Sickle Cell Disease (SCD)

Also known as: Sickle-Cell Disease / Sickle Cell Disorder / Sickle Cell Disease / Sickle Cells Disease / Sickle Cell Disorders / Sickle-cell anemia, unspecified / Sickle-cell anaemia, unspecified / Sickle-cell disorders / Sickle cell anemia of unspecified type (disorder) / Sickle cell syndrome / Sickle cell anaemia / Anaemia sickle cell / Sickle cell anemia NOS (disorder) / Sickle-cell anaemia / Sickle cell disease NOS / Sickling disorder due to hemoglobin S (disorder) / Sickle-cell anemia / Sickle cell anemia / Hemoglobin S disease / Sickle cell-hemoglobin SS disease (disorder) / Anemia sickle cell / Anemia, Sickle Cell

DrugDrug NameDrug Description
DB15271CrizanlizumabA monoclonal antibody that targets selectin to reduce the frequency of vasooclusive crises in patients with sickle cell disease.
DB14975VoxelotorA drug used to inhibit the polymerization of hemoglobin S, preventing the painful and sometimes lethal vaso-occlusive crises associated with sickle cell disease.
DrugDrug NamePhaseStatusCount
DB00087Alemtuzumab0Recruiting1
DB01005Hydroxyurea0Active Not Recruiting1
DB00619Imatinib0Not Yet Recruiting1
DB00678Losartan0Completed1
DB00331Metformin0Recruiting1
DB00877Sirolimus0Recruiting1
DB00624Testosterone0Withdrawn1
DB01281Abatacept1Completed1
DB01281Abatacept1Recruiting1
DB00316Acetaminophen1Recruiting1
DB03128Acetylcholine1Completed1
DB00945Acetylsalicylic acid1Completed1
DB00087Alemtuzumab1Recruiting2
DB00098Antithymocyte immunoglobulin (rabbit)1Recruiting2
DB00207Azithromycin1Withdrawn1
DB01222Budesonide1Completed1
DB06774Capsaicin1Enrolling by Invitation1
DB00155Citrulline1Completed2
DB00155Citrulline1Unknown Status1
DB00155Citrulline1Withdrawn1
DB00531Cyclophosphamide1Recruiting2
DB00091Cyclosporine1Recruiting1
DB01262Decitabine1Completed1
DB01262Decitabine1Recruiting1
DB08826Deferiprone1Completed1
DB01075Diphenhydramine1Recruiting1
DB00470Dronabinol1Recruiting1
DB00016Erythropoietin1Completed1
DB01073Fludarabine1Completed1
DB01073Fludarabine1Recruiting2
DB01005Hydroxyurea1Completed2
DB01042Melphalan1Recruiting1
DB00454Meperidine1Recruiting1
DB00563Methotrexate1Recruiting1
DB00959Methylprednisolone1Recruiting1
DB14158Microcrystalline cellulose1Completed1
DB00688Mycophenolate mofetil1Recruiting3
DB01024Mycophenolic acid1Recruiting1
DB02701Nicotinamide1Recruiting1
DB09112Nitrous acid1Completed1
DB05262Oxypurinol1Completed1
DB06603Panobinostat1Active Not Recruiting1
DB00552Pentostatin1Recruiting1
DB06809Plerixafor1Completed1
DB06809Plerixafor1Recruiting2
DB06209Prasugrel1Completed1
DB00571Propranolol1Terminated1
DB06213Regadenoson1Completed1
DB01001Salbutamol1Completed1
DB00877Sirolimus1Recruiting2
DB09153Sodium chloride1Completed1
DB00864Tacrolimus1Recruiting2
DB12484Tetrahydrouridine1Completed1
DB12484Tetrahydrouridine1Recruiting1
DB04572Thiotepa1Recruiting1
DB08816Ticagrelor1Completed2
DB11815Tilarginine1Completed1
DB14975Voxelotor1Completed3
DB09145Water1Completed1
