimethyl fumarate4Recruiting2
DB08908Dimethyl fumarate4Withdrawn3
DB00736Esomeprazole4Completed1
DB08868Fingolimod4Active Not Recruiting1
DB08868Fingolimod4Completed6
DB08868Fingolimod4Recruiting2
DB08868Fingolimod4Terminated3
DB08868Fingolimod4Unknown Status1
DB00472Fluoxetine4Terminated1
DB05259Glatiramer Acetate4Active Not Recruiting1
DB05259Glatiramer Acetate4Completed3
DB05259Glatiramer Acetate4Terminated3
DB01050Ibuprofen4Completed1
DB00060Interferon beta-1a4Completed13
DB00060Interferon beta-1a4Terminated3
DB00060Interferon beta-1a4Withdrawn2
DB00068Interferon beta-1b4Completed4
DB00068Interferon beta-1b4Terminated2
DB00836Loperamide4Terminated1
DB00563Methotrexate4Completed1
DB00959Methylprednisolone4Completed4
DB00108Natalizumab4Completed4
DB00108Natalizumab4Terminated1
DB00108Natalizumab4Unknown Status1
DB00108Natalizumab4Withdrawn1
DB09122Peginterferon beta-1a4Recruiting1
DB09122Peginterferon beta-1a4Withdrawn1
DB00635Prednisone4Terminated1
DB00863Ranitidine4Completed1
DB09512Simethicone4Terminated1
DB09153Sodium Chloride4Completed4
DB09153Sodium Chloride4Terminated1
DB09153Sodium Chloride4Withdrawn1
DB00285Venlafaxine4Terminated1
DB00162Vitamin A4Unknown Status1
DB09145Water4Terminated1
DB01285CorticotropinNot AvailableRecruiting1
DB01285CorticotropinNot AvailableUnknown Status1
DB09547CorticotropinNot AvailableUnknown Status1
DB08908Dimethyl fumarateNot AvailableActive Not Recruiting1
DB08908Dimethyl fumarateNot AvailableCompleted1
DB08908Dimethyl fumarateNot AvailableTerminated1
DB00402EszopicloneNot AvailableCompleted1
DB09150Fludeoxyglucose F-18Not AvailableRecruiting1
DB00060Interferon beta-1aNot AvailableActive Not Recruiting1
DB00060Interferon beta-1aNot AvailableCompleted4
DB00068Interferon beta-1bNot AvailableCompleted6
DB00068Interferon beta-1bNot AvailableRecruiting1
DB00068Interferon beta-1bNot AvailableWithdrawn1
DB00745ModafinilNot AvailableUnknown Status1
DB00108NatalizumabNot AvailableActive Not Recruiting3
DB00108NatalizumabNot AvailableCompleted2
DB00108NatalizumabNot AvailableRecruiting1
DB09153Sodium ChlorideNot AvailableCompleted3
DB08880TeriflunomideNot AvailableEnrolling by Invitation1