Showing BioInteractions for Carphenazine (DB01038)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 3

	Interacting Group	Interacting Drugs
	Carphenazine is a Dopamine D1 receptor antagonist
1	Dopamine D1 receptor antagonists	Acepromazine, Amoxapine, Aripiprazole, Asenapine, Chlorpromazine, Chlorprothixene, Clozapine, Flupentixol, Fluphenazine, Haloperidol, Iloperidone, Lisuride, Loxapine, Methotrimeprazine, Methylergometrine, Olanzapine, Paliperidone, Periciazine, Perphenazine, Pipamperone, Pipotiazine, Quetiapine, Risperidone, Tetrahydropalmatine, Thioproperazine, Thioridazine, Thiothixene, Triflupromazine, Ziprasidone, Zuclopenthixol
2	Dopamine D1 receptor agonists	Apomorphine, Bromocriptine, Cabergoline, Dopamine, Fenoldopam, Levodopa, Minaprine, Pergolide, Rotigotine
3	Dopamine D1 receptor partial agonists	Aripiprazole, Phenylpropanolamine
4	Dopamine D1 receptor ligands	Aripiprazole

	Interacting Group	Interacting Drugs
	Carphenazine is a Dopamine D5 receptor antagonist
1	Dopamine D5 receptor agonists	Apomorphine, Bromocriptine, Cabergoline, Dopamine, Fenoldopam, Levodopa, Pergolide, Rotigotine
2	Dopamine D5 receptor antagonists	Aripiprazole, Lisuride, Methotrimeprazine, Olanzapine, Ziprasidone, Zuclopenthixol
3	Dopamine D5 receptor partial agonists	Aripiprazole
4	Dopamine D5 receptor ligands	Aripiprazole, Quetiapine
5	Dopamine D5 receptor inhibitors	Chlorpromazine
6	Dopamine D5 receptor binders	Loxapine

	Interacting Group	Interacting Drugs
	Carphenazine is a Dopamine D2 receptor antagonist
1	Dopamine D2 receptor agonists	Amantadine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cariprazine, Dihydro-alpha-ergocryptine, Dopamine, Ergotamine, Ketamine, Lamotrigine, Levodopa, Lisuride, Memantine, Minaprine, Pergolide, Pramipexole, Quinagolide, Ropinirole, Rotigotine
2	Dopamine D2 receptor antagonists	Acepromazine, Acetophenazine, Alizapride, Amisulpride, Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Bromopride, Buspirone, Chlorpromazine, Chlorprothixene, Clozapine, Domperidone, Droperidol, Etoperidone, Flupentixol, Fluphenazine, Fluspirilene, Haloperidol, Iloperidone, JNJ-37822681, Loxapine, Lurasidone, Melperone, Memantine, Mesoridazine, Methotrimeprazine, Metoclopramide, Mianserin, Molindone, Nortriptyline, Olanzapine, Paliperidone, Perospirone, Perphenazine, Pimozide, Pipamperone, Pipotiazine, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Raclopride, Remoxipride, Risperidone, Sertindole, Sulpiride, Tetrahydropalmatine, Thiethylperazine, Thioproperazine, Thioridazine, Thiothixene, Trifluoperazine, Triflupromazine, YKP-1358, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
3	Dopamine D2 receptor partial agonists	Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Cariprazine, Ketamine, Lumateperone, Sarizotan
4	Dopamine D2 receptor inhibitors	Escitalopram, Lamotrigine, Tetrabenazine
5	Dopamine D2 receptor binders	Amphetamine, Desipramine, Imipramine, Maprotiline
6	Dopamine D2 receptor blockers	Tiapride