Epilepsies

Also known as: Epilepsy / (Epilepsy) or (epileptic attack) / Epilepsy, unspecified / Epileptic fit / Epilepsy NOS / Epileptic seizure

DrugDrug NameDrug Description
DB00349ClobazamA benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.
DB00996GabapentinAn anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
DB01202LevetiracetamA novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy.
DB00909ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
DrugDrug NameTargetType
DB00349ClobazamCytochrome P450 2C19enzyme
DB00349ClobazamCytochrome P450 3A4enzyme
DB00349ClobazamCytochrome P450 2B6enzyme
DB00349ClobazamCytochrome P450 2C18enzyme
DB00349ClobazamSodium- and chloride-dependent GABA transporter 1transporter
DB00349ClobazamSodium- and chloride-dependent GABA transporter 3transporter
DB00349ClobazamP-glycoprotein 1transporter
DB00349ClobazamGABA-A receptor (anion channel)target
DB00349ClobazamCytochrome P450 2D6enzyme
DB00996GabapentinAdenosine receptor A1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00996GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
DB00996GabapentinLarge neutral amino acids transporter small subunit 1transporter
DB00996GabapentinVoltage-dependent N-type calcium channeltarget
DB00996GabapentinPotassium voltage-gated channel subfamily KQT member 3target
DB00996GabapentinPotassium voltage-gated channel subfamily KQT member 5target
DB01202LevetiracetamSynaptic vesicle glycoprotein 2Atarget
DB01202LevetiracetamP-glycoprotein 1transporter
DB01202LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00909ZonisamideSodium channel protein type 1 subunit alphatarget
DB00909ZonisamideCarbonic anhydrase 1target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00909ZonisamideCytochrome P450 3A4enzyme
DB00909ZonisamideAldehyde oxidaseenzyme
DB00909ZonisamideAmine oxidase [flavin-containing] Btarget
DB00909ZonisamideCarbonic anhydrase 2target
DB00909ZonisamideCarbonic anhydrase 3target
DB00909ZonisamideCarbonic anhydrase 4target
DB00909ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 6target
DB00909ZonisamideCarbonic anhydrase 7target
DB00909ZonisamideCarbonic anhydrase-related proteintarget
DB00909ZonisamideCarbonic anhydrase 9target
DB00909ZonisamideCarbonic anhydrase-related protein 10target
DB00909ZonisamideCarbonic anhydrase-related protein 11target
DB00909ZonisamideCarbonic anhydrase 12target
DB00909ZonisamideCarbonic anhydrase 13target
DB00909ZonisamideCarbonic anhydrase 14target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00909ZonisamideSodium channel protein type 2 subunit alphatarget
DB00909ZonisamideSodium channel protein type 3 subunit alphatarget
DB00909ZonisamideSodium channel protein type 4 subunit alphatarget
DB00909ZonisamideSodium channel protein type 5 subunit alphatarget
DB00909ZonisamideSodium channel protein type 9 subunit alphatarget
DB00909ZonisamideSodium channel protein type 11 subunit alphatarget
DB00909ZonisamideSodium channel subunit beta-1target
DB00909ZonisamideSodium channel subunit beta-2target
DB00909ZonisamideSodium channel subunit beta-3target
DB00909ZonisamideSodium channel subunit beta-4target
DB00909ZonisamideAmine oxidase [flavin-containing] Atarget
DB00909ZonisamideCytochrome P450 2C19enzyme
DB00909ZonisamideUDP-glucuronosyltransferase 1-1enzyme
DB00909ZonisamideCytochrome P450 3A5enzyme
DrugDrug NamePhaseStatusCount
DB00252Phenytoin0Terminated1
