Acute Myocardial Infarction (AMI)

Also known as: Acute Myocardial Infarctus / Acute Myocardial Infarct / Myocardial Infarction, Acute / Acute Myocardial Infarction / Acute myocardial infarction NOS / Acute transmural myocardial infarction of unspecified site / Acute myocardial infarction, unspecified site, episode of care unspecified / Acute myocardial infarction, unspecified site / Myocardial infarction acute

Drug	Drug Name	Drug Description
DB00009	Alteplase	A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
DB00758	Clopidogrel	An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB00722	Lisinopril	An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
DB00015	Reteplase	A purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.

Drug	Drug Name	Target	Type
DB00009	Alteplase	Urokinase plasminogen activator surface receptor	target
DB00009	Alteplase	Fibrinogen alpha chain	target
DB00009	Alteplase	Plasminogen	target
DB00009	Alteplase	Plasminogen activator inhibitor 1	target
DB00758	Clopidogrel	P2Y purinoceptor 12	target
DB00758	Clopidogrel	Cytochrome P450 3A4	enzyme
DB00758	Clopidogrel	Cytochrome P450 2B6	enzyme
DB00758	Clopidogrel	Cytochrome P450 3A5	enzyme
DB00758	Clopidogrel	Cytochrome P450 2C19	enzyme
DB00758	Clopidogrel	Cytochrome P450 2C9	enzyme
DB00758	Clopidogrel	Cytochrome P450 1A2	enzyme
DB00758	Clopidogrel	Cytochrome P450 2C8	enzyme
DB00758	Clopidogrel	Liver carboxylesterase 1	enzyme
DB00758	Clopidogrel	P-glycoprotein 1	transporter
DB00758	Clopidogrel	Solute carrier family 22 member 1	transporter
DB00758	Clopidogrel	Solute carrier family 22 member 2	transporter
DB00722	Lisinopril	Angiotensin-converting enzyme	target
DB00722	Lisinopril	Solute carrier family 15 member 1	transporter
DB00722	Lisinopril	Solute carrier family 15 member 2	transporter
DB00722	Lisinopril	Renin	target
DB00015	Reteplase	Fibrinogen alpha chain	target
DB00015	Reteplase	Plasminogen	target
DB00015	Reteplase	Plasminogen activator inhibitor 1	target

