Cytochrome P-450 CYP3A5 Substrates

DrugDrug NameDrug Indication
DB00091CyclosporineFor treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis.
DB00224IndinavirIndinavir is an antiretroviral drug for the treatment of HIV infection.
DB00468QuinineFor the treatment of malaria and leg cramps
DB00541VincristineTreatment of acute lymphocytic leukemia (ALL), Hodgkin lymphoma, non-Hodgkin lymphomas, Wilms' tumor, neuroblastoma, rhabdomyosarcoma. Liposomal vincristine is indicated for the treatment of relapsed Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL).
DB00661VerapamilFor the treatment of hypertension, angina, and cluster headache prophylaxis.
DB00683MidazolamThe midazolam injection is indicated for preoperative sedation/anziolysis/amnesia. It is also an agent for sedation/anziolysis/amnesia prior to or during diagnostic, therapeutic, or endoscopic procedures. Midazolam can also be given intravenously for induction of general anaesthesia.
DB00864TacrolimusFor use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, and limb transplants. It has also been used in a topical preparation in the treatment of severe atopic dermatitis.
DB01232SaquinavirFor the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.
DB00802AlfentanilFor the management of postoperative pain and the maintenance of general anesthesia.
DB00203SildenafilFor the treatment of erectile dysfunction and to relieve symptoms of pulmonary arterial hypertension (PAH).
DB00619ImatinibFor the treatment of Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), Ph+ acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome and/or chronic eosinophilic leukemia (CEL), dermatofibrosarcoma protuberans, and malignant gastrointestinal stromal tumors (GIST).
DB00675TamoxifenTamoxifen is indicated for the treatment of metastatic breast cancer in women and men and ductal carcinoma in Situ.
DB00238NevirapineFor use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.
DB01211ClarithromycinAn alternative medication for the treatment of acute otitis media caused by H. influenzae, M. catarrhalis, or S. pneumoniae in patients with a history of type I penicillin hypersensitivity. Also for the treatment of pharyngitis and tonsillitis caused by susceptible Streptococcus pyogenes, as well as respiratory tract infections including acute maxillary sinusitis, acute bacterial exacerbations of chronic bronchitis, mild to moderate community-acquired pneuomia, Legionnaires' disease, and pertussis. Other indications include treatment of uncomplicated skin or skin structure infections, helicobacter pylori infection, duodenal ulcer disease, bartonella infections, early Lyme disease, and encephalitis caused by Toxoplasma gondii (in HIV infected patients in conjunction with pyrimethamine). Clarithromycin may also decrease the incidence of cryptosporidiosis, prevent the occurence of α-hemolytic (viridans group) streptococcal endocarditis, as well as serve as a primary prevention for Mycobacterium avium complex (MAC) bacteremia or disseminated infections (in adults, adolescents, and children with advanced HIV infection).
DB00976TelithromycinFor the treatment of Pneumococcal infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respiratory tract infection and lobar (pneumococcal) pneumonia.
DB00404AlprazolamFor the management of anxiety disorder or the short-term relief of symptoms of anxiety and for the treatment of panic disorder, with or without agoraphobia.
DB00829DiazepamUsed in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.
DB00897TriazolamFor the short-term treatment of insomnia.
DB00604CisaprideFor the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
DB00637AstemizoleAstemizole was indicated for use in the relieving allergy symptoms, particularly rhinitis and conjunctivitis. It has been withdrawn from the market however due to concerns of arrhythmias.
DB01114ChlorphenamineFor the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.
DB00381AmlodipineFor the treatment of hypertension and chronic stable angina.
DB00343DiltiazemFor the treatment of Hypertension
DB01023FelodipineFor the treatment of mild to moderate essential hypertension.
DB01115NifedipineFor the management of vasospastic angina, chronic stable angina, hypertension, and Raynaud's phenomenon. May be used as a first line agent for left ventricular hypertrophy and isolated systolic hypertension (long-acting agents).
DB00401NisoldipineFor the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
DB01054NitrendipineFor the treatment of mild to moderate hypertension
DB01076AtorvastatinMay be used as primary prevention in individuals with multiple risk factors for coronary heart disease (CHD) and as secondary prevention in individuals with CHD to reduce the risk of myocardial infarction (MI), stroke, angina, and revascularization procedures. May be used to reduce the risk of cardiovascular events in patients with acute coronary syndrome (ACS). May be used in the treatment of primary hypercholesterolemia and mixed dyslipidemia, homozygous familial hypercholesterolemia, primary dysbetalipoproteinemia, and/or hypertriglyeridemia as an adjunct to dietary therapy to decrease serum total and low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB), and triglyceride concentrations, while increasing high-density lipoprotein cholesterol (HDL-C) levels.
DB00227LovastatinFor management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia. For primary prevention of coronary heart disease and to slow progression of coronary atherosclerosis in patients with coronary heart disease.
DB00641SimvastatinFor the treatment of hypercholesterolemia and for the reduction in the risk of cardiac heart disease mortality and cardiovascular events. It can also be used in adolescent patients for the treatment of heterozygous familial hypercholesterolemia.
DB01238AripiprazoleFor the treatment of schizophrenia and related psychotic disorders.
DB00490BuspironeFor the management of anxiety disorders or the short-term relief of the symptoms of anxiety, and also as an augmention of SSRI-treatment against depression.
DB00502HaloperidolFor the treatment of schizophrenia [L2016] For the treatment of acute psychosis in acutely agitated schizophrenic patients with moderately severe to very severe symptoms [L2016] For the treatment of severe behavioral or psychological symptoms of dementia [L2016] For the treatment of delirium in the pediatric intensive care unit [L2016] For the treatment of agitation or delirium [L2016] For agitation† or delirium in adult patients with no underlying psychiatric illness [L2016] For use as a second-line agent for rescue treatment of chemotherapy-induced nausea/vomiting [L2016] For the treatment of irritability associated with autistic disorder [L2016] For the treatment of tics and vocal utterances associated with Tourette's syndrome [L2016] For the treatment of severe behavioral problems associated with oppositional defiant disorder or other disruptive behavioral disorders, or for the treatment of attention-deficit hyperactivity disorder (ADHD) in pediatric patients who show excessive motor activity with accompanying conduct disorders [L2016]
DB01100PimozideUsed for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
DB00877SirolimusFor the prophylaxis of organ rejection in patients receiving renal transplants.
DB00656TrazodoneFor the treatment of depression.
DB00175PravastatinFor the treatment of hypercholesterolemia and to reduce the risk of cardiovascular disease.
DB00862VardenafilUsed for the treatment of erectile dysfunction
DB08873BoceprevirBoceprevir, when used in combination with [DB00811], [DB00008], and [DB00022] is indicated for use in the treatment of chronic HCV genotype 1 infection in adults [FDA Label].
DB00503RitonavirIndicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
DB06267UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
DB00741HydrocortisoneFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14538Hydrocortisone aceponateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14539Hydrocortisone acetateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14540Hydrocortisone butyrateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14541Hydrocortisone cypionateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14542Hydrocortisone phosphateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14543Hydrocortisone probutateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB14545Hydrocortisone succinateNot Available
DB14544Hydrocortisone valerateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
DB06789Hydroxyprogesterone caproateHydroxyprogesterone caproate is indicated for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. (1)
DB00717NorethisteroneFor the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer.
DB00396ProgesteroneFor progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used for the reduction of the incidence of endometrial hyperplasia and the attendant risk of endometrial carcinoma in postmenopausal women receiving estrogen replacement therapy, as well as treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology such as fibroids or uterine cancer.
DB09068VortioxetineVortioxetine is indicated for the treatment of major depressive disorder (MDD).
DB08883PerampanelUsed in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
DB08865CrizotinibCrizotinib is used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic-lymphoma kinase (ALK)-positive as detected by a FDA-approved test.
DB06626AxitinibUsed in kidney cell cancer and investigated for use/treatment in pancreatic and thyroid cancer.
DB01267PaliperidoneFor the treatment of schizophrenia.
DB01259LapatinibIndicated in combination with capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress the human epidermal receptor type 2 (HER2) protein and who have received prior therapy including an anthracycline, a taxane, and trastuzuma.
DB11737IcotinibIcotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
DB00472FluoxetineLabeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon.
DB00734RisperidoneRisperidone belongs to the class of medications known as ​second generation atypical antipsychotics [A1114, A1115, L1213]. It is widely used in the treatment of schizophrenia and mood disorders, including bipolar disorder and depression with pyschosis [A1115, A1116, L1212, L1213].
DB09297ParitaprevirWhen used within the fixed-dose combination product with [DB09296], [DB09183], and [DB00503] as the FDA-approved product Viekira Pak, paritaprevir is indicated for the treatment of HCV genotype 1b without cirrhosis or with compensated cirrhosis, and when combined with [DB00811] for the treatment of HCV genotype 1a without cirrhosis or with compensated cirrhosis. When used within the fixed-dose combination product with [DB09296] and [DB00503] as the FDA- and Health Canada-approved product Technivie, paritaprevir is indicated in combination with [DB00811] for the treatment of patients with genotype 4 chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis. When used within the fixed-dose combination product with [DB09296], [DB09183], and [DB00503] as the Health Canada-approved, commercially available product Holkira Pak, paritaprevir is indicated for the treatment of HCV genotype 1b with or without cirrhosis, and when combined with [DB00811] for the treatment of HCV genotype 1a with or without cirrhosis.
DB00813FentanylFor the treatment of cancer patients with severe pain that breaks through their regular narcotic therapy.
DB06287TemsirolimusFor the treatment of renal cell carcinoma (RCC). Also investigated for use/treatment in breast cancer, lymphoma (unspecified), rheumatoid arthritis, and multiple myeloma.
DB01098RosuvastatinUsed as an adjunct to dietary therapy to treat primary hyperlipidemia (heterozygous familial and nonfamilial), mixed dyslipidemia and hypertriglyceridemia. Also indicated for homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering therapies or when other such therapies are not available. Furthermore, it is used to slow the progression of atherosclerosis and for primary prevention of cardiovascular disease.
DB00393NimodipineFor use as an adjunct to improve neurologic outcome following subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms by reducing the incidence and severity of ischemic deficits.
DB00909ZonisamideFor use as adjunctive treatment of partial seizures in adults with epilepsy.
DB01095FluvastatinTo be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia.
DB00758ClopidogrelFor the reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by recent stroke, recent myocardial infarction, or established peripheral arterial disease.
DB00762IrinotecanFor the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combination with cisplatin for the treatment of extensive small cell lung cancer. Irinotecan is currently under investigation for the treatment of metastatic or recurrent cervical cancer. Also used in combination with fluorouracil and leucovorin for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy.
DB00834MifepristoneFor the medical termination of intrauterine pregnancy through 49 days' pregnancy. Also indicated to control hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and are not candidates for surgery or have had unsuccessful surgery.
DB01181IfosfamideUsed as a component of various chemotherapeutic regimens as third-line therapy for recurrent or refractory germ cell testicular cancer. Also used as a component of various chemotherapeutic regimens for the treatment of cervical cancer, as well as in conjunction with surgery and/or radiation therapy in the treatment of various soft tissue sarcomas. Other indications include treatment of osteosarcoma, bladder cancer, ovarian cancer. small cell lung cancer, and non-Hodgkin's lymphoma.
DB00321Amitriptyline- Indicated for the treatment of major depressive disorder in adults - Indicated for the management of neuropathic pain in adults - Indicated for the prophylactic treatment of chronic tension type headache (CTTH) in adults - Indicated for the prophylactic treatment of migraine in adults - Indicated for the the treatment of nocturnal enuresis in children aged 6 years and above when organic pathology, including spina bifida and related disorders, have been excluded and no response has been achieved to all other non-drug and drug treatments, including antispasmodics and vasopressin-related products. This medicinal product should only be prescribed by a healthcare professional with expertise in the management of persistent enuresis. -Other off-label uses include irritable bowel syndrome, sleep disorders, diabetic neuropathy, agitation and insomnia
DB00540NortriptylinePrimarily indicated for the relief of symptoms of depression.
DB06652VicrivirocInvestigated for use/treatment in HIV infection and viral infection.
DB00972AzelastineFor the symptomatic treatment of seasonal allergic rhinitis and non-allergic rhinitis, as well as symptomatic relief of ocular itching associated with allergic conjunctivitis.
DB00342TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00528LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
DB00439CerivastatinUsed as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
DB00783EstradiolEstradiol is indicated for the treatment of moderate to severe vasomotor symptoms and vulvar and vaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure, and for the prevention of post-menopausal osteoarthritis. It is also used for the treatment of breast cancer (for palliation only) in appropriately selected women and men with metastatic disease, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only).
DB00624TestosteroneTo be used as hormone replacement or substitution of diminished or absent endogenous testosterone. Use in males: For management of congenital or acquired hypogonadism, hypogonadism associated with HIV infection, and male climacteric (andopause). Use in females: For palliative treatment of androgen-responsive, advanced, inoperable, metastatis (skeletal) carcinoma of the breast in women who are 1-5 years postmenopausal; testosterone esters may be used in combination with estrogens in the management of moderate to severe vasomotor symptoms associated with menopause in women who do not respond to adequately to estrogen therapy alone.
DB00673AprepitantFor the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy, including high-dose cisplatin (in combination with other antiemetic agents).
DB00201CaffeineFor management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
DB01166CilostazolFor the reduction of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).
DB00907CocaineFor the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
DB00318CodeineFor treatment and management of pain (systemic). It is also used as an antidiarrheal and as a cough suppressant.
DB00250DapsoneFor the treatment and management of leprosy and dermatitis herpetiformis.
DB00514DextromethorphanFor treatment and relief of dry cough.
DB01248DocetaxelFor the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy. Also used as a single agent in the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of prior platinum-based chemotherapy. It is also used in combination with prednisone, in the treatment of patients with androgen independent (hormone refractory) metastatic prostate cancer. Furthermore, docetaxel has uses in the treatment of gastric adenocarinoma and head and neck cancer.
DB01184DomperidoneFor management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
DB00700EplerenoneFor improvement of survival of stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and clinical evidence of congestive heart failure after an acute myocardial infarction.
DB01216FinasterideFor the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostate. Also used for the stimulation of regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness).
DB01227Levomethadyl acetateFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
DB00281LidocaineFor production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
DB00333MethadoneFor the treatment of dry cough, drug withdrawal syndrome, opioid type drug dependence, and pain.
DB00731NateglinideFor the treatment of non-insulin dependent-diabetes mellitus in conjunction with diet and exercise.
DB00904OndansetronFor the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment of postoperative nausea and vomiting.
DB00571PropranololFor the prophylaxis of migraine.
DB01224QuetiapineFor the treatment of schizophrenia and related psychotic disorders.
DB00938SalmeterolFor the treatment of asthma and chronic obstructive pulmonary disease (COPD).
DB00398SorafenibSorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma.
DB01268SunitinibFor the treatment of advanced renal cell carcinoma as well as the treatment of gastrointestinal stromal tumor after disease progression on or intolerance to imatinib mesylate.
DB01229PaclitaxelUsed in the treatment of Kaposi's sarcoma and cancer of the lung, ovarian, and breast. Abraxane® is specfically indicated for the treatment of metastatic breast cancer and locally advanced or metastatic non-small cell lung cancer.
DB00962ZaleplonFor the treatment of short-term treatment of insomnia in adults.
DB00246ZiprasidoneFor the treatment of schizophrenia and related psychotic disorders.
DB00425ZolpidemFor the short-term treatment of insomnia.
DB00921BuprenorphineFor the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
DB06772CabazitaxelFor treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
DB06697ArtemetherArtemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified. Indicated for use in adults and children greater than 5 kg.
DB00701AmprenavirFor the treatment of HIV-1 infection in combination with other antiretroviral agents.
DB00278ArgatrobanArgatroban is indicated for prevention and treatment of thrombosis caused by heparin induced thrombocytopenia (HIT). It is also indicated for use in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention.
DB00608ChloroquineFor the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis
DB00822DisulfiramFor the treatment and management of chronic alcoholism
DB00655EstroneFor management of perimenopausal and postmenopausal symptoms.
DB00773EtoposideFor use in combination with other chemotherapeutic agents in the treatment of refractory testicular tumors and as first line treatment in patients with small cell lung cancer. Also used to treat other malignancies such as lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme.
DB00499FlutamideFor the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate
DB01218HalofantrineFor treatment of Severe malaria
DB01103QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
DB01062OxybutyninFor the treatment of overactive bladder.
DB00497OxycodoneFor the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
DB01058PraziquantelFor the treatment of infections due to all species of schistosoma.
DB00444TeniposideTeniposide is used for the treatment of refractory acute lymphoblastic leukaemia
DB00530ErlotinibFor the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen. Also for use, in combination with gemcitabine, as the first-line treatment of patients with locally advanced, unresectable or metastatic pancreatic cancer.
DB00588Fluticasone propionateFluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma.
DB00755TretinoinFor the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage.
DB01254DasatinibFor the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia with resistance or intolerance to prior therapy. Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy.
DB04946IloperidoneTreatment of acute schizophrenia.
DB06176RomidepsinFor the treatment of cutaneous T-cell lymphoma (CTCL) or/and peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior systemic therapy. These indications are based on response rate. Clinical benefit such as improvement in overall survival has not been demonstrated.
DB06335SaxagliptinTreatment of type 2 diabetes mellitus to improve glycemic control in combination with other agents or as monotherapy.
DB00575ClonidineMay be used as an adjunct in the treatment of hypertension, as an epidural infusion as an adjunct treatment in the management of severe cancer pain that is not relieved by opiate analgesics alone, for differential diagnosis of pheochromocytoma in hypertensive patients, prophylaxis of vascular migraine headaches, treatment of severe dysmenorrhea, management of vasomotor symptoms associated with menopause, rapid detoxification in the management of opiate withdrawal, treatment of alcohol withdrawal used in conjunction with benzodiazepines, management of nicotine dependence, topical use to reduce intraocular pressure in the treatment of open-angle and secondary glaucoma and hemorrhagic glaucoma associated with hypertension, and in the treatment of attention-deficit hyperactivity disorder (ADHD).
DB06419CethromycinInvestigated for use/treatment in bacterial infection, pediatric indications, and pneumonia.
DB06228RivaroxabanRivaroxaban is indicated for the prevention of venous thromboembolic events (VTE) in patients who have undergone total hips replacements and total knee replacement surgery; prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE); to reduce risk of recurrent DVT and/or PE. Rivaroxaban is also indicated, in combination with aspirin, for reducing the risk of major cardiovascular events in patients with chronic coronary artery disease or peripheral artery disease. Due to a lack of safety studies, it is not recommended for use in those under 18 years old. Its use is also not recommended in those with severe renal impairment (<30mL/min).
DB06605ApixabanApixaban is to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It has also been used to lower the risk of developing venous thrombosis post-orthopedic surgical procedures.
DB08901PonatinibPonatinib is indicated for the treatment of adult patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy.
DB05773Trastuzumab emtansineUsed in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic disease or had their cancer recur within 6 months of adjuvant treatment.
DB00531CyclophosphamideCyclophosphamide is indicated for the treatment of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. It is also indicated for the treatment of biopsy-proven minimal change nephrotic syndrome in pediatric patients.
