Glioblastomas

Also known as: Glioblastoma

DrugDrug NameDrug Description
DB00112BevacizumabA monoclonal anti-vascular endothelial growth factor antibody used in the treatment of many cancer types in combination with other antineoplastics.
DB00262CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
DB00762IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
DrugDrug NameTargetType
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00112BevacizumabComplement C1r subcomponenttarget
DB00112BevacizumabComplement C1q subcomponent subunit Atarget
DB00112BevacizumabComplement C1q subcomponent subunit Btarget
DB00112BevacizumabComplement C1q subcomponent subunit Ctarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00112BevacizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00112BevacizumabVascular endothelial growth factor Atarget
DB00262CarmustineGlutathione reductase, mitochondrialtarget
DB00262CarmustineDNAtarget
DB00262CarmustineRNAtarget
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanP-glycoprotein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DrugDrug NamePhaseStatusCount
DB12001Abemaciclib0Not Yet Recruiting1
DB00112Bevacizumab0Completed1
DB00112Bevacizumab0Not Yet Recruiting1
DB00112Bevacizumab0Terminated1
DB00112Bevacizumab0Unknown Status1
DB04690Camptothecin0Terminated1
DB01136Carvedilol0Not Yet Recruiting1
DB01136Carvedilol0Recruiting1
DB09063Ceritinib0Recruiting1
DB00822Disulfiram0Completed1
DB00822Disulfiram0Recruiting1
DB06215Ferumoxytol0Completed1
DB08868Fingolimod0Completed1
DB00762Irinotecan0Terminated1
DB09570Ixazomib0Completed1
DB11740MK-17750Active Not Recruiting1
DB00331Metformin0Recruiting1
DB12893Sacituzumab govitecan0Recruiting1
DB01268Sunitinib0Completed1
DB00853Temozolomide0Active Not Recruiting1
DB00853Temozolomide0Completed1
DB00853Temozolomide0Recruiting1
DB119196-O-benzylguanine1Completed1
DB15299AMG-2321Recruiting1
DB08916Afatinib1Completed1
DB00041Aldesleukin1Completed1
DB11200Aluminum zirconium octachlorohydrex gly1Recruiting1
DB11200Aluminum zirconium octachlorohydrex gly1Withdrawn1
DB00126Ascorbic acid1Active Not Recruiting1
DB00126Ascorbic acid1Terminated2
DB14857Avadomide1Active Not Recruiting1
DB11945Avelumab1Recruiting1
DB06626Axitinib1Withdrawn1
DB00112Bevacizumab1Active Not Recruiting1
DB00112Bevacizumab1Completed1
DB00112Bevacizumab1Not Yet Recruiting1
DB00112Bevacizumab1Recruiting1
DB00112Bevacizumab1Terminated1
DB00112Bevacizumab1Withdrawn1
DB11666Buparlisib1Completed1
DB05153Cabozantinib1Completed1
DB08875Cabozantinib1Completed1
DB01373Calcium1Recruiting1
DB01101Capecitabine1Recruiting1
DB12029Chlorogenic Acid1Completed1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)1Active Not Recruiting1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)1Active Not Recruiting1
DB08865Crizotinib1Withdrawn1
DB05487Custirsen1Completed1
DB00531Cyclophosphamide1Recruiting1
DB00531Cyclophosphamide1Terminated1
DB01254Dasatinib1Completed1
DB01254Dasatinib1Terminated1
DB08809Dichloroacetic acid1Completed1
DB08809Dichloroacetic acid1Withdrawn1
