Post Traumatic Stress Disorder (PTSD)

Also known as: Stress Disorder, Post Traumatic / Post Traumatic Stress Disorders / Post Traumatic Stress Disorder, PTSD / Post Traumatic Stress Disorder PTSD / Post Traumatic Stress Disorder / Post-Traumatic Stress Disorders / Stress Disorders, Post-Traumatic / Stress Disorder, Post-Traumatic / Post-Traumatic Stress Disorder (PTSD) / Posttraumatic Stress Disorder (PTSD) / Post-Traumatic Stress Disorder / PTSD, Post Traumatic Stress Disorder / PTSD / Stress Disorders, Post Traumatic / PTSD - Post Traumatic Stress Disorder / Traumatic neurosis / Post-traumatic stress disorder, unspecified

DrugDrug NameDrug Description
DB00215CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
DB00458ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
DB00334OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
DB00715ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
DB00457PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
DB01224QuetiapineA psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.
DB01104SertralineA selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
DrugDrug NameTargetType
DB00215CitalopramSodium-dependent serotonin transportertarget
DB00215CitalopramCytochrome P450 2C19enzyme
DB00215CitalopramCytochrome P450 2D6enzyme
DB00215CitalopramCytochrome P450 3A4enzyme
DB00215CitalopramP-glycoprotein 1transporter
DB00215CitalopramCytochrome P450 1A2enzyme
DB00215CitalopramHistamine H1 receptortarget
DB00458ImipramineSodium-dependent noradrenaline transportertarget
DB00458ImipramineSodium-dependent serotonin transportertarget
DB00458ImipramineCytochrome P450 1A2enzyme
DB00458ImipramineCytochrome P450 2C19enzyme
DB00458ImipramineCytochrome P450 2D6enzyme
DB00458ImipramineHistamine H1 receptortarget
DB00458ImipramineAlpha-1A adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 2Atarget
DB00458ImipramineMuscarinic acetylcholine receptor M1target
DB00458ImipramineMuscarinic acetylcholine receptor M2target
DB00458ImipramineMuscarinic acetylcholine receptor M3target
DB00458ImipramineMuscarinic acetylcholine receptor M4target
DB00458ImipramineMuscarinic acetylcholine receptor M5target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 2target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 3target
DB00458ImipramineAlpha-1D adrenergic receptortarget
DB00458ImipramineAlpha-1-acid glycoprotein 1carrier
DB00458ImipramineSolute carrier family 22 member 2transporter
DB00458ImipramineSolute carrier family 22 member 3transporter
DB00458ImipramineP-glycoprotein 1transporter
DB00458ImipramineSolute carrier family 22 member 4transporter
DB00458ImipramineCytochrome P450 3A4enzyme
DB00458ImipramineCytochrome P450 2B6enzyme
DB00458ImipramineCytochrome P450 2C18enzyme
DB00458ImipramineCytochrome P450 2E1enzyme
DB00458ImipramineCytochrome P450 3A7enzyme
DB00458Imipramine5-hydroxytryptamine receptor 2Ctarget
DB00458ImipramineAlpha-1B adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 7target
DB00458ImipramineD(1) dopamine receptortarget
DB00458ImipramineDopamine D2 receptortarget
DB00458ImipraminePotassium voltage-gated channel subfamily H member 2target
DB00458ImipramineSodium-dependent dopamine transportertarget
DB00458Imipramine5-hydroxytryptamine receptor 1Atarget
DB00458Imipramine5-hydroxytryptamine receptor 6target
DB00458ImipraminePotassium voltage-gated channel subfamily H member 1target
DB00458ImipramineSerum albumincarrier
DB00458ImipramineAlpha-1-acid glycoprotein 2target