DB00273Topiramate0Terminated1
DB01076Atorvastatin1Completed1
DB05541Brivaracetam1Completed3
DB09061Cannabidiol1Active Not Recruiting3
DB14050Cannabidivarin1Completed1
DB00564Carbamazepine1Completed2
DB00829Diazepam1Completed1
DB00390Digoxin1Completed2
DB09119Eslicarbazepine acetate1Completed25
DB09119Eslicarbazepine acetate1Terminated2
DB04953Ezogabine1Completed3
DB00996Gabapentin1Completed1
DB01120Gliclazide1Completed1
DB06218Lacosamide1Completed1
DB00555Lamotrigine1Completed9
DB01202Levetiracetam1Completed2
DB00186Lorazepam1Completed1
DB06796Mangafodipir1Recruiting1
DB00683Midazolam1Terminated1
DB00218Moxifloxacin1Completed1
DB12458Muscimol1Terminated1
DB11632Opicapone1Completed1
DB00776Oxcarbazepine1Completed4
DB14977Padsevonil1Completed1
DB01267Paliperidone1Completed1
DB00252Phenytoin1Completed2
DB00252Phenytoin1Terminated1
DB00641Simvastatin1Completed1
DB08329Sulthiame1Active Not Recruiting1
DB00273Topiramate1Completed4
DB11677Triheptanoin1Active Not Recruiting1
DB00313Valproic acid1Completed4
DB00313Valproic acid1Unknown Status1
DB00682Warfarin1Completed1
DB00829Diazepam1 / 2Recruiting1
DB01590Everolimus1 / 2Completed1
DB00555Lamotrigine1 / 2Completed1
DB01202Levetiracetam1 / 2Completed1
DB00313Valproic acid1 / 2Active Not Recruiting1
DB12131Vinpocetine1 / 2Recruiting1
DB00316Acetaminophen2Not Yet Recruiting1
DB00945Acetylsalicylic acid2Recruiting1
DB05690Alprazolam2Completed1
DB05690Alprazolam2Recruiting1
DB05016Ataluren2Active Not Recruiting1
DB05541Brivaracetam2Completed4
DB05541Brivaracetam2Recruiting1
DB00490Buspirone2Terminated1
DB09061Cannabidiol2Completed5
DB14050Cannabidivarin2Completed2
DB00564Carbamazepine2Completed1
DB06119Cenobamate2Completed1
DB00349Clobazam2Completed3
DB01068Clonazepam2Completed1
DB00286Conjugated estrogens2Completed1
DB01285Corticotropin2Completed1
DB00829Diazepam2Completed2
DB00829Diazepam2Recruiting1
DB00829Diazepam2Terminated1
DB09119Eslicarbazepine acetate2Completed3
DB01590Everolimus2Recruiting1
DB04953Ezogabine2Terminated1
DB00574Fenfluramine2Active Not Recruiting1
DB13961Fish oil2Completed1
DB00472Fluoxetine2Completed1
DB05087Ganaxolone2Active Not Recruiting1
DB05087Ganaxolone2Recruiting1
DB06089ICA-1056652Terminated1
DB01050Ibuprofen2Not Yet Recruiting1
DB06218Lacosamide2Active Not Recruiting1
DB06218Lacosamide2Completed5
DB00555Lamotrigine2Completed2
DB01202Levetiracetam2Completed9
DB01202Levetiracetam2Enrolling by Invitation1
DB00186Lorazepam2Completed1
DB14009Medical Cannabis2Recruiting1
DB00603Medroxyprogesterone acetate2Completed1
DB01065Melatonin2Completed1
DB05562Naluzotan2Terminated1
DB01115Nifedipine2Not Yet Recruiting1
DB00393Nimodipine2Not Yet Recruiting1
DB01595Nitrazepam2Completed1
DB11133Omega-3 fatty acids2Recruiting1
DB09539Omega-3-acid ethyl esters2Recruiting1
DB08883Perampanel2Completed5
DB08883Perampanel2Recruiting2
DB00165Pyridoxine2Completed1
DB12367Selurampanel2Completed1
DB04982Talampanel2Completed1
DB00273Topiramate2Completed5
DB11677Triheptanoin2Recruiting1
DB05507VX-7652Terminated1
DB00313Valproic acid2Completed1
DB00661Verapamil2Unknown Status1
DB00518Albendazole2 / 3Completed1
DB01136Carvedilol2 / 3Terminated1
DB06218Lacosamide2 / 3Completed1
DB01058Praziquantel2 / 3Completed1
DB05541Brivaracetam3Completed11
DB05541Brivaracetam3Enrolling by Invitation2
DB05541Brivaracetam3Recruiting2
DB05541Brivaracetam3Terminated2
DB01156Bupropion3Completed1