DB00744Zileuton1Completed1
DB06151Acetylcysteine1 / 2Enrolling by Invitation1
DB00087Alemtuzumab1 / 2Active Not Recruiting1
DB00087Alemtuzumab1 / 2Recruiting3
DB15164Apadamtase alfa1 / 2Active Not Recruiting1
DB00125Arginine1 / 2Suspended1
DB00207Azithromycin1 / 2Withdrawn1
DB01008Busulfan1 / 2Recruiting1
DB15572CTX0011 / 2Recruiting1
DB00169Cholecalciferol1 / 2Completed1
DB00318Codeine1 / 2Completed1
DB00531Cyclophosphamide1 / 2Recruiting1
DB00091Cyclosporine1 / 2Active Not Recruiting1
DB00746Deferoxamine1 / 2Not Yet Recruiting1
DB03756Doconexent1 / 2Terminated1
DB00063Eptifibatide1 / 2Terminated1
DB13961Fish oil1 / 2Terminated1
DB01073Fludarabine1 / 2Active Not Recruiting1
DB01073Fludarabine1 / 2Recruiting1
DB11242Gelatin1 / 2Terminated1
DB00028Human immunoglobulin G1 / 2Recruiting1
DB01005Hydroxyurea1 / 2Active Not Recruiting1
DB01005Hydroxyurea1 / 2Completed1
DB01005Hydroxyurea1 / 2Terminated1
DB00159Icosapent1 / 2Terminated1
DB14009Medical Cannabis1 / 2Completed1
DB01042Melphalan1 / 2Active Not Recruiting1
DB00688Mycophenolate mofetil1 / 2Active Not Recruiting1
DB09112Nitrous acid1 / 2Terminated1
DB00552Pentostatin1 / 2Recruiting1
DB06809Plerixafor1 / 2Active Not Recruiting1
DB06809Plerixafor1 / 2Recruiting1
DB12544Rivipansel1 / 2Completed1
DB00641Simvastatin1 / 2Active Not Recruiting1
DB00641Simvastatin1 / 2Completed2
DB00877Sirolimus1 / 2Recruiting3
DB00864Tacrolimus1 / 2Active Not Recruiting1
DB04572Thiotepa1 / 2Recruiting1
DB11094Vitamin D1 / 2Completed1
DB14975Voxelotor1 / 2Not Yet Recruiting1
DB00399Zoledronic acid1 / 2Withdrawn1
DB00054Abciximab2Withdrawn1
DB03128Acetylcholine2Completed1
DB00087Alemtuzumab2Active Not Recruiting2
DB00087Alemtuzumab2Completed2
DB00087Alemtuzumab2Recruiting5
DB00087Alemtuzumab2Terminated1
DB09312Antilymphocyte immunoglobulin (horse)2Completed2
DB00098Antithymocyte immunoglobulin (rabbit)2Active Not Recruiting2
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)2Terminated2
DB00125Arginine2Suspended1
DB01076Atorvastatin2Completed1
DB00993Azathioprine2Recruiting1
DB00921Buprenorphine2Enrolling by Invitation1
DB01008Busulfan2Active Not Recruiting2
DB01008Busulfan2Completed4
DB01008Busulfan2Terminated1
DB00169Cholecalciferol2Active Not Recruiting1
DB00169Cholecalciferol2Not Yet Recruiting1
DB00169Cholecalciferol2Unknown Status1
DB09110Coenzyme M2Active Not Recruiting1
DB15271Crizanlizumab2Active Not Recruiting1
DB15271Crizanlizumab2Recruiting1
DB15271Crizanlizumab2Suspended1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00531Cyclophosphamide2Completed2
DB00531Cyclophosphamide2Recruiting5
DB00531Cyclophosphamide2Terminated3
DB06779Dalteparin2Completed1
DB01262Decitabine2Completed1
DB01609Deferasirox2Completed2
DB00746Deferoxamine2Completed1
DB04932Defibrotide2Recruiting2
DB03756Doconexent2Active Not Recruiting1
DB00813Fentanyl2Withdrawn1
DB00099Filgrastim2Active Not Recruiting1
DB01073Fludarabine2Active Not Recruiting3
DB01073Fludarabine2Completed3