DB00997Doxorubicin1Active Not Recruiting1
DB00997Doxorubicin1Recruiting1
DB11717Epacadostat1Recruiting1
DB00530Erlotinib1Completed1
DB00773Etoposide1Completed1
DB00773Etoposide1Recruiting1
DB01590Everolimus1Completed1
DB01590Everolimus1Recruiting1
DB00099Filgrastim1Recruiting1
DB01099Flucytosine1Completed1
DB00317Gefitinib1Completed1
DB00441Gemcitabine1Recruiting1
DB14865Human interleukin-21Completed1
DB01005Hydroxyurea1Completed2
DB01005Hydroxyurea1Recruiting1
DB09053Ibrutinib1Recruiting1
DB00619Imatinib1Completed2
DB00724Imiquimod1Completed1
DB00724Imiquimod1Terminated1
DB06186Ipilimumab1Active Not Recruiting1
DB06186Ipilimumab1Recruiting3
DB00762Irinotecan1Completed5
DB00650Leucovorin1Recruiting1
DB14986Linrodostat1Recruiting1
DB15224Lisavanbulin1Recruiting1
DB06448Lonafarnib1Completed1
DB11740MK-17751Active Not Recruiting1
DB11740MK-17751Recruiting1
DB08932Macitentan1Terminated2
DB11762Marizomib1Active Not Recruiting1
DB00643Mebendazole1Recruiting1
DB14009Medical Cannabis1Terminated1
DB00358Mefloquine1Active Not Recruiting1
DB01043Memantine1Active Not Recruiting1
DB00331Metformin1Active Not Recruiting1
DB05428Motexafin gadolinium1Completed1
DB00220Nelfinavir1Completed1
DB09035Nivolumab1Active Not Recruiting2
DB09035Nivolumab1Recruiting8
DB15463PT29771Recruiting1
DB14769Pamiparib1Recruiting1
DB00019Pegfilgrastim1Completed1
DB09037Pembrolizumab1Active Not Recruiting1
DB09037Pembrolizumab1Recruiting2
DB05240Pilaralisib1Completed1
DB11772Pilaralisib1Completed1
DB12060RRx-0011Active Not Recruiting1
DB15185Rasdegafusp alfa1Completed1
DB06213Regadenoson1Not Yet Recruiting1
DB05386Regramostim1Active Not Recruiting1
DB05386Regramostim1Recruiting1
DB14851Relatlimab1Recruiting1
DB11730Ribociclib1Active Not Recruiting1
DB11730Ribociclib1Recruiting2
DB06233Ridaforolimus1Completed1
DB08877Ruxolitinib1Recruiting1
DB11836Sapanisertib1Active Not Recruiting1
DB00020Sargramostim1Completed2
DB00020Sargramostim1Terminated1
DB00877Sirolimus1Completed2
DB09143Sonidegib1Recruiting1
DB00398Sorafenib1Completed1
DB00398Sorafenib1Terminated1
DB00398Sorafenib1Withdrawn1
DB01268Sunitinib1Completed1
DB01268Sunitinib1Withdrawn1
DB00853Temozolomide1Active Not Recruiting7
DB00853Temozolomide1Completed10
DB00853Temozolomide1Not Yet Recruiting2
DB00853Temozolomide1Recruiting11
DB00853Temozolomide1Terminated7
DB15147Tinostamustine1Recruiting1
DB01030Topotecan1Completed1
DB08911Trametinib1Recruiting1
DB09270Ubidecarenone1Active Not Recruiting1
DB12077Urelumab1Recruiting1
DB00313Valproic acid1Recruiting1
DB00313Valproic acid1Withdrawn1
DB05294Vandetanib1Completed3
DB04879Vatalanib1Completed1
DB12170Veledimex1Active Not Recruiting1
DB12170Veledimex1Recruiting1
DB15331Vocimagene amiretrorepvec1Completed1
DB02546Vorinostat1Completed1
DB02546Vorinostat1Recruiting1
DB12400Voxtalisib1Completed1
DB05241XL7651Completed1
DB119196-O-benzylguanine1 / 2Active Not Recruiting1
DB00041Aldesleukin1 / 2Completed1
DB11885Anlotinib1 / 2Recruiting1
DB00673Aprepitant1 / 2Active Not Recruiting1
DB11595Atezolizumab1 / 2Recruiting1
DB00995Auranofin1 / 2Active Not Recruiting1
DB11945Avelumab1 / 2Not Yet Recruiting1
DB00112Bevacizumab1 / 2Active Not Recruiting1
DB00112Bevacizumab1 / 2Completed1
DB00112Bevacizumab1 / 2Not Yet Recruiting1
DB00188Bortezomib1 / 2Recruiting1
DB01101Capecitabine1 / 2Recruiting1
DB01197Captopril1 / 2Active Not Recruiting1
DB00958Carboplatin1 / 2Completed1
DB00262Carmustine1 / 2Active Not Recruiting1
DB00482Celecoxib1 / 2Active Not Recruiting1
DB14707Cemiplimab1 / 2Active Not Recruiting1
DB00002Cetuximab1 / 2Recruiting1
DB00531Cyclophosphamide1 / 2Completed1
DB11651Dactolisib1 / 2Enrolling by Invitation1
DB01254Dasatinib1 / 2Terminated1
DB12826Depatuxizumab1 / 2Active Not Recruiting1
DB11731Depatuxizumab mafodotin1 / 2Active Not Recruiting1
DB12873Dianhydrogalactitol1 / 2Completed1
DB00822Disulfiram1 / 2Active Not Recruiting1
DB00997Doxorubicin1 / 2Completed1
DB11714Durvalumab1 / 2Suspended1
DB06486Enzastaurin1 / 2Completed1
DB11717Epacadostat1 / 2Active Not Recruiting1
DB11717Epacadostat1 / 2Not Yet Recruiting1
DB01590Everolimus1 / 2Recruiting1
DB00099Filgrastim1 / 2Active Not Recruiting1
DB01099Flucytosine1 / 2Recruiting1
DB01073Fludarabine1 / 2Completed1
DB11911Galunisertib1 / 2Active Not Recruiting1
DB11978Glasdegib1 / 2Recruiting1
DB05266Ibudilast1 / 2Recruiting1
DB05975Iniparib1 / 2Completed1
DB11743Ipatasertib1 / 2Enrolling by Invitation1
DB00762Irinotecan1 / 2Recruiting1
DB01167Itraconazole1 / 2Active Not Recruiting1
DB01206Lomustine1 / 2Terminated1
DB00742Mannitol1 / 2Recruiting1
DB11762Marizomib1 / 2Active Not Recruiting1
DB01017Minocycline1 / 2Active Not Recruiting1
DB12155Napabucasin1 / 2Completed1
DB09035Nivolumab1 / 2Active Not Recruiting2
DB11707Olaptesed Pegol1 / 2Recruiting1
DB09037Pembrolizumab1 / 2Enrolling by Invitation1
DB09037Pembrolizumab1 / 2Recruiting1
DB12802Picropodophyllin1 / 2Unknown Status1
DB11663Pictilisib1 / 2Enrolling by Invitation1
DB06809Plerixafor1 / 2Active Not Recruiting1
DB00503Ritonavir1 / 2Active Not Recruiting1
DB13017Rovalpituzumab Tesirine1 / 2Terminated1
DB14896Selitrectinib1 / 2Recruiting1
DB01104Sertraline1 / 2Active Not Recruiting1
DB00398Sorafenib1 / 2Recruiting1
DB00853Temozolomide1 / 2Active Not Recruiting5
DB00853Temozolomide1 / 2Completed5
DB00853Temozolomide1 / 2Not Yet Recruiting2
DB00853Temozolomide1 / 2Recruiting10
DB05974Transcrocetinate1 / 2Active Not Recruiting1
DB07232Veliparib1 / 2Completed1
DB02546Vorinostat1 / 2Completed1
DB12001Abemaciclib2Active Not Recruiting1
DB12001Abemaciclib2Not Yet Recruiting1
DB12001Abemaciclib2Recruiting1
DB00945Acetylsalicylic acid2Terminated1
DB15074Aglatimagene besadenovec2Completed1
DB00041Aldesleukin2Recruiting2
DB06013Aldoxorubicin2Completed1
DB00855Aminolevulinic acid2Completed2
DB00855Aminolevulinic acid2Not Yet Recruiting1
DB00855Aminolevulinic acid2Terminated1
DB00855Aminolevulinic acid2Withdrawn1
DB11945Avelumab2Active Not Recruiting1
DB00074Basiliximab2Active Not Recruiting1
DB05136Bavituximab2Active Not Recruiting1
DB00112Bevacizumab2Active Not Recruiting7
DB00112Bevacizumab2Completed21
DB00112Bevacizumab2Recruiting6
DB00112Bevacizumab2Terminated1
DB00112Bevacizumab2Withdrawn1
DB12182Binetrakin2Active Not Recruiting1
DB11967Binimetinib2Active Not Recruiting1
DB00188Bortezomib2Completed1
DB06616Bosutinib2Completed1
DB11666Buparlisib2Completed1
DB12740CC-1152Recruiting1
DB00958Carboplatin2Recruiting1
DB00262Carmustine2Completed1
DB06322Carotuximab2Completed1
DB04849Cediranib2Terminated1
DB14707Cemiplimab2Recruiting1
DB09063Ceritinib2Completed1
DB00002Cetuximab2Recruiting1
DB00002Cetuximab2Terminated1
DB00608Chloroquine2Not Yet Recruiting1
DB11890Cilengitide2Completed1
DB11890Cilengitide2Terminated1
DB11890Cilengitide2Withdrawn1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)2Recruiting2
DB00531Cyclophosphamide2Recruiting4
DB08912Dabrafenib2Recruiting2
DB11963Dacomitinib2Completed2
DB01254Dasatinib2Withdrawn1
DB12873Dianhydrogalactitol2Recruiting2
DB00822Disulfiram2Recruiting1
DB11714Durvalumab2Active Not Recruiting1
DB11718Encorafenib2Active Not Recruiting1
DB06486Enzastaurin2Not Yet Recruiting1
DB00530Erlotinib2Completed4
DB00773Etoposide2Completed2
DB00773Etoposide2Recruiting1
DB06091Evofosfamide2Active Not Recruiting1
DB06215Ferumoxytol2Recruiting1
DB01073Fludarabine2Recruiting2
DB09502Fludeoxyglucose (18F)2Recruiting1
DB11911Galunisertib2Active Not Recruiting1
DB00317Gefitinib2Completed1
DB00317Gefitinib2Terminated1
DB05036Grn163l2Terminated1
DB01611Hydroxychloroquine2Completed1
DB01005Hydroxyurea2Completed2
DB00619Imatinib2Completed2
DB00619Imatinib2Terminated1
DB11659Indium2Recruiting1
DB12827Indoximod2Recruiting1
DB00762Irinotecan2Completed4
DB14723Larotrectinib2Recruiting1
DB00480Lenalidomide2Completed1
DB09078Lenvatinib2Recruiting1
DB01206Lomustine2Active Not Recruiting1
DB01206Lomustine2Completed3
DB01206Lomustine2Recruiting2
DB01601Lopinavir2Terminated1
DB00678Losartan2Recruiting1
DB05477MUC1 Dendritic Cell Vaccine2Completed1
DB00742Mannitol2Recruiting1
DB01043Memantine2Terminated1
DB00331Metformin2Recruiting1
DB11813Mipsagargin2Withdrawn1
DB11828Neratinib2Recruiting1
DB06192Nimotuzumab2Completed1
DB13069Nimustine2Completed1
DB09079Nintedanib2Completed1
DB09035Nivolumab2Recruiting3
DB14844ONC-2012Recruiting1
DB09074Olaparib2Recruiting1
DB11746Onartuzumab2Completed1
DB11669Ortataxel2Completed1
DB09330Osimertinib2Recruiting1
DB06171Paclitaxel trevatide2Completed1
DB09073Palbociclib2Terminated1
DB06589Pazopanib2Completed1
DB06589Pazopanib2Terminated1
DB09037Pembrolizumab2Active Not Recruiting2
DB09037Pembrolizumab2Completed1
DB09037Pembrolizumab2Not Yet Recruiting1
DB09037Pembrolizumab2Recruiting5
DB09037Pembrolizumab2Suspended1
DB06641Perifosine2Active Not Recruiting1
DB06809Plerixafor2Recruiting1
DB08901Ponatinib2Completed1
DB00178Ramipril2Recruiting1
DB05386Regramostim2Completed1
DB05386Regramostim2Recruiting1
DB06530Resiquimod2Active Not Recruiting1
DB05374Rindopepimut2Completed1
DB00503Ritonavir2Terminated1
DB05332Romiplostim2Terminated1
DB05654Sagopilone2Completed1
DB00020Sargramostim2Active Not Recruiting1
DB00020Sargramostim2Recruiting2
DB11942Selinexor2Active Not Recruiting1
DB00203Sildenafil2Recruiting1
DB00877Sirolimus2Completed1
DB09153Sodium chloride2Recruiting1
DB14754Solriamfetol2Not Yet Recruiting1
DB12601Sonolisib2Completed1
DB00398Sorafenib2Recruiting1
DB00398Sorafenib2Withdrawn1
DB02772Sucrose2Recruiting1
DB01268Sunitinib2Completed2
DB05465Tandutinib2Completed1
DB00853Temozolomide2Active Not Recruiting9
DB00853Temozolomide2Completed17
DB00853Temozolomide2Not Yet Recruiting3
DB00853Temozolomide2Recruiting11
DB00853Temozolomide2Suspended2
DB00853Temozolomide2Terminated3
DB00853Temozolomide2Unknown Status2
DB00853Temozolomide2Withdrawn2
DB06287Temsirolimus2Active Not Recruiting1
DB05007Tesevatinib2Active Not Recruiting1
DB11973Tesevatinib2Active Not Recruiting1
DB01041Thalidomide2Unknown Status1
DB11800Tivozanib2Completed1
DB01030Topotecan2Active Not Recruiting1
DB01030Topotecan2Completed1
DB08911Trametinib2Recruiting2
DB12056Trebananib2Active Not Recruiting1
DB00313Valproic acid2Recruiting1
DB11930Varlilumab2Suspended1
DB12170Veledimex2Recruiting1
DB07232Veliparib2Recruiting1
DB00541Vincristine2Recruiting1
DB06400Vitespen2Recruiting1
DB05299keyhole limpet hemocyanin2Active Not Recruiting1
DB12826Depatuxizumab2 / 3Active Not Recruiting1
DB11731Depatuxizumab mafodotin2 / 3Active Not Recruiting1
DB00822Disulfiram2 / 3Recruiting1
DB01099Flucytosine2 / 3Not Yet Recruiting1
DB00762Irinotecan2 / 3Unknown Status1
DB01206Lomustine2 / 3Recruiting3
DB08896Regorafenib2 / 3Recruiting1
DB01268Sunitinib2 / 3Recruiting1
DB00853Temozolomide2 / 3Active Not Recruiting2
DB00853Temozolomide2 / 3Not Yet Recruiting2
DB00853Temozolomide2 / 3Recruiting3
DB07232Veliparib2 / 3Active Not Recruiting1
DB15331Vocimagene amiretrorepvec2 / 3Not Yet Recruiting1
DB00112Bevacizumab3Completed3
DB00112Bevacizumab3Recruiting1
DB00958Carboplatin3Active Not Recruiting1
DB00262Carmustine3Completed1
DB00262Carmustine3Terminated1
DB00262Carmustine3Unknown Status1
DB11890Cilengitide3Completed1
DB12873Dianhydrogalactitol3Active Not Recruiting1
DB04882Edotecarin3Completed1
DB06486Enzastaurin3Completed1
DB01206Lomustine3Active Not Recruiting1
DB01206Lomustine3Completed3
DB01206Lomustine3Terminated1
DB05477MUC1 Dendritic Cell Vaccine3Active Not Recruiting1
DB15175Ofranergene obadenovec3Completed1
DB05374Rindopepimut3Completed1
DB05337SOT-1073Completed1
DB00020Sargramostim3Completed1
DB13647Semustine3Completed1
DB00853Temozolomide3Active Not Recruiting1
DB00853Temozolomide3Completed8
DB00853Temozolomide3Recruiting3
DB00853Temozolomide3Terminated1
DB05974Transcrocetinate3Active Not Recruiting1
DB08912Dabrafenib4Not Yet Recruiting1
DB00853Temozolomide4Completed1
DB08911Trametinib4Not Yet Recruiting1
DB00855Aminolevulinic acidNot AvailableActive Not Recruiting1
DB00112BevacizumabNot AvailableCompleted1
DB00112BevacizumabNot AvailableTerminated1
DB00262CarmustineNot AvailableUnknown Status1
DB12091GadoliniumNot AvailableWithdrawn1
DB06186IpilimumabNot AvailableNo Longer Available1
DB11716MisonidazoleNot AvailableTerminated1
DB14765RivoceranibNot AvailableRecruiting1
DB00853TemozolomideNot AvailableCompleted4
DB00853TemozolomideNot AvailableRecruiting2
DB00853TemozolomideNot AvailableTerminated1