Coronary Heart Disease (CHD)

Also known as: Coronary heart disease / Coronary Heart Diseases / Coronary Disease / Coronary artery disease NOS / Disorder of coronary artery / Coronary artery disease / CAD / Coronary artery disorders / Disorder coronary artery / Coronary artery disorder / Coronary artery disorder (NOS) / Disease coronary artery / Atherosclerotic cardiovascular disease

DrugDrug NameDrug Description
DB01095FluvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB01241GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
DB00227LovastatinAn HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
DB00175PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
DrugDrug NameTargetType
DB01095Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01095FluvastatinCytochrome P450 2C9enzyme
DB01095FluvastatinCytochrome P450 3A4enzyme
DB01095FluvastatinCytochrome P450 2C8enzyme
DB01095FluvastatinCytochrome P450 2D6enzyme
DB01095FluvastatinCytochrome P450 2C19enzyme
DB01095FluvastatinCytochrome P450 1A1enzyme
DB01095FluvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01095FluvastatinSolute carrier family 15 member 1transporter
DB01095FluvastatinCytochrome P450 3A5enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01095FluvastatinCanalicular multispecific organic anion transporter 1transporter
DB01095FluvastatinCytochrome P450 2B6enzyme
DB01095FluvastatinHistone deacetylase 2target
DB01241GemfibrozilPeroxisome proliferator-activated receptor alphatarget
DB01241GemfibrozilCytochrome P450 2C9enzyme
DB01241GemfibrozilCytochrome P450 2C8enzyme
DB01241GemfibrozilCytochrome P450 1A2enzyme
DB01241GemfibrozilCytochrome P450 2C19enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
DB01241GemfibrozilCytochrome P450 3A4enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B1target
DB01241GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
DB01241GemfibrozilSerum albumincarrier
DB01241GemfibrozilSolute carrier family 22 member 8target
DB01241GemfibrozilSolute carrier organic anion transporter family member 2B1target
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B3target
DB00227Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00227LovastatinCytochrome P450 3A4enzyme
DB00227LovastatinCytochrome P450 2C8enzyme
DB00227LovastatinIntegrin alpha-Ltarget
DB00227LovastatinHistone deacetylase 2target
DB00227LovastatinSerum paraoxonase/lactonase 3enzyme
DB00227LovastatinP-glycoprotein 1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1A2transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B1transporter
DB00227LovastatinUDP-glucuronosyltransferase 1-1enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-3enzyme
DB00227LovastatinUDP-glucuronosyltransferase 2B7enzyme
DB00227LovastatinCanalicular multispecific organic anion transporter 1transporter
DB00227LovastatinBile salt export pumptransporter
DB00227LovastatinSerum albumincarrier
DB00227LovastatinCytochrome P450 2C19enzyme
DB00227LovastatinSolute carrier organic anion transporter family member 2B1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B3transporter
DB00175Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00175PravastatinSolute carrier organic anion transporter family member 2B1transporter
DB00175PravastatinP-glycoprotein 1transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1A2transporter
DB00175PravastatinSolute carrier family 22 member 6transporter
DB00175PravastatinSolute carrier family 22 member 8transporter
DB00175PravastatinCanalicular multispecific organic anion transporter 1transporter
DB00175PravastatinSolute carrier family 22 member 11transporter
DB00175PravastatinATP-binding cassette sub-family G member 2transporter
DB00175PravastatinSolute carrier family 22 member 7transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B1transporter
DB00175PravastatinMonocarboxylate transporter 1transporter
DB00175PravastatinBile salt export pumptransporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B3transporter
DB00175PravastatinHistone deacetylase 2target
DrugDrug NamePhaseStatusCount
DB00973Ezetimibe0Completed1
DB09302Alirocumab1Active Not Recruiting1
DB15094Anfibatide1Completed1
DB01076Atorvastatin1Completed1
DB00973Ezetimibe1Completed1
DB05760Telcagepant1Completed1
DB12228Telcagepant1Completed1
DB00126Ascorbic acid2Completed1
DB00207Azithromycin2Recruiting1
DB06755Beta carotene2Completed1
DB00006Bivalirudin2Not Yet Recruiting1
DB01432Cholestyramine2Completed1
DB00115Cyanocobalamin2Completed1
DB06695Dabigatran etexilate2Completed1
DB12181Dalcetrapib2Completed4
DB12140Dilmapimod2Completed1
DB00254Doxycycline2Recruiting1
DB00063Eptifibatide2Completed1
DB05869Ethyl pyruvate2Terminated1
DB05599Fibroblast growth factor-12Not Yet Recruiting1
DB00158Folic acid2Completed1
DB00569Fondaparinux2Withdrawn1
DB01241Gemfibrozil2Completed1
DB01645Genistein2Completed1
DB01109Heparin2Completed1
DB01109Heparin2Withdrawn1
DB00160L-Alanine2Completed1
DB00130L-Glutamine2Completed1
DB00922Levosimendan2Completed1
DB06655Liraglutide2Completed1
DB00227Lovastatin2Completed1
DB14513Magnesium2Completed1
DB04899Nesiritide2Completed1
DB00627Niacin2Completed1
DB00435Nitric Oxide2Completed1
DB11133Omega-3 fatty acids2Completed1
DB06635Otamixaban2Completed1
DB11839PZ-1282Completed1
DB12971Pactimibe2Completed1
DB00175Pravastatin2Completed1
DB00175Pravastatin2Recruiting1
DB00165Pyridoxine2Completed1
DB00178Ramipril2Completed1
DB05553Regrelor2Terminated1
DB00615Rifabutin2Recruiting1
DB01098Rosuvastatin2Recruiting1
DB09153Sodium chloride2Recruiting1
DB13946Testosterone undecanoate2Completed1
DB06273Tocilizumab2Recruiting1
DB00163Vitamin E2Completed1
DB05692Vorapaxar2Completed1
DB09030Vorapaxar2Completed1
DB06552rNAPc22Completed1
DB00945Acetylsalicylic acid2 / 3Completed1
DB00594Amiloride2 / 3Completed1
DB00758Clopidogrel2 / 3Completed1
DB00286Conjugated estrogens2 / 3Completed1
DB00584Enalapril2 / 3Recruiting1
DB00158Folic acid2 / 3Recruiting1
DB00603Medroxyprogesterone acetate2 / 3Completed1
DB14049Nitrate2 / 3Completed1
DB00284Acarbose3Completed1
DB00945Acetylsalicylic acid3Completed5
DB00945Acetylsalicylic acid3Recruiting1
DB00009Alteplase3Completed3
DB00381Amlodipine3Completed2
DB06630Anacetrapib3Completed1
DB11842Angiotensin II3Completed2
DB00126Ascorbic acid3Completed1
DB00335Atenolol3Completed1
DB01076Atorvastatin3Completed7
DB01076Atorvastatin3Terminated1
DB00207Azithromycin3Completed1
DB00542Benazepril3Completed1
DB00201Caffeine3Completed1
DB01373Calcium3Completed2
DB00796Candesartan cilexetil3Completed1
DB01136Carvedilol3Completed1
DB00310Chlorthalidone3Completed2
DB01432Cholestyramine3Completed3
DB00636Clofibrate3Completed1
DB00758Clopidogrel3Withdrawn1
DB00375Colestipol3Completed2
DB00286Conjugated estrogens3Completed3
DB12181Dalcetrapib3Completed2
DB00509Dextrothyroxine3Completed1
DB00343Diltiazem3Completed2
DB00975Dipyridamole3Completed2
DB00841Dobutamine3Completed1
DB00590Doxazosin3Completed1
DB00584Enalapril3Completed1
DB01228Encainide3Completed1
DB00783Estradiol3Completed7
DB09303Evolocumab3Recruiting1
DB00973Ezetimibe3Completed11
DB01023Felodipine3Completed1
DB01039Fenofibrate3Completed1
DB13873Fenofibric acid3Completed6
DB01195Flecainide3Completed1
DB00695Furosemide3Completed1
DB01241Gemfibrozil3Completed1
DB00222Glimepiride3Completed1
DB01109Heparin3Completed1
DB14740Hyaluronidase3Completed1
DB01275Hydralazine3Completed1
DB00999Hydrochlorothiazide3Completed1
DB01306Insulin aspart3Completed1
DB01307Insulin detemir3Completed1
DB00047Insulin glargine3Completed1
DB00030Insulin human3Completed1
DB00883Isosorbide dinitrate3Completed1
DB09083Ivabradine3Completed1
DB11629Laropiprant3Completed1
DB00722Lisinopril3Completed2
DB00227Lovastatin3Completed2
DB14513Magnesium3Completed1
DB00603Medroxyprogesterone acetate3Completed4
DB00331Metformin3Completed1
DB00264Metoprolol3Completed1
DB05528Mipomersen3Completed2
DB00680Moricizine3Completed1
DB04899Nesiritide3Withdrawn1
DB00627Niacin3Completed5
DB00627Niacin3Terminated1
DB01115Nifedipine3Completed1
DB00727Nitroglycerin3Completed1
DB11133Omega-3 fatty acids3Completed1
DB09539Omega-3-acid ethyl esters3Completed1
DB01132Pioglitazone3Completed1
DB08860Pitavastatin3Completed1
DB14500Potassium3Completed1
DB00175Pravastatin3Completed1
DB00396Progesterone3Completed3
DB00571Propranolol3Completed2
DB00178Ramipril3Completed1
DB00912Repaglinide3Completed1
DB00206Reserpine3Completed1
DB00412Rosiglitazone3Completed1
DB01098Rosuvastatin3Completed5
DB01098Rosuvastatin3Unknown Status1
DB01236Sevoflurane3Completed1
DB00641Simvastatin3Completed9
DB00641Simvastatin3Terminated1
DB00086Streptokinase3Completed2
DB00675Tamoxifen3Completed1
DB01162Terazosin3Completed1
DB08816Ticagrelor3Withdrawn1
DB06281Torcetrapib3Completed1
DB06281Torcetrapib3Terminated1
DB00384Triamterene3Completed1
DB00177Valsartan3Completed1
DB11094Vitamin D3Completed1
DB00163Vitamin E3Completed3
DB00682Warfarin3Completed1
DB13453Xenon3Completed1
DB00054Abciximab4Completed3
DB00054Abciximab4Terminated1
DB00284Acarbose4Active Not Recruiting1
DB00945Acetylsalicylic acid4Active Not Recruiting2
DB00945Acetylsalicylic acid4Completed8
DB00945Acetylsalicylic acid4Not Yet Recruiting1
DB12417Anagliptin4Completed1
DB01076Atorvastatin4Completed7
DB01076Atorvastatin4Terminated1
DB01076Atorvastatin4Unknown Status2
DB00006Bivalirudin4Completed2
DB00006Bivalirudin4Not Yet Recruiting1
DB00006Bivalirudin4Withdrawn1
DB01136Carvedilol4Unknown Status1
DB00758Clopidogrel4Active Not Recruiting2
DB00758Clopidogrel4Completed8
DB00758Clopidogrel4Not Yet Recruiting2
DB00758Clopidogrel4Recruiting1
DB00758Clopidogrel4Unknown Status2
DB00758Clopidogrel4Withdrawn1
DB14726Dabigatran4Completed1
DB14726Dabigatran4Terminated1
DB14726Dabigatran4Withdrawn1
DB06695Dabigatran etexilate4Completed1
DB06695Dabigatran etexilate4Terminated1
DB06695Dabigatran etexilate4Withdrawn1
DB01189Desflurane4Not Yet Recruiting1
DB00975Dipyridamole4Completed1
DB09038Empagliflozin4Recruiting2
DB01225Enoxaparin4Completed1
DB01175Escitalopram4Completed1
DB00973Ezetimibe4Completed5
DB00973Ezetimibe4Unknown Status1
DB00927Famotidine4Completed1
DB01039Fenofibrate4Completed1
DB01095Fluvastatin4Completed2
DB01095Fluvastatin4Unknown Status1
DB01109Heparin4Completed2
DB01109Heparin4Not Yet Recruiting1
DB09106Hydroxyethyl Starch4Completed1
DB00753Isoflurane4Not Yet Recruiting1
DB00883Isosorbide dinitrate4Completed1
DB09083Ivabradine4Unknown Status1
DB04398Lactic acid4Completed1
DB11629Laropiprant4Completed1
DB00627Niacin4Completed3
DB09220Nicorandil4Completed1
DB09220Nicorandil4Recruiting1
DB00184Nicotine4Completed1
DB00338Omeprazole4Completed1
DB00213Pantoprazole4Completed1
DB00946Phenprocoumon4Terminated1
DB00946Phenprocoumon4Withdrawn1
DB09528Phylloquinone4Withdrawn1
DB01132