Cervical Cancers

Also known as: Cervical Cancer / Ca cervix / Cervical carcinoma NOS / Ca cervix uteri NOS / Carcinoma uterine cerix / Cervix uteri cancer / Cervix carcinoma / Carcinoma cervix / Carcinoma uterine cervix / Cancer of the Uterine Cervix

DrugDrug NameDrug Description
DB00290BleomycinA complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
DB00515CisplatinCisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
DB01181IfosfamideIfosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppresive agent.
DB00305MitomycinAn antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional alkylating agents causing cross-linking of DNA and inhibition of DNA synthesis. [PubChem]
DB09037PembrolizumabPembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptor. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype with the containing a stabilizing S228P Fc mutation.[A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds.[F136] It was developed by Merck & Co and firstly approved for the treatment of metastatic malignant melanoma. This is the first approved therapy against PD-1.[A7624] It was approved firstly by the FDA on September 4, 2014.[L2954] Its approval in melanoma was extended to several countries such as Australia, Israel, Korea, Macau, the European Union and the United Arab Emirates.[A33350] On June 12, 2018, Pembrolizumab was approved for the treatment of cervical cancer under the status of accelerated approval.[L2955]
DrugDrug NameTargetType
DB00290BleomycinDNA ligase 3target
DB00290BleomycinDNA ligase 1target
DB00290BleomycinDNAtarget
DB00290BleomycinBleomycin hydrolaseenzyme
DB00515CisplatinDNAtarget
DB00515CisplatinCanalicular multispecific organic anion transporter 2transporter
DB00515CisplatinMultidrug resistance-associated protein 5transporter
DB00515CisplatinCanalicular multispecific organic anion transporter 1transporter
DB00515CisplatinSolute carrier family 22 member 2transporter
DB00515CisplatinHigh affinity copper uptake protein 1transporter
DB00515CisplatinProbable low affinity copper uptake protein 2transporter
DB00515CisplatinMultidrug resistance-associated protein 6transporter
DB00515CisplatinMultidrug resistance protein 1transporter
DB00515CisplatinCopper-transporting ATPase 2transporter
DB00515CisplatinCopper-transporting ATPase 1transporter
DB00515CisplatinProstaglandin G/H synthase 2enzyme
DB00515CisplatinMyeloperoxidaseenzyme
DB00515CisplatinXanthine dehydrogenase/oxidaseenzyme
DB00515CisplatinArylamine N-acetyltransferaseenzyme
DB00515CisplatinCytochrome P450 2C9enzyme
DB00515CisplatinCytochrome P450 2B6enzyme
DB00515CisplatinCholinesteraseenzyme
DB00515CisplatinCytochrome P450 4A11enzyme
DB00515CisplatinATP-binding cassette sub-family G member 2transporter
DB00515CisplatinGlutathione S-transferase theta-1enzyme
DB00515CisplatinMetallothionein-1Aenzyme
DB00515CisplatinMetallothionein-2enzyme
DB00515CisplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00515CisplatinGlutathione S-transferase Penzyme
DB00515CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00515CisplatinGlutathione S-transferase Mu 1enzyme
DB00515CisplatinDNA-3-methyladenine glycosylasetarget
DB00515CisplatinAlpha-2-macroglobulintarget
DB00515CisplatinSerum albumincarrier
DB00515CisplatinSerotransferrintarget
DB00515CisplatinCopper transport protein ATOX1target
DB01181IfosfamideCytochrome P450 2B6enzyme
DB01181IfosfamideDNAtarget
DB01181IfosfamideCytochrome P450 3A4enzyme
DB01181IfosfamideCytochrome P450 3A5enzyme
DB01181IfosfamideCytochrome P450 2C9enzyme
DB01181IfosfamideCytochrome P450 2C8enzyme
DB01181IfosfamideCytochrome P450 2A6enzyme
DB01181IfosfamideCytochrome P450 2C19enzyme
DB01181IfosfamideCytochrome P450 2C18enzyme
DB01181IfosfamideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideNuclear receptor subfamily 1 group I member 2target
DB00305MitomycinDNAtarget
DB00305MitomycinNADPH--cytochrome P450 reductaseenzyme
DB09037PembrolizumabProgrammed cell death protein 1target
DrugDrug NamePhaseStatusCount
DB03166Acetic acid0Active Not Recruiting1
DB00295Morphine0Completed1
DB01123Proflavine0Active Not Recruiting1
DB12218AZD-53631Active Not Recruiting1
DB01143Amifostine1Withdrawn1
DB11595Atezolizumab1Recruiting1
DB00136Calcitriol1Active Not Recruiting1
DB01101Capecitabine1Withdrawn1
DB00958Carboplatin1Completed2
DB00958Carboplatin1Terminated1
DB00958Carboplatin1Unknown Status1
DB12033Cediranib1Active Not Recruiting1
DB00369Cidofovir1Completed1
DB00369Cidofovir1Unknown Status1
DB00515Cisplatin1Completed5
DB00515Cisplatin1Recruiting1
DB00515Cisplatin1Withdrawn3
DB01248Docetaxel1Completed2
DB01248Docetaxel1Terminated1
DB11714Durvalumab1Active Not Recruiting1
DB11714Durvalumab1Recruiting1
DB00530Erlotinib1Withdrawn1
DB01590Everolimus1Withdrawn1
DB10300Human papillomavirus type 11 L1 capsid protein antigen1Completed1
DB00724Imiquimod1Recruiting1
DB09374Indocyanine green acid form1Recruiting2
DB00125L-Arginine1Withdrawn1
DB05296Motexafin lutetium1Terminated1
DB00220Nelfinavir1Completed1
DB09035Nivolumab1Recruiting1
DB09074Olaparib1Completed1
DB01229Paclitaxel1Completed2
DB01229Paclitaxel1Unknown Status1
DB09037Pembrolizumab1Recruiting2
DB00642Pemetrexed1Completed1
DB13128Sizofiran1Recruiting1
DB06287Temsirolimus1Active Not Recruiting1
DB13944Testosterone enanthate1Completed1
DB04858Tirapazamine1Completed1
DB01030Topotecan1Completed4
DB11771Tremelimumab1Active Not Recruiting1
DB11771Tremelimumab1Recruiting1
DB04879Vatalanib1Completed1
DB00361Vinorelbine1Completed1
DB09145Water1Recruiting2
DB00399Zoledronic acid1Terminated1
DB00041Aldesleukin1 / 2Recruiting2
DB00041Aldesleukin1 / 2Terminated2
DB01143Amifostine1 / 2Completed1
DB01217Anastrozole1 / 2Active Not Recruiting1
DB11885Anlotinib1 / 2Recruiting1
DB11595Atezolizumab1 / 2Recruiting1
DB00112Bevacizumab1 / 2Recruiting1
DB00958Carboplatin1 / 2Active Not Recruiting1
DB00958Carboplatin1 / 2Completed2
DB00958Carboplatin1 / 2Recruiting1
DB00482Celecoxib1 / 2Completed1
DB00515Cisplatin1 / 2Active Not Recruiting1
DB00515Cisplatin1 / 2Completed3
DB00515Cisplatin1 / 2Recruiting1
DB00515Cisplatin1 / 2Terminated1
DB00531Cyclophosphamide1 / 2Recruiting2
DB00531Cyclophosphamide1 / 2Terminated1
DB01248Docetaxel1 / 2Withdrawn1
DB11714Durvalumab1 / 2Recruiting1
DB11714Durvalumab1 / 2Suspended1
DB01073Fludarabine1 / 2Recruiting2
DB01073Fludarabine1 / 2Terminated2
DB00544Fluorouracil1 / 2Completed1
DB11740MK-17751 / 2Terminated1
DB09035Nivolumab1 / 2Recruiting1
DB01229Paclitaxel1 / 2Active Not Recruiting1
DB01229Paclitaxel1 / 2Completed1
DB09037Pembrolizumab1 / 2Recruiting2
DB12893Sacituzumab govitecan1 / 2Active Not Recruiting1
DB01030Topotecan1 / 2Completed1
DB01030Topotecan1 / 2Terminated1
DB00945Acetylsalicylic acid2Recruiting1
DB00041Aldesleukin2Completed3
DB01370Aluminium2Not Yet Recruiting1
DB01143Amifostine2Terminated1
DB01169Arsenic trioxide2Completed1
DB00126Ascorbic acid2Completed1
DB11595Atezolizumab2Active Not Recruiting1
DB11595Atezolizumab2Not Yet Recruiting1
DB11595Atezolizumab2Recruiting3
DB11945Avelumab2Recruiting1
DB12459Belotecan2Completed1
DB00112Bevacizumab2Completed3
DB00112Bevacizumab2Recruiting3
DB00112Bevacizumab2Terminated1
DB00112Bevacizumab2Withdrawn1
DB00188Bortezomib2Terminated1
DB11865Brivanib alaninate2Completed1
DB11752Bryostatin 12Completed1
DB01156Bupropion2Completed1
DB12476CPG-528522Completed1
DB01101Capecitabine2Completed2
DB00958Carboplatin2Active Not Recruiting2
DB00958Carboplatin2Completed4
DB00958Carboplatin2Recruiting2
DB00958Carboplatin2Unknown Status1
DB00958Carboplatin2Withdrawn1
DB04849Cediranib2Completed1
DB00482Celecoxib2Completed1
DB00002Cetuximab2Active Not Recruiting1
DB00002Cetuximab2Completed2
DB00091Ciclosporin2Completed1
DB00515Cisplatin2Completed12
DB00515Cisplatin2Recruiting6
DB00515Cisplatin2Terminated3
DB00515Cisplatin2Unknown Status5
DB00515Cisplatin2Withdrawn2
DB00531Cyclophosphamide2Completed2
DB00531Cyclophosphamide2Recruiting1
DB01248Docetaxel2Completed2
DB00997Doxorubicin2Recruiting1
DB11714Durvalumab2Enrolling by Invitation1
DB06243Eflornithine2Completed1
DB00153Ergocalciferol2Recruiting1
DB00773Etoposide2Terminated1
DB12185Exatecan2Completed1
DB11741Famitinib2Recruiting1
DB00099Filgrastim2Completed1
DB01073Fludarabine2Completed3
DB00544Fluorouracil2Unknown Status1
DB00569Fondaparinux2Completed1
DB00317Gefitinib2Completed1
DB00441Gemcitabine2Completed1
DB00441Gemcitabine2Terminated2
DB11627Hepatitis B Vaccine (Recombinant)2Completed1
DB10300Human papillomavirus type 11 L1 capsid protein antigen2Completed1
DB01275Hydralazine2Completed1
DB00724Imiquimod2Completed1
DB00762Irinotecan2Terminated1
DB11733Irofulven2Completed1
DB00982Isotretinoin2Completed1
DB00982Isotretinoin2Terminated1
DB00125L-Arginine2Completed1
DB00448Lansoprazole2Recruiting1
DB00703Methazolamide2Withdrawn1
DB12117Mitometh2Withdrawn1
DB00745Modafinil2Active Not Recruiting1
DB00745Modafinil2Enrolling by Invitation1
DB00688Mycophenolate mofetil2Completed1
DB13145Nedaplatin2Recruiting1
DB06192Nimotuzumab2Active Not Recruiting1
DB06192Nimotuzumab2Recruiting1
DB09035Nivolumab2Recruiting2
DB00526Oxaliplatin2Completed1
DB01229Paclitaxel2Active Not Recruiting2
DB01229Paclitaxel2Completed6
DB01229Paclitaxel2Recruiting4
DB01229Paclitaxel2Terminated3
DB01229Paclitaxel2Unknown Status2
DB01269Panitumumab2Unknown Status1
DB06589Pazopanib2Terminated1
DB06589Pazopanib2Withdrawn1
DB09037Pembrolizumab2Recruiting4
DB00642Pemetrexed2Completed2
DB12332Rucaparib2Not Yet Recruiting1
DB12332Rucaparib2Recruiting1
DB00020Sargramostim2Completed1
DB06436Semaxanib2Completed1
DB04858Tirapazamine2Completed1
DB01030Topotecan2Completed5
DB01030Topotecan2Withdrawn1
DB08911Trametinib2Terminated1
DB11969Uprosertib2Terminated1
DB04959Verpasep caltespen2Completed3
DB00361Vinorelbine2Completed1
DB11094Vitamin D2Recruiting1
DB00515Cisplatin2 / 3Recruiting1
DB01234Dexamethasone2 / 3Recruiting1
DB14019Fosnetupitant2 / 3Recruiting1
DB10994Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen2 / 3Completed1
DB00377Palonosetron2 / 3Recruiting1
DB00316Acetaminophen3Recruiting1
DB00945Acetylsalicylic acid3Recruiting1
DB01060Amoxicillin3Recruiting1
DB00112Bevacizumab3Not Yet Recruiting1
DB00112Bevacizumab3Recruiting1
DB00290Bleomycin3Completed1
DB00958Carboplatin3Not Yet Recruiting2
DB00958Carboplatin3Recruiting3
DB00958Carboplatin3Terminated1
DB01114Chlorphenamine3Recruiting1
DB00477Chlorpromazine3Recruiting1
DB00515Cisplatin3Active Not Recruiting2
DB00515Cisplatin3Completed6
DB00515Cisplatin3Not Yet Recruiting2
DB00515Cisplatin3Recruiting11
DB00515Cisplatin3Terminated3
DB00515Cisplatin3Unknown Status1
DB00515Cisplatin3Withdrawn1
DB06779Dalteparin3Completed1
DB00514Dextromethorphan3Recruiting1
DB01248Docetaxel3Recruiting1
DB05076Fenretinide3Completed1
DB00544Fluorouracil3Completed2
DB00441Gemcitabine3Recruiting1
DB00441Gemcitabine3Unknown Status1
DB00441Gemcitabine3Withdrawn1
DB10300Human papillomavirus type 11 L1 capsid protein antigen3Completed3
DB10300Human papillomavirus type 11 L1 capsid protein antigen3Recruiting1
DB10994Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen3Completed1
DB10994Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen3Recruiting1
DB01275Hydralazine3Not Yet Recruiting1
DB01181Ifosfamide3Completed1
DB01181Ifosfamide3Not Yet Recruiting1
DB01378Magnesium cation3Not Yet Recruiting1
DB00563Methotrexate3Completed1
DB00305Mitomycin3Completed1
DB06192Nimotuzumab3Active Not Recruiting1
DB09496Octinoxate3Recruiting1
DB00104Octreotide3Completed1
DB01428Oxybenzone3Recruiting1
DB09140Oxygen3Recruiting1
DB01229Paclitaxel3Active Not Recruiting1
DB01229Paclitaxel3Not Yet Recruiting3
DB01229Paclitaxel3Recruiting6
DB01229Paclitaxel3Withdrawn1
DB09037Pembrolizumab3Recruiting1
DB00388Phenylephrine3Recruiting1
DB09536Titanium dioxide3Recruiting1
DB01030Topotecan3Completed1
DB08604Triclosan3Recruiting1
DB00570Vinblastine3Completed1
DB00541Vincristine3Completed1
DB00309Vindesine3Completed1
DB01156Bupropion4Completed1
DB00515Cisplatin4Completed1
DB00016Erythropoietin4Completed1
DB09222Fibrinogen Human4Active Not Recruiting1
DB13146Fluciclovine (18F)4Recruiting1
DB11571Human Thrombin4Active Not Recruiting1
DB10300Human papillomavirus type 11 L1 capsid protein antigen4Active Not Recruiting1
DB10300Human papillomavirus type 11 L1 capsid protein antigen4Completed1
DB10300Human papillomavirus type 11 L1 capsid protein antigen4Unknown Status1
DB10994Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen4Completed2
DB10994Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen4Recruiting1
DB10299Human papillomavirus type 6 L1 capsid protein antigen4Recruiting1
DB00184Nicotine4Completed1
DB03166Acetic acidNot AvailableActive Not Recruiting1
DB11945AvelumabNot AvailableNot Yet Recruiting1
DB06626AxitinibNot AvailableNot Yet Recruiting1
DB00515CisplatinNot AvailableActive Not Recruiting2
DB00515CisplatinNot AvailableRecruiting3
DB01189DesfluraneNot AvailableCompleted1
DB00997DoxorubicinNot AvailableRecruiting2
DB00813FentanylNot AvailableCompleted1
DB00544FluorouracilNot AvailableCompleted1
DB00544FluorouracilNot AvailableRecruiting1
DB10300Human papillomavirus type 11 L1 capsid protein antigenNot AvailableActive Not Recruiting1
DB10300Human papillomavirus type 11 L1 capsid protein antigenNot AvailableCompleted1
DB00327HydromorphoneNot AvailableCompleted1
DB00762IrinotecanNot AvailableUnknown Status1
DB00305MitomycinNot AvailableRecruiting1
DB00745ModafinilNot AvailableAvailable1
DB00184NicotineNot AvailableCompleted1
DB00184NicotineNot AvailableRecruiting1
DB01123ProflavineNot AvailableActive Not Recruiting1
DB00571PropranololNot AvailableActive Not Recruiting1
DB00899RemifentanilNot AvailableCompleted1
DB00296RopivacaineNot AvailableCompleted1
DB00755TretinoinNot AvailableCompleted1
DB01273VareniclineNot AvailableCompleted1