DB00334OlanzapineDopamine D1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineDopamine D4 receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineDopamine D2 receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineDopamine D3 receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineDopamine D5 receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineP-glycoprotein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineBeta adrenergic receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 1target
DB00334OlanzapineGABA-A receptor (benzodiazepine site)target
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineUDP-glucuronosyltransferase 1-4enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334OlanzapineCytochrome P450 3A Subfamilyenzyme
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineP-glycoprotein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00715ParoxetineAlpha-1 adrenergic receptorstarget
DB00715ParoxetineAlpha-2 adrenergic receptorstarget
DB00715ParoxetineBeta adrenergic receptortarget
DB00715ParoxetineDopamine D2 receptortarget
DB00715ParoxetineHistamine H1 receptortarget
DB00715ParoxetineSerotonin Receptorstarget
DB00715ParoxetineMuscarinic acetylcholine receptortarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Btarget
DB00715ParoxetineD(1) dopamine receptortarget
DB00715ParoxetineCytochrome P450 2C19enzyme
DB00457PrazosinAlpha-1A adrenergic receptortarget
DB00457PrazosinAlpha-1B adrenergic receptortarget
DB00457PrazosinAlpha-1D adrenergic receptortarget
DB00457PrazosinPotassium voltage-gated channel subfamily H member 2target
DB00457PrazosinAlpha-1-acid glycoprotein 1carrier
DB00457PrazosinSolute carrier family 22 member 1transporter
DB00457PrazosinSolute carrier family 22 member 3transporter
DB00457PrazosinP-glycoprotein 1transporter
DB00457PrazosinATP-binding cassette sub-family G member 2transporter
DB00457PrazosinAlpha-2A adrenergic receptortarget
DB00457PrazosinAlpha-2B adrenergic receptortarget
DB00457PrazosinAlpha-1 adrenergic receptorstarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Ctarget
DB01224QuetiapineDopamine D2 receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Atarget
DB01224QuetiapineHistamine H1 receptortarget
DB01224QuetiapineCytochrome P450 3A4enzyme
DB01224QuetiapineAlpha-1 adrenergic receptorstarget
DB01224QuetiapineAlpha-2A adrenergic receptortarget
DB01224QuetiapineAlpha-2B adrenergic receptortarget
DB01224QuetiapineAlpha-2C adrenergic receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Dtarget
DB01224QuetiapineMuscarinic acetylcholine receptor M1target
DB01224QuetiapineMuscarinic acetylcholine receptor M2target
DB01224QuetiapineMuscarinic acetylcholine receptor M3target
DB01224QuetiapineMuscarinic acetylcholine receptor M4target
DB01224QuetiapineMuscarinic acetylcholine receptor M5target
DB01224Quetiapine5-hydroxytryptamine receptor 1Btarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Etarget
DB01224Quetiapine5-hydroxytryptamine receptor 3Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 6target
DB01224Quetiapine5-hydroxytryptamine receptor 7target
DB01224QuetiapineDopamine D5 receptortarget
DB01224QuetiapineDopamine D1 receptortarget
DB01224QuetiapineDopamine D3 receptortarget
DB01224QuetiapineDopamine D4 receptortarget
DB01224QuetiapineCytochrome P450 3A5enzyme
DB01224QuetiapineP-glycoprotein 1transporter
DB01224QuetiapineCytochrome P450 2C19enzyme
DB01224QuetiapineCytochrome P450 2D6enzyme
DB01224QuetiapineCytochrome P450 3A7enzyme
DB01104SertralineSodium-dependent serotonin transportertarget
DB01104SertralineCytochrome P450 2B6enzyme
DB01104SertralineCytochrome P450 2C19enzyme
