Chronic Renal Failure (CRF)

Also known as: Chronic Renal Failure / Renal Failure , Chronic / Renal Failure, Chronic / Kidney Failure Chronic / End Stage Renal Failure / Renal Failure Chronic / Chronic Kidney Failure / Kidney Failure, Chronic / Kidney Failure,Chronic / Chronic uremia / End stage renal disease (ESRD) / Chronic renal disease / Chronic kidney disease / Chronic Kidney Diseases

DrugDrug NameDrug Description
DB01436AlfacalcidolA vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure.
DB00136CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
DB00258Calcium acetateA phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism.
DB00746DeferoxamineA chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias.
DB11624Epoetin deltaEpoetin Delta is an ingredient in the EMA-withdrawn product Dynepo.
DB00774HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
DB00232MethyclothiazideA diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy.
DB01324PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
DrugDrug NameTargetType
DB01436AlfacalcidolVitamin D-binding proteincarrier
DB01436AlfacalcidolVitamin D3 receptortarget
DB01436Alfacalcidol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialtarget
DB01436AlfacalcidolRetinoic acid receptor RXR-alphatarget
DB00136CalcitriolVitamin D3 receptortarget
DB00136Calcitriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB00136CalcitriolCytochrome P450 3A4enzyme
DB00136CalcitriolHomeobox protein Hox-A10target
DB00136CalcitriolVitamin D-binding proteincarrier
DB00258Calcium acetatePhosphatetarget
DB00746DeferoxamineXanthine dehydrogenase/oxidaseenzyme
DB00746DeferoxamineIrontarget
DB00746DeferoxamineAluminumtarget
DB00746DeferoxamineAmyloid beta A4 proteintarget
DB00774HydroflumethiazideSolute carrier family 12 member 1target
DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 4target
DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 2target
DB00774HydroflumethiazideCarbonic anhydrase 1target
DB00774HydroflumethiazideCarbonic anhydrase 9target
DB00774HydroflumethiazideCarbonic anhydrase 12target
DB00774HydroflumethiazideSerum albumincarrier
DB00774HydroflumethiazideSolute carrier family 22 member 6transporter
DB00774HydroflumethiazideSolute carrier family 22 member 8transporter
DB00774HydroflumethiazideCarbonic anhydrase 7target
DB00232MethyclothiazideSolute carrier family 12 member 1target
DB00232MethyclothiazideCarbonic anhydrase 4target
DB00232MethyclothiazideCarbonic anhydrase 2target
DB00232MethyclothiazideCarbonic anhydrase 1target
DB01324PolythiazideSolute carrier family 12 member 3target
DB01324PolythiazideSolute carrier family 22 member 6transporter
DB01324PolythiazideSolute carrier family 22 member 8transporter
DB01324PolythiazideSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB14276Turmeric0Completed1
DB11704Adomeglivant1Completed1
DB12139Alisporivir1Completed1
DB00993Azathioprine1Completed1
DB06681Belatacept1Active Not Recruiting1
DB00146Calcifediol1Completed1
DB06695Dabigatran etexilate1Completed1
DB06410Doxercalciferol1Completed1
DB15077Efinopegdutide1Completed1
DB00016Erythropoietin1Completed2
DB00016Erythropoietin1Unknown Status1
DB14488Ferrous gluconate1Completed1
DB09132Gadoteric acid1Completed1
DB00028Human immunoglobulin G1Completed1
DB09146Iron sucrose1Completed1
DB06792Lanthanum carbonate1Completed1
DB00305Mitomycin1Completed1
DB08935Obinutuzumab1Completed1
DB08894Peginesatide1Completed1
DB14974Pimodivir1Recruiting1
DB00073Rituximab1Active Not Recruiting1
DB05794Serelaxin1Completed1
DB00658Sevelamer1Completed1
DB00877Sirolimus1Completed1
DB09517Sodium ferric gluconate complex1Completed1
DB08816Ticagrelor1Completed1
DB00684Tobramycin1Recruiting1
DB12000Apabetalone1 / 2Not Yet Recruiting1
DB12849Clazakizumab1 / 2Recruiting1
DB06556Edifoligide1 / 2Terminated1
DB00095Efalizumab1 / 2Terminated1
DB14276Turmeric1 / 2Completed1
DB06151Acetylcysteine2Completed1
DB00087Alemtuzumab2Completed1
DB05024CTA0182Completed1
DB00531Cyclophosphamide2Completed1
DB00586Diclofenac2Terminated1
DB00016Erythropoietin2Completed2
DB00016Erythropoietin2Recruiting1
DB00800Fenoldopam2Completed1
DB00158Folic acid2Completed1
DB00028Human immunoglobulin G2Terminated1
DB01611Hydroxychloroquine2Terminated1
DB01592Iron2Completed1
DB06655Liraglutide2Withdrawn1
DB01283Lumiracoxib2Terminated1
DB00959Methylprednisolone2Completed1
DB00688Mycophenolate mofetil2Completed3
DB11133Omega-3 fatty acids2Completed1
DB08894Peginesatide2Completed5
DB08894Peginesatide2Terminated3
DB00635Prednisone2Completed1
DB00073Rituximab2Completed2
DB00360Sapropterin2Completed1
DB00658Sevelamer2Completed3
DB06371Siplizumab2Completed1
DB00877Sirolimus2Completed1
DB09153Sodium chloride2Completed1
DB05995Sotatercept2Completed1
DB12118Sotatercept2Completed1
DB14101Soy isoflavones2Completed1
DB11657Tabalumab2Completed1
DB00864Tacrolimus2Completed2
DB06212Tolvaptan2Completed3
DB06151Acetylcysteine2 / 3Unknown Status1
DB00126Ascorbic acid2 / 3Completed1
DB01109Heparin2 / 3Completed1
DB01109Heparin2 / 3Suspended1
DB00163Vitamin E2 / 3Completed1
DB06151Acetylcysteine3Completed1
DB11842Angiotensin II3Completed1
DB00098Antithymocyte immunoglobulin (rabbit)3Completed1
DB06681Belatacept3Completed1
DB06681Belatacept3Not Yet Recruiting1
DB00297Bupivacaine3Completed1
DB01012Cinacalcet3Completed1
DB01012Cinacalcet3Terminated1
DB00758Clopidogrel3Completed1
DB00091Cyclosporine3Completed1
DB09102Daclatasvir3Recruiting1
DB00111Daclizumab3Completed1
DB06779Dalteparin3Completed1
DB00012Darbepoetin alfa3Completed3
DB01234Dexamethasone3Completed1
DB00633Dexmedetomidine3Completed1
DB00016Erythropoietin3Completed6
DB00016Erythropoietin3Terminated1
DB01590Everolimus3Terminated1
DB00846Flurandrenolide3Completed1
DB01109Heparin3Completed1
DB01109Heparin3Unknown Status1
DB13886Human cytomegalovirus immune globulin3Completed1
DB01029Irbesartan3Completed1
DB01592Iron3Terminated1
DB06792Lanthanum carbonate3Completed4
DB06792Lanthanum carbonate3Terminated1
DB00683Midazolam3Completed1
DB00688Mycophenolate mofetil3Completed1
DB00627Niacin3Terminated1
DB02701Nicotinamide3Terminated1
DB08894Peginesatide3Completed4
DB00806Pentoxifylline3Completed1
DB06209Prasugrel3Completed1
DB00635Prednisone3Completed1
DB00178Ramipril3Completed1
DB00658Sevelamer3Completed2
DB00658Sevelamer3Terminated2
DB11080Silver nitrate3Completed1
DB00877Sirolimus3Active Not Recruiting1
DB09153Sodium chloride3Completed1
DB08934Sofosbuvir3Recruiting1
DB00052Somatotropin3Completed1
DB00864Tacrolimus3Completed1
DB12473Taurolidine3Completed1
DB00966Telmisartan3Completed1
DB00624Testosterone3Recruiting1
DB06273Tocilizumab3Recruiting1
DB06151Acetylcysteine4Unknown Status1
DB09278Activated charcoal4Unknown Status1
DB09026Aliskiren4Terminated1
DB00770Alprostadil4Unknown Status1
DB00381Amlodipine4Completed1
DB11842Angiotensin II4Recruiting1
DB00278Argatroban4Completed1
DB00074Basiliximab4Completed1
DB00146Calcifediol4Unknown Status1
DB13919Candesartan4Unknown Status1
DB06774Capsaicin4Unknown Status1
DB09301Chondroitin sulfate4Completed1
DB01012Cinacalcet4Completed1
DB00257Clotrimazole4Completed1
DB00091Cyclosporine4Completed2
DB00091Cyclosporine4Unknown Status1
DB09102Daclatasvir4Completed1
DB00111Daclizumab4Unknown Status1
DB00012Darbepoetin alfa4Completed1
DB13529Dobesilic acid4Recruiting1
DB06410Doxercalciferol4Completed1
DB11574Elbasvir4Withdrawn1
DB00584Enalapril4Unknown Status1
DB00700Eplerenone4Completed1
DB11624Epoetin delta4Terminated1
DB00016Erythropoietin4Completed3
DB01590Everolimus4Completed1
DB01590Everolimus4Recruiting1
DB14488Ferrous gluconate4Completed2
DB13257Ferrous sulfate anhydrous4Completed2
DB00158Folic acid4Completed1
DB13879Glecaprevir4Active Not Recruiting1
DB11575Grazoprevir4Withdrawn1
DB01109Heparin4Completed1
DB14455Influenza A virus A/California/7/2009 X-181 (H1N1) antigen (formaldehyde inactivated)4Completed1
DB10792Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated)4Completed1
DB14456Influenza B virus B/Brisbane/9/2014 antigen (formaldehyde inactivated)4Completed1
DB01306Insulin aspart4Completed1
DB01249Iodixanol4Completed1
DB01249Iodixanol4Unknown Status1
DB09156Iopromide4Completed1
DB09156Iopromide4Unknown Status1
DB01592Iron4Completed4
DB09146Iron sucrose4Completed1
DB06790Iron sucrose4Unknown Status1
DB09146Iron sucrose4Unknown Status1
DB04465Lactose4Completed1
DB06792Lanthanum carbonate4Completed1
DB08882Linagliptin4Completed1
DB00959Methylprednisolone4Completed1
DB00688Mycophenolate mofetil4Completed1
DB01024Mycophenolic acid4Completed1
DB01024Mycophenolic acid4Recruiting1
DB09220Nicorandil4Completed1
DB01115Nifedipine4Completed1
DB00646Nystatin4Completed1
DB09539Omega-3-acid ethyl esters4Completed1
DB00910Paricalcitol4Completed1
DB00910Paricalcitol4Unknown Status1
DB09263Patiromer4Completed1
DB00806Pentoxifylline4Recruiting1
DB01022Phylloquinone4Recruiting1
DB13878Pibrentasvir4Active Not Recruiting1
DB00635Prednisone4Completed1
DB00635Prednisone4Recruiting1
DB06228Rivaroxaban4Completed1
DB00877Sirolimus4Completed1
DB00877Sirolimus4Unknown Status1
DB09517Sodium ferric gluconate complex4Completed2
DB08934Sofosbuvir4Completed1
DB08934Sofosbuvir4Withdrawn1
DB00052Somatotropin4Completed1
DB06417Somatotropin4Completed1
DB00421Spironolactone4Completed2
DB00421Spironolactone4Unknown Status1
DB06206Sugammadex4Completed1
DB00864Tacrolimus4Completed3
DB00864Tacrolimus4Recruiting1
DB00864Tacrolimus4Unknown Status1
DB14520Tetraferric tricitrate decahydrate4Completed1
DB06822Tinzaparin4Completed1
DB01344Tolevamer4Completed1
DB09270Ubidecarenone4Completed1
DB11094Vitamin D4Completed2
DB06151AcetylcysteineNot AvailableTerminated1
DB00630Alendronic acidNot AvailableRecruiting1
DB00126Ascorbic acidNot AvailableUnknown Status1
DB00993AzathioprineNot AvailableCompleted1
DB00542BenazeprilNot AvailableTerminated1
DB15200BixalomerNot AvailableCompleted1
DB06724Calcium carbonateNot AvailableWithdrawn1
DB01012CinacalcetNot AvailableRecruiting1
DB00091CyclosporineNot AvailableCompleted1
DB00012Darbepoetin alfaNot AvailableCompleted2
DB11624Epoetin deltaNot AvailableTerminated1
DB00016ErythropoietinNot AvailableCompleted1
DB00016ErythropoietinNot AvailableUnknown Status1
DB00695FurosemideNot AvailableCompleted1
DB05059ILY101Not AvailableCompleted1
DB06792Lanthanum carbonateNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00742MannitolNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting2
DB00688Mycophenolate mofetilNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableTerminated1
DB03783PhenacetinNot AvailableCompleted1
DB00296RopivacaineNot AvailableCompleted2
DB01001SalbutamolNot AvailableUnknown Status1
DB00658SevelamerNot AvailableWithdrawn1
DB00641SimvastatinNot AvailableCompleted1
DB00052SomatotropinNot AvailableCompleted1
DB00864TacrolimusNot AvailableCompleted1
DB00706TamsulosinNot AvailableUnknown Status1
DB06285TeriparatideNot AvailableRecruiting1
DB00495ZidovudineNot AvailableCompleted1
DB01593ZincNot AvailableCompleted1
DB01593ZincNot AvailableTerminated1