Pain, Neuropathic

Also known as: Neuropathic Pains / Neuropathic Pain / Neuralgia / Neuralgia NOS

DrugDrug NameDrug Description
DB00286Conjugated estrogensConjugated estrogens, or Conjugated Equine Estrogens (CEEs) are composed of a mixture of the water-soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids that are purified from pregnant horse urine. Available as the product Premarin (FDA), this combination of equine-derived estrogenic compounds is indicated for the following conditions: treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy associated with menopause; hypoestrogenism due to hypogonadism, castration or primary ovarian failure; palliation of metastatic breast cancer; palliation of advanced androgen-dependent carcinoma of the prostate; and for prevention of postmenopausal osteoporosis. All estrogen products mimic the effects of endogenous estrogens in the body which are responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. Estrogens act by binding to estrogen receptors on a wide variety of tissues in the body and modulating the pituitary secretion of the gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH) through a negative feedback mechanism. Prior to menopause, the primary source of estrogen is the ovarian follicle, which secretes 70-500 micrograms of estradiol daily, depending on the phase of the menstrual cycle. However, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control. This shift in hormone production is largely responsible for many of the symptoms experienced during and after menopause and includes hot flashes and other vasomotor symptoms, painful intercourse, vaginal dryness, and vulvovaginal atrophy. These symptoms are able to be reduced by replacing many of the hormones lost during and following menopause with synthetic or naturally occurring forms, in a therapy known as Hormone Replacement Therapy (HRT). Pharmacologic estrogen products are available in a variety of formats. Although many of them contain several compounds in common (such as the estrogen derivatives sodium estrone sulfate and sodium equilin sulfate), they vary by their original source (such as horse-, human-, or plant-derived), and the remaining mixture of estrogenic derivatives. Conjugated Equine Estrogens (CEEs) are derived from the urine of pregnant mares and contain a blend of at least 10 estrogen derivatives. Marketed under the brand name Premarin, CEEs are the most frequently used form of conjugated estrogens. There is currently no generic form of CEEs available as a detailed analytical characterization of the active ingredients or of their estrogenic activity is not available at this time. Conjugated estrogens are also available in a plant-derived synthetic form that replicates the naturally occurring, horse-derived forms. Available as either "Synthetic Conjugated Estrogens, A" containing 9 estrogen derivatives (available as Cenestin) or as "Synthetic Conjugated Estrogens, B" containing 10 estrogen derivatives (available as Enjuvia), these products are isolated as precursors from yam or soy plants and then chemically modified to mimic the products available in their naturally occurring form.
DB01151DesipramineDesipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Secondary amine TCAs, such as desipramine and nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline and doxepine. TCAs also down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Desipramine exerts less anticholinergic and sedative side effects compared to tertiary amine TCAs, such as amitriptyline and clomipramine. Desipramine may be used to treat depression, neuropathic pain (unlabeled use), agitation and insomnia (unlabeled use) and attention-deficit hyperactivity disorder (unlabeled use).
DB01142DoxepinDoxepin is a dibenzoxepin-derivative tricyclic antidepressant (TCA). Structurally similar to phenothiazines, TCAs contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, doxepin does not affect mood or arousal, but may cause sedation. In depressed individuals, doxepin exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Tertiary amine TCAs, such as doxepin and amitriptyline, are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and desipramine. TCAs also down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. Doxepin has less sedative and anticholinergic effects than amitriptyline. See toxicity section below for a complete listing of side effects. When orally administered, doxepin may be used to treat depression and insomnia. Unlabeled indications of oral doxepin also include chronic and neuropathic pain, and anxiety. Doxepin may also be used as a second line agent to treat idiopathic urticaria. As a topical agent, doxepin may be used relieve itching in patients with certain types of eczema. It may be used for the management of moderate pruritus in adult patients with atopic dermatitis or lichen simplex chronicus.
DB00327HydromorphoneAn opioid analgesic derived from morphine and used mainly as an analgesic. It has a shorter duration of action and is more potent than morphine.
DB00458ImipramineImipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Tertiary amine TCAs, such as imipramine and amitriptyline, are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and desipramine. TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively [A6584]. Imipramine has less sedative and anticholinergic effects than the tertiary amine TCAs, amitriptyline and clomipramine. Imipramine may be used to treat depression and nocturnal enuresis in children [FDA Label]. Unlabeled indications include chronic and neuropathic pain (including diabetic neuropathy), panic disorder, attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder (PTSD) [L1349,L1348,A31900,L1351,L1352,L1353,A31904].
DB00230PregabalinPregabalin is an anticonvulsant drug used for neuropathic pain, epilepsy and generalized anxiety disorder.[A31161] Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin achieves antihyperalgesic activity by binding to the α2δ subunit of the voltage-dependent calcium channels [A31162]. Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended release).[L1006] It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders [A31161].