DB01104SertralineCytochrome P450 2C9enzyme
DB01104SertralineCytochrome P450 2D6enzyme
DB01104SertralineSodium-dependent dopamine transportertarget
DB01104SertralineCYP2B proteinenzyme
DB01104SertralineCytochrome P450 3A4enzyme
DB01104SertralineAmine oxidase [flavin-containing] Benzyme
DB01104SertralineAmine oxidase [flavin-containing] Aenzyme
DB01104SertralineP-glycoprotein 1transporter
DB01104SertralineSerum albumincarrier
DB01104SertralineSigma receptortarget
DrugDrug NamePhaseStatusCount
DB00783Estradiol0Not Yet Recruiting1
DB00422Methylphenidate0Completed1
DB00107Oxytocin0Completed1
DB00590Doxazosin1Recruiting1
DB01018Guanfacine1Completed1
DB01221Ketamine1Completed1
DB01221Ketamine1Recruiting1
DB05096LY21400231Terminated1
DB11889Lanicemine1Recruiting1
DB01454Midomafetamine1Recruiting1
DB00834Mifepristone1Completed1
DB00627Niacin1Recruiting1
DB00790Perindopril1Recruiting1
DB00740Riluzole1Active Not Recruiting1
DB09061Cannabidiol1 / 2Not Yet Recruiting1
DB00590Doxazosin1 / 2Active Not Recruiting1
DB01221Ketamine1 / 2Recruiting1
DB14009Medical Cannabis1 / 2Terminated1
DB00486Nabilone1 / 2Terminated1
DB11788Neuropeptide Y1 / 2Not Yet Recruiting1
DB00715Paroxetine1 / 2Completed1
DB00571Propranolol1 / 2Terminated1
DB00740Riluzole1 / 2Unknown Status1
DB00734Risperidone1 / 2Completed1
DB01104Sertraline1 / 2Completed1
DB06151Acetylcysteine2Active Not Recruiting1
DB06151Acetylcysteine2Completed1
DB06151Acetylcysteine2Recruiting1
DB01238Aripiprazole2Completed1
DB00335Atenolol2Recruiting1
DB01076Atorvastatin2Terminated1
DB09128Brexpiprazole2Completed1
DB09128Brexpiprazole2Terminated1
DB00921Buprenorphine2Not Yet Recruiting1
DB00921Buprenorphine2Recruiting1
DB09061Cannabidiol2Recruiting1
DB01136Carvedilol2Unknown Status1
DB00924Cyclobenzaprine2Completed2
DB00260Cycloserine2Unknown Status2
DB00590Doxazosin2Active Not Recruiting1
DB00590Doxazosin2Recruiting1
DB05087Ganaxolone2Completed1
DB04946Iloperidone2Completed1
DB01221Ketamine2Completed1
DB01221Ketamine2Recruiting1
DB00678Losartan2Recruiting1
DB14009Medical Cannabis2Recruiting1
DB00683Midazolam2Completed1
DB01454Midomafetamine2Active Not Recruiting1
DB01454Midomafetamine2Completed1
DB01454Midomafetamine2Not Yet Recruiting1
DB00834Mifepristone2Completed1
DB00834Mifepristone2Recruiting1
DB00704Naltrexone2Not Yet Recruiting1
DB00704Naltrexone2Recruiting1
DB12979Nepicastat2Withdrawn1
DB00325Nitroprusside2Recruiting1
DB06690Nitrous oxide2Recruiting1
DB12427Orvepitant2Completed1
DB00107Oxytocin2Active Not Recruiting1
DB00107Oxytocin2Completed2
DB12012PF-044578452Terminated1
DB00715Paroxetine2Terminated1
DB00388Phenylephrine2Recruiting1
DB01708Prasterone2Completed1
DB00457Prazosin2Recruiting1
DB02789Pregnenolone2Withdrawn1
DB00571Propranolol2Completed2
DB00571Propranolol2Recruiting2
DB01104Sertraline2Completed3
DB01104Sertraline2Terminated1
DB09072Sodium oxybate2Withdrawn1
DB00273Topiramate2Not Yet Recruiting1
DB01273Varenicline2Completed1
DB12512Verucerfont2Completed2
DB12436Vofopitant2Completed1
DB01392Yohimbine2Completed1
DB00246Ziprasidone2Terminated1
DB00909Zonisamide2Completed1
DB00909Zonisamide2Recruiting1
DB00404Alprazolam2 / 3Completed1
DB01156Bupropion2 / 3Completed1
DB00260Cycloserine2 / 3Completed1
DB00260Cycloserine2 / 3Recruiting1
DB00260Cycloserine2 / 3Unknown Status1
DB01221Ketamine2 / 3Recruiting1
DB01221Ketamine2 / 3Withdrawn1
DB01202Levetiracetam2 / 3Completed1
DB00683Midazolam2 / 3Recruiting1
DB00683Midazolam2 / 3Withdrawn1
DB00184Nicotine2 / 3Completed1
DB00715Paroxetine2 / 3Completed1
DB00396Progesterone2 / 3Recruiting1
DB00571Propranolol2 / 3Unknown Status1