DB01073Fludarabine2Recruiting5
DB01073Fludarabine2Terminated2
DB00996Gabapentin2Completed1
DB01109Heparin2Terminated1
DB00327Hydromorphone2Withdrawn1
DB01005Hydroxyurea2Active Not Recruiting3
DB01005Hydroxyurea2Recruiting4
DB01050Ibuprofen2Withdrawn1
DB01221Ketamine2Recruiting1
DB01221Ketamine2Terminated1
DB00130L-Glutamine2Completed1
DB01202Levetiracetam2Terminated1
DB00678Losartan2Recruiting1
DB08932Macitentan2Completed1
DB14009Medical Cannabis2Recruiting1
DB01042Melphalan2Active Not Recruiting1
DB01042Melphalan2Completed1
DB01042Melphalan2Recruiting2
DB01043Memantine2Recruiting1
DB00563Methotrexate2Active Not Recruiting1
DB00764Mometasone2Recruiting1
DB14512Mometasone furoate2Completed1
DB00295Morphine2Withdrawn1
DB00688Mycophenolate mofetil2Recruiting2
DB00688Mycophenolate mofetil2Terminated2
DB01183Naloxone2Enrolling by Invitation1
DB00627Niacin2Completed1
DB00435Nitric Oxide2Completed1
DB00435Nitric Oxide2Terminated2
DB09112Nitrous acid2Recruiting1
DB06690Nitrous oxide2Recruiting1
DB15238Olinciguat2Active Not Recruiting1
DB09140Oxygen2Terminated1
DB00552Pentostatin2Recruiting1
DB06809Plerixafor2Recruiting1
DB06209Prasugrel2Completed1
DB00571Propranolol2Completed1
DB01220Rifaximin2Recruiting1
DB08931Riociguat2Recruiting1
DB00073Rituximab2Terminated1
DB12544Rivipansel2Completed1
DB00360Sapropterin2Completed1
DB06280Senicapoc2Completed1
DB15007Sevuparin2Completed1
DB00203Sildenafil2Terminated2
DB00877Sirolimus2Active Not Recruiting1
DB00877Sirolimus2Recruiting6
DB00877Sirolimus2Terminated2
DB09153Sodium chloride2Withdrawn1
DB09422Soybean oil2Active Not Recruiting1
DB00864Tacrolimus2Active Not Recruiting1
DB00864Tacrolimus2Terminated1
DB04572Thiotepa2Active Not Recruiting1
DB04572Thiotepa2Completed1
DB04572Thiotepa2Recruiting2
DB08816Ticagrelor2Completed1
DB11815Tilarginine2Completed1
DB03904Urea2Recruiting1
DB05737Varespladib methyl2Terminated1
DB11094Vitamin D2Unknown Status1
DB02546Vorinostat2Completed1
DB14975Voxelotor2Completed1
DB14975Voxelotor2Recruiting2
DB00087Alemtuzumab2 / 3Completed1
DB01008Busulfan2 / 3Completed1
DB00608Chloroquine2 / 3Active Not Recruiting1
DB00531Cyclophosphamide2 / 3Completed1
DB01609Deferasirox2 / 3Unknown Status1
DB08826Deferiprone2 / 3Unknown Status1
DB00746Deferoxamine2 / 3Unknown Status1
DB00099Filgrastim2 / 3Completed1
DB01073Fludarabine2 / 3Completed1
DB00158Folic acid2 / 3Recruiting1
DB00653Magnesium sulfate2 / 3Completed1
DB00295Morphine2 / 3Recruiting1
DB00435Nitric Oxide2 / 3Completed1
DB11133Omega-3 fatty acids2 / 3Recruiting1
DB00641Simvastatin2 / 3Recruiting1
DB03904Urea2 / 3Recruiting1
DB09322Zinc sulfate2 / 3Recruiting1
DB06151Acetylcysteine3Completed1
DB00087Alemtuzumab3Active Not Recruiting1
DB06605Apixaban3Terminated1
DB00125Arginine3Completed1
DB15271Crizanlizumab3Recruiting1
DB01609Deferasirox3Completed1
DB03756Doconexent3Not Yet Recruiting1
DB01073Fludarabine3Active Not Recruiting1
DB00327Hydromorphone3Recruiting1
DB01005Hydroxyurea3Active Not Recruiting1