DB00285VenlafaxineVenlafaxine (Effexor) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class first introduced by Wyeth in 1993. It is prescribed for the treatment of clinical depression and anxiety disorders. Due to the pronounced side effects and suspicions that venlafaxine may significantly increase the risk of suicide it is not recommended as a first line treatment of depression. However, it is often effective for depression not responding to SSRIs. Venlafaxine was the sixth most widely-used antidepressant based on the amount of retail prescriptions in the US (17.1 million) in 2006.
DrugDrug NameTargetType
DB00286Conjugated estrogensEstrogen receptor alphatarget
DB00286Conjugated estrogensCytochrome P450 3A4enzyme
DB00286Conjugated estrogensCytochrome P450 1A2enzyme
DB00286Conjugated estrogensCatechol O-methyltransferaseenzyme
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 4transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
DB00286Conjugated estrogensSodium/bile acid cotransportertransporter
DB00286Conjugated estrogensSolute carrier family 22 member 10transporter
DB00286Conjugated estrogensSolute carrier family 22 member 8transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
DB00286Conjugated estrogensMultidrug resistance protein 1transporter
DB00286Conjugated estrogensSolute carrier family 22 member 6transporter
DB00286Conjugated estrogensOrganic solute transporter subunit alphatransporter
DB00286Conjugated estrogensOrganic solute transporter subunit betatransporter
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family C member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
DB00286Conjugated estrogensSolute carrier family 22 member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family G member 2transporter
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineMultidrug resistance protein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2A6enzyme
DB01151DesipramineCytochrome P450 2C18enzyme
DB01151DesipramineCytochrome P450 2C19enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineD(2) dopamine receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB01142DoxepinSodium-dependent serotonin transportertarget
DB01142DoxepinSodium-dependent noradrenaline transportertarget
DB01142DoxepinHistamine H1 receptortarget
DB01142DoxepinHistamine H2 receptortarget
DB01142DoxepinCytochrome P450 2D6enzyme
DB01142DoxepinMuscarinic acetylcholine receptor M1target
DB01142DoxepinMuscarinic acetylcholine receptor M2target
DB01142DoxepinMuscarinic acetylcholine receptor M3target
DB01142DoxepinMuscarinic acetylcholine receptor M4target
DB01142DoxepinMuscarinic acetylcholine receptor M5target
DB01142DoxepinAlpha-1A adrenergic receptortarget
DB01142Doxepin5-hydroxytryptamine receptor 1Atarget
DB01142Doxepin5-hydroxytryptamine receptor 2Atarget
DB01142DoxepinD(2) dopamine receptortarget
DB01142DoxepinCytochrome P450 2C19enzyme
DB01142DoxepinCytochrome P450 2C9enzyme
DB01142DoxepinCytochrome P450 1A2enzyme
DB01142DoxepinAlpha-1-acid glycoprotein 1carrier
DB01142DoxepinMultidrug resistance protein 1transporter
DB01142Doxepin5-hydroxytryptamine receptor 2Btarget
DB01142Doxepin5-hydroxytryptamine receptor 2Ctarget
DB01142DoxepinAlpha-1B adrenergic receptortarget
DB01142DoxepinAlpha-1D adrenergic receptortarget
DB01142DoxepinAlpha-2A adrenergic receptortarget
DB01142DoxepinAlpha-2B adrenergic receptortarget
DB01142DoxepinAlpha-2C adrenergic receptortarget
DB01142DoxepinCytochrome P450 3A4enzyme
DB01142Doxepin5-hydroxytryptamine receptor 6target
DB01142DoxepinHistamine H4 receptortarget
DB01142DoxepinPotassium voltage-gated channel subfamily H member 2target
DB00327HydromorphoneMu-type opioid receptortarget
DB00327HydromorphoneDelta-type opioid receptortarget
DB00327HydromorphoneKappa-type opioid receptortarget
DB00327HydromorphoneCytochrome P450 3A4enzyme
DB00327HydromorphoneCytochrome P450 2C9enzyme