DB00734Risperidone2 / 3Completed1
DB01104Sertraline2 / 3Completed1
DB13453Xenon2 / 3Not Yet Recruiting1
DB09128Brexpiprazole3Recruiting1
DB09128Brexpiprazole3Terminated1
DB00924Cyclobenzaprine3Completed1
DB00924Cyclobenzaprine3Recruiting1
DB00924Cyclobenzaprine3Terminated2
DB00260Cycloserine3Completed1
DB01151Desipramine3Completed1
DB00472Fluoxetine3Completed1
DB00555Lamotrigine3Withdrawn1
DB00704Naltrexone3Completed1
DB00715Paroxetine3Completed3
DB00413Pramipexole3Recruiting1
DB00457Prazosin3Completed2
DB00230Pregabalin3Recruiting1
DB00571Propranolol3Recruiting1
DB01224Quetiapine3Completed1
DB01104Sertraline3Completed2
DB01104Sertraline3Recruiting1
DB01104Sertraline3Terminated1
DB00273Topiramate3Withdrawn1
DB00313Valproic acid3Completed1
DB00289Atomoxetine4Completed1
DB01156Bupropion4Not Yet Recruiting1
DB01068Clonazepam4Completed1
DB00260Cycloserine4Completed1
DB01234Dexamethasone4Completed1
DB00590Doxazosin4Completed1
DB01175Escitalopram4Completed1
DB00783Estradiol4Recruiting1
DB00402Eszopiclone4Completed1
DB00502Haloperidol4Completed1
DB00741Hydrocortisone4Withdrawn1
DB01235Levodopa4Completed1
DB01043Memantine4Completed1
DB06148Mianserin4Completed1
DB00834Mifepristone4Completed1
DB01017Minocycline4Recruiting1
DB00370Mirtazapine4Completed2
DB00704Naltrexone4Completed1
DB00107Oxytocin4Active Not Recruiting1
DB00107Oxytocin4Completed1
DB00107Oxytocin4Not Yet Recruiting1
DB00715Paroxetine4Completed7
DB00715Paroxetine4Terminated1
DB00457Prazosin4Completed2
DB00571Propranolol4Completed1
DB00571Propranolol4Terminated1
DB00571Propranolol4Unknown Status1
DB01224Quetiapine4Completed3
DB00734Risperidone4Completed1
DB01104Sertraline4Completed7
DB01104Sertraline4Terminated1
DB00273Topiramate4Completed3
DB00273Topiramate4Recruiting1
DB00193Tramadol4Unknown Status1
DB00313Valproic acid4Terminated1
DB00285Venlafaxine4Completed1
DB06684Vilazodone4Completed1
DB09068Vortioxetine4Recruiting1
DB00246Ziprasidone4Completed1
DB00921BuprenorphineNot AvailableCompleted1
DB01156BupropionNot AvailableCompleted1
DB00260CycloserineNot AvailableCompleted1
DB01234DexamethasoneNot AvailableCompleted1
DB00841DobutamineNot AvailableCompleted1
DB00470DronabinolNot AvailableRecruiting1
DB00476DuloxetineNot AvailableActive Not Recruiting1
DB01175EscitalopramNot AvailableCompleted3
DB00472FluoxetineNot AvailableActive Not Recruiting1
DB00741HydrocortisoneNot AvailableCompleted2
DB00741HydrocortisoneNot AvailableRecruiting1
DB00741HydrocortisoneNot AvailableUnknown Status1
DB00741HydrocortisoneNot AvailableWithdrawn1
DB14541Hydrocortisone cypionateNot AvailableWithdrawn1
DB01221KetamineNot AvailableCompleted3
DB01221KetamineNot AvailableRecruiting3
DB00186LorazepamNot AvailableUnknown Status1
DB00333MethadoneNot AvailableCompleted1
DB00834MifepristoneNot AvailableCompleted1
DB01183NaloxoneNot AvailableCompleted1
DB00184NicotineNot AvailableCompleted1
DB00184NicotineNot AvailableRecruiting1
DB00107OxytocinNot AvailableUnknown Status1
DB05596PRX-03140Not AvailableCompleted1
DB00715ParoxetineNot AvailableActive Not Recruiting1
DB00715ParoxetineNot AvailableCompleted1
DB00715ParoxetineNot AvailableTerminated1
DB00715ParoxetineNot AvailableWithdrawn1
DB00388PhenylephrineNot AvailableCompleted1
DB00457PrazosinNot AvailableCompleted3
DB00457PrazosinNot AvailableTerminated3
DB00457PrazosinNot AvailableUnknown Status2
DB00635PrednisoneNot AvailableCompleted1
DB00571PropranololNot AvailableRecruiting1
DB01224QuetiapineNot AvailableCompleted2
DB00273TopiramateNot AvailableTerminated1
DB00285VenlafaxineNot AvailableActive Not Recruiting1