Drug	Drug Name	Phase	Status	Count
DB00264	Metoprolol	1	Completed	1
DB00683	Midazolam	1	Completed	1
DB00058	Alpha-1-proteinase inhibitor	1 / 2	Completed	1
DB00099	Filgrastim	1 / 2	Completed	1
DB00054	Abciximab	2	Active Not Recruiting	1
DB00026	Anakinra	2	Completed	1
DB14547	Chloride ion	2	Completed	1
DB00091	Cyclosporine	2	Withdrawn	1
DB11723	Dutogliptin	2	Enrolling by Invitation	1
DB00063	Eptifibatide	2	Unknown Status	1
DB00016	Erythropoietin	2	Completed	1
DB00016	Erythropoietin	2	Unknown Status	1
DB00099	Filgrastim	2	Completed	1
DB00099	Filgrastim	2	Enrolling by Invitation	1
DB05549	INO-1001	2	Completed	1
DB01065	Melatonin	2	Completed	1
DB01065	Melatonin	2	Terminated	1
DB09107	Methoxy polyethylene glycol-epoetin beta	2	Completed	1
DB04899	Nesiritide	2	Completed	1
DB00435	Nitric Oxide	2	Completed	1
DB00435	Nitric Oxide	2	Terminated	1
DB09152	Nitrogen	2	Terminated	1
DB09112	Nitrous acid	2	Completed	1
DB01098	Rosuvastatin	2	Unknown Status	1
DB15163	Selatogrel	2	Completed	1
DB01236	Sevoflurane	2	Completed	1
DB00641	Simvastatin	2	Unknown Status	1
DB09153	Sodium chloride	2	Recruiting	1
DB02772	Sucrose	2	Recruiting	1
DB00031	Tenecteplase	2	Completed	1
DB12003	Thymosin beta-4	2	Suspended	1
DB06151	Acetylcysteine	2 / 3	Completed	1
DB00945	Acetylsalicylic acid	2 / 3	Recruiting	1
DB00026	Anakinra	2 / 3	Completed	1
DB01394	Colchicine	2 / 3	Not Yet Recruiting	1
DB00254	Doxycycline	2 / 3	Active Not Recruiting	1
DB11242	Gelatin	2 / 3	Unknown Status	1
DB00123	L-Lysine	2 / 3	Recruiting	1
DB13144	Lenograstim	2 / 3	Unknown Status	1
DB01261	Sitagliptin	2 / 3	Unknown Status	1
DB00054	Abciximab	3	Terminated	1
DB06151	Acetylcysteine	3	Completed	1
DB00640	Adenosine	3	Completed	1
DB06605	Apixaban	3	Not Yet Recruiting	1
DB00006	Bivalirudin	3	Recruiting	1
DB00006	Bivalirudin	3	Terminated	1
DB00758	Clopidogrel	3	Completed	1
DB00091	Cyclosporine	3	Completed	1
DB00012	Darbepoetin alfa	3	Completed	1
DB09038	Empagliflozin	3	Recruiting	1
DB01225	Enoxaparin	3	Completed	1
DB08917	Ferric carboxymaltose	3	Recruiting	1
DB00569	Fondaparinux	3	Completed	1
DB01109	Heparin	3	Completed	2
DB01109	Heparin	3	Recruiting	1
DB01109	Heparin	3	Terminated	1
DB00028	Human immunoglobulin G	3	Completed	1
DB00295	Morphine	3	Completed	1
DB09140	Oxygen	3	Completed	1
DB04949	Pexelizumab	3	Completed	1
DB00178	Ramipril	3	Active Not Recruiting	1
DB09292	Sacubitril	3	Active Not Recruiting	1
DB01390	Sodium bicarbonate	3	Completed	1
DB00086	Streptokinase	3	Completed	1
DB08816	Ticagrelor	3	Completed	1
DB00775	Tirofiban	3	Completed	1
DB00177	Valsartan	3	Active Not Recruiting	1
DB00682	Warfarin	3	Not Yet Recruiting	1
DB00054	Abciximab	4	Completed	3
DB06151	Acetylcysteine	4	Completed	1
DB00945	Acetylsalicylic acid	4	Active Not Recruiting	1
DB00945	Acetylsalicylic acid	4	Completed	1
DB01076	Atorvastatin	4	Completed	2
DB01076	Atorvastatin	4	Recruiting	1
DB01393	Bezafibrate	4	Completed	1
DB00612	Bisoprolol	4	Recruiting	2
DB00006	Bivalirudin	4	Completed	1
DB06441	Cangrelor	4	Recruiting	1
DB01136	Carvedilol	4	Recruiting	1
DB01166	Cilostazol	4	Active Not Recruiting	2
DB00758	Clopidogrel	4	Active Not Recruiting	2
DB00758	Clopidogrel	4	Completed	3
DB00758	Clopidogrel	4	Terminated	2
DB00758	Clopidogrel	4	Withdrawn	1
DB01394	Colchicine	4	Recruiting	1
DB01394	Colchicine	4	Unknown Status	1
DB00343	Diltiazem	4	Completed	1
DB00016	Erythropoietin	4	Completed	1
DB00016	Erythropoietin	4	Unknown Status	1
DB00736	Esomeprazole	4	Completed	2
DB00973	Ezetimibe	4	Recruiting	1
DB00927	Famotidine	4	Completed	2
DB01109	Heparin	4	Completed	1
DB00159	Icosapent	4	Unknown Status	1
DB08887	Icosapent ethyl	4	Unknown Status	1
DB00047	Insulin glargine	4	Completed	1
DB00030	Insulin human	4	Completed	1
DB00046	Insulin lispro	4	Completed	1
DB01249	Iodixanol	4	Completed	1
DB09156	Iopromide	4	Completed	1
DB01233	Metoclopramide	4	Recruiting	1
DB00264	Metoprolol	4	Completed	1
DB00264	Metoprolol	4	Recruiting	2
DB00295	Morphine	4	Recruiting	1
DB04861	Nebivolol	4	Recruiting	1
DB00727	Nitroglycerin	4	Completed	1
DB00175	Pravastatin	4	Unknown Status	1
DB00015	Reteplase	4	Completed	2
DB09153	Sodium chloride	4	Recruiting	1
DB00086	Streptokinase	4	Completed	2
DB00031	Tenecteplase	4	Terminated	1
DB08816	Ticagrelor	4	Recruiting	2
DB08816	Ticagrelor	4	Terminated	1
DB00775	Tirofiban	4	Completed	4
DB00775	Tirofiban	4	Unknown Status	1
DB00661	Verapamil	4	Completed	1
DB00316	Acetaminophen	Not Available	Withdrawn	1
DB00945	Acetylsalicylic acid	Not Available	Active Not Recruiting	1
DB00945	Acetylsalicylic acid	Not Available	Completed	1
DB01076	Atorvastatin	Not Available	Active Not Recruiting	1
DB00796	Candesartan cilexetil	Not Available	Terminated	1
DB01136	Carvedilol	Not Available	Completed	1
DB00758	Clopidogrel	Not Available	Active Not Recruiting	1
DB00115	Cyanocobalamin	Not Available	Completed	1
DB01225	Enoxaparin	Not Available	Completed	1
DB00813	Fentanyl	Not Available	Completed	1
DB00158	Folic acid	Not Available	Completed	1
DB01109	Heparin	Not Available	Completed	1
DB10773	Influenza A virus A/California/7/2009 (H1N1) recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB14417	Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB14423	Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB10774	Influenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB14418	Influenza B virus B/Brisbane/60/2008 recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB10779	Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB10775	Influenza B virus B/Wisconsin/1/2010 recombinant hemagglutinin antigen	Not Available	Recruiting	1
DB06655	Liraglutide	Not Available	Recruiting	1
DB00295	Morphine	Not Available	Completed	1
DB09220	Nicorandil	Not Available	Completed	2
DB06209	Prasugrel	Not Available	Completed	1
DB00165	Pyridoxine	Not Available	Completed	1
DB09292	Sacubitril	Not Available	Recruiting	1
DB00966	Telmisartan	Not Available	Terminated	1
DB08816	Ticagrelor	Not Available	Active Not Recruiting	1
DB08816	Ticagrelor	Not Available	Completed	2
DB00177	Valsartan	Not Available	Recruiting	1