Showing BioInteractions for Glycyrrhizic acid (DB13751)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 4
Transporter Mediated Interactions 1

	Interacting Group	Interacting Drugs
	Glycyrrhizic acid is a Corticosteroid 11-beta-dehydrogenase isozyme 1 antagonist
1	Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitors	Carbenoxolone, Somapacitan
2	Corticosteroid 11-beta-dehydrogenase isozyme 1 substrates	Dexamethasone, Dexamethasone acetate, Fludrocortisone, Hydrocortisone, Nabumetone, Prednisolone phosphate, Prednisone

	Interacting Group	Interacting Drugs
	Glycyrrhizic acid is a Tumor necrosis factor antagonist
1	Tumor necrosis factor inhibitors	Amrinone, Chloroquine, Infliximab, Polaprezinc, Pomalidomide, Pseudoephedrine, Thalidomide
2	Tumor necrosis factor neutralizers	Certolizumab pegol
3	Tumor necrosis factor antagonists	Epinephrine
4	Tumor necrosis factor agonists	Epinephrine, Foreskin fibroblast (neonatal), Foreskin keratinocyte (neonatal)
5	Tumor necrosis factor inducers	Bryostatin 1

	Interacting Group	Interacting Drugs
	Glycyrrhizic acid is a Caspase-3 antagonist
1	Caspase-3 negative modulators	Minocycline
2	Caspase-3 inhibitors	Acetylsalicylic acid
3	Caspase-3 activators	Incadronic acid

	Interacting Group	Interacting Drugs
	Glycyrrhizic acid is a Lipoprotein lipase inducer
1	Lipoprotein lipase inhibitors	Semaglutide, Tyloxapol
2	Lipoprotein lipase stimulators	Omega-3-carboxylic acids

	Interacting Group	Interacting Drugs
	Glycyrrhizic acid is a Bile salt export pump substrate
1	Bile salt export pump inhibitors	Amiodarone, Bosentan, Celecoxib, Chlorpromazine, Cholic Acid, Cimetidine, Clotrimazole, Cyclosporine, Erythromycin, Ethinylestradiol, Fusidic acid, Glyburide, Glycochenodeoxycholic Acid, Ketoconazole, Lenvatinib, Letermovir, Lopinavir, Nifedipine, Obeticholic acid, Olmesartan, Paclitaxel, Pralsetinib, Progesterone, Quinidine, Remdesivir, Reserpine, Rifampicin, Ritonavir, Simeprevir, Sulfamethoxazole, Tamoxifen, Tipranavir, Troglitazone, Ursodeoxycholic acid, Valinomycin, Vinblastine
2	Bile salt export pump substrates	Amiodarone, Astemizole, Atazanavir, Atenolol, Atorvastatin, Atropine, Belantamab mafodotin, Benzbromarone, Budesonide, Cefaclor, Cerivastatin, Cholic Acid, Clarithromycin, Clotrimazole, Cyclosporine, Daunorubicin, Diclofenac, Diethylstilbestrol, Digoxin, Dihydroergocristine, Dipyridamole, Disulfiram, Doxorubicin, Efavirenz, Erythromycin, Ezetimibe, Felodipine, Fenofibrate, Flucloxacillin, Fluorescein, Fluvoxamine, Glimepiride, Glipizide, Glyburide, Glycochenodeoxycholic Acid, Imatinib, Indinavir, Indocyanine green acid form, Indomethacin, Isradipine, Loratadine, Losartan, Lovastatin, Mifepristone, Naproxen, Nefazodone, Nelfinavir, Nicardipine, Nitrendipine, Nitrofurantoin, Ofloxacin, Paclitaxel, Pilsicainide, Pitavastatin, Prasterone sulfate, Pravastatin, Ranolazine, Repaglinide, Rosiglitazone, Rosuvastatin, Saquinavir, Simvastatin, Spironolactone, Sulfinpyrazone, Taurocholic acid, Telmisartan, Terfenadine, Tinidazole, Tipranavir, Ursodeoxycholic acid, Vinblastine, Vincristine
3	Bile salt export pump inducers	Cholic Acid, Deoxycholic acid, Dexamethasone, Dexamethasone acetate, Obeticholic acid, Phenobarbital, Taurocholic acid, Ursodeoxycholic acid