Acute Myocardial Infarction (AMI)

Also known as: Acute Myocardial Infarction / Myocardial Infarction, Acute / Acute myocardial infarction NOS / Acute transmural myocardial infarction of unspecified site / Acute myocardial infarction, unspecified site, episode of care unspecified / Acute myocardial infarction, unspecified site / Myocardial infarction acute

DrugDrug NameDrug Description
DB00009AlteplaseHuman tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells
DB00758ClopidogrelClopidogrel, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to inhibit blood clots in a variety of conditions such as peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Clopidogrel is sold under the name Plavix by Sanofi and Bristol-Myers Squibb. The drug is an irreversible inhibitor of the P2Y12 adenosine diphosphate receptor found on the membranes of platelet cells. Clopidogrel use is associated with several serious adverse drug reactions such as severe neutropenia, various forms of hemorrhage, and cardiovascular edema.
DB00722LisinoprilLisinopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Lisinopril may be used to treat hypertension and symptomatic congestive heart failure, to improve survival in certain individuals following myocardial infarction, and to prevent progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00015ReteplaseHuman tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF).
DrugDrug NamePhaseStatusCount
DB00683Midazolam1Completed1
DB00058Alpha-1-proteinase inhibitor1 / 2Completed1
DB00099Filgrastim1 / 2Completed1
DB00054Abciximab2Active Not Recruiting1
DB00026Anakinra2Completed1
DB11723Dutogliptin2Recruiting1
DB00063Eptifibatide2Unknown Status1
DB00016Erythropoietin2Unknown Status1
DB00099Filgrastim2Completed1
DB00099Filgrastim2Recruiting1
DB05549INO-10012Completed1
DB01065Melatonin2Completed1
DB01065Melatonin2Terminated1
DB09107Methoxy polyethylene glycol-epoetin beta2Completed1
DB04899Nesiritide2Completed1
DB00435Nitric Oxide2Completed1
DB00435Nitric Oxide2Terminated1
DB09112Nitrous acid2Completed1
DB09140Oxygen2Completed1
DB11194Pyruvic acid2Completed1
DB01098Rosuvastatin2Unknown Status1
DB01236Sevoflurane2Completed1
DB00641Simvastatin2Unknown Status1
DB00031Tenecteplase2Completed1
DB12003Thymosin beta-42Suspended1
DB00945Acetylsalicylic acid2 / 3Recruiting1
DB00026Anakinra2 / 3Active Not Recruiting1
DB00254Doxycycline2 / 3Active Not Recruiting1
DB11242Gelatin2 / 3Unknown Status1
DB01261Sitagliptin2 / 3Unknown Status1
DB09153Sodium Chloride2 / 3Unknown Status1
DB00054Abciximab3Terminated1
DB00640Adenosine3Completed1
DB06605Apixaban3Not Yet Recruiting1
DB00006Bivalirudin3Active Not Recruiting1
DB00006Bivalirudin3Recruiting1
DB00758Clopidogrel3Completed1
DB09038Empagliflozin3Recruiting1
DB01225Enoxaparin3Completed1
DB01109Heparin3Completed1
DB01109Heparin3Recruiting1
DB00028Immune Globulin Human3Completed1
DB09140Oxygen3Completed1
DB04949Pexelizumab3Completed1
DB00178Ramipril3Recruiting1
DB09292Sacubitril3Recruiting1
DB09153Sodium Chloride3Completed1
DB00086Streptokinase3Completed1
DB08816Ticagrelor3Completed1
DB00775Tirofiban3Completed1
DB00177Valsartan3Recruiting1
DB00682Warfarin3Not Yet Recruiting1
DB00054Abciximab4Completed2
DB06151Acetylcysteine4Completed1
DB01076Atorvastatin4Completed2
DB01393Bezafibrate4Completed1
DB00612Bisoprolol4Recruiting1
DB00006Bivalirudin4Completed1
DB06441Cangrelor4Recruiting1
DB00758Clopidogrel4Completed3
DB00758Clopidogrel4Withdrawn1
DB01394Colchicine4Recruiting1
DB01394Colchicine4Unknown Status1
DB00343Diltiazem4Completed1
DB00016Erythropoietin4Unknown Status1
DB01109Heparin4Completed1
DB00047Insulin Glargine4Completed1
DB00046Insulin Lispro4Completed1
DB01249Iodixanol4Completed1
DB09156Iopromide4Completed1
DB01233Metoclopramide4Recruiting1
DB00264Metoprolol4Completed1
DB00264Metoprolol4Recruiting1
DB00727Nitroglycerin4Completed1
DB06209Prasugrel4Recruiting1
DB00175Pravastatin4Unknown Status1
DB00086Streptokinase4Completed2
DB00031Tenecteplase4Terminated1
DB08816Ticagrelor4Recruiting3
DB00775Tirofiban4Completed3
DB00775Tirofiban4Unknown Status1
DB00661Verapamil4Completed1
DB00316AcetaminophenNot AvailableWithdrawn1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB00796Candesartan cilexetilNot AvailableTerminated1
DB01136CarvedilolNot AvailableCompleted1
DB11121ChloroxylenolNot AvailableCompleted1
DB11121ChloroxylenolNot AvailableUnknown Status1
DB00758ClopidogrelNot AvailableRecruiting1
DB00115CyanocobalaminNot AvailableCompleted1
DB12362Diaminohydroxypropanetetraacetic acidNot AvailableRecruiting1
DB01225EnoxaparinNot AvailableCompleted1
DB00813FentanylNot AvailableCompleted1
DB00158Folic AcidNot AvailableCompleted1
DB06655LiraglutideNot AvailableRecruiting1
DB00295MorphineNot AvailableCompleted1
DB09220NicorandilNot AvailableCompleted2
DB00165PyridoxineNot AvailableCompleted1
DB00966TelmisartanNot AvailableTerminated1
DB08816TicagrelorNot AvailableCompleted1
DB08816TicagrelorNot AvailableRecruiting1