Stroke, Ischemic

Also known as: Ischemic Stroke / Ischemic Strokes / Ischaemic stroke NOS / Ischaemic stroke

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
DB00975DipyridamoleA phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
DB00622NicardipineA potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidNuclear factor kappa b beta subunittarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00975DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB00975DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00975DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00975DipyridamoleAdenosine deaminasetarget
DB00975DipyridamoleMultidrug resistance-associated protein 4transporter
DB00975DipyridamoleMultidrug resistance-associated protein 5transporter
DB00975DipyridamoleMultidrug resistance protein 1transporter
DB00975DipyridamoleCalcipressin-1target
DB00975DipyridamoleAlpha-1-acid glycoprotein 1target
DB00975DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DB00975DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DB00975DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DB00975DipyridamoleBile salt export pumptransporter
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineMultidrug resistance protein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DrugDrug NamePhaseStatusCount
DB00945Acetylsalicylic acid0Recruiting1
DB01076Atorvastatin0Unknown Status1
DB00758Clopidogrel0Recruiting1
DB01043Memantine0Recruiting1
DB11127Selenious acid0Not Yet Recruiting1
DB11135Selenium0Not Yet Recruiting1
DB00945Acetylsalicylic acid1Withdrawn1
DB00009Alteplase1Withdrawn1
DB14942BMS-9861411Completed1
DB12153Citicoline1Withdrawn1
DB09341Dextrose, unspecified form1Recruiting1
DB00099Filgrastim1Unknown Status1
DB00028Immune Globulin Human1Withdrawn1
DB00653Magnesium sulfate1Recruiting1
DB01345Potassium cation1Recruiting1
DB00015Reteplase1Withdrawn1
DB11670SP-82031Unknown Status1
DB00203Sildenafil1Terminated1
DB00661Verapamil1Completed1
DB00661Verapamil1Recruiting2
DB00661Verapamil1Withdrawn1
DB00682Warfarin1Withdrawn1
DB00316Acetaminophen1 / 2Recruiting1
DB00278Argatroban1 / 2Completed1
DB01200Bromocriptine1 / 2Recruiting1
DB06774Capsaicin1 / 2Completed1
DB11121Chloroxylenol1 / 2Active Not Recruiting1
DB11121Chloroxylenol1 / 2Recruiting1
DB00016Erythropoietin1 / 2Completed1
DB01016Glyburide1 / 2Completed1
DB05914Mesenchymal Stem Cells1 / 2Withdrawn1
DB00945Acetylsalicylic acid2Completed1
DB00009Alteplase2Active Not Recruiting1
DB00009Alteplase2Completed2
DB00278Argatroban2Terminated1
DB12123Cinepazide2Unknown Status1
DB00215Citalopram2Completed1
DB01003Cromoglicic acid2Suspended1
DB06618Cutamesine2Completed1
DB00843Donepezil2Completed1
DB00063Eptifibatide2Completed2
DB00016Erythropoietin2Not Yet Recruiting1
DB01276Exenatide2Recruiting1
DB00099Filgrastim2Completed1
DB00472Fluoxetine2Completed1
DB00472Fluoxetine2Not Yet Recruiting1
DB01016Glyburide2Active Not Recruiting1
DB04861Nebivolol2Recruiting1
DB00627Niacin2Completed1
DB00727Nitroglycerin2Recruiting1
DB00275Olmesartan2Recruiting1
DB00015Reteplase2Active Not Recruiting1
DB00015Reteplase2Recruiting1
DB06228Rivaroxaban2Completed1
DB11670SP-82032Active Not Recruiting1
DB09153Sodium chloride2Recruiting1
DB00086Streptokinase2Unknown Status1
DB00031Tenecteplase2Active Not Recruiting1
DB00031Tenecteplase2Completed1
DB00031Tenecteplase2Recruiting1
DB06822Tinzaparin2Completed1
DB00682Warfarin2Completed2
DB00945Acetylsalicylic acid2 / 3Not Yet Recruiting1
DB00945Acetylsalicylic acid2 / 3Terminated1
DB00945Acetylsalicylic acid2 / 3Unknown Status2
DB00009Alteplase2 / 3Recruiting1
DB00009Alteplase2 / 3Withdrawn1
DB06605Apixaban2 / 3Unknown Status1
DB00758Clopidogrel2 / 3Terminated1
DB00758Clopidogrel2 / 3Unknown Status1
DB15127Hydrogen2 / 3Recruiting1
DB00125L-Arginine2 / 3Terminated1
DB01017Minocycline2 / 3Recruiting1
DB06228Rivaroxaban2 / 3Unknown Status1
DB00031Tenecteplase2 / 3Withdrawn1
DB00775Tirofiban2 / 3Recruiting1
DB00945Acetylsalicylic acid3Completed2
DB00945Acetylsalicylic acid3Recruiting1
DB00009Alteplase3Completed1
DB00009Alteplase3Not Yet Recruiting1
DB00009Alteplase3Recruiting1
DB00758Clopidogrel3Completed1
DB00758Clopidogrel3Recruiting1
DB00843Donepezil3Unknown Status1
DB01249Iodixanol3Completed1
DB08918Levomilnacipran3Completed1
DB06655Liraglutide3Not Yet Recruiting1
DB01043Memantine3Not Yet Recruiting1
DB00175Pravastatin3Completed1
DB00641Simvastatin3Completed1
DB09153Sodium chloride3Terminated1
DB11104Sulfur hexafluoride3Completed1
DB11104Sulfur hexafluoride3Terminated1
DB00031Tenecteplase3Completed1
DB00031Tenecteplase3Not Yet Recruiting2
DB00031Tenecteplase3Recruiting1
DB08816Ticagrelor3Recruiting1
DB03424Ubenimex3Completed1
DB00945Acetylsalicylic acid4Completed1
DB00945Acetylsalicylic acid4Not Yet Recruiting1
DB00381Amlodipine4Completed1
DB00335Atenolol4Active Not Recruiting1
DB01076Atorvastatin4Completed2
DB01076Atorvastatin4Recruiting1
DB01166Cilostazol4Completed1
DB01166Cilostazol4Recruiting1
DB00758Clopidogrel4Completed1
DB00758Clopidogrel4Recruiting1
DB09279Fimasartan4Active Not Recruiting1
DB12545Indobufen4Not Yet Recruiting1
DB00678Losartan4Completed1
DB01599Probucol4Recruiting1
DB01098Rosuvastatin4Completed1
DB09153Sodium chloride4Completed1
DB00177Valsartan4Active Not Recruiting1
DB00682Warfarin4Completed1
DB00945Acetylsalicylic acidNot AvailableRecruiting2
DB00945Acetylsalicylic acidNot AvailableUnknown Status1
DB00009AlteplaseNot AvailableRecruiting2
DB00009AlteplaseNot AvailableTerminated1
DB00009AlteplaseNot AvailableUnknown Status1
DB06605ApixabanNot AvailableCompleted3
DB06605ApixabanNot AvailableNot Yet Recruiting1
DB00758ClopidogrelNot AvailableRecruiting2
DB06695Dabigatran etexilateNot AvailableCompleted2
DB12362Diaminopropanol tetraacetic acidNot AvailableRecruiting2
DB09374Indocyanine green acid formNot AvailableActive Not Recruiting1
DB04896MilnacipranNot AvailableUnknown Status1
DB00899RemifentanilNot AvailableCompleted1
DB06228RivaroxabanNot AvailableCompleted3
DB00013UrokinaseNot AvailableRecruiting1
DB00285VenlafaxineNot AvailableRecruiting1
DB00682WarfarinNot AvailableCompleted2