DB09061Cannabidiol3Active Not Recruiting1
DB09061Cannabidiol3Completed4
DB09061Cannabidiol3Not Yet Recruiting1
DB00564Carbamazepine3Completed8
DB12338Carisbamate3Completed1
DB12338Carisbamate3Terminated1
DB01563Chloral hydrate3Completed1
DB00349Clobazam3Completed1
DB00349Clobazam3Terminated1
DB01068Clonazepam3Completed1
DB01068Clonazepam3Terminated1
DB00829Diazepam3Completed1
DB00829Diazepam3Recruiting1
DB09119Eslicarbazepine acetate3Completed4
DB09119Eslicarbazepine acetate3Withdrawn1
DB00593Ethosuximide3Completed1
DB04953Ezogabine3Completed5
DB04953Ezogabine3Terminated3
DB00472Fluoxetine3Completed1
DB00158Folic acid3Unknown Status1
DB01320Fosphenytoin3Completed2
DB01221Ketamine3Withdrawn1
DB06218Lacosamide3Active Not Recruiting2
DB06218Lacosamide3Completed14
DB06218Lacosamide3Enrolling by Invitation1
DB06218Lacosamide3Unknown Status1
DB06218Lacosamide3Withdrawn1
DB00555Lamotrigine3Completed10
DB00555Lamotrigine3Terminated1
DB01202Levetiracetam3Active Not Recruiting1
DB01202Levetiracetam3Completed15
DB01202Levetiracetam3Terminated2
DB01202Levetiracetam3Unknown Status1
DB01202Levetiracetam3Withdrawn1
DB00186Lorazepam3Completed1
DB00186Lorazepam3Terminated1
DB01065Melatonin3Completed1
DB00683Midazolam3Completed1
DB00683Midazolam3Terminated2
DB01183Naloxone3Recruiting1
DB00776Oxcarbazepine3Completed3
DB08883Perampanel3Completed2
DB01174Phenobarbital3Completed1
DB01174Phenobarbital3Withdrawn1
DB00252Phenytoin3Completed1
DB00230Pregabalin3Completed1
DB00230Pregabalin3Terminated1
DB00396Progesterone3Completed1
DB06201Rufinamide3Completed1
DB05885Seletracetam3Withdrawn2
DB12175Seletracetam3Withdrawn2
DB01104Sertraline3Completed1
DB00273Topiramate3Active Not Recruiting1
DB00273Topiramate3Completed13
DB00273Topiramate3Terminated1
DB00313Valproic acid3Completed3
DB09328Vayarin3Completed1
DB11094Vitamin D3Recruiting1
DB00909Zonisamide3Completed3
DB00909Zonisamide3Terminated2
DB03568Butyric Acid4Recruiting1
DB00564Carbamazepine4Completed6
DB00564Carbamazepine4Recruiting2
DB00169Cholecalciferol4Completed1
DB04920Clevidipine4Completed1
DB00349Clobazam4Recruiting3
DB01068Clonazepam4Recruiting1
DB00633Dexmedetomidine4Active Not Recruiting1
DB01175Escitalopram4Enrolling by Invitation1
DB01175Escitalopram4Terminated1
DB01175Escitalopram4Withdrawn1
DB09119Eslicarbazepine acetate4Completed2
DB00593Ethosuximide4Recruiting1
DB04953Ezogabine4Terminated1
DB00996Gabapentin4Completed2
DB00602Ivermectin4Completed2
DB06218Lacosamide4Completed2
DB06218Lacosamide4Not Yet Recruiting1
DB00555Lamotrigine4Completed9
DB00555Lamotrigine4Recruiting2
DB00555Lamotrigine4Unknown Status1
DB01202Levetiracetam4Completed11
DB01202Levetiracetam4Recruiting2
DB00367Levonorgestrel4Completed1
DB00422Methylphenidate4Completed2
DB00683Midazolam4Active Not Recruiting1
DB01595Nitrazepam4Recruiting1
DB00776Oxcarbazepine4Completed1
DB08883Perampanel4Completed1
DB08883Perampanel4Recruiting1
DB08883Perampanel4Terminated1
DB00252Phenytoin4Completed1
DB00252Phenytoin4Recruiting1
DB00252Phenytoin4Terminated1
DB00230Pregabalin4Completed2
DB00230Pregabalin4Terminated1
DB01032Probenecid4Terminated1
DB00818Propofol4Active Not Recruiting1
DB00884Risedronic acid4Completed1
DB06201Rufinamide4Recruiting1
DB01104Sertraline4Terminated1
DB09118Stiripentol4Recruiting1
DB00273Topiramate4Completed8
DB00273Topiramate4Recruiting2
DB00273Topiramate4Unknown Status1
DB00313Valproic acid4Completed5
DB00313Valproic acid4Recruiting1