DB00688Mycophenolate mofetilFor the prophylaxis of organ rejection in patients receiving allogeneic renal, cardiac or hepatic transplants. Mycophenolate mofetil should be used concomitantly with cyclosporine and corticosteroids.
DB09053IbrutinibIbrutinib acquired an accelerated approval for the treatment of mantle cell lymphoma who have received at least one prior therapy.[FDA label] Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma that develops in the outer edge of a lymph node. MCL is usually diagnosed at late stages and it is easily spread into bone marrow, spleen, liver and gastrointestinal tract.[L1929] Ibrutinib is indicated for the treatment of chronic lymphocytic leukemia (CLL) who have at least one prior therapy.[FDA label] CLL is a type of cancer caused by an overproduction of lymphocytes by the bone marrow. Some of the symptoms include swollen lymph nodes and tiredness.[L1931] Ibrutinib is indicated for the treatment of chronic lymphocytic leukemia (CLL) with 17p deletion.[FDA label] CLL with 17p is a type of leukemia in which a deletion in 17p disrupts the tumor suppressor p53 by deleting one allele of the TP53 gene. The remaining allele is mainly inactivated and thus, this type of leukemia is unresponsive to p53-dependent treatments.[A32305] Ibrutinib is indicated for the treatment of patients with Waldenstrom's Macroglobulinemia (WM).[FDA label] WM, also called lymphoplasmacytic lymphoma, is a type of non-Hodgkin lymphoma in which the cancer cells make large amounts of macroglobulin. The macroglobulin is a monoclonal protein that corresponds to the type of IgM antibodies and the unrestricted formation of this protein causes typical symptoms such as excessive bleeding and effects in vision and nervous system.[L1934]
DB09102DaclatasvirIndicated for use with sofosbuvir, with or without ribavirin, for the treatment of chronic HCV genotype 1a/b or 3 infection. The dosing regimen of 60mg daclatasvir 60 mg with 400mg sofosbuvir once a day is recommended for both genontypes. Resistance: Reduced susceptibility to daclatasvir was associated with the polymorphisms at NS5A amino acid positions M28, Q30, L31, and Y93 in genotypes 1a, 1b, and 3a patients. NS5A Resistance Testing is recommended for HCV genotype 1a-infected patients with cirrhosis prior to the initiaition of the treatment, as the risk of resistance development is higher in genotype 1a patients.
DB06403AmbrisentanAmbrisentan is indicated for treatment of idiopathic (‘primary’) pulmonary arterial hypertension (IPAH) and pulmonary arterial hypertension (PAH) associated with connective tissue disease in patients with WHO functional class II or III symptoms. In the United States of America, ambrisentan is also indicated in combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability.
DB12161DeutetrabenazineIndicated for the treatment of chorea associated with Huntington’s disease [FDA Label].
DB11915ValbenazineFor the treatment of tardive dyskinesia in adults [FDA Label].
DB08820IvacaftorWhen used as monotherapy as the product Kalydeco, ivacaftor is indicated for the managmenet of CF in patients age 2 years and older who have a mutation in the CFTR gene that is responsive to ivacaftor potentiation. Ivacaftor received expanded approval in May 2017 for the following 33 CFTR mutations: E56K, P67L, R74W, D110E, D110H, R117C, R117H, G178R, E193K, L206W, R347H, R352Q, A455E, S549N, S549R, G551D, G551S, D579G, S945L, S977F, F1052V, K1060T, A1067T, G1069R, R1070Q, R1070W, F1074L, D1152H, G1244E, S1251N, S1255P, D1270N, and G1349D [L768, FDA Label]. When used in combination with the drug [DB09280] as the product Orkambi, ivacaftor is indicated for the management of CF patients age 6 years and older who are homozygous for the F508del mutation in the CFTR gene.
DB09054IdelalisibIdelalisib is indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other co-morbidities, while in the treatment of FL and SLL it is intended to be used in patients who have received at least two prior systemic therapies.
DB09065CobicistatCobicistat is a CYP3A inhibitor indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 infection. It is not interchangeable with ritonavir to increase systemic exposure of darunavir 600 mg twice daily, fosamprenavir, saquinavir, or tipranavir due to lack of exposure data. The use of cobicistat is not recommended with darunavir 600 mg twice daily, fosamprenavir, saquinavir or tipranavir. Complex or unknown mechanisms of drug interactions preclude extrapolation of ritonavir drug interactions to certain cobicistat interactions. Cobicistat and ritonavir when administered with either atazanavir or darunavir may result in different drug interactions when used with concomitant medications.
DB11574ElbasvirElbasvir, when used in combination with [DB11575] as the combination product Zepatier, is indicated for use with or without ribavirin for the treatment of chronic HCV genotypes 1 or 4 infection in adults [FDA Label].
DB12483CopanlisibIndicated for the treatment of adult patients with relapsed follicular lymphoma (FL) who have received at least two prior systemic therapies.
DB13943Testosterone cypionateTestosterone cypionate is used in males that present conditions derived from a deficiency or absence of endogenous testosterone. These conditions are 1) primary hypogonadism, defined as the testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; and 2) hypogonadotropic hypogonadism characterized by idiopathic gonadotropin, LHRH deficiency or pituitary-hypothalamic injury from tumors, trauma or radiation.[L1153]
DB13944Testosterone enanthateTestosterone enanthate in males is indicated as a replacement therapy in conditions associated with a deficiency or absence of endogenous testosterone. Some of the treated conditions are 1) primary hypogonadism, defined as testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; 2) hypogonadotropic hypogonadism due to an idiopathic gonadotropin or luteinizing hormone-releasing hormone deficiency or due to a pituitary-hypothalamic injury from tumors, trauma or radiation, in this case it is important to accompany the treatment with adrenal cortical and thyroid hormone replacement therapy; 3) to stimulate puberty in patients with delayed puberty not secondary to a pathological disorder. If the conditions 1 and 2 occur prior to puberty, the androgen replacement therapy will be needed during adolescent years for the development of secondary sexual characteristics and prolonged androgen treatment might be needed it to maintain sexual characteristics after puberty.[FDA label] In females, testosterone enanthate is indicated to be used secondarily in presence of advanced inoperable metastatic mammary cancer in women who are from one to five years postmenopausal. It has also been used in premenopausal women with breast cancer who have benefited from oophorectomy and are considered to have a hormone-responsive tumor.[FDA label] Testosterone enanthate injections that are currently formulated for subcutaneous use are specifically indicated only for primary hypogonadism and hypogonadotropic hypogonadism [F1941]. The use of such formulations is limited because the safety and efficacy of these subcutaneous products in adult males with late-onset hypogonadism and males less than 18 years old have not yet been established [F1941]. Moreover, subcutaneously administered testosterone enanthate is indicated only for the treatment of men with hypogonadal conditions associated with structural or genetic etiologies, considering the medication could cause blood pressure increases that can raise the risk of major adverse cardiovascular events like non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death [F1941].
DB13946Testosterone undecanoateTestosterone undecanoate is indicated as a testosterone replacement therapy in adult males that present conditions of deficiency or absence of endogenous testosterone. The approved conditions for the use of testosterone undecanoate are 1) primary hypogonadism, defined as a testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter's syndrome, chemotherapy or toxic damage from alcohol or heavy metals: or 2) hypogonadotropic hypogonadism caused by idiopathic gonadotropin or luteinizing hormone-releasing hormone deficiency or pituitary-hypothalamic injuries from tumors, trauma or radiation.[FDA label]
DB13952Estradiol acetateFemring is indicated for the treatment of vasomotor and urogenital symptoms associated with menopause. Use of Femring (estradiol acetate) has been shown to improve symptoms caused by atrophy of the vagina (such as dryness, burning, pruritus and dyspareunia) and/or the lower urinary tract (urinary urgency and dysuria).
DB13953Estradiol benzoateEstradiol benzoate is not currently available in any FDA or Health Canada approved products.
DB13954Estradiol cypionateDepo-Estradiol intramuscular depot injection is indicated for the treatment of moderate to severe vasomotor symptoms and hypoestrogenism due to hypogonadism.
DB13955Estradiol dienanthateEstradiol dienanthate is not currently available in any FDA or Health Canada approved products.
DB13956Estradiol valerateEstradiol valerate is commercially available as an intramuscular injection as the product Delestrogen and is indicated for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only). Estradiol valerate is also available in combination with [DB09123] as the commercially available product Natazia used for the prevention of pregnancy and for the treatment of heavy menstrual bleeding.
DB09231BenidipineBenidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris.[A31950]
DB11633Isavuconazole- Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. - Indicated for patients 18 years of age and older for the treatment of invasive mucormycosis [FDA Label], including patients where treatment amphotericin B is inappropriate [L1482].
DB11712TezacaftorTezacaftor, in combination with ivacaftor, is indicated for the treatment of cystic fibrosis in people aged 12 years or older who have two copies of the _F508del_ mutation or at least one mutation in the CFTR gene that is responsive to this treatment based on clinical evidence.[L1598] Cystic fibrosis is a rare, life-shortening disease caused by a defective or missing CFTR protein. This modification in the protein is caused by a mutation in the CFTR gene. The affected people carry two inherited defective copies of the CFTR gene. There are approximately 2000 known mutations in the CFTR gene. The presence of a defective or missing protein results in poor flow of salt and water into and out of the cell. This condition will cause the buildup of abnormally thick, sticky mucus in the lungs that will later potentially cause chronic lung infections and lung damage. In the patients with the _F508del_ mutation, the CFTR protein is not processed or folded normally within the cell and thus, it does not reach the cell surface.[L1599]
DB11586AsunaprevirAsunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis.[L2278] Hepatitis C is a liver disease caused by the hepatitis C virus. The chronic state of this condition accounts for 60-80% of the cases from which the risk of cirrhosis of the liver within 20 years is of around 15-30%.[L2281] The genotype 1 is the most common type of hepatitis C in the United States and the most difficult to treat.[L2282]
DB00820TadalafilUsed for the treatment of erectile dysfunction.
DB05521TelaprevirTelaprevir, when used in combination with [DB00811], [DB00008], and [DB00022] is indicated for use in the treatment of chronic HCV genotype 1 infection in adults [FDA Label].
DB14185Aripiprazole lauroxilAripiprazole lauroxil is indicated for the treatment of schizophrenia and related psychotic disorders.
DB09256TegafurIndicated for the treatment of cancer usually in combination with other biochemically modulating drugs. Indicated in adults for the treatment of advanced gastric cancer when given in combination with [DB00515] [L933]. Indicated for the first-line treatment of metastatic colorectal cancer with [DB03419] and calcium folinate [L934].
DB12301DoravirineDoravirine is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adult patients with no prior antiretroviral treatment history [FDA Label].
DB00564CarbamazepineFor the treatment of epilepsy and pain associated with true trigeminal neuralgia.
DB08899EnzalutamideEnzalutamide is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have previously received docetaxel.
DB00313Valproic AcidFor treatment and management of seizure disorders, mania, and prophylactic treatment of migraine headache. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome.
DB00738PentamidineFor the treatment of pneumonia due to Pneumocystis carinii.
DB12130LorlatinibLorlatinib is a third-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI) [L4848] indicated for the treatment of patients with ALK-positive metastatic non-small cell lung cancer (NSCLC) whose disease has progressed on a) the prior use of crizotinib and at least one other ALK inhibitor for metastatic disease, or b) the prior use of alectinib as the first ALK inhibitor therapy for metastatic disease, or c) the prior use of certinib as the first ALK inhibitor therapy for metastatic disease [L848, FDA Label].
DrugDrug NameTargetType
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C8enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineMultidrug resistance protein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineMultidrug resistance-associated protein 1transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB00224IndinavirCytochrome P450 3A4enzyme
DB00224IndinavirCytochrome P450 3A5enzyme
DB00224IndinavirCytochrome P450 3A7enzyme
DB00224IndinavirCytochrome P450 2D6enzyme
DB00224IndinavirUDP-glucuronosyltransferase 1-1enzyme
DB00224IndinavirHuman immunodeficiency virus type 1 proteasetarget
DB00224IndinavirMultidrug resistance protein 1transporter
DB00224IndinavirSolute carrier family 22 member 1transporter
DB00224IndinavirMultidrug resistance-associated protein 1transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1A2transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1B1transporter
DB00224IndinavirCanalicular multispecific organic anion transporter 1transporter
DB00224IndinavirSolute carrier organic anion transporter family member 2B1transporter
DB00224IndinavirBile salt export pumptransporter
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineMultidrug resistance protein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineTubulin beta chaintarget
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineMultidrug resistance protein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DB00661VerapamilCytochrome P450 1A2enzyme
DB00661VerapamilCytochrome P450 3A5enzyme
DB00661VerapamilCytochrome P450 3A4enzyme
DB00661VerapamilCytochrome P450 3A7enzyme
DB00661VerapamilCytochrome P450 2C8enzyme
DB00661VerapamilCytochrome P450 2C9enzyme
DB00661VerapamilCytochrome P450 2C18enzyme
DB00661VerapamilCytochrome P450 2B6enzyme
DB00661VerapamilCytochrome P450 2C19enzyme
DB00661VerapamilCytochrome P450 2D6enzyme
DB00661VerapamilSodium channel protein type 5 subunit alphatarget
DB00661VerapamilATP-sensitive inward rectifier potassium channel 11target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-4target
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-3target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-1target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-2target
DB00661VerapamilPotassium voltage-gated channel subfamily H member 2target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00661VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00661VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00661VerapamilSodium-dependent serotonin transportertarget
DB00661VerapamilAlpha-1A adrenergic receptortarget
DB00661VerapamilAlpha-1B adrenergic receptortarget
DB00661VerapamilAlpha-1D adrenergic receptortarget
DB00661VerapamilMultidrug resistance protein 1transporter
DB00661VerapamilSolute carrier family 22 member 1transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 2transporter
DB00661VerapamilMultidrug resistance-associated protein 4transporter
DB00661VerapamilSolute carrier family 22 member 5transporter
DB00661VerapamilMultidrug resistance-associated protein 1transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1A2transporter
DB00661VerapamilMultidrug resistance-associated protein 7transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 1transporter
DB00661VerapamilSolute carrier family 22 member 4transporter
DB00661VerapamilATP-binding cassette sub-family G member 2transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1B1transporter
DB00661VerapamilBile salt export pumptransporter
DB00683MidazolamCytochrome P450 3A4enzyme
DB00683MidazolamCytochrome P450 2B6enzyme
DB00683MidazolamCytochrome P450 3A5enzyme
DB00683MidazolamCytochrome P450 3A7enzyme
DB00683MidazolamCytochrome P450 4B1enzyme
DB00683MidazolamUDP-glucuronosyltransferase 1-4enzyme
DB00683MidazolamCytochrome P450 2E1enzyme
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-1target
DB00683MidazolamGamma-aminobutyric acid receptor subunit beta-1target
DB00683MidazolamGamma-aminobutyric acid receptor subunit beta-3target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-5target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-3target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-2target
DB00683MidazolamGamma-aminobutyric acid receptor subunit beta-2target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-4target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-6target
DB00683MidazolamGamma-aminobutyric acid receptor subunit gamma-1target
DB00683MidazolamGamma-aminobutyric acid receptor subunit gamma-2target
DB00683MidazolamGamma-aminobutyric acid receptor subunit gamma-3target
DB00683MidazolamGamma-aminobutyric acid receptor subunit deltatarget
DB00683MidazolamGamma-aminobutyric acid receptor subunit epsilontarget
DB00683MidazolamGamma-aminobutyric acid receptor subunit pitarget
DB00683MidazolamGamma-aminobutyric acid receptor subunit rho-1target
DB00683MidazolamGamma-aminobutyric acid receptor subunit rho-2target
DB00683MidazolamGamma-aminobutyric acid receptor subunit thetatarget
DB00683MidazolamGamma-aminobutyric acid receptor subunit rho-3target
DB00683MidazolamMultidrug resistance protein 1transporter