DB00327HydromorphoneProstaglandin G/H synthase 1enzyme
DB00327HydromorphoneUDP-glucuronosyltransferase 1-9enzyme
DB00458ImipramineSodium-dependent noradrenaline transportertarget
DB00458ImipramineSodium-dependent serotonin transportertarget
DB00458ImipramineCytochrome P450 1A2enzyme
DB00458ImipramineCytochrome P450 2C19enzyme
DB00458ImipramineCytochrome P450 2D6enzyme
DB00458ImipramineHistamine H1 receptortarget
DB00458ImipramineAlpha-1A adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 2Atarget
DB00458ImipramineMuscarinic acetylcholine receptor M1target
DB00458ImipramineMuscarinic acetylcholine receptor M2target
DB00458ImipramineMuscarinic acetylcholine receptor M3target
DB00458ImipramineMuscarinic acetylcholine receptor M4target
DB00458ImipramineMuscarinic acetylcholine receptor M5target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 2target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 3target
DB00458ImipramineAlpha-1D adrenergic receptortarget
DB00458ImipramineAlpha-1-acid glycoprotein 1carrier
DB00458ImipramineSolute carrier family 22 member 2transporter
DB00458ImipramineSolute carrier family 22 member 3transporter
DB00458ImipramineMultidrug resistance protein 1transporter
DB00458ImipramineSolute carrier family 22 member 4transporter
DB00458ImipramineCytochrome P450 3A4enzyme
DB00458ImipramineCytochrome P450 2B6enzyme
DB00458ImipramineCytochrome P450 2C18enzyme
DB00458ImipramineCytochrome P450 2E1enzyme
DB00458ImipramineCytochrome P450 3A7enzyme
DB00458Imipramine5-hydroxytryptamine receptor 2Ctarget
DB00458ImipramineAlpha-1B adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 7target
DB00458ImipramineD(1) dopamine receptortarget
DB00458ImipramineD(2) dopamine receptortarget
DB00458ImipraminePotassium voltage-gated channel subfamily H member 2target
DB00458ImipramineSodium-dependent dopamine transportertarget
DB00458Imipramine5-hydroxytryptamine receptor 1Atarget
DB00458Imipramine5-hydroxytryptamine receptor 6target
DB00458ImipraminePotassium voltage-gated channel subfamily H member 1target
DB00458ImipramineSerum albumincarrier
DB00458ImipramineAlpha-1-acid glycoprotein 2target
DB00230PregabalinVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00230PregabalinExcitatory amino acid transporter 3transporter
DB00285VenlafaxineSodium-dependent serotonin transportertarget
DB00285VenlafaxineSodium-dependent noradrenaline transportertarget
DB00285VenlafaxineCytochrome P450 2D6enzyme
DB00285VenlafaxineCytochrome P450 3A4enzyme
DB00285VenlafaxineCytochrome P450 2C9enzyme
DB00285VenlafaxineCytochrome P450 2C19enzyme
DB00285VenlafaxineSodium-dependent dopamine transportertarget
DB00285VenlafaxineMultidrug resistance protein 1transporter
DB00285VenlafaxineCytochrome P450 2B6enzyme
DB00285VenlafaxineATP-binding cassette sub-family G member 2transporter
DrugDrug NamePhaseStatusCount
DB09140Oxygen0Unknown Status1
DB12878AV-1011Completed1
DB01068Clonazepam1Recruiting1
DB00843Donepezil1Completed1
DB00668Epinephrine1Terminated1
DB09119Eslicarbazepine acetate1Completed1
DB01167Itraconazole1Completed1
DB00281Lidocaine1Terminated1
DB00331Metformin1Completed1
DB14158Microcrystalline cellulose1Completed1
DB00230Pregabalin1Recruiting1
DB11706Raxatrigine1Completed2
DB11706Raxatrigine1Terminated1
DB00349Clobazam1 / 2Completed1
DB01068Clonazepam1 / 2Completed1
DB14009Medical Cannabis1 / 2Completed2
DB01036Tolterodine1 / 2Completed1
DB05050ADL58592Completed1
DB12644AZD-20662Terminated1
DB00316Acetaminophen2Recruiting2
DB06151Acetylcysteine2Completed1
DB00083Botulinum toxin type A2Terminated1
DB06774Capsaicin2Recruiting1
DB00482Celecoxib2Recruiting1
DB00514Dextromethorphan2Completed1
DB12140Dilmapimod2Completed1
DB00470Dronabinol2Recruiting1
DB00476Duloxetine2Completed1
DB00476Duloxetine2Recruiting1
DB00668Epinephrine2Completed1
DB00736Esomeprazole2Recruiting1
DB12760GW-4938382Completed1
DB00996Gabapentin2Completed1
DB00996Gabapentin2Withdrawn1
DB00028Immune Globulin Human2Unknown Status1