DB00313Valproic acid4Unknown Status1
DB01080Vigabatrin4Recruiting1
DB00163Vitamin E4Completed1
DB00909Zonisamide4Completed8
DB00909Zonisamide4Recruiting1
DB00909Zonisamide4Terminated2
DB00518AlbendazoleNot AvailableCompleted1
DB00802AlfentanilNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic acidNot AvailableRecruiting1
DB00559BosentanNot AvailableRecruiting1
DB05541BrivaracetamNot AvailableAvailable1
DB05541BrivaracetamNot AvailableNot Yet Recruiting1
DB00297BupivacaineNot AvailableCompleted1
DB09061CannabidiolNot AvailableApproved for Marketing1
DB09061CannabidiolNot AvailableAvailable1
DB09061CannabidiolNot AvailableNo Longer Available1
DB00564CarbamazepineNot AvailableCompleted3
DB00564CarbamazepineNot AvailableRecruiting1
DB01413CefepimeNot AvailableRecruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00349ClobazamNot AvailableRecruiting1
DB00363ClozapineNot AvailableRecruiting1
DB01234DexamethasoneNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableCompleted1
DB00668EpinephrineNot AvailableCompleted1
DB09119Eslicarbazepine acetateNot AvailableCompleted2
DB00593EthosuximideNot AvailableCompleted1
DB04953EzogabineNot AvailableCompleted2
DB04953EzogabineNot AvailableTerminated1
DB00949FelbamateNot AvailableCompleted1
DB00828FosfomycinNot AvailableRecruiting1
DB00996GabapentinNot AvailableCompleted2
DB00502HaloperidolNot AvailableRecruiting1
DB00598LabetalolNot AvailableRecruiting1
DB06218LacosamideNot AvailableCompleted3
DB00555LamotrigineNot AvailableCompleted10
DB00555LamotrigineNot AvailableRecruiting1
DB01202LevetiracetamNot AvailableCompleted7
DB01202LevetiracetamNot AvailableRecruiting1
DB01202LevetiracetamNot AvailableUnknown Status1
DB00281LidocaineNot AvailableCompleted1
DB08815LurasidoneNot AvailableRecruiting1
DB01043MemantineNot AvailableCompleted1
DB01043MemantineNot AvailableWithdrawn1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB00776OxcarbazepineNot AvailableCompleted4
DB00776OxcarbazepineNot AvailableRecruiting1
DB00497OxycodoneNot AvailableRecruiting1
DB00312PentobarbitalNot AvailableRecruiting1
DB08883PerampanelNot AvailableCompleted2
DB08883PerampanelNot AvailableNot Yet Recruiting1
DB08883PerampanelNot AvailableRecruiting1
DB01174PhenobarbitalNot AvailableCompleted2
DB01174PhenobarbitalNot AvailableRecruiting1
DB01174PhenobarbitalNot AvailableWithdrawn1
DB00252PhenytoinNot AvailableCompleted2
DB00252PhenytoinNot AvailableRecruiting1
DB00319PiperacillinNot AvailableRecruiting1
DB00230PregabalinNot AvailableCompleted4
DB00794PrimidoneNot AvailableCompleted1
DB00818PropofolNot AvailableCompleted1
DB00899RemifentanilNot AvailableCompleted1
DB00728RocuroniumNot AvailableRecruiting1
DB00658SevelamerNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableRecruiting1
DB09118StiripentolNot AvailableRecruiting1
DB01606TazobactamNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00273TopiramateNot AvailableCompleted2
DB00273TopiramateNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00313Valproic acidNot AvailableCompleted6
DB00313Valproic acidNot AvailableRecruiting1
DB00313Valproic acidNot AvailableUnknown Status1
DB00512VancomycinNot AvailableRecruiting1
DB01339VecuroniumNot AvailableRecruiting1
DB00661VerapamilNot AvailableUnknown Status1
DB01080VigabatrinNot AvailableCompleted1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1
DB00909ZonisamideNot AvailableCompleted2