DB00683MidazolamBile salt export pumptransporter
DB00864TacrolimusSerum albumincarrier
DB00864TacrolimusAlpha-1-acid glycoprotein 1carrier
DB00864TacrolimusCytochrome P450 3A4enzyme
DB00864TacrolimusCytochrome P450 3A5enzyme
DB00864TacrolimusCytochrome P450 3A7enzyme
DB00864TacrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00864TacrolimusMultidrug resistance protein 1transporter
DB00864TacrolimusATP-binding cassette sub-family A member 5transporter
DB00864TacrolimusSolute carrier organic anion transporter family member 1B1transporter
DB01232SaquinavirAlpha-1-acid glycoprotein 1carrier
DB01232SaquinavirSerum albumincarrier
DB01232SaquinavirCytochrome P450 3A4enzyme
DB01232SaquinavirCytochrome P450 3A5enzyme
DB01232SaquinavirCytochrome P450 3A7enzyme
DB01232SaquinavirCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01232SaquinavirCytochrome P450 2C8enzyme
DB01232SaquinavirCytochrome P450 2D6enzyme
DB01232SaquinavirHuman immunodeficiency virus type 1 proteasetarget
DB01232SaquinavirMultidrug resistance protein 1transporter
DB01232SaquinavirSolute carrier family 22 member 1transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1A2transporter
DB01232SaquinavirATP-binding cassette sub-family G member 2transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1B1transporter
DB01232SaquinavirMultidrug resistance-associated protein 1transporter
DB01232SaquinavirCanalicular multispecific organic anion transporter 1transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 2B1transporter
DB01232SaquinavirBile salt export pumptransporter
DB00802AlfentanilAlpha-1-acid glycoprotein 1carrier
DB00802AlfentanilSerum albumincarrier
DB00802AlfentanilCytochrome P450 3A4enzyme
DB00802AlfentanilCytochrome P450 3A5enzyme
DB00802AlfentanilCytochrome P450 3A7enzyme
DB00802AlfentanilMu-type opioid receptortarget
DB00802AlfentanilMultidrug resistance protein 1transporter
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 1A1enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilMultidrug resistance protein 1transporter
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibBCR/ABL fusion protein isoform X9target
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibMultidrug resistance protein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibBile salt export pumptransporter
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DB00675TamoxifenMultidrug resistance protein 1transporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675TamoxifenBile salt export pumptransporter
DB00238NevirapineSerum albumincarrier
DB00238NevirapineCytochrome P450 3A4enzyme
DB00238NevirapineCytochrome P450 2B6enzyme
DB00238NevirapineCytochrome P450 3A5enzyme
DB00238NevirapineCytochrome P450 2C9enzyme
DB00238NevirapineCytochrome P450 2A6enzyme
DB00238NevirapineCytochrome P450 2D6enzyme
DB00238NevirapineCytochrome P450 1A2enzyme
DB00238NevirapineReverse transcriptase/RNaseHtarget
DB00238NevirapineSolute carrier family 22 member 1transporter
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 2C19enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinCytochrome P450 3A7enzyme
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01211ClarithromycinMultidrug resistance protein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinBile salt export pumptransporter
DB00976TelithromycinCytochrome P450 3A4enzyme
DB00976TelithromycinCytochrome P450 3A5enzyme
DB00976TelithromycinCytochrome P450 3A7enzyme
DB00976Telithromycin23S rRNAtarget
DB00976TelithromycinSolute carrier organic anion transporter family member 1B1transporter
DB00976TelithromycinSolute carrier organic anion transporter family member 1B3transporter
DB00404AlprazolamCytochrome P450 3A4enzyme
DB00404AlprazolamCytochrome P450 2C9enzyme
DB00404AlprazolamCytochrome P450 3A5enzyme
DB00404AlprazolamCytochrome P450 3A7enzyme
DB00404AlprazolamGABA-A receptor (anion channel)target
DB00829DiazepamSerum albumincarrier
DB00829DiazepamCytochrome P450 3A4enzyme
DB00829DiazepamCytochrome P450 2C9enzyme
DB00829DiazepamCytochrome P450 2C19enzyme
DB00829DiazepamCytochrome P450 3A5enzyme
DB00829DiazepamCytochrome P450 3A7enzyme
DB00829DiazepamCytochrome P450 2B6enzyme
DB00829DiazepamProstaglandin G/H synthase 1enzyme
DB00829DiazepamCytochrome P450 2C18enzyme
DB00829DiazepamCytochrome P450 2C8enzyme
DB00829DiazepamCytochrome P450 2E1enzyme
DB00829DiazepamTranslocator proteintarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit pitarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00829DiazepamGABA-A receptor (anion channel)target
DB00829DiazepamMultidrug resistance protein 1transporter
DB00897TriazolamCytochrome P450 3A4enzyme
DB00897TriazolamCytochrome P450 3A5enzyme
DB00897TriazolamCytochrome P450 3A7enzyme
DB00897TriazolamCytochrome P450 2C8enzyme
DB00897TriazolamTranslocator proteintarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-4target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-5target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-6target
DB00897TriazolamGamma-aminobutyric acid receptor subunit beta-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit beta-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit beta-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit gamma-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit gamma-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit gamma-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit deltatarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit epsilontarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit pitarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit rho-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit rho-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit rho-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit thetatarget
DB00897TriazolamGABA-A receptor (anion channel)target
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00637AstemizoleCytochrome P450 3A4enzyme
DB00637AstemizoleCytochrome P450 3A5enzyme
DB00637AstemizoleCytochrome P450 3A7enzyme
DB00637AstemizoleCytochrome P450 2D6enzyme
DB00637AstemizoleCytochrome P450 2J2enzyme
DB00637AstemizoleHistamine H1 receptortarget
DB00637AstemizolePotassium voltage-gated channel subfamily H member 2target
DB00637AstemizolePotassium voltage-gated channel subfamily H member 1target
DB00637AstemizoleMicrotubule-associated protein tautarget
DB00637AstemizoleMultidrug resistance protein 1transporter
DB00637AstemizoleBile salt export pumptransporter
DB01114ChlorphenamineCytochrome P450 3A4enzyme
DB01114ChlorphenamineCytochrome P450 2D6enzyme
DB01114ChlorphenamineCytochrome P450 3A5enzyme
DB01114ChlorphenamineCytochrome P450 3A7enzyme
DB01114ChlorphenamineHistamine H1 receptortarget
DB01114ChlorphenamineSodium-dependent serotonin transportertarget
DB01114ChlorphenamineSodium-dependent noradrenaline transportertarget
DB01114ChlorphenamineSodium-dependent dopamine transportertarget
DB01114ChlorphenamineSolute carrier family 22 member 2transporter
DB01114ChlorphenamineSolute carrier family 22 member 1transporter
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineCytochrome P450 3A7enzyme
DB00381AmlodipineCytochrome P450 2A6enzyme
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2C9enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00381AmlodipineVoltage-gated calcium channel beta 1 subunit splice variant CavB1dtarget
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB00381AmlodipineMultidrug resistance protein 1transporter
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemMultidrug resistance protein 1transporter
DB01023FelodipineCytochrome P450 3A4enzyme
DB01023FelodipineCytochrome P450 2C8enzyme
DB01023FelodipineCytochrome P450 3A5enzyme
DB01023FelodipineCytochrome P450 3A7enzyme
DB01023FelodipineCytochrome P450 2C9enzyme
DB01023FelodipineCytochrome P450 2D6enzyme
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01023FelodipineCalmodulintarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB01023FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB01023FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01023FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01023FelodipineTroponin C, skeletal muscletarget
DB01023FelodipineTroponin C, slow skeletal and cardiac musclestarget
DB01023FelodipineMineralocorticoid receptortarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01023FelodipineMultidrug resistance protein 1transporter
DB01023FelodipineBile salt export pumptransporter
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCytochrome P450 3A5enzyme
DB01115NifedipineCytochrome P450 3A7enzyme
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily A member 1target
DB01115NifedipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineMultidrug resistance protein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB00401NisoldipineCytochrome P450 3A4enzyme
DB00401NisoldipineCytochrome P450 3A5enzyme
DB00401NisoldipineCytochrome P450 3A7enzyme
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00401NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00401NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00401NisoldipineMultidrug resistance protein 1transporter
DB01054NitrendipineCytochrome P450 3A4enzyme
DB01054NitrendipineCytochrome P450 3A5enzyme
DB01054NitrendipineCytochrome P450 3A7enzyme
DB01054NitrendipineVoltage-dependent calcium channel gamma-1 subunittarget
DB01054NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01054NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01054NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01054NitrendipineMultidrug resistance protein 1transporter
DB01054NitrendipineBile salt export pumptransporter
DB01076AtorvastatinCytochrome P450 3A4enzyme
DB01076AtorvastatinCytochrome P450 2D6enzyme
DB01076AtorvastatinCytochrome P450 2C9enzyme
DB01076AtorvastatinCytochrome P450 2C19enzyme
DB01076AtorvastatinCytochrome P450 3A5enzyme
DB01076AtorvastatinCytochrome P450 3A7enzyme
DB01076AtorvastatinCytochrome P450 2B6enzyme
DB01076AtorvastatinCytochrome P450 2C8enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01076Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01076AtorvastatinDipeptidyl peptidase 4target
DB01076AtorvastatinAryl hydrocarbon receptortarget
DB01076AtorvastatinMultidrug resistance protein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01076AtorvastatinMultidrug resistance-associated protein 4transporter
DB01076AtorvastatinMultidrug resistance-associated protein 5transporter
DB01076AtorvastatinMultidrug resistance-associated protein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01076AtorvastatinCanalicular multispecific organic anion transporter 1transporter
DB01076AtorvastatinBile salt export pumptransporter
DB00227LovastatinCytochrome P450 3A4enzyme
DB00227LovastatinCytochrome P450 2C8enzyme
DB00227LovastatinSerum paraoxonase/lactonase 3enzyme
DB00227LovastatinCytochrome P450 2C9enzyme
DB00227LovastatinCytochrome P450 3A5enzyme
DB00227LovastatinCytochrome P450 3A7enzyme
DB00227LovastatinCytochrome P450 2D6enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-1enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-3enzyme
DB00227LovastatinUDP-glucuronosyltransferase 2B7enzyme
DB00227Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00227LovastatinIntegrin alpha-Ltarget
DB00227LovastatinHistone deacetylase 2target
DB00227LovastatinMultidrug resistance protein 1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1A2transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B1transporter
DB00227LovastatinCanalicular multispecific organic anion transporter 1transporter
DB00227LovastatinBile salt export pumptransporter
DB00641SimvastatinCytochrome P450 3A4enzyme
DB00641SimvastatinCytochrome P450 2C8enzyme
DB00641SimvastatinCytochrome P450 2C9enzyme
DB00641SimvastatinCytochrome P450 2C19enzyme
DB00641SimvastatinCytochrome P450 3A5enzyme
DB00641SimvastatinCytochrome P450 3A7enzyme
DB00641SimvastatinCytochrome P450 2B6enzyme
DB00641SimvastatinCytochrome P450 2D6enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-1enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-3enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 2B7enzyme
DB00641Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00641SimvastatinIntegrin beta-2target
DB00641SimvastatinIntegrin alpha-Ltarget
DB00641SimvastatinMultidrug resistance protein 1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1A2transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B1transporter
DB00641SimvastatinCanalicular multispecific organic anion transporter 1transporter
DB00641SimvastatinBile salt export pumptransporter
DB01238AripiprazoleCytochrome P450 3A4enzyme
DB01238AripiprazoleCytochrome P450 2D6enzyme
DB01238AripiprazoleCytochrome P450 3A5enzyme
DB01238AripiprazoleCytochrome P450 3A7enzyme
DB01238AripiprazoleD(2) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Btarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Dtarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Etarget
DB01238AripiprazoleD(1A) dopamine receptortarget
DB01238AripiprazoleD(1B) dopamine receptortarget
DB01238AripiprazoleD(3) dopamine receptortarget
DB01238AripiprazoleD(4) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Ctarget
DB01238Aripiprazole5-hydroxytryptamine receptor 3Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 6target
DB01238Aripiprazole5-hydroxytryptamine receptor 7target
DB01238AripiprazoleHistamine H1 receptortarget
DB01238AripiprazoleAlpha-1A adrenergic receptortarget
DB01238AripiprazoleAlpha-1B adrenergic receptortarget
DB01238AripiprazoleAlpha-2A adrenergic receptortarget
DB01238AripiprazoleAlpha-2B adrenergic receptortarget
DB01238AripiprazoleAlpha-2C adrenergic receptortarget
DB01238AripiprazoleMuscarinic acetylcholine receptor M1target
DB01238AripiprazoleMuscarinic acetylcholine receptor M2target
DB01238AripiprazoleMuscarinic acetylcholine receptor M3target
DB01238AripiprazoleMuscarinic acetylcholine receptor M4target
DB01238AripiprazoleMuscarinic acetylcholine receptor M5target
DB00490BuspironeCytochrome P450 3A4enzyme
DB00490BuspironeCytochrome P450 3A5enzyme
DB00490BuspironeCytochrome P450 3A7enzyme
DB00490BuspironeCytochrome P450 2D6enzyme
DB00490Buspirone5-hydroxytryptamine receptor 1Atarget
DB00490BuspironeD(2) dopamine receptortarget
DB00490BuspironeMultidrug resistance protein 1transporter
DB00502HaloperidolCytochrome P450 1A2enzyme
DB00502HaloperidolCytochrome P450 2D6enzyme
DB00502HaloperidolCytochrome P450 3A4enzyme
DB00502HaloperidolCytochrome P450 3A5enzyme
DB00502HaloperidolCytochrome P450 3A7enzyme
DB00502HaloperidolCarbonyl reductase [NADPH] 1enzyme
DB00502HaloperidolUDP-glucuronosyltransferase 1-9enzyme
DB00502HaloperidolCytochrome P450 1A1enzyme
DB00502HaloperidolCytochrome P450 2C19enzyme
DB00502HaloperidolCytochrome P450 2C9enzyme
DB00502HaloperidolD(2) dopamine receptortarget
DB00502HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
DB00502HaloperidolD(1A) dopamine receptortarget
DB00502Haloperidol5-hydroxytryptamine receptor 2Atarget
DB00502HaloperidolD(3) dopamine receptortarget
DB00502HaloperidolMelanin-concentrating hormone receptor 1target
DB00502HaloperidolSynaptic vesicular amine transportertarget
DB00502HaloperidolMultidrug resistance protein 1transporter
DB01100PimozideCytochrome P450 3A4enzyme
DB01100PimozideCytochrome P450 1A2enzyme
DB01100PimozideCytochrome P450 3A5enzyme
DB01100PimozideCytochrome P450 3A7enzyme
DB01100PimozideCytochrome P450 2D6enzyme
DB01100PimozideCytochrome P450 2E1enzyme
DB01100PimozideD(2) dopamine receptortarget
DB01100PimozideCalmodulintarget
DB01100PimozidePotassium voltage-gated channel subfamily H member 2target
DB01100PimozideD(3) dopamine receptortarget
DB01100PimozideMultidrug resistance protein 1transporter
DB00877SirolimusCytochrome P450 3A4enzyme
DB00877SirolimusCytochrome P450 3A5enzyme
DB00877SirolimusCytochrome P450 3A7enzyme
DB00877SirolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00877SirolimusSerine/threonine-protein kinase mTORtarget
DB00877SirolimusFibroblast growth factor 2target
DB00877SirolimusMultidrug resistance protein 1transporter
DB00877SirolimusSolute carrier organic anion transporter family member 1B1transporter
DB00877SirolimusMultidrug and toxin extrusion protein 1transporter
DB00656TrazodoneAlpha-1-acid glycoprotein 1carrier
DB00656TrazodoneCytochrome P450 2D6enzyme
DB00656TrazodoneCytochrome P450 3A4enzyme
DB00656TrazodoneCytochrome P450 3A5enzyme
DB00656TrazodoneCytochrome P450 3A7enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Atarget
DB00656TrazodoneSodium-dependent serotonin transportertarget
DB00656TrazodoneAlpha-1A adrenergic receptortarget
DB00656TrazodoneAlpha-2A adrenergic receptortarget
DB00656TrazodoneHistamine H1 receptortarget
DB00656Trazodone5-hydroxytryptamine receptor 1Atarget
DB00656Trazodone5-hydroxytryptamine receptor 2Ctarget
DB00656TrazodoneMultidrug resistance protein 1transporter
DB00175PravastatinCytochrome P450 2C8enzyme
DB00175Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00175PravastatinSolute carrier organic anion transporter family member 2B1transporter
DB00175PravastatinMultidrug resistance protein 1transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1A2transporter
DB00175PravastatinSolute carrier family 22 member 6transporter
DB00175PravastatinSolute carrier family 22 member 8transporter
DB00175PravastatinCanalicular multispecific organic anion transporter 1transporter
DB00175PravastatinSolute carrier family 22 member 11transporter
DB00175PravastatinATP-binding cassette sub-family G member 2transporter
DB00175PravastatinSolute carrier family 22 member 7transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B1transporter
DB00175PravastatinMonocarboxylate transporter 1transporter
DB00175PravastatinBile salt export pumptransporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B3transporter
DB00862VardenafilCytochrome P450 3A4enzyme
DB00862VardenafilCytochrome P450 3A5enzyme
DB00862VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00862VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilMultidrug resistance protein 1transporter
DB08873BoceprevirCytochrome P450 3A4enzyme
DB08873BoceprevirCytochrome P450 3A5enzyme
DB08873BoceprevirNS3/4A proteintarget
DB08873BoceprevirMultidrug resistance protein 1transporter
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirMultidrug resistance protein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB06267UdenafilCytochrome P450 3A4enzyme
DB06267UdenafilCytochrome P450 3A5enzyme
DB06267UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB00741Hydrocortisone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB00741HydrocortisoneMultidrug resistance protein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneATP-binding cassette sub-family G member 2transporter
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB14538Hydrocortisone aceponateSex hormone-binding globulincarrier
DB14538Hydrocortisone aceponateCorticosteroid-binding globulincarrier
DB14538Hydrocortisone aceponateCytochrome P450 3A4enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A5enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A7enzyme
DB14538Hydrocortisone aceponateCytochrome P450 11B1, mitochondrialenzyme
DB14538Hydrocortisone aceponateCytochrome P450 11B2, mitochondrialenzyme
DB14538Hydrocortisone aceponateCytochrome P450 2C8enzyme
DB14538Hydrocortisone aceponateAnnexin A1target
DB14538Hydrocortisone aceponateGlucocorticoid receptortarget
DB14538Hydrocortisone aceponateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14538Hydrocortisone aceponate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14538Hydrocortisone aceponateMultidrug resistance protein 1transporter
DB14538Hydrocortisone aceponateSolute carrier organic anion transporter family member 1A2transporter
DB14538Hydrocortisone aceponateATP-binding cassette sub-family G member 2transporter
DB14538Hydrocortisone aceponateSolute carrier family 22 member 8transporter
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateMultidrug resistance protein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB14540Hydrocortisone butyrateSex hormone-binding globulincarrier
DB14540Hydrocortisone butyrateCorticosteroid-binding globulincarrier
DB14540Hydrocortisone butyrateCytochrome P450 3A4enzyme
DB14540Hydrocortisone butyrateCytochrome P450 3A5enzyme
DB14540Hydrocortisone butyrateCytochrome P450 3A7enzyme
DB14540Hydrocortisone butyrateCytochrome P450 11B1, mitochondrialenzyme
DB14540Hydrocortisone butyrateCytochrome P450 11B2, mitochondrialenzyme
DB14540Hydrocortisone butyrateCytochrome P450 2C8enzyme
DB14540Hydrocortisone butyrateAnnexin A1target
DB14540Hydrocortisone butyrateGlucocorticoid receptortarget
DB14540Hydrocortisone butyrateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14540Hydrocortisone butyrate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14540Hydrocortisone butyrateMultidrug resistance protein 1transporter
DB14540Hydrocortisone butyrateSolute carrier organic anion transporter family member 1A2transporter
DB14540Hydrocortisone butyrateATP-binding cassette sub-family G member 2transporter
DB14540Hydrocortisone butyrateSolute carrier family 22 member 8transporter
DB14541Hydrocortisone cypionateSex hormone-binding globulincarrier
DB14541Hydrocortisone cypionateCorticosteroid-binding globulincarrier
DB14541Hydrocortisone cypionateCytochrome P450 3A4enzyme
DB14541Hydrocortisone cypionateCytochrome P450 3A5enzyme
DB14541Hydrocortisone cypionateCytochrome P450 3A7enzyme
DB14541Hydrocortisone cypionateCytochrome P450 11B1, mitochondrialenzyme
DB14541Hydrocortisone cypionateCytochrome P450 11B2, mitochondrialenzyme
DB14541Hydrocortisone cypionateCytochrome P450 2C8enzyme
DB14541Hydrocortisone cypionateAnnexin A1target
DB14541Hydrocortisone cypionateGlucocorticoid receptortarget
DB14541Hydrocortisone cypionateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14541Hydrocortisone cypionate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14541Hydrocortisone cypionateMultidrug resistance protein 1transporter
DB14541Hydrocortisone cypionateSolute carrier organic anion transporter family member 1A2transporter
DB14541Hydrocortisone cypionateATP-binding cassette sub-family G member 2transporter
DB14541Hydrocortisone cypionateSolute carrier family 22 member 8transporter
DB14542Hydrocortisone phosphateSex hormone-binding globulincarrier
DB14542Hydrocortisone phosphateCorticosteroid-binding globulincarrier
DB14542Hydrocortisone phosphateCytochrome P450 3A4enzyme
DB14542Hydrocortisone phosphateCytochrome P450 3A5enzyme
DB14542Hydrocortisone phosphateCytochrome P450 3A7enzyme
DB14542Hydrocortisone phosphateCytochrome P450 11B1, mitochondrialenzyme
DB14542Hydrocortisone phosphateCytochrome P450 11B2, mitochondrialenzyme
DB14542Hydrocortisone phosphateCytochrome P450 2C8enzyme
DB14542Hydrocortisone phosphateAnnexin A1target
DB14542Hydrocortisone phosphateGlucocorticoid receptortarget
DB14542Hydrocortisone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14542Hydrocortisone phosphate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14542Hydrocortisone phosphateMultidrug resistance protein 1transporter
DB14542Hydrocortisone phosphateSolute carrier organic anion transporter family member 1A2transporter
DB14542Hydrocortisone phosphateATP-binding cassette sub-family G member 2transporter
DB14542Hydrocortisone phosphateSolute carrier family 22 member 8transporter
DB14543Hydrocortisone probutateSex hormone-binding globulincarrier
DB14543Hydrocortisone probutateCorticosteroid-binding globulincarrier
DB14543Hydrocortisone probutateCytochrome P450 3A4enzyme
DB14543Hydrocortisone probutateCytochrome P450 3A5enzyme
DB14543Hydrocortisone probutateCytochrome P450 3A7enzyme
DB14543Hydrocortisone probutateCytochrome P450 11B1, mitochondrialenzyme
DB14543Hydrocortisone probutateCytochrome P450 11B2, mitochondrialenzyme
DB14543Hydrocortisone probutateCytochrome P450 2C8enzyme
DB14543Hydrocortisone probutateAnnexin A1target
DB14543Hydrocortisone probutateGlucocorticoid receptortarget
DB14543Hydrocortisone probutateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14543Hydrocortisone probutate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14543Hydrocortisone probutateMultidrug resistance protein 1transporter
DB14543Hydrocortisone probutateSolute carrier organic anion transporter family member 1A2transporter
DB14543Hydrocortisone probutateATP-binding cassette sub-family G member 2transporter
DB14543Hydrocortisone probutateSolute carrier family 22 member 8transporter
DB14545Hydrocortisone succinateCytochrome P450 3A4enzyme
DB14545Hydrocortisone succinateCytochrome P450 3A5enzyme
DB14545Hydrocortisone succinateCytochrome P450 3A7enzyme
DB14545Hydrocortisone succinateCytochrome P450 2C8enzyme
DB14545Hydrocortisone succinateCytochrome P450 11B1, mitochondrialenzyme
DB14545Hydrocortisone succinateCytochrome P450 11B2, mitochondrialenzyme
DB14544Hydrocortisone valerateSex hormone-binding globulincarrier
DB14544Hydrocortisone valerateCorticosteroid-binding globulincarrier
DB14544Hydrocortisone valerateCytochrome P450 3A4enzyme
DB14544Hydrocortisone valerateCytochrome P450 3A5enzyme
DB14544Hydrocortisone valerateCytochrome P450 3A7enzyme
DB14544Hydrocortisone valerateCytochrome P450 11B1, mitochondrialenzyme
DB14544Hydrocortisone valerateCytochrome P450 11B2, mitochondrialenzyme
DB14544Hydrocortisone valerateCytochrome P450 2C8enzyme
DB14544Hydrocortisone valerateAnnexin A1target
DB14544Hydrocortisone valerateGlucocorticoid receptortarget
DB14544Hydrocortisone valerateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14544Hydrocortisone valerate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14544Hydrocortisone valerateMultidrug resistance protein 1transporter
DB14544Hydrocortisone valerateSolute carrier organic anion transporter family member 1A2transporter
DB14544Hydrocortisone valerateATP-binding cassette sub-family G member 2transporter
DB14544Hydrocortisone valerateSolute carrier family 22 member 8transporter
DB06789Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
DB06789Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
DB06789Hydroxyprogesterone caproateCytochrome P450 2C19enzyme
DB06789Hydroxyprogesterone caproateProgesterone receptortarget
DB00717NorethisteroneSerum albumincarrier
DB00717NorethisteroneSex hormone-binding globulincarrier
DB00717NorethisteroneCytochrome P450 3A4enzyme
DB00717NorethisteroneCytochrome P450 2C19enzyme
DB00717NorethisteroneCytochrome P450 3A5enzyme
DB00717NorethisteroneCytochrome P450 3A7enzyme
DB00717NorethisteroneProgesterone receptortarget
DB00717NorethisteroneMultidrug resistance protein 1transporter
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2C8enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneNuclear receptor subfamily 1 group I member 2target
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneMultidrug resistance protein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB09068VortioxetineCytochrome P450 2D6enzyme
DB09068VortioxetineCytochrome P450 3A4enzyme
DB09068VortioxetineCytochrome P450 3A5enzyme
DB09068VortioxetineCytochrome P450 2C19enzyme
DB09068VortioxetineCytochrome P450 2C9enzyme
DB09068VortioxetineCytochrome P450 2A6enzyme
DB09068VortioxetineCytochrome P450 2C8enzyme
DB09068VortioxetineCytochrome P450 2B6enzyme
DB09068VortioxetineSodium-dependent serotonin transportertarget
DB09068Vortioxetine5-hydroxytryptamine receptor 3Atarget
DB09068Vortioxetine5-hydroxytryptamine receptor 7target
DB09068Vortioxetine5-hydroxytryptamine receptor 1Btarget
DB09068Vortioxetine5-hydroxytryptamine receptor 1Atarget
DB09068VortioxetineBeta-1 adrenergic receptortarget
DB09068Vortioxetinesolute carrier family 6 member 2target
DB08883PerampanelCytochrome P450 3A4enzyme
DB08883PerampanelCytochrome P450 3A5enzyme
DB08883PerampanelCytochrome P450 1A2enzyme
DB08883PerampanelCytochrome P450 2B6enzyme
DB08883PerampanelGlutamate receptor 1target
DB08865CrizotinibCytochrome P450 3A4enzyme
DB08865CrizotinibCytochrome P450 3A5enzyme
DB08865CrizotinibCytochrome P450 2B6enzyme
DB08865CrizotinibCYP3Aenzyme
DB08865CrizotinibALK tyrosine kinase receptortarget
DB08865CrizotinibHepatocyte growth factor receptortarget
DB08865CrizotinibMultidrug resistance protein 1transporter
DB06626AxitinibCytochrome P450 3A4enzyme
DB06626AxitinibCytochrome P450 3A5enzyme
DB06626AxitinibCytochrome P450 1A2enzyme
DB06626AxitinibCytochrome P450 2C19enzyme
DB06626AxitinibUDP-glucuronosyltransferase 1-1enzyme
DB06626AxitinibVascular endothelial growth factor receptor 1target
DB06626AxitinibVascular endothelial growth factor receptor 2target
DB06626AxitinibVascular endothelial growth factor receptor 3target
DB06626AxitinibMultidrug resistance protein 1transporter
DB06626AxitinibSolute carrier organic anion transporter family member 1B1transporter
DB01267PaliperidoneCytochrome P450 3A4enzyme
DB01267PaliperidoneCytochrome P450 2D6enzyme
DB01267PaliperidoneCytochrome P450 3A5enzyme
DB01267PaliperidoneD(2) dopamine receptortarget
DB01267Paliperidone5-hydroxytryptamine receptor 2Atarget
DB01267PaliperidoneHistamine H1 receptortarget
DB01267PaliperidoneAlpha-1A adrenergic receptortarget
DB01267PaliperidoneAlpha-1B adrenergic receptortarget
DB01267PaliperidoneD(3) dopamine receptortarget
DB01267PaliperidoneD(4) dopamine receptortarget
DB01267PaliperidoneD(1A) dopamine receptortarget
DB01267PaliperidoneAlpha-2A adrenergic receptortarget
DB01267PaliperidoneAlpha-2B adrenergic receptortarget
DB01267PaliperidoneAlpha-2C adrenergic receptortarget
DB01267Paliperidone5-hydroxytryptamine receptor 1Atarget
DB01267Paliperidone5-hydroxytryptamine receptor 1Dtarget
DB01267Paliperidone5-hydroxytryptamine receptor 2Ctarget
DB01267Paliperidone5-hydroxytryptamine receptor 7target
DB01267PaliperidoneMultidrug resistance protein 1transporter
DB01259LapatinibCytochrome P450 3A4enzyme
DB01259LapatinibCytochrome P450 2C8enzyme
DB01259LapatinibCytochrome P450 3A5enzyme
DB01259LapatinibCytochrome P450 2C19enzyme
DB01259LapatinibEpidermal growth factor receptortarget
DB01259LapatinibReceptor tyrosine-protein kinase erbB-2target
DB01259LapatinibMultidrug resistance protein 1transporter
DB01259LapatinibAntigen peptide transporter 1transporter
DB11737IcotinibCytochrome P450 3A4enzyme
DB11737IcotinibCytochrome P450 1A2enzyme
DB11737IcotinibCytochrome P450 3A5enzyme
DB11737IcotinibEpidermal growth factor receptortarget
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00472FluoxetineMultidrug resistance protein 1transporter
DB00734RisperidoneCytochrome P450 2D6enzyme
DB00734RisperidoneCytochrome P450 3A4enzyme
DB00734RisperidoneCytochrome P450 3A5enzyme
DB00734RisperidoneCytochrome P450 3A7enzyme
DB00734RisperidoneHistamine H1 receptortarget
DB00734RisperidoneD(2) dopamine receptortarget
DB00734RisperidoneAlpha-1A adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 2Atarget
DB00734RisperidoneAlpha-1B adrenergic receptortarget
DB00734RisperidoneD(1A) dopamine receptortarget
DB00734RisperidoneAlpha-2A adrenergic receptortarget
DB00734RisperidoneAlpha-2B adrenergic receptortarget
DB00734RisperidoneAlpha-2C adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 1Atarget
DB00734Risperidone5-hydroxytryptamine receptor 1Dtarget
DB00734Risperidone5-hydroxytryptamine receptor 2Ctarget
DB00734RisperidoneD(3) dopamine receptortarget
DB00734RisperidoneD(4) dopamine receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 7target
DB09297ParitaprevirCytochrome P450 3A4enzyme
DB09297ParitaprevirCytochrome P450 3A5enzyme
DB09297ParitaprevirNS3/4A proteintarget
DB09297ParitaprevirATP-binding cassette sub-family G member 2transporter
DB09297ParitaprevirMultidrug resistance protein 1transporter
DB09297ParitaprevirSolute carrier organic anion transporter family member 1B1transporter
DB09297ParitaprevirSolute carrier organic anion transporter family member 1B3transporter
DB00813FentanylCytochrome P450 3A4enzyme
DB00813FentanylCytochrome P450 3A5enzyme
DB00813FentanylCytochrome P450 3A7enzyme
DB00813FentanylMu-type opioid receptortarget
DB00813FentanylDelta-type opioid receptortarget
DB00813FentanylKappa-type opioid receptortarget
DB00813FentanylMultidrug resistance protein 1target
DB00813FentanylMultidrug resistance protein 1transporter
DB06287TemsirolimusCytochrome P450 3A4enzyme
DB06287TemsirolimusCytochrome P450 3A5enzyme
DB06287TemsirolimusCytochrome P450 3A7enzyme
DB06287TemsirolimusCytochrome P450 2D6enzyme
DB06287TemsirolimusSerine/threonine-protein kinase mTORtarget
DB06287TemsirolimusMultidrug resistance protein 1transporter
DB01098RosuvastatinSerum albumincarrier
DB01098RosuvastatinCytochrome P450 2C9enzyme
DB01098RosuvastatinCytochrome P450 2C19enzyme
DB01098RosuvastatinCytochrome P450 3A4enzyme
DB01098RosuvastatinCytochrome P450 3A5enzyme
DB01098Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01098RosuvastatinMultidrug resistance-associated protein 4transporter
DB01098RosuvastatinMultidrug resistance-associated protein 1transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01098RosuvastatinCystine/glutamate transportertransporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01098RosuvastatinBile salt export pumptransporter
DB01098RosuvastatinATP-binding cassette sub-family G member 2transporter
DB01098RosuvastatinCanalicular multispecific organic anion transporter 1transporter
DB01098RosuvastatinSolute carrier family 22 member 8transporter
DB00393NimodipineCytochrome P450 3A4enzyme
DB00393NimodipineCytochrome P450 3A5enzyme
DB00393NimodipineMineralocorticoid receptortarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
DB00393NimodipineAryl hydrocarbon receptortarget
DB00909ZonisamideCytochrome P450 3A4enzyme
DB00909ZonisamideAldehyde oxidaseenzyme
DB00909ZonisamideCytochrome P450 2C19enzyme
DB00909ZonisamideUDP-glucuronosyltransferase 1-1enzyme
DB00909ZonisamideCytochrome P450 3A5enzyme
DB00909ZonisamideSodium channel protein type 1 subunit alphatarget
DB00909ZonisamideCarbonic anhydrase 1target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00909ZonisamideAmine oxidase [flavin-containing] Btarget
DB00909ZonisamideCarbonic anhydrase 2target
DB00909ZonisamideCarbonic anhydrase 3target
DB00909ZonisamideCarbonic anhydrase 4target
DB00909ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 6target
DB00909ZonisamideCarbonic anhydrase 7target
DB00909ZonisamideCarbonic anhydrase-related proteintarget
DB00909ZonisamideCarbonic anhydrase 9target
DB00909ZonisamideCarbonic anhydrase-related protein 10target
DB00909ZonisamideCarbonic anhydrase-related protein 11target
DB00909ZonisamideCarbonic anhydrase 12target
DB00909ZonisamideCarbonic anhydrase 13target
DB00909ZonisamideCarbonic anhydrase 14target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00909ZonisamideSodium channel protein type 2 subunit alphatarget
DB00909ZonisamideSodium channel protein type 3 subunit alphatarget
DB00909ZonisamideSodium channel protein type 4 subunit alphatarget
DB00909ZonisamideSodium channel protein type 5 subunit alphatarget
DB00909ZonisamideSodium channel protein type 9 subunit alphatarget
DB00909ZonisamideSodium channel protein type 11 subunit alphatarget
DB00909ZonisamideSodium channel subunit beta-1target
DB00909ZonisamideSodium channel subunit beta-2target
DB00909ZonisamideSodium channel subunit beta-3target
DB00909ZonisamideSodium channel subunit beta-4target
DB00909ZonisamideAmine oxidase [flavin-containing] Atarget
DB01095FluvastatinCytochrome P450 2C9enzyme
DB01095FluvastatinCytochrome P450 3A4enzyme
DB01095FluvastatinCytochrome P450 2C8enzyme
DB01095FluvastatinCytochrome P450 2D6enzyme
DB01095FluvastatinCytochrome P450 2C19enzyme
DB01095FluvastatinCytochrome P450 1A1enzyme
DB01095FluvastatinCytochrome P450 3A5enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01095FluvastatinCytochrome P450 2B6enzyme
DB01095Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01095FluvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01095FluvastatinSolute carrier family 15 member 1transporter
DB01095FluvastatinCanalicular multispecific organic anion transporter 1transporter
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelMultidrug resistance protein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanMultidrug resistance protein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DB00834MifepristoneCytochrome P450 3A4enzyme
DB00834MifepristoneCytochrome P450 3A5enzyme
DB00834MifepristoneCytochrome P450 3A7enzyme
DB00834MifepristoneCytochrome P450 2D6enzyme
DB00834MifepristoneCytochrome P450 2C8enzyme
DB00834MifepristoneCytochrome P450 2C9enzyme
DB00834MifepristoneProgesterone receptortarget
DB00834MifepristoneGlucocorticoid receptortarget
DB00834MifepristoneProstate-specific antigentarget
DB00834MifepristoneNuclear receptor subfamily 1 group I member 2target
DB00834MifepristoneMultidrug resistance protein 1transporter
DB00834MifepristoneMultidrug resistance-associated protein 1transporter
DB00834MifepristoneBile salt export pumptransporter
DB01181IfosfamideCytochrome P450 2B6enzyme
DB01181IfosfamideCytochrome P450 3A4enzyme
DB01181IfosfamideCytochrome P450 3A5enzyme
DB01181IfosfamideCytochrome P450 2C9enzyme
DB01181IfosfamideCytochrome P450 2C8enzyme
DB01181IfosfamideCytochrome P450 2A6enzyme
DB01181IfosfamideCytochrome P450 2C19enzyme
DB01181IfosfamideCytochrome P450 2C18enzyme
DB01181IfosfamideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideDNAtarget
DB01181IfosfamideNuclear receptor subfamily 1 group I member 2target
DB00321AmitriptylineSerum albumincarrier
DB00321AmitriptylineAlpha-1-acid glycoprotein 1carrier
DB00321AmitriptylineCytochrome P450 1A2enzyme
DB00321AmitriptylineCytochrome P450 2C19enzyme
DB00321AmitriptylineCytochrome P450 2D6enzyme
DB00321AmitriptylineCytochrome P450 3A4enzyme
DB00321AmitriptylineCytochrome P450 3A5enzyme
DB00321AmitriptylineCytochrome P450 2C9enzyme
DB00321AmitriptylineCytochrome P450 2B6enzyme
DB00321AmitriptylineCytochrome P450 2C8enzyme
DB00321AmitriptylineCytochrome P450 2E1enzyme
DB00321AmitriptylineUDP-glucuronosyltransferase 1-1enzyme
DB00321AmitriptylineSodium-dependent serotonin transportertarget
DB00321AmitriptylineSodium-dependent noradrenaline transportertarget
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
DB00321AmitriptylineAlpha-2A adrenergic receptortarget
DB00321AmitriptylineMuscarinic acetylcholine receptor M1target
DB00321AmitriptylineMuscarinic acetylcholine receptor M2target
DB00321AmitriptylineMuscarinic acetylcholine receptor M3target
DB00321AmitriptylineMuscarinic acetylcholine receptor M4target
DB00321AmitriptylineMuscarinic acetylcholine receptor M5target
DB00321AmitriptylineHistamine H1 receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 2Atarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Atarget
DB00321AmitriptylineAlpha-1A adrenergic receptortarget
DB00321AmitriptylinePotassium voltage-gated channel subfamily A member 1target
DB00321AmitriptylinePotassium voltage-gated channel subfamily D member 2target
DB00321AmitriptylinePotassium voltage-gated channel subfamily D member 3target
DB00321AmitriptylineAlpha-1D adrenergic receptortarget
DB00321AmitriptylineDelta-type opioid receptortarget
DB00321AmitriptylineKappa-type opioid receptortarget
DB00321AmitriptylineHigh affinity nerve growth factor receptortarget
DB00321AmitriptylineBDNF/NT-3 growth factors receptortarget
DB00321AmitriptylineHistamine H2 receptortarget
DB00321AmitriptylineHistamine H4 receptortarget
DB00321AmitriptylineSigma non-opioid intracellular receptor 1target
DB00321Amitriptyline5-hydroxytryptamine receptor 2Ctarget
DB00321AmitriptylineAlpha-1B adrenergic receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 7target
DB00321Amitriptyline5-hydroxytryptamine receptor 1Dtarget
DB00321AmitriptylineMu-type opioid receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Btarget
DB00321Amitriptyline5-hydroxytryptamine receptor 6target
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
DB00321AmitriptylineBeta adrenergic receptortarget
DB00321AmitriptylineMultidrug resistance protein 1transporter
DB00540NortriptylineSerum albumincarrier
DB00540NortriptylineAlpha-1-acid glycoprotein 1carrier
DB00540NortriptylineCytochrome P450 1A2enzyme
DB00540NortriptylineCytochrome P450 2D6enzyme
DB00540NortriptylineCytochrome P450 3A4enzyme
DB00540NortriptylineCytochrome P450 3A5enzyme
DB00540NortriptylineCytochrome P450 2C19enzyme
DB00540NortriptylineProstaglandin G/H synthase 1enzyme
DB00540NortriptylineCytochrome P450 2E1enzyme
DB00540NortriptylineSodium-dependent serotonin transportertarget
DB00540NortriptylineSodium-dependent noradrenaline transportertarget
DB00540NortriptylineHistamine H1 receptortarget
DB00540NortriptylineMuscarinic acetylcholine receptor M1target
DB00540NortriptylineMuscarinic acetylcholine receptor M2target
DB00540NortriptylineMuscarinic acetylcholine receptor M3target
DB00540NortriptylineMuscarinic acetylcholine receptor M4target
DB00540NortriptylineMuscarinic acetylcholine receptor M5target
DB00540Nortriptyline5-hydroxytryptamine receptor 2Atarget
DB00540NortriptylineAlpha-1A adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Atarget
DB00540NortriptylineAlpha-1D adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 2Ctarget
DB00540Nortriptyline5-hydroxytryptamine receptor 6target
DB00540NortriptylineAlpha-1B adrenergic receptortarget
DB00540NortriptylineAlpha-2 adrenergic receptorstarget
DB00540NortriptylineBeta adrenergic receptortarget
DB00540NortriptylineD(2) dopamine receptortarget
DB00540NortriptylineSigma receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Ctarget
DB06652VicrivirocCytochrome P450 3A4enzyme
DB06652VicrivirocCytochrome P450 3A5enzyme
DB06652VicrivirocCytochrome P450 2C9enzyme
DB06652VicrivirocC-C chemokine receptor type 5target
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2B6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineMultidrug resistance protein 1transporter
DB00342TerfenadineCytochrome P450 3A4enzyme
DB00342TerfenadineCytochrome P450 2D6enzyme
DB00342TerfenadineCytochrome P450 3A5enzyme
DB00342TerfenadineCytochrome P450 3A7enzyme
DB00342TerfenadineCytochrome P450 2C8enzyme
DB00342TerfenadineCytochrome P450 2J2enzyme
DB00342TerfenadineHistamine H1 receptortarget
DB00342TerfenadinePotassium voltage-gated channel subfamily H member 2target
DB00342TerfenadineMuscarinic acetylcholine receptor M3target
DB00342TerfenadineMuscarinic acetylcholine receptor M1target
DB00342TerfenadineMuscarinic acetylcholine receptor M5target
DB00342TerfenadineMuscarinic acetylcholine receptor M4target
DB00342TerfenadineMuscarinic acetylcholine receptor M2target
DB00342TerfenadineMultidrug resistance protein 1transporter
DB00342TerfenadineBile salt export pumptransporter
DB00528LercanidipineCytochrome P450 3A4enzyme
DB00528LercanidipineCytochrome P450 3A5enzyme
DB00528LercanidipineCytochrome P450 3A7enzyme
DB00528LercanidipineCytochrome P450 2D6enzyme
DB00528LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
DB00439CerivastatinCytochrome P450 2C8enzyme
DB00439CerivastatinCytochrome P450 3A4enzyme
DB00439CerivastatinCytochrome P450 2D6enzyme
DB00439CerivastatinCytochrome P450 2C9enzyme
DB00439CerivastatinCytochrome P450 3A5enzyme
DB00439CerivastatinCytochrome P450 3A7enzyme
DB00439CerivastatinCytochrome P450 2B6enzyme
DB00439CerivastatinUDP-glucuronosyltransferase 1-1enzyme
DB00439Cerivastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00439CerivastatinMultidrug resistance protein 1transporter
DB00439CerivastatinCanalicular multispecific organic anion transporter 1transporter
DB00439CerivastatinATP-binding cassette sub-family G member 2transporter
DB00439CerivastatinSolute carrier organic anion transporter family member 1B1transporter
DB00439CerivastatinBile salt export pumptransporter
DB00783EstradiolSex hormone-binding globulincarrier
DB00783EstradiolSerum albumincarrier
DB00783EstradiolFatty acid-binding protein, intestinalcarrier
DB00783EstradiolCytochrome P450 1A2enzyme
DB00783EstradiolUDP-glucuronosyltransferase 1-1enzyme
DB00783EstradiolCytochrome P450 3A4enzyme
DB00783EstradiolCytochrome P450 3A5enzyme
DB00783EstradiolCytochrome P450 3A7enzyme
DB00783EstradiolCytochrome P450 1A1enzyme
DB00783EstradiolCytochrome P450 1B1enzyme
DB00783EstradiolCytochrome P450 2C19enzyme
DB00783EstradiolCytochrome P450 2C8enzyme
DB00783EstradiolCytochrome P450 2C9enzyme
DB00783EstradiolEstrogen receptor alphatarget
DB00783EstradiolNuclear receptor subfamily 1 group I member 2target
DB00783EstradiolEstrogen receptor betatarget
DB00783EstradiolNeuronal acetylcholine receptor subunit alpha-4target
DB00783EstradiolNuclear receptor coactivator 2target
DB00783EstradiolG-protein coupled estrogen receptor 1target
DB00783EstradiolATP synthase subunit atarget
DB00783EstradiolBeclin-1target
DB00783EstradiolEstradiol 17-beta-dehydrogenase 2target
DB00783EstradiolEstrogen-related receptor gammatarget
DB00783EstradiolSolute carrier family 22 member 2transporter
DB00783EstradiolSolute carrier family 22 member 1transporter
DB00783EstradiolSolute carrier family 22 member 3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 2B1transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1A2transporter
DB00783EstradiolMultidrug resistance-associated protein 7transporter
DB00783EstradiolSolute carrier family 22 member 11transporter
DB00783EstradiolATP-binding cassette sub-family G member 2transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B1transporter
DB00783EstradiolMultidrug resistance protein 1transporter
DB00783EstradiolSolute carrier family 22 member 8transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1C1transporter
DB00783EstradiolSolute carrier organic anion transporter family member 4A1transporter
DB00624TestosteroneSerum albumincarrier
DB00624TestosteroneSex hormone-binding globulincarrier
DB00624TestosteroneCytochrome P450 3A4enzyme
DB00624TestosteroneCytochrome P450 19A1enzyme
DB00624TestosteroneAmine oxidase [flavin-containing] Aenzyme
DB00624TestosteroneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00624TestosteroneCytochrome P450 3A5enzyme
DB00624TestosteroneCytochrome P450 3A7enzyme
DB00624TestosteroneCytochrome P450 1A1enzyme
DB00624TestosteroneCytochrome P450 1B1enzyme
DB00624TestosteroneCytochrome P450 2A13enzyme
DB00624TestosteroneCytochrome P450 2B6enzyme
DB00624TestosteroneCytochrome P450 2C19enzyme
DB00624TestosteroneCytochrome P450 2C8enzyme
DB00624TestosteroneCytochrome P450 2C9enzyme
DB00624TestosteroneCytochrome P450 3A43enzyme
DB00624TestosteroneAndrogen receptortarget
DB00624TestosteroneEstrogen receptor alphatarget
DB00624TestosteroneMineralocorticoid receptortarget
DB00624TestosteroneSolute carrier organic anion transporter family member 1A2transporter
DB00624TestosteroneSolute carrier family 22 member 8transporter
DB00624TestosteroneSolute carrier family 22 member 7transporter
DB00624TestosteroneMultidrug resistance protein 1transporter
DB00624TestosteroneSodium/bile acid cotransportertransporter
DB00624TestosteroneSolute carrier family 22 member 3transporter
DB00624TestosteroneSolute carrier family 22 member 4transporter
DB00624TestosteroneATP-binding cassette sub-family G member 2transporter
DB00673AprepitantCytochrome P450 3A4enzyme
DB00673AprepitantCytochrome P450 2C9enzyme
DB00673AprepitantCytochrome P450 3A5enzyme
DB00673AprepitantCytochrome P450 3A7enzyme
DB00673AprepitantCytochrome P450 2C19enzyme
DB00673AprepitantSubstance-P receptortarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 3A5enzyme
DB00201CaffeineCytochrome P450 3A7enzyme
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00201CaffeineMultidrug resistance protein 1transporter
DB01166CilostazolCytochrome P450 2C19enzyme
DB01166CilostazolCytochrome P450 3A4enzyme
DB01166CilostazolCytochrome P450 3A5enzyme
DB01166CilostazolCytochrome P450 3A7enzyme
DB01166CilostazolCytochrome P450 1A2enzyme
DB01166CilostazolCytochrome P450 2D6enzyme
DB01166CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00907CocaineCytochrome P450 3A4enzyme
DB00907CocaineCytochrome P450 3A5enzyme
DB00907CocaineCytochrome P450 3A7enzyme
DB00907CocaineCytochrome P450 2D6enzyme
DB00907CocaineCytochrome P450 2C8enzyme
DB00907CocaineSodium-dependent noradrenaline transportertarget
DB00907CocaineSodium channel protein type 5 subunit alphatarget
DB00907CocaineSodium channel protein type 11 subunit alphatarget
DB00907CocaineSodium channel protein type 10 subunit alphatarget
DB00907CocaineSodium-dependent serotonin transportertarget
DB00907CocaineSodium-dependent dopamine transportertarget
DB00907CocaineMuscarinic acetylcholine receptor M1target
DB00907CocaineMuscarinic acetylcholine receptor M2target
DB00907CocaineSigma non-opioid intracellular receptor 1target
DB00907CocaineLiver carboxylesterase 1target
DB00907CocaineSolute carrier family 22 member 2transporter
DB00318CodeineCytochrome P450 2D6enzyme
DB00318CodeineCytochrome P450 3A4enzyme
DB00318CodeineCytochrome P450 3A5enzyme
DB00318CodeineCytochrome P450 3A7enzyme
DB00318CodeineUDP-glucuronosyltransferase 2B7enzyme
DB00318CodeineUDP-glucuronosyltransferase 2B4enzyme
DB00318CodeineUDP-glucuronosyltransferase 1-1enzyme
DB00318CodeineMu-type opioid receptortarget
DB00318CodeineDelta-type opioid receptortarget
DB00318CodeineKappa-type opioid receptortarget
DB00318CodeineSolute carrier family 22 member 1transporter
DB00250DapsoneCytochrome P450 2C9enzyme
DB00250DapsoneCytochrome P450 2E1enzyme
DB00250DapsoneCytochrome P450 3A4enzyme
DB00250DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00250DapsoneProstaglandin G/H synthase 1enzyme
DB00250DapsoneProstaglandin G/H synthase 2enzyme
DB00250DapsoneCytochrome P450 2C8enzyme
DB00250DapsoneCytochrome P450 2C19enzyme
DB00250DapsoneArylamine N-acetyltransferase 2enzyme
DB00250DapsoneCytochrome P450 3A5enzyme
DB00250DapsoneCytochrome P450 3A7enzyme
DB00250DapsoneMyeloperoxidaseenzyme
DB00250DapsoneCytochrome P450 2C18enzyme
DB00250DapsoneInactive dihydropteroate synthase 2target
DB00250DapsoneDihydropteroate synthase 1target
DB00514DextromethorphanCytochrome P450 2D6enzyme
DB00514DextromethorphanCytochrome P450 3A4enzyme
DB00514DextromethorphanCytochrome P450 3A5enzyme
DB00514DextromethorphanCytochrome P450 3A7enzyme
DB00514DextromethorphanCytochrome P450 2C9enzyme
DB00514DextromethorphanCytochrome P450 2B6enzyme
DB00514DextromethorphanCytochrome P450 2C19enzyme
DB00514DextromethorphanCytochrome P450 2C8enzyme
DB00514DextromethorphanCytochrome P450 2E1enzyme
DB00514DextromethorphanSigma non-opioid intracellular receptor 1target
DB00514DextromethorphanHCG20471, isoform CRA_ctarget
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DB00514DextromethorphanSodium-dependent serotonin transportertarget
DB00514DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DB00514DextromethorphanMembrane-associated progesterone receptor component 1target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DB00514DextromethorphanMu-type opioid receptortarget
DB00514DextromethorphanDelta-type opioid receptortarget
DB00514DextromethorphanKappa-type opioid receptortarget
DB00514DextromethorphanNADPH oxidasetarget
DB00514DextromethorphanSodium-dependent noradrenaline transportertarget
DB01248DocetaxelCytochrome P450 3A4enzyme
DB01248DocetaxelCytochrome P450 3A5enzyme
DB01248DocetaxelCytochrome P450 3A7enzyme
DB01248DocetaxelCytochrome P450 1B1enzyme
DB01248DocetaxelApoptosis regulator Bcl-2target
DB01248DocetaxelTubulin beta-1 chaintarget
DB01248DocetaxelMicrotubule-associated protein 2target
DB01248DocetaxelMicrotubule-associated protein 4target
DB01248DocetaxelMicrotubule-associated protein tautarget
DB01248DocetaxelNuclear receptor subfamily 1 group I member 2target
DB01248DocetaxelMultidrug resistance protein 1transporter
DB01248DocetaxelMultidrug resistance-associated protein 7transporter
DB01248DocetaxelSolute carrier organic anion transporter family member 1B3transporter
DB01248DocetaxelSolute carrier family 22 member 7transporter
DB01248DocetaxelATP-binding cassette sub-family G member 2transporter
DB01248DocetaxelCanalicular multispecific organic anion transporter 1transporter
DB01248DocetaxelMultidrug resistance-associated protein 1transporter
DB01184DomperidoneCytochrome P450 3A4enzyme
DB01184DomperidoneCytochrome P450 3A5enzyme
DB01184DomperidoneCytochrome P450 3A7enzyme
DB01184DomperidoneCytochrome P450 1A2enzyme
DB01184DomperidoneCytochrome P450 2B6enzyme
DB01184DomperidoneCytochrome P450 2C8enzyme
DB01184DomperidoneCytochrome P450 2D6enzyme
DB01184DomperidoneD(2) dopamine receptortarget
DB01184DomperidoneD(3) dopamine receptortarget
DB01184DomperidoneMultidrug resistance protein 1transporter
DB00700EplerenoneCytochrome P450 3A4enzyme
DB00700EplerenoneCytochrome P450 3A5enzyme
DB00700EplerenoneCytochrome P450 3A7enzyme
DB00700EplerenoneCytochrome P450 11B2, mitochondrialenzyme
DB00700EplerenoneMineralocorticoid receptortarget
DB01216FinasterideCytochrome P450 3A4enzyme
DB01216FinasterideCytochrome P450 3A5enzyme
DB01216FinasterideCytochrome P450 3A7enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01216Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
DB01227Levomethadyl acetateCytochrome P450 3A4enzyme
DB01227Levomethadyl acetateCytochrome P450 3A5enzyme
DB01227Levomethadyl acetateCytochrome P450 3A7enzyme
DB01227Levomethadyl acetateCytochrome P450 19A1enzyme
DB01227Levomethadyl acetateMu-type opioid receptortarget
DB01227Levomethadyl acetateNeuronal acetylcholine receptor subunit beta-4target
DB01227Levomethadyl acetateNeuronal acetylcholine receptor subunit alpha-3target
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C18enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineMultidrug resistance protein 1transporter
DB00333MethadoneCytochrome P450 2B6enzyme
DB00333MethadoneCytochrome P450 3A4enzyme
DB00333MethadoneCytochrome P450 2C19enzyme
DB00333MethadoneCytochrome P450 3A5enzyme
DB00333MethadoneCytochrome P450 3A7enzyme
DB00333MethadoneCytochrome P450 2D6enzyme
DB00333MethadoneCytochrome P450 2C8enzyme
DB00333MethadoneCytochrome P450 19A1enzyme
DB00333MethadoneCytochrome P450 1A2enzyme
DB00333MethadoneCytochrome P450 2C18enzyme
DB00333MethadoneCytochrome P450 2C9enzyme
DB00333MethadoneGlutamate receptor ionotropic, NMDA 3Atarget
DB00333MethadoneMu-type opioid receptortarget
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-10target
DB00333MethadoneDelta-type opioid receptortarget
DB00333Methadone5-hydroxytryptamine receptor 3Atarget
DB00333MethadoneLymphocyte antigen 96target
DB00333MethadoneAlpha-1-acid glycoprotein 2target
DB00333MethadoneMultidrug resistance protein 1transporter
DB00731NateglinideSerum albumincarrier
DB00731NateglinideAlpha-1-acid glycoprotein 1carrier
DB00731NateglinideCytochrome P450 3A4enzyme
DB00731NateglinideCytochrome P450 2C9enzyme
DB00731NateglinideCytochrome P450 3A5enzyme
DB00731NateglinideCytochrome P450 3A7enzyme
DB00731NateglinideProstaglandin G/H synthase 1enzyme
DB00731NateglinideUDP-glucuronosyltransferase 1-9enzyme
DB00731NateglinideCytochrome P450 2D6enzyme
DB00731NateglinideATP-binding cassette sub-family C member 8target
DB00731NateglinidePeroxisome proliferator-activated receptor gammatarget
DB00731NateglinideSolute carrier family 15 member 1transporter
DB00731NateglinideSolute carrier family 15 member 2transporter
DB00731NateglinideSolute carrier family 22 member 6transporter
DB00731NateglinideMonocarboxylate transporter 1transporter
DB00731NateglinideMultidrug resistance-associated protein 4transporter
DB00904OndansetronCytochrome P450 3A4enzyme
DB00904OndansetronCytochrome P450 1A2enzyme
DB00904OndansetronCytochrome P450 2D6enzyme
DB00904OndansetronCytochrome P450 3A5enzyme
DB00904OndansetronCytochrome P450 3A7enzyme
DB00904OndansetronCytochrome P450 2C9enzyme
DB00904OndansetronCytochrome P450 2E1enzyme
DB00904Ondansetron5-hydroxytryptamine receptor 3Atarget
DB00904Ondansetron5-hydroxytryptamine receptor 4target
DB00904Ondansetron5-hydroxytryptamine receptor 1Atarget
DB00904Ondansetron5-hydroxytryptamine receptor 1Btarget
DB00904OndansetronMu-type opioid receptortarget
DB00571PropranololAlpha-1-acid glycoprotein 1carrier
DB00571PropranololCytochrome P450 1A2enzyme
DB00571PropranololCytochrome P450 2D6enzyme
DB00571PropranololCytochrome P450 2C19enzyme
DB00571PropranololCytochrome P450 3A4enzyme
DB00571PropranololCytochrome P450 3A5enzyme
DB00571PropranololCytochrome P450 3A7enzyme
DB00571PropranololCytochrome P450 1A1enzyme
DB00571PropranololAmine oxidase [flavin-containing] Aenzyme
DB00571PropranololBeta-1 adrenergic receptortarget
DB00571PropranololBeta-2 adrenergic receptortarget
DB00571PropranololBeta-3 adrenergic receptortarget
DB00571Propranolol5-hydroxytryptamine receptor 1Atarget
DB00571Propranolol5-hydroxytryptamine receptor 1Btarget
DB00571PropranololSolute carrier family 22 member 2transporter
DB00571PropranololMultidrug resistance protein 1transporter
DB01224QuetiapineCytochrome P450 3A4enzyme
DB01224QuetiapineCytochrome P450 3A5enzyme
DB01224QuetiapineCytochrome P450 3A7enzyme
DB01224QuetiapineCytochrome P450 2C19enzyme
DB01224QuetiapineCytochrome P450 2D6enzyme
DB01224Quetiapine5-hydroxytryptamine receptor 2Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Ctarget
DB01224QuetiapineD(2) dopamine receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Atarget
DB01224QuetiapineHistamine H1 receptortarget
DB01224QuetiapineAlpha-1A adrenergic receptortarget
DB01224QuetiapineAlpha-1B adrenergic receptortarget
DB01224QuetiapineAlpha-1D adrenergic receptortarget
DB01224QuetiapineAlpha-2A adrenergic receptortarget
DB01224QuetiapineAlpha-2B adrenergic receptortarget
DB01224QuetiapineAlpha-2C adrenergic receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Dtarget
DB01224QuetiapineMuscarinic acetylcholine receptor M1target
DB01224QuetiapineMuscarinic acetylcholine receptor M2target
DB01224QuetiapineMuscarinic acetylcholine receptor M3target
DB01224QuetiapineMuscarinic acetylcholine receptor M4target
DB01224QuetiapineMuscarinic acetylcholine receptor M5target
DB01224Quetiapine5-hydroxytryptamine receptor 1Btarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Etarget
DB01224Quetiapine5-hydroxytryptamine receptor 3Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 6target
DB01224Quetiapine5-hydroxytryptamine receptor 7target
DB01224QuetiapineD(1B) dopamine receptortarget
DB01224QuetiapineD(1A) dopamine receptortarget
DB01224QuetiapineD(3) dopamine receptortarget
DB01224QuetiapineD(4) dopamine receptortarget
DB01224QuetiapineMultidrug resistance protein 1transporter
DB00938SalmeterolCytochrome P450 3A4enzyme
DB00938SalmeterolCytochrome P450 2C8enzyme
DB00938SalmeterolCytochrome P450 3A5enzyme
DB00938SalmeterolCytochrome P450 3A7enzyme
DB00938SalmeterolBeta-2 adrenergic receptortarget
DB00938SalmeterolBeta-1 adrenergic receptortarget
DB00938SalmeterolBeta-3 adrenergic receptortarget
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibMultidrug resistance protein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB01268SunitinibCytochrome P450 3A4enzyme
DB01268SunitinibCytochrome P450 3A5enzyme
DB01268SunitinibCytochrome P450 3A7enzyme
DB01268SunitinibPlatelet-derived growth factor receptor betatarget
DB01268SunitinibVascular endothelial growth factor receptor 1target
DB01268SunitinibVascular endothelial growth factor receptor 2target
DB01268SunitinibVascular endothelial growth factor receptor 3target
DB01268SunitinibMast/stem cell growth factor receptor Kittarget
DB01268SunitinibReceptor-type tyrosine-protein kinase FLT3target
DB01268SunitinibMacrophage colony-stimulating factor 1 receptortarget
DB01268SunitinibPlatelet-derived growth factor receptor alphatarget
DB01268SunitinibMultidrug resistance-associated protein 4transporter
DB01268SunitinibMultidrug resistance protein 1transporter
DB01268SunitinibCanalicular multispecific organic anion transporter 1transporter
DB01268SunitinibATP-binding cassette sub-family G member 2transporter
DB01229PaclitaxelCytochrome P450 2C8enzyme
DB01229PaclitaxelCytochrome P450 3A4enzyme
DB01229PaclitaxelCytochrome P450 3A5enzyme
DB01229PaclitaxelCytochrome P450 3A7enzyme
DB01229PaclitaxelCytochrome P450 19A1enzyme
DB01229PaclitaxelCytochrome P450 1B1enzyme
DB01229PaclitaxelApoptosis regulator Bcl-2target
DB01229PaclitaxelTubulin beta-1 chaintarget
DB01229PaclitaxelNuclear receptor subfamily 1 group I member 2target
DB01229PaclitaxelMicrotubule-associated protein 4target
DB01229PaclitaxelMicrotubule-associated protein 2target
DB01229PaclitaxelMicrotubule-associated protein tautarget
DB01229PaclitaxelBile salt export pumptransporter
DB01229PaclitaxelMultidrug resistance protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 7transporter
DB01229PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
DB01229PaclitaxelATP-binding cassette sub-family G member 2transporter
DB01229PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DB00962ZaleplonCytochrome P450 3A4enzyme
DB00962ZaleplonAldehyde oxidaseenzyme
DB00962ZaleplonCytochrome P450 3A5enzyme
DB00962ZaleplonCytochrome P450 3A7enzyme
DB00962ZaleplonTranslocator proteintarget
DB00962ZaleplonGamma-aminobutyric acid receptor subunit alpha-1target
DB00246ZiprasidoneCytochrome P450 3A4enzyme
DB00246ZiprasidoneCytochrome P450 3A5enzyme
DB00246ZiprasidoneCytochrome P450 3A7enzyme
DB00246ZiprasidoneCytochrome P450 1A2enzyme
DB00246ZiprasidoneCytochrome P450 2D6enzyme
DB00246ZiprasidoneAlpha-1A adrenergic receptortarget
DB00246ZiprasidoneD(2) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Ctarget
DB00246ZiprasidoneD(3) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Dtarget
DB00246ZiprasidoneHistamine H1 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Atarget
DB00246ZiprasidoneD(4) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 7target
DB00246ZiprasidoneAlpha-2A adrenergic receptortarget
DB00246ZiprasidoneAlpha-1B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2C adrenergic receptortarget
DB00246ZiprasidoneD(1A) dopamine receptortarget
DB00246ZiprasidoneD(1B) dopamine receptortarget
DB00246ZiprasidoneMuscarinic acetylcholine receptor M1target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M2target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M3target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M4target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M5target
DB00246Ziprasidone5-hydroxytryptamine receptor 1Btarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Etarget
DB00246Ziprasidone5-hydroxytryptamine receptor 3Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 6target
DB00425ZolpidemCytochrome P450 3A4enzyme
DB00425ZolpidemCytochrome P450 1A2enzyme
DB00425ZolpidemCytochrome P450 3A5enzyme
DB00425ZolpidemCytochrome P450 3A7enzyme
DB00425ZolpidemCytochrome P450 2C9enzyme
DB00425ZolpidemCytochrome P450 2C19enzyme
DB00425ZolpidemCytochrome P450 2D6enzyme
DB00425ZolpidemProstaglandin G/H synthase 1enzyme
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit beta-3target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
DB00921BuprenorphineCytochrome P450 3A4enzyme
DB00921BuprenorphineCytochrome P450 2D6enzyme
DB00921BuprenorphineCytochrome P450 2C9enzyme
DB00921BuprenorphineCytochrome P450 3A5enzyme
DB00921BuprenorphineCytochrome P450 2C8enzyme
DB00921BuprenorphineCytochrome P450 3A7enzyme
DB00921BuprenorphineUDP-glucuronosyltransferase 1-9enzyme
DB00921BuprenorphineCytochrome P450 2A6enzyme
DB00921BuprenorphineCytochrome P450 2C18enzyme
DB00921BuprenorphineCytochrome P450 2C19enzyme
DB00921BuprenorphineUDP-glucuronosyltransferase 1-1enzyme
DB00921BuprenorphineKappa-type opioid receptortarget
DB00921BuprenorphineMu-type opioid receptortarget
DB00921BuprenorphineDelta-type opioid receptortarget
DB00921BuprenorphineNociceptin receptortarget
DB00921BuprenorphineMultidrug resistance protein 1transporter
DB00921BuprenorphineATP-binding cassette sub-family G member 2transporter
DB06772CabazitaxelCytochrome P450 3A4enzyme
DB06772CabazitaxelCytochrome P450 3A5enzyme
DB06772CabazitaxelCytochrome P450 2C8enzyme
DB06772CabazitaxelTubulin alpha-4A chaintarget
DB06772CabazitaxelTubulin beta-1 chaintarget
DB06772CabazitaxelMultidrug resistance protein 1transporter
DB06772CabazitaxelATP-binding cassette sub-family G member 2transporter
DB06772CabazitaxelSolute carrier organic anion transporter family member 1B1transporter
DB06772CabazitaxelSolute carrier organic anion transporter family member 1B3transporter
DB06697ArtemetherCytochrome P450 3A4enzyme
DB06697ArtemetherCytochrome P450 3A5enzyme
DB06697ArtemetherCytochrome P450 2B6enzyme
DB06697ArtemetherCytochrome P450 2C9enzyme
DB06697ArtemetherCytochrome P450 2C19enzyme
DB06697ArtemetherCytochrome P450 2D6enzyme
DB00701AmprenavirCytochrome P450 3A4enzyme
DB00701AmprenavirCytochrome P450 2B6enzyme
DB00701AmprenavirCytochrome P450 2C19enzyme
DB00701AmprenavirCytochrome P450 2C8enzyme
DB00701AmprenavirCytochrome P450 2C9enzyme
DB00701AmprenavirCytochrome P450 2D6enzyme
DB00701AmprenavirCytochrome P450 3A5enzyme
DB00701AmprenavirHuman immunodeficiency virus type 1 proteasetarget
DB00701AmprenavirMultidrug resistance protein 1transporter
DB00701AmprenavirMultidrug resistance-associated protein 1transporter
DB00701AmprenavirSolute carrier organic anion transporter family member 1B1transporter
DB00278ArgatrobanCytochrome P450 3A4enzyme
DB00278ArgatrobanCytochrome P450 3A5enzyme
DB00278ArgatrobanProthrombintarget
DB00608ChloroquineCytochrome P450 2D6enzyme
DB00608ChloroquineCytochrome P450 3A4enzyme
DB00608ChloroquineCytochrome P450 1A1enzyme
DB00608ChloroquineCytochrome P450 2C8enzyme
DB00608ChloroquineCytochrome P450 3A5enzyme
DB00608ChloroquineTumor necrosis factortarget
DB00608ChloroquineToll-like receptor 9target
DB00608ChloroquineGlutathione S-transferase A2target
DB00608ChloroquineFe(II)-protoporphyrin IXtarget
DB00608ChloroquineGlutathione S-transferasetarget
DB00608ChloroquineMultidrug resistance protein 1transporter
DB00822DisulfiramCytochrome P450 2E1enzyme
DB00822DisulfiramCytochrome P450 3A4enzyme
DB00822DisulfiramCytochrome P450 3A5enzyme
DB00822DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DB00822DisulfiramDopamine beta-hydroxylasetarget
DB00822DisulfiramBile salt export pumptransporter
DB00655EstroneSerum albumincarrier
DB00655EstroneCytochrome P450 1A2enzyme
DB00655EstroneCytochrome P450 1A1enzyme
DB00655EstroneCytochrome P450 3A4enzyme
DB00655EstroneCytochrome P450 1B1enzyme
DB00655EstroneCytochrome P450 2B6enzyme
DB00655EstroneCytochrome P450 2C9enzyme
DB00655EstroneCytochrome P450 2E1enzyme
DB00655EstroneCytochrome P450 3A5enzyme
DB00655EstroneCytochrome P450 4A11enzyme
DB00655EstroneEstrogen receptor alphatarget
DB00655EstroneEstrogen receptor betatarget
DB00655EstroneAndrogen receptortarget
DB00655EstroneCytochrome P450 19A1target
DB00655EstroneSex hormone-binding globulintarget
DB00655EstroneSolute carrier organic anion transporter family member 2B1transporter
DB00655EstroneMultidrug resistance protein 1transporter
DB00655EstroneSolute carrier organic anion transporter family member 1A2transporter
DB00655EstroneATP-binding cassette sub-family G member 2transporter
DB00655EstroneSolute carrier organic anion transporter family member 1B1transporter
DB00655EstroneSolute carrier family 22 member 8transporter
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2C8enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideMultidrug resistance protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00499FlutamideCytochrome P450 1A2enzyme
DB00499FlutamideCytochrome P450 3A4enzyme
DB00499FlutamideCytochrome P450 1A1enzyme
DB00499FlutamideCytochrome P450 1B1enzyme
DB00499FlutamideCytochrome P450 2C19enzyme
DB00499FlutamideCytochrome P450 3A5enzyme
DB00499FlutamideAndrogen receptortarget
DB00499FlutamideAryl hydrocarbon receptortarget
DB00499FlutamideNuclear receptor subfamily 1 group I member 2target
DB01218HalofantrineCytochrome P450 3A4enzyme
DB01218HalofantrineCytochrome P450 2D6enzyme
DB01218HalofantrineCytochrome P450 2C8enzyme
DB01218HalofantrineCytochrome P450 3A5enzyme
DB01218HalofantrineFe(II)-protoporphyrin IXtarget
DB01218HalofantrinePotassium voltage-gated channel subfamily H member 2target
DB01218HalofantrinePlasmepsin-2target
DB01103QuinacrineHistamine N-methyltransferaseenzyme
DB01103QuinacrineCytochrome P450 3A4enzyme
DB01103QuinacrineCytochrome P450 3A5enzyme
DB01103QuinacrineDNAtarget
DB01103Quinacrine85/88 kDa calcium-independent phospholipase A2target
DB01103QuinacrineCytosolic phospholipase A2target
DB01103QuinacrineInactive phospholipase C-like protein 1target
DB01103QuinacrineSolute carrier family 22 member 2transporter
DB01103QuinacrineMultidrug resistance protein 1transporter
DB01062OxybutyninCytochrome P450 3A4enzyme
DB01062OxybutyninCytochrome P450 2C8enzyme
DB01062OxybutyninCytochrome P450 2D6enzyme
DB01062OxybutyninCytochrome P450 3A5enzyme
DB01062OxybutyninMuscarinic acetylcholine receptor M1target
DB01062OxybutyninMuscarinic acetylcholine receptor M2target
DB01062OxybutyninMuscarinic acetylcholine receptor M3target
DB00497OxycodoneCytochrome P450 2D6enzyme
DB00497OxycodoneCytochrome P450 3A4enzyme
DB00497OxycodoneCytochrome P450 3A5enzyme
DB00497OxycodoneMu-type opioid receptortarget
DB00497OxycodoneKappa-type opioid receptortarget
DB00497OxycodoneDelta-type opioid receptortarget
DB00497OxycodoneKappa-type opioid receptor 2btarget
DB00497Oxycodonealpha1-acid glycoproteintarget
DB01058PraziquantelCytochrome P450 3A4enzyme
DB01058PraziquantelCytochrome P450 1A2enzyme
DB01058PraziquantelCytochrome P450 2C19enzyme
DB01058PraziquantelCytochrome P450 3A43enzyme
DB01058PraziquantelCytochrome P450 3A5enzyme
DB01058PraziquantelCytochrome P450 3A7enzyme
DB01058PraziquantelSchistosome calcium ion (Ca2+) channelstarget
DB00444TeniposideCytochrome P450 2C19enzyme
DB00444TeniposideCytochrome P450 2C9enzyme
DB00444TeniposideCytochrome P450 3A4enzyme
DB00444TeniposideCytochrome P450 3A5enzyme
DB00444TeniposideDNA topoisomerase 2-alphatarget
DB00444TeniposideMultidrug resistance-associated protein 6transporter
DB00444TeniposideATP-binding cassette sub-family G member 2transporter
DB00530ErlotinibSerum albumincarrier
DB00530ErlotinibAlpha-1-acid glycoprotein 1carrier
DB00530ErlotinibCytochrome P450 3A4enzyme
DB00530ErlotinibCytochrome P450 3A5enzyme
DB00530ErlotinibCytochrome P450 1A1enzyme
DB00530ErlotinibCytochrome P450 1A2enzyme
DB00530ErlotinibCytochrome P450 1B1enzyme
DB00530ErlotinibCytochrome P450 2D6enzyme
DB00530ErlotinibCytochrome P450 2C8enzyme
DB00530ErlotinibUDP-glucuronosyltransferase 1-1enzyme
DB00530ErlotinibEpidermal growth factor receptortarget
DB00530ErlotinibNuclear receptor subfamily 1 group I member 2target
DB00530ErlotinibATP-binding cassette sub-family G member 2transporter
DB00530ErlotinibMultidrug resistance protein 1transporter
DB00530ErlotinibSolute carrier organic anion transporter family member 2B1transporter
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateMultidrug resistance protein 1carrier
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00755TretinoinSerum albumincarrier
DB00755TretinoinCytochrome P450 2C8enzyme
DB00755TretinoinCytochrome P450 2B6enzyme
DB00755TretinoinCytochrome P450 3A4enzyme
DB00755TretinoinCytochrome P450 3A5enzyme
DB00755TretinoinCytochrome P450 2A6enzyme
DB00755TretinoinCytochrome P450 3A7enzyme
DB00755TretinoinCytochrome P450 2C18enzyme
DB00755TretinoinCytochrome P450 2C9enzyme
DB00755TretinoinCytochrome P450 4A11enzyme
DB00755TretinoinCytochrome P450 1A1enzyme
DB00755TretinoinRetinoic acid receptor gammatarget
DB00755TretinoinRetinoic acid receptor RXR-betatarget
DB00755TretinoinRetinal dehydrogenase 1target
DB00755TretinoinRetinoic acid-induced protein 3target
DB00755TretinoinRetinoic acid receptor RXR-gammatarget
DB00755TretinoinNuclear receptor subfamily 0 group B member 1target
DB00755TretinoinRetinal dehydrogenase 2target
DB00755TretinoinRetinoic acid receptor responder protein 1target
DB00755TretinoinRetinoic acid receptor alphatarget
DB00755TretinoinRetinoic acid receptor betatarget
DB00755TretinoinLipocalin-1target
DB00755TretinoinOdorant-binding protein 2atarget
DB00755TretinoinRetinol-binding protein 4target
DB00755Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
DB00755TretinoinRetinoic acid receptor RXR-alphatarget
DB00755TretinoinCytochrome P450 26A1target
DB00755TretinoinCytochrome P450 26B1target
DB00755TretinoinCytochrome P450 26C1target
DB00755TretinoinHematopoietic prostaglandin D synthasetarget
DB00755TretinoinCellular retinoic acid-binding protein 1transporter
DB00755TretinoinCellular retinoic acid-binding protein 2transporter
DB01254DasatinibCytochrome P450 3A4enzyme
DB01254DasatinibCytochrome P450 1A1enzyme
DB01254DasatinibCytochrome P450 1A2enzyme
DB01254DasatinibCytochrome P450 1B1enzyme
DB01254DasatinibCytochrome P450 3A5enzyme
DB01254DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01254DasatinibTyrosine-protein kinase ABL1target
DB01254DasatinibAbelson tyrosine-protein kinase 2target
DB01254DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DB01254DasatinibTyrosine-protein kinase Fyntarget
DB01254DasatinibTyrosine-protein kinase Lcktarget
DB01254DasatinibTyrosine-protein kinase Yestarget
DB01254DasatinibMast/stem cell growth factor receptor Kittarget
DB01254DasatinibPlatelet-derived growth factor receptor betatarget
DB01254DasatinibEphrin type-A receptor 2target
DB01254DasatinibSignal transducer and activator of transcription 5Btarget
DB01254DasatinibTyrosine-protein kinase BTKtarget
DB01254DasatinibNuclear receptor subfamily 4 group A member 3target
DB01254DasatinibBreakpoint cluster region proteintarget
DB01254DasatinibTyrosine-protein kinase CSKtarget
DB01254DasatinibEphrin type-A receptor 5target
DB01254DasatinibEphrin type-B receptor 4target
DB01254DasatinibTyrosine-protein kinase Fgrtarget
DB01254DasatinibTyrosine-protein kinase FRKtarget
DB01254DasatinibHeat shock cognate 71 kDa proteintarget
DB01254DasatinibTyrosine-protein kinase Lyntarget
DB01254DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DB01254DasatinibMitogen-activated protein kinase 14target
DB01254DasatinibAmidophosphoribosyltransferasetarget
DB01254DasatinibMultidrug resistance protein 1transporter
DB01254DasatinibATP-binding cassette sub-family G member 2transporter
DB04946IloperidoneCytochrome P450 2D6enzyme
DB04946IloperidoneCytochrome P450 3A4enzyme
DB04946IloperidoneCytochrome P450 3A5enzyme
DB04946IloperidoneCytochrome P450 3A7enzyme
DB04946IloperidoneCytochrome P450 2E1enzyme
DB04946IloperidoneD(2) dopamine receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 2Atarget
DB04946IloperidoneD(3) dopamine receptortarget
DB04946IloperidoneAlpha-1A adrenergic receptortarget
DB04946IloperidoneD(4) dopamine receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 6target
DB04946Iloperidone5-hydroxytryptamine receptor 7target
DB04946IloperidoneHistamine H1 receptortarget
DB04946IloperidoneD(1A) dopamine receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 1Atarget
DB04946IloperidoneAlpha-2C adrenergic receptortarget
DB06176RomidepsinCytochrome P450 3A4enzyme
DB06176RomidepsinCytochrome P450 3A5enzyme
DB06176RomidepsinCytochrome P450 1A1enzyme
DB06176RomidepsinCytochrome P450 2B6enzyme
DB06176RomidepsinCytochrome P450 2C19enzyme
DB06176RomidepsinHistone deacetylase 1target
DB06176RomidepsinHistone deacetylase 2target
DB06176RomidepsinHistone deacetylase 4target
DB06176RomidepsinHistone deacetylase 6target
DB06176RomidepsinMultidrug resistance-associated protein 1target
DB06176RomidepsinMultidrug resistance protein 1transporter
DB06176RomidepsinSolute carrier organic anion transporter family member 1B3transporter
DB06335SaxagliptinCytochrome P450 3A4enzyme
DB06335SaxagliptinCytochrome P450 3A5enzyme
DB06335SaxagliptinDipeptidyl peptidase 4target
DB06335SaxagliptinMultidrug resistance-associated protein 1transporter
DB06335SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
DB06335SaxagliptinSolute carrier family 22 member 8transporter
DB00575ClonidineCytochrome P450 2D6enzyme
DB00575ClonidineCytochrome P450 1A2enzyme
DB00575ClonidineCytochrome P450 3A4enzyme
DB00575ClonidineCytochrome P450 1A1enzyme
DB00575ClonidineCytochrome P450 3A5enzyme
DB00575ClonidineAlpha-2A adrenergic receptortarget
DB00575ClonidineAlpha-2B adrenergic receptortarget
DB00575ClonidineAlpha-2C adrenergic receptortarget
DB00575ClonidineAlpha-1A adrenergic receptortarget
DB00575ClonidineAlpha-1B adrenergic receptortarget
DB00575ClonidineAlpha-1D adrenergic receptortarget
DB00575ClonidineSolute carrier family 22 member 3transporter
DB00575ClonidineSolute carrier family 22 member 5transporter
DB00575ClonidineSolute carrier family 22 member 4transporter
DB00575ClonidineMultidrug resistance protein 1transporter
DB06419CethromycinCytochrome P450 3A5enzyme
DB06419CethromycinCytochrome P450 3A4enzyme
DB06419Cethromycin23S rRNAtarget
DB06228RivaroxabanCytochrome P450 3A4enzyme
DB06228RivaroxabanCytochrome P450 2J2enzyme
DB06228RivaroxabanCytochrome P450 3A5enzyme
DB06228RivaroxabanCoagulation factor Xtarget
DB06228RivaroxabanMultidrug resistance protein 1transporter
DB06228RivaroxabanATP-binding cassette sub-family G member 2transporter
DB06605ApixabanCytochrome P450 3A4enzyme
DB06605ApixabanCytochrome P450 1A2enzyme
DB06605ApixabanCytochrome P450 2C8enzyme
DB06605ApixabanCytochrome P450 2C9enzyme
DB06605ApixabanCytochrome P450 2C19enzyme
DB06605ApixabanCytochrome P450 2J2enzyme
DB06605ApixabanCytochrome P450 3A5enzyme
DB06605ApixabanCoagulation factor Xtarget
DB06605ApixabanMultidrug resistance protein 1transporter
DB06605ApixabanATP-binding cassette sub-family G member 2transporter
DB08901PonatinibCytochrome P450 3A4enzyme
DB08901PonatinibCytochrome P450 2C8enzyme
DB08901PonatinibCytochrome P450 2D6enzyme
DB08901PonatinibCytochrome P450 3A5enzyme
DB08901PonatinibTyrosine-protein kinase ABL1target
DB08901PonatinibBreakpoint cluster region proteintarget
DB08901PonatinibMast/stem cell growth factor receptor Kittarget
DB08901PonatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB08901PonatinibAngiopoietin-1 receptortarget
DB08901PonatinibReceptor-type tyrosine-protein kinase FLT3target
DB08901PonatinibFibroblast growth factor receptor 1target
DB08901PonatinibFibroblast growth factor receptor 2target
DB08901PonatinibFibroblast growth factor receptor 3target
DB08901PonatinibFibroblast growth factor receptor 4target
DB08901PonatinibTyrosine-protein kinase Lcktarget
DB08901PonatinibProto-oncogene tyrosine-protein kinase Srctarget
DB08901PonatinibTyrosine-protein kinase Lyntarget
DB08901PonatinibVascular endothelial growth factor receptor 2target
DB08901PonatinibPlatelet-derived growth factor receptor alphatarget
DB08901PonatinibMultidrug resistance protein 1transporter
DB08901PonatinibATP-binding cassette sub-family G member 2transporter
DB05773Trastuzumab emtansineCytochrome P450 3A4enzyme
DB05773Trastuzumab emtansineCytochrome P450 3A5enzyme
DB05773Trastuzumab emtansineReceptor tyrosine-protein kinase erbB-2target
DB05773Trastuzumab emtansineMultidrug resistance protein 1transporter
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB00688Mycophenolate mofetilSerum albumincarrier
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-1enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-7enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-6enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-9enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 2B7enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-8enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-10enzyme
DB00688Mycophenolate mofetilLiver carboxylesterase 1enzyme
DB00688Mycophenolate mofetilCocaine esteraseenzyme
DB00688Mycophenolate mofetilCytochrome P450 3A4enzyme
DB00688Mycophenolate mofetilCytochrome P450 3A5enzyme
DB00688Mycophenolate mofetilCytochrome P450 2C8enzyme
DB00688Mycophenolate mofetilInosine-5'-monophosphate dehydrogenase 2target
DB00688Mycophenolate mofetilInosine-5'-monophosphate dehydrogenase 1target
DB00688Mycophenolate mofetilSolute carrier organic anion transporter family member 1B1transporter
DB00688Mycophenolate mofetilSolute carrier organic anion transporter family member 1B3transporter
DB00688Mycophenolate mofetilCanalicular multispecific organic anion transporter 1transporter
DB00688Mycophenolate mofetilATP-binding cassette sub-family G member 2transporter
DB00688Mycophenolate mofetilMultidrug resistance protein 1transporter
DB09053IbrutinibSerum albumincarrier
DB09053Ibrutinibalpha1-acid glycoproteincarrier
DB09053IbrutinibCytochrome P450 3A4enzyme
DB09053IbrutinibCytochrome P450 3A5enzyme
DB09053IbrutinibCytochrome P450 2D6enzyme
DB09053IbrutinibTyrosine-protein kinase BTKtarget
DB09102DaclatasvirCytochrome P450 3A5enzyme
DB09102DaclatasvirCytochrome P450 3A4enzyme
DB09102DaclatasvirCytochrome P450 3A43enzyme
DB09102DaclatasvirCytochrome P450 3A7enzyme
DB09102DaclatasvirCytochrome P450 3A3enzyme
DB09102DaclatasvirNonstructural Protein 5A (NS5A)target
DB09102DaclatasvirMultidrug resistance protein 1transporter
DB09102DaclatasvirSolute carrier organic anion transporter family member 1B1transporter
DB09102DaclatasvirSolute carrier organic anion transporter family member 1B3transporter
DB09102DaclatasvirATP-binding cassette sub-family G member 2transporter
DB06403AmbrisentanCytochrome P450 2C19enzyme
DB06403AmbrisentanCytochrome P450 3A4enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
DB06403AmbrisentanCytochrome P450 3A5enzyme
DB06403AmbrisentanEndothelin B receptortarget
DB06403AmbrisentanEndothelin-1 receptortarget
DB06403AmbrisentanMultidrug resistance protein 1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
DB12161DeutetrabenazineCarbonyl reductase [NADPH] 1enzyme
DB12161DeutetrabenazineCarbonyl reductase [NADPH] 3enzyme
DB12161DeutetrabenazineCytochrome P450 2D6enzyme
DB12161DeutetrabenazineCytochrome P450 1A2enzyme
DB12161DeutetrabenazineCytochrome P450 3A5enzyme
DB12161DeutetrabenazineCytochrome P450 3A4enzyme
DB12161DeutetrabenazineSynaptic vesicular amine transportertarget
DB11915ValbenazineCytochrome P450 2D6enzyme
DB11915ValbenazineCytochrome P450 3A4enzyme
DB11915ValbenazineCytochrome P450 3A5enzyme
DB11915Valbenazinevesicular monoamine transporter 2 (VMAT2)target
DB08820IvacaftorSerum albumincarrier
DB08820IvacaftorAlpha-1-acid glycoprotein 1carrier
DB08820IvacaftorCytochrome P450 3A4enzyme
DB08820IvacaftorCytochrome P450 3A5enzyme
DB08820IvacaftorCystic fibrosis transmembrane conductance regulatortarget
DB08820IvacaftorMultidrug resistance protein 1transporter
DB09054IdelalisibAldehyde oxidaseenzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1A4enzyme
DB09054IdelalisibUDP-glucuronosyltransferase 1A1enzyme
DB09054IdelalisibCytochrome P450 2C8enzyme
DB09054IdelalisibCytochrome P450 2C19enzyme
DB09054IdelalisibCytochrome P450 2B6enzyme
DB09054IdelalisibCytochrome P450 3A4enzyme
DB09054IdelalisibCytochrome P450 3A5enzyme
DB09054IdelalisibCytochrome P450 3A43enzyme
DB09054IdelalisibCytochrome P450 3A7enzyme
DB09054IdelalisibPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (P110δ)target
DB09054IdelalisibATP-binding cassette sub-family G member 2transporter
DB09054IdelalisibMultidrug resistance protein 1transporter
DB09054IdelalisibSolute carrier organic anion transporter family member 1B1transporter
DB09054IdelalisibSolute carrier organic anion transporter family member 1B3transporter
DB09065CobicistatCytochrome P450 2D6enzyme
DB09065CobicistatCytochrome P450 3A4enzyme
DB09065CobicistatCytochrome P450 3A5enzyme
DB09065CobicistatCytochrome P450 3A7enzyme
DB09065CobicistatCytochrome P450 3A43enzyme
DB09065CobicistatMultidrug resistance protein 1transporter
DB09065CobicistatATP-binding cassette sub-family G member 2transporter
DB09065CobicistatSolute carrier organic anion transporter family member 1B1transporter
DB09065CobicistatSolute carrier organic anion transporter family member 1B3transporter
DB11574ElbasvirCytochrome P450 3A4enzyme
DB11574ElbasvirCytochrome P450 3A5enzyme
DB11574ElbasvirCytochrome P450 3A7enzyme
DB11574ElbasvirCytochrome P450 3A43enzyme
DB11574ElbasvirNonstructural Protein 5A (NS5A)target
DB11574ElbasvirMultidrug resistance protein 1transporter
DB12483CopanlisibSerum albumincarrier
DB12483CopanlisibCytochrome P450 3A4enzyme
DB12483CopanlisibCytochrome P450 3A5enzyme
DB12483CopanlisibCytochrome P450 3A7enzyme
DB12483CopanlisibCytochrome P450 3A43enzyme
DB12483CopanlisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB12483CopanlisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB12483CopanlisibMultidrug resistance protein 1transporter
DB12483CopanlisibATP-binding cassette sub-family G member 2transporter
DB12483CopanlisibMultidrug and toxin extrusion protein 2transporter
DB13943Testosterone cypionateSerum albumincarrier
DB13943Testosterone cypionateSex hormone-binding globulincarrier
DB13943Testosterone cypionateCytochrome P450 3A4enzyme
DB13943Testosterone cypionateCytochrome P450 19A1enzyme
DB13943Testosterone cypionateAmine oxidase [flavin-containing] Aenzyme
DB13943Testosterone cypionateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB13943Testosterone cypionateCytochrome P450 3A5enzyme
DB13943Testosterone cypionateCytochrome P450 3A7enzyme
DB13943Testosterone cypionateCytochrome P450 1A1enzyme
DB13943Testosterone cypionateCytochrome P450 1B1enzyme
DB13943Testosterone cypionateCytochrome P450 2A13enzyme
DB13943Testosterone cypionateCytochrome P450 2B6enzyme
DB13943Testosterone cypionateCytochrome P450 2C19enzyme
DB13943Testosterone cypionateCytochrome P450 2C8enzyme
DB13943Testosterone cypionateCytochrome P450 2C9enzyme
DB13943Testosterone cypionateCytochrome P450 3A43enzyme
DB13943Testosterone cypionate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
DB13943Testosterone cypionateAndrogen receptortarget
DB13943Testosterone cypionateEstrogen receptor alphatarget
DB13943Testosterone cypionateMineralocorticoid receptortarget
DB13943Testosterone cypionateSolute carrier organic anion transporter family member 1A2transporter
DB13943Testosterone cypionateSolute carrier family 22 member 8transporter
DB13943Testosterone cypionateSolute carrier family 22 member 7transporter
DB13943Testosterone cypionateMultidrug resistance protein 1transporter
DB13943Testosterone cypionateSodium/bile acid cotransportertransporter
DB13943Testosterone cypionateSolute carrier family 22 member 3transporter
DB13943Testosterone cypionateSolute carrier family 22 member 4transporter
DB13943Testosterone cypionateATP-binding cassette sub-family G member 2transporter
DB13944Testosterone enanthateSerum albumincarrier
DB13944Testosterone enanthateSex hormone-binding globulincarrier
DB13944Testosterone enanthateCytochrome P450 3A4enzyme
DB13944Testosterone enanthateCytochrome P450 19A1enzyme
DB13944Testosterone enanthateAmine oxidase [flavin-containing] Aenzyme
DB13944Testosterone enanthateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB13944Testosterone enanthateCytochrome P450 3A5enzyme
DB13944Testosterone enanthateCytochrome P450 3A7enzyme
DB13944Testosterone enanthateCytochrome P450 1A1enzyme
DB13944Testosterone enanthateCytochrome P450 1B1enzyme
DB13944Testosterone enanthateCytochrome P450 2A13enzyme
DB13944Testosterone enanthateCytochrome P450 2B6enzyme
DB13944Testosterone enanthateCytochrome P450 2C19enzyme
DB13944Testosterone enanthateCytochrome P450 2C8enzyme
DB13944Testosterone enanthateCytochrome P450 2C9enzyme
DB13944Testosterone enanthateCytochrome P450 3A43enzyme
DB13944Testosterone enanthate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
DB13944Testosterone enanthateAndrogen receptortarget
DB13944Testosterone enanthateEstrogen receptor alphatarget
DB13944Testosterone enanthateMineralocorticoid receptortarget
DB13944Testosterone enanthateSolute carrier organic anion transporter family member 1A2transporter
DB13944Testosterone enanthateSolute carrier family 22 member 8transporter
DB13944Testosterone enanthateSolute carrier family 22 member 7transporter
DB13944Testosterone enanthateMultidrug resistance protein 1transporter
DB13944Testosterone enanthateSodium/bile acid cotransportertransporter
DB13944Testosterone enanthateSolute carrier family 22 member 3transporter
DB13944Testosterone enanthateSolute carrier family 22 member 4transporter
DB13944Testosterone enanthateATP-binding cassette sub-family G member 2transporter
DB13946Testosterone undecanoateSerum albumincarrier
DB13946Testosterone undecanoateSex hormone-binding globulincarrier
DB13946Testosterone undecanoateCytochrome P450 3A4enzyme
DB13946Testosterone undecanoateCytochrome P450 19A1enzyme
DB13946Testosterone undecanoateAmine oxidase [flavin-containing] Aenzyme
DB13946Testosterone undecanoateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB13946Testosterone undecanoateCytochrome P450 3A5enzyme
DB13946Testosterone undecanoateCytochrome P450 3A7enzyme
DB13946Testosterone undecanoateCytochrome P450 1A1enzyme
DB13946Testosterone undecanoateCytochrome P450 1B1enzyme
DB13946Testosterone undecanoateCytochrome P450 2A13enzyme
DB13946Testosterone undecanoateCytochrome P450 2B6enzyme
DB13946Testosterone undecanoateCytochrome P450 2C19enzyme
DB13946Testosterone undecanoateCytochrome P450 2C8enzyme
DB13946Testosterone undecanoateCytochrome P450 2C9enzyme
DB13946Testosterone undecanoateCytochrome P450 3A43enzyme
DB13946Testosterone undecanoate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
DB13946Testosterone undecanoateAndrogen receptortarget
DB13946Testosterone undecanoateEstrogen receptor alphatarget
DB13946Testosterone undecanoateMineralocorticoid receptortarget
DB13946Testosterone undecanoateSolute carrier organic anion transporter family member 1A2transporter
DB13946Testosterone undecanoateSolute carrier family 22 member 8transporter
DB13946Testosterone undecanoateSolute carrier family 22 member 7transporter
DB13946Testosterone undecanoateMultidrug resistance protein 1transporter
DB13946Testosterone undecanoateSodium/bile acid cotransportertransporter
DB13946Testosterone undecanoateSolute carrier family 22 member 3transporter
DB13946Testosterone undecanoateSolute carrier family 22 member 4transporter
DB13946Testosterone undecanoateATP-binding cassette sub-family G member 2transporter
DB13952Estradiol acetateSex hormone-binding globulincarrier
DB13952Estradiol acetateSerum albumincarrier
DB13952Estradiol acetateFatty acid-binding protein, intestinalcarrier
DB13952Estradiol acetateCytochrome P450 1A2enzyme
DB13952Estradiol acetateUDP-glucuronosyltransferase 1-1enzyme
DB13952Estradiol acetateCytochrome P450 3A4enzyme
DB13952Estradiol acetateCytochrome P450 3A5enzyme
DB13952Estradiol acetateCytochrome P450 3A7enzyme
DB13952Estradiol acetateCytochrome P450 1A1enzyme
DB13952Estradiol acetateCytochrome P450 1B1enzyme
DB13952Estradiol acetateCytochrome P450 2C19enzyme
DB13952Estradiol acetateCytochrome P450 2C8enzyme
DB13952Estradiol acetateCytochrome P450 2C9enzyme
DB13952Estradiol acetateEstrogen receptor alphatarget
DB13952Estradiol acetateNuclear receptor subfamily 1 group I member 2target
DB13952Estradiol acetateEstrogen receptor betatarget
DB13952Estradiol acetateNeuronal acetylcholine receptor subunit alpha-4target
DB13952Estradiol acetateNuclear receptor coactivator 2target
DB13952Estradiol acetateG-protein coupled estrogen receptor 1target
DB13952Estradiol acetateATP synthase subunit atarget
DB13952Estradiol acetateBeclin-1target
DB13952Estradiol acetateEstradiol 17-beta-dehydrogenase 2target
DB13952Estradiol acetateEstrogen-related receptor gammatarget
DB13952Estradiol acetateSolute carrier family 22 member 2transporter
DB13952Estradiol acetateSolute carrier family 22 member 1transporter
DB13952Estradiol acetateSolute carrier family 22 member 3transporter
DB13952Estradiol acetateSolute carrier organic anion transporter family member 2B1transporter
DB13952Estradiol acetateSolute carrier organic anion transporter family member 1A2transporter
DB13952Estradiol acetateMultidrug resistance-associated protein 7transporter
DB13952Estradiol acetateSolute carrier family 22 member 11transporter
DB13952Estradiol acetateATP-binding cassette sub-family G member 2transporter
DB13952Estradiol acetateSolute carrier organic anion transporter family member 1B1transporter
DB13952Estradiol acetateMultidrug resistance protein 1transporter
DB13952Estradiol acetateSolute carrier family 22 member 8transporter
DB13952Estradiol acetateSolute carrier organic anion transporter family member 1B3transporter
DB13952Estradiol acetateSolute carrier organic anion transporter family member 1C1transporter
DB13952Estradiol acetateSolute carrier organic anion transporter family member 4A1transporter
DB13953Estradiol benzoateSex hormone-binding globulincarrier
DB13953Estradiol benzoateSerum albumincarrier
DB13953Estradiol benzoateFatty acid-binding protein, intestinalcarrier
DB13953Estradiol benzoateCytochrome P450 1A2enzyme
DB13953Estradiol benzoateUDP-glucuronosyltransferase 1-1enzyme
DB13953Estradiol benzoateCytochrome P450 3A4enzyme
DB13953Estradiol benzoateCytochrome P450 3A5enzyme
DB13953Estradiol benzoateCytochrome P450 3A7enzyme
DB13953Estradiol benzoateCytochrome P450 1A1enzyme
DB13953Estradiol benzoateCytochrome P450 1B1enzyme
DB13953Estradiol benzoateCytochrome P450 2C19enzyme
DB13953Estradiol benzoateCytochrome P450 2C8enzyme
DB13953Estradiol benzoateCytochrome P450 2C9enzyme
DB13953Estradiol benzoateEstrogen receptor alphatarget
DB13953Estradiol benzoateNuclear receptor subfamily 1 group I member 2target
DB13953Estradiol benzoateEstrogen receptor betatarget
DB13953Estradiol benzoateNeuronal acetylcholine receptor subunit alpha-4target
DB13953Estradiol benzoateNuclear receptor coactivator 2target
DB13953Estradiol benzoateG-protein coupled estrogen receptor 1target
DB13953Estradiol benzoateATP synthase subunit atarget
DB13953Estradiol benzoateBeclin-1target
DB13953Estradiol benzoateEstradiol 17-beta-dehydrogenase 2target
DB13953Estradiol benzoateEstrogen-related receptor gammatarget
DB13953Estradiol benzoateSolute carrier family 22 member 2transporter
DB13953Estradiol benzoateSolute carrier family 22 member 1transporter
DB13953Estradiol benzoateSolute carrier family 22 member 3transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 2B1transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1A2transporter
DB13953Estradiol benzoateMultidrug resistance-associated protein 7transporter
DB13953Estradiol benzoateSolute carrier family 22 member 11transporter
DB13953Estradiol benzoateATP-binding cassette sub-family G member 2transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1B1transporter
DB13953Estradiol benzoateMultidrug resistance protein 1transporter
DB13953Estradiol benzoateSolute carrier family 22 member 8transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1B3transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1C1transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 4A1transporter
DB13954Estradiol cypionateSex hormone-binding globulincarrier
DB13954Estradiol cypionateSerum albumincarrier
DB13954Estradiol cypionateFatty acid-binding protein, intestinalcarrier
DB13954Estradiol cypionateCytochrome P450 1A2enzyme
DB13954Estradiol cypionateUDP-glucuronosyltransferase 1-1enzyme
DB13954Estradiol cypionateCytochrome P450 3A4enzyme
DB13954Estradiol cypionateCytochrome P450 3A5enzyme
DB13954Estradiol cypionateCytochrome P450 3A7enzyme
DB13954Estradiol cypionateCytochrome P450 1A1enzyme
DB13954Estradiol cypionateCytochrome P450 1B1enzyme
DB13954Estradiol cypionateCytochrome P450 2C19enzyme
DB13954Estradiol cypionateCytochrome P450 2C8enzyme
DB13954Estradiol cypionateCytochrome P450 2C9enzyme
DB13954Estradiol cypionateEstrogen receptor alphatarget
DB13954Estradiol cypionateNuclear receptor subfamily 1 group I member 2target
DB13954Estradiol cypionateEstrogen receptor betatarget
DB13954Estradiol cypionateNeuronal acetylcholine receptor subunit alpha-4target
DB13954Estradiol cypionateNuclear receptor coactivator 2target
DB13954Estradiol cypionateG-protein coupled estrogen receptor 1target
DB13954Estradiol cypionateATP synthase subunit atarget
DB13954Estradiol cypionateBeclin-1target
DB13954Estradiol cypionateEstradiol 17-beta-dehydrogenase 2target
DB13954Estradiol cypionateEstrogen-related receptor gammatarget
DB13954Estradiol cypionateSolute carrier family 22 member 2transporter
DB13954Estradiol cypionateSolute carrier family 22 member 1transporter
DB13954Estradiol cypionateSolute carrier family 22 member 3transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 2B1transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1A2transporter
DB13954Estradiol cypionateMultidrug resistance-associated protein 7transporter
DB13954Estradiol cypionateSolute carrier family 22 member 11transporter
DB13954Estradiol cypionateATP-binding cassette sub-family G member 2transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1B1transporter
DB13954Estradiol cypionateMultidrug resistance protein 1transporter
DB13954Estradiol cypionateSolute carrier family 22 member 8transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1B3transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1C1transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 4A1transporter
DB13955Estradiol dienanthateSex hormone-binding globulincarrier
DB13955Estradiol dienanthateSerum albumincarrier
DB13955Estradiol dienanthateFatty acid-binding protein, intestinalcarrier
DB13955Estradiol dienanthateCytochrome P450 1A2enzyme
DB13955Estradiol dienanthateUDP-glucuronosyltransferase 1-1enzyme
DB13955Estradiol dienanthateCytochrome P450 3A4enzyme
DB13955Estradiol dienanthateCytochrome P450 3A5enzyme
DB13955Estradiol dienanthateCytochrome P450 3A7enzyme
DB13955Estradiol dienanthateCytochrome P450 1A1enzyme
DB13955Estradiol dienanthateCytochrome P450 1B1enzyme
DB13955Estradiol dienanthateCytochrome P450 2C19enzyme
DB13955Estradiol dienanthateCytochrome P450 2C8enzyme
DB13955Estradiol dienanthateCytochrome P450 2C9enzyme
DB13955Estradiol dienanthateEstrogen receptor alphatarget
DB13955Estradiol dienanthateNuclear receptor subfamily 1 group I member 2target
DB13955Estradiol dienanthateEstrogen receptor betatarget
DB13955Estradiol dienanthateNeuronal acetylcholine receptor subunit alpha-4target
DB13955Estradiol dienanthateNuclear receptor coactivator 2target
DB13955Estradiol dienanthateG-protein coupled estrogen receptor 1target
DB13955Estradiol dienanthateATP synthase subunit atarget
DB13955Estradiol dienanthateBeclin-1target
DB13955Estradiol dienanthateEstradiol 17-beta-dehydrogenase 2target
DB13955Estradiol dienanthateEstrogen-related receptor gammatarget
DB13955Estradiol dienanthateSolute carrier family 22 member 2transporter
DB13955Estradiol dienanthateSolute carrier family 22 member 1transporter
DB13955Estradiol dienanthateSolute carrier family 22 member 3transporter
DB13955Estradiol dienanthateSolute carrier organic anion transporter family member 2B1transporter
DB13955Estradiol dienanthateSolute carrier organic anion transporter family member 1A2transporter
DB13955Estradiol dienanthateMultidrug resistance-associated protein 7transporter
DB13955Estradiol dienanthateSolute carrier family 22 member 11transporter
DB13955Estradiol dienanthateATP-binding cassette sub-family G member 2transporter
DB13955Estradiol dienanthateSolute carrier organic anion transporter family member 1B1transporter
DB13955Estradiol dienanthateMultidrug resistance protein 1transporter
DB13955Estradiol dienanthateSolute carrier family 22 member 8transporter
DB13955Estradiol dienanthateSolute carrier organic anion transporter family member 1B3transporter
DB13955Estradiol dienanthateSolute carrier organic anion transporter family member 1C1transporter
DB13955Estradiol dienanthateSolute carrier organic anion transporter family member 4A1transporter
DB13956Estradiol valerateSex hormone-binding globulincarrier
DB13956Estradiol valerateSerum albumincarrier
DB13956Estradiol valerateFatty acid-binding protein, intestinalcarrier
DB13956Estradiol valerateCytochrome P450 1A2enzyme
DB13956Estradiol valerateUDP-glucuronosyltransferase 1-1enzyme
DB13956Estradiol valerateCytochrome P450 3A4enzyme
DB13956Estradiol valerateCytochrome P450 3A5enzyme
DB13956Estradiol valerateCytochrome P450 3A7enzyme
DB13956Estradiol valerateCytochrome P450 1A1enzyme
DB13956Estradiol valerateCytochrome P450 1B1enzyme
DB13956Estradiol valerateCytochrome P450 2C19enzyme
DB13956Estradiol valerateCytochrome P450 2C8enzyme
DB13956Estradiol valerateCytochrome P450 2C9enzyme
DB13956Estradiol valerateEstrogen receptor alphatarget
DB13956Estradiol valerateNuclear receptor subfamily 1 group I member 2target
DB13956Estradiol valerateEstrogen receptor betatarget
DB13956Estradiol valerateNeuronal acetylcholine receptor subunit alpha-4target
DB13956Estradiol valerateNuclear receptor coactivator 2target
DB13956Estradiol valerateG-protein coupled estrogen receptor 1target
DB13956Estradiol valerateATP synthase subunit atarget
DB13956Estradiol valerateBeclin-1target
DB13956Estradiol valerateEstradiol 17-beta-dehydrogenase 2target
DB13956Estradiol valerateEstrogen-related receptor gammatarget
DB13956Estradiol valerateSolute carrier family 22 member 2transporter
DB13956Estradiol valerateSolute carrier family 22 member 1transporter
DB13956Estradiol valerateSolute carrier family 22 member 3transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 2B1transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1A2transporter
DB13956Estradiol valerateMultidrug resistance-associated protein 7transporter
DB13956Estradiol valerateSolute carrier family 22 member 11transporter
DB13956Estradiol valerateATP-binding cassette sub-family G member 2transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1B1transporter
DB13956Estradiol valerateMultidrug resistance protein 1transporter
DB13956Estradiol valerateSolute carrier family 22 member 8transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1B3transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1C1transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 4A1transporter
DB09231BenidipineCytochrome P450 3A4enzyme
DB09231BenidipineCytochrome P450 3A5enzyme
DB09231BenidipineVoltage dependent L type calcium channeltarget
DB09231BenidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB09231BenidipineVoltage-dependent T-type calcium channeltarget
DB11633IsavuconazoleCytochrome P450 3A4enzyme
DB11633IsavuconazoleCytochrome P450 3A5enzyme
DB11633IsavuconazoleCytochrome P450 2C8enzyme
DB11633IsavuconazoleCytochrome P450 2C9enzyme
DB11633IsavuconazoleCytochrome P450 2C19enzyme
DB11633IsavuconazoleCytochrome P450 2D6enzyme
DB11633IsavuconazoleCytochrome P450 2B6enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
DB11633IsavuconazoleLanosterol 14-alpha demethylasetarget
DB11633IsavuconazolePotassium voltage-gated channel subfamily H member 2target
DB11633IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 2target
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 3target
DB11633IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
DB11633IsavuconazolePotassium voltage-gated channel subfamily A member 5target
DB11633IsavuconazolePotassium voltage-gated channel subfamily D member 3target
DB11633IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
DB11633IsavuconazoleSodium channel protein type 5 subunit alphatarget
DB11633IsavuconazoleMultidrug resistance protein 1transporter
DB11633IsavuconazoleATP-binding cassette sub-family G member 2transporter
DB11633IsavuconazoleSolute carrier family 22 member 2transporter
DB11712TezacaftorSerum albumincarrier
DB11712TezacaftorCytochrome P450 3A4enzyme
DB11712TezacaftorCytochrome P450 3A5enzyme
DB11712TezacaftorCystic fibrosis transmembrane conductance regulatortarget
DB11586AsunaprevirMultidrug resistance protein 1carrier
DB11586AsunaprevirSolute carrier organic anion transporter family member 1B1carrier
DB11586AsunaprevirSolute carrier organic anion transporter family member 2B1carrier
DB11586AsunaprevirCYP3Aenzyme
DB11586AsunaprevirCytochrome P450 3A4enzyme
DB11586AsunaprevirCytochrome P450 3A5enzyme
DB11586AsunaprevirCytochrome P450 2A6enzyme
DB11586AsunaprevirCytochrome P450 2B6enzyme
DB11586AsunaprevirCytochrome P450 2C9enzyme
DB11586AsunaprevirCytochrome P450 2C19enzyme
DB11586AsunaprevirCytochrome P450 2D6enzyme
DB11586AsunaprevirHepatitis C virus NS3 protease/helicasetarget
DB11586AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
DB11586AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
DB11586AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilCytochrome P450 3A5enzyme
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB05521TelaprevirSerum albumincarrier
DB05521TelaprevirAlpha-1-acid glycoprotein 1carrier
DB05521TelaprevirCytochrome P450 3A4enzyme
DB05521TelaprevirCytochrome P450 3A5enzyme
DB05521TelaprevirNS3/4A proteintarget
DB05521TelaprevirSolute carrier organic anion transporter family member 1B1target
DB05521TelaprevirSolute carrier organic anion transporter family member 2B1target
DB05521TelaprevirMultidrug resistance protein 1transporter
DB14185Aripiprazole lauroxilSerum albumincarrier
DB14185Aripiprazole lauroxilCytochrome P450 3A4enzyme
DB14185Aripiprazole lauroxilCytochrome P450 2D6enzyme
DB14185Aripiprazole lauroxilCytochrome P450 3A5enzyme
DB14185Aripiprazole lauroxilCytochrome P450 3A7enzyme
DB14185Aripiprazole lauroxilD(2) dopamine receptortarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Atarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 2Atarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Btarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Dtarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 1Etarget
DB14185Aripiprazole lauroxilD(1A) dopamine receptortarget
DB14185Aripiprazole lauroxilD(1B) dopamine receptortarget
DB14185Aripiprazole lauroxilD(3) dopamine receptortarget
DB14185Aripiprazole lauroxilD(4) dopamine receptortarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 2Ctarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 3Atarget
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 6target
DB14185Aripiprazole lauroxil5-hydroxytryptamine receptor 7target
DB14185Aripiprazole lauroxilHistamine H1 receptortarget
DB14185Aripiprazole lauroxilAlpha-1A adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-1B adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-2A adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-2B adrenergic receptortarget
DB14185Aripiprazole lauroxilAlpha-2C adrenergic receptortarget
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M1target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M2target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M3target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M4target
DB14185Aripiprazole lauroxilMuscarinic acetylcholine receptor M5target
DB09256TegafurCytochrome P450 2A6enzyme
DB09256TegafurCytochrome P450 1A2enzyme
DB09256TegafurCytochrome P450 2C8enzyme
DB09256TegafurCytochrome P450 2E1enzyme
DB09256TegafurCytochrome P450 3A5enzyme
DB09256TegafurThymidylate synthasetarget
DB12301DoravirineCytochrome P450 3A4enzyme
DB12301DoravirineCytochrome P450 3A5enzyme
DB12301DoravirineReverse transcriptase/RNaseHtarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineCytochrome P450 3A7enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineSodium channel protein type 5 subunit alphatarget
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNeuronal acetylcholine receptor subunit beta-2target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineMultidrug resistance protein 1transporter
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB08899EnzalutamideSerum albumincarrier
DB08899EnzalutamideCytochrome P450 2C8enzyme
DB08899EnzalutamideCytochrome P450 3A4enzyme
DB08899EnzalutamideCytochrome P450 2C9enzyme
DB08899EnzalutamideCytochrome P450 2C19enzyme
DB08899EnzalutamideCytochrome P450 2B6enzyme
DB08899EnzalutamideCytochrome P450 2D6enzyme
DB08899EnzalutamideCytochrome P450 3A5enzyme
DB08899EnzalutamideAndrogen receptortarget
DB08899EnzalutamideMultidrug resistance protein 1transporter
DB00313Valproic AcidSerum albumincarrier
DB00313Valproic AcidCytochrome P450 2A6enzyme
DB00313Valproic AcidCytochrome P450 2B6enzyme
DB00313Valproic AcidCytochrome P450 2C9enzyme
DB00313Valproic AcidCytochrome P450 3A5enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-9enzyme
DB00313Valproic AcidProstaglandin G/H synthase 1enzyme
DB00313Valproic AcidCytochrome P450 1A2enzyme
DB00313Valproic AcidCytochrome P450 2C18enzyme
DB00313Valproic AcidCytochrome P450 2C19enzyme
DB00313Valproic AcidCytochrome P450 2C8enzyme
DB00313Valproic AcidCytochrome P450 3A4enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-4enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-8enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-10enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-6enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-3enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 2B7enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 2B15enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-1enzyme
DB00313Valproic Acid4-aminobutyrate aminotransferase, mitochondrialtarget
DB00313Valproic AcidHistone deacetylase 9target
DB00313Valproic AcidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
DB00313Valproic Acid2-oxoglutarate dehydrogenase, mitochondrialtarget
DB00313Valproic AcidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
DB00313Valproic AcidSodium channel proteintarget
DB00313Valproic AcidHistone deacetylase 2target
DB00313Valproic AcidPeroxisome proliferator-activated receptor alphatarget
DB00313Valproic AcidPeroxisome proliferator-activated receptor deltatarget
DB00313Valproic AcidPeroxisome proliferator-activated receptor gammatarget
DB00313Valproic AcidSolute carrier family 22 member 5transporter
DB00313Valproic AcidSolute carrier family 22 member 6transporter
DB00313Valproic AcidSolute carrier family 22 member 8transporter
DB00313Valproic AcidMonocarboxylate transporter 1transporter
DB00313Valproic AcidSolute carrier family 22 member 7transporter
DB00313Valproic AcidSolute carrier organic anion transporter family member 2B1transporter
DB00738PentamidineCytochrome P450 2C19enzyme
DB00738PentamidineCytochrome P450 2C8enzyme
DB00738PentamidineCytochrome P450 2D6enzyme
DB00738PentamidineCytochrome P450 1A1enzyme
DB00738PentamidineCytochrome P450 3A5enzyme
DB00738PentamidineCytochrome P450 4A11enzyme
DB00738PentamidineDNAtarget
DB00738PentamidinetRNA (cytosine(38)-C(5))-methyltransferasetarget
DB12130LorlatinibCytochrome p450 3A subfamilyenzyme
DB12130LorlatinibCytochrome P450 3A5enzyme
DB12130LorlatinibCytochrome P450 2B6enzyme
DB12130LorlatinibCytochrome P450 2C8enzyme
DB12130LorlatinibCytochrome P450 2C19enzyme
DB12130LorlatinibUDP-glucuronosyltransferase 1-3enzyme
DB12130LorlatinibALK tyrosine kinase receptortarget