DB05214KD70402Completed1
DB01221Ketamine2Completed1
DB01221Ketamine2Recruiting1
DB00125L-Arginine2Terminated1
DB06218Lacosamide2Not Yet Recruiting1
DB04465Lactose2Completed1
DB00281Lidocaine2Completed1
DB01356Lithium cation2Completed1
DB12270Losmapimod2Completed1
DB00408Loxapine2Recruiting1
DB00653Magnesium sulfate2Recruiting1
DB14009Medical Cannabis2Recruiting1
DB01043Memantine2Completed1
DB01043Memantine2Not Yet Recruiting1
DB04896Milnacipran2Recruiting1
DB00295Morphine2Recruiting1
DB00486Nabilone2Completed1
DB01183Naloxone2Recruiting1
DB00788Naproxen2Recruiting1
DB00435Nitric Oxide2Completed1
DB00497Oxycodone2Recruiting1
DB00107Oxytocin2Recruiting1
DB00230Pregabalin2Completed1
DB00230Pregabalin2Terminated1
DB00230Pregabalin2Withdrawn1
DB06649Priralfinamide2Completed1
DB05232Tetrodotoxin2Terminated1
DB00193Tramadol2Recruiting1
DB00313Valproic Acid2Completed1
DB06283Ziconotide2Active Not Recruiting1
DB00321Amitriptyline3Recruiting1
DB00083Botulinum toxin type A3Withdrawn1
DB00297Bupivacaine3Not Yet Recruiting1
DB09061Cannabidiol3Completed2
DB00470Dronabinol3Completed2
DB00996Gabapentin3Not Yet Recruiting1
DB00825Levomenthol3Completed1
DB00526Oxaliplatin3Completed1
DB01192Oxymorphone3Completed1
DB00715Paroxetine3Completed1
DB00230Pregabalin3Completed6
DB00230Pregabalin3Terminated1
DB00193Tramadol3Recruiting1
DB11079Trolamine salicylate3Completed1
DB00316Acetaminophen4Not Yet Recruiting1
DB00316Acetaminophen4Recruiting1
DB00083Botulinum toxin type A4Completed1
DB00297Bupivacaine4Not Yet Recruiting1
DB00297Bupivacaine4Recruiting2
DB06774Capsaicin4Not Yet Recruiting1
DB06774Capsaicin4Unknown Status1
DB00564Carbamazepine4Completed1
DB00341Cetirizine4Enrolling by Invitation1
DB01234Dexamethasone4Recruiting1
DB00843Donepezil4Active Not Recruiting1
DB00476Duloxetine4Not Yet Recruiting1
DB00668Epinephrine4Recruiting1
DB00996Gabapentin4Enrolling by Invitation1
DB00327Hydromorphone4Completed1
DB01221Ketamine4Completed1
DB01221Ketamine4Recruiting1
DB01221Ketamine4Unknown Status1
DB01009Ketoprofen4Not Yet Recruiting1
DB01009Ketoprofen4Recruiting1
DB00125L-Arginine4Completed1
DB00281Lidocaine4Completed2
DB00281Lidocaine4Not Yet Recruiting1
DB00281Lidocaine4Terminated1
DB04817Metamizole4Not Yet Recruiting1
DB04817Metamizole4Recruiting1
DB00333Methadone4Completed1
DB00295Morphine4Recruiting1
DB00486Nabilone4Completed1
DB01183Naloxone4Completed1
DB00497Oxycodone4Completed1
DB00497Oxycodone4Terminated1
DB00230Pregabalin4Completed2
DB00230Pregabalin4Not Yet Recruiting1
DB00230Pregabalin4Unknown Status3
DB00296Ropivacaine4Not Yet Recruiting1
DB06204Tapentadol4Completed1
DB00083Botulinum toxin type ANot AvailableCompleted1
DB00921BuprenorphineNot AvailableCompleted1
DB09061CannabidiolNot AvailableCompleted1
DB06774CapsaicinNot AvailableRecruiting4
DB06774CapsaicinNot AvailableUnknown Status1
DB14184CinnamaldehydeNot AvailableRecruiting1
DB01075DiphenhydramineNot AvailableCompleted1
DB00470DronabinolNot AvailableCompleted1
DB00476DuloxetineNot AvailableNot Yet Recruiting1
DB00668EpinephrineNot AvailableCompleted2
DB00813FentanylNot AvailableCompleted1
DB00327HydromorphoneNot AvailableCompleted1
DB00825LevomentholNot AvailableRecruiting1
DB00281LidocaineNot AvailableCompleted2
DB00281LidocaineNot AvailableRecruiting2
DB00653Magnesium sulfateNot AvailableCompleted1
DB00333MethadoneNot AvailableCompleted1
DB09241Methylene blueNot AvailableCompleted1
DB00295MorphineNot AvailableCompleted1
DB00497OxycodoneNot AvailableCompleted1
DB01192OxymorphoneNot AvailableUnknown Status1
DB01229PaclitaxelNot AvailableActive Not Recruiting1
DB00230PregabalinNot AvailableActive Not Recruiting1
DB00230PregabalinNot AvailableCompleted4
DB00230PregabalinNot AvailableNot Yet Recruiting1
DB00230PregabalinNot AvailableRecruiting1
DB00980RamelteonNot AvailableTerminated1
DB06204TapentadolNot AvailableCompleted1
DB00285VenlafaxineNot AvailableCompleted1
DB01593ZincNot AvailableCompleted1