DB01005Hydroxyurea3Completed3
DB01005Hydroxyurea3Recruiting1
DB01221Ketamine3Not Yet Recruiting2
DB01042Melphalan3Active Not Recruiting1
DB00422Methylphenidate3Completed1
DB00959Methylprednisolone3Completed1
DB00295Morphine3Completed1
DB00295Morphine3Recruiting1
DB00844Nalbuphine3Completed1
DB11333Poloxamer 1883Completed2
DB06209Prasugrel3Terminated1
DB00635Prednisone3Completed1
DB12544Rivipansel3Terminated1
DB12778Rivipansel3Terminated1
DB06280Senicapoc3Terminated2
DB09422Soybean oil3Not Yet Recruiting1
DB08816Ticagrelor3Active Not Recruiting1
DB08816Ticagrelor3Not Yet Recruiting1
DB14975Voxelotor3Active Not Recruiting1
DB14975Voxelotor3Completed1
DB14975Voxelotor3Enrolling by Invitation1
DB14975Voxelotor3Recruiting1
DB00173Adenine4Completed1
DB00318Codeine4Withdrawn1
DB01609Deferasirox4Completed1
DB08826Deferiprone4Enrolling by Invitation1
DB08826Deferiprone4Recruiting1
DB00746Deferoxamine4Completed1
DB00746Deferoxamine4Recruiting1
DB00514Dextromethorphan4Withdrawn1
DB01452Diamorphine4Terminated1
DB00294Etonogestrel4Active Not Recruiting1
DB00813Fentanyl4Completed1
DB00327Hydromorphone4Completed1
DB01005Hydroxyurea4Active Not Recruiting1
DB01005Hydroxyurea4Completed1
DB01050Ibuprofen4Terminated1
DB04335Inosine4Completed1
DB01221Ketamine4Terminated1
DB00295Morphine4Completed2
DB00295Morphine4Terminated1
DB00295Morphine4Withdrawn1
DB11194Pyruvic acid4Completed1
DB14504Sodium phosphate, dibasic, unspecified form4Completed1
DB09449Sodium phosphate, monobasic4Completed1
DB09525Sodium phosphate, monobasic4Completed1
DB00163Vitamin E4Active Not Recruiting1
DB14975Voxelotor4Not Yet Recruiting1
DB00819AcetazolamideNot AvailableRecruiting2
DB00092AlefaceptNot AvailableTerminated1
DB00087AlemtuzumabNot AvailableTerminated1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableRecruiting1
DB01008BusulfanNot AvailableTerminated1
DB15572CTX001Not AvailableEnrolling by Invitation1
DB09110Coenzyme MNot AvailableRecruiting1
DB09110Coenzyme MNot AvailableTerminated1
DB15271CrizanlizumabNot AvailableAvailable1
DB00531CyclophosphamideNot AvailableRecruiting1
DB00531CyclophosphamideNot AvailableTerminated1
DB09341Dextrose, unspecified formNot AvailableTerminated1
DB00584EnalaprilNot AvailableTerminated1
DB01073FludarabineNot AvailableRecruiting1
DB00158Folic acidNot AvailableCompleted1
DB01005HydroxyureaNot AvailableCompleted4
DB01005HydroxyureaNot AvailableRecruiting1
DB14444Influenza A virus A/California/7/2009 (H1N1)-like antigen (propiolactone inactivated)Not AvailableCompleted1
DB01221KetamineNot AvailableRecruiting1
DB01221KetamineNot AvailableTerminated1
DB00333MethadoneNot AvailableCompleted1
DB00295MorphineNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableRecruiting1
DB00417PhenoxymethylpenicillinNot AvailableCompleted1
DB01131ProguanilNot AvailableCompleted1
DB06213RegadenosonNot AvailableActive Not Recruiting1
DB00877SirolimusNot AvailableRecruiting1
DB14975VoxelotorNot AvailableApproved for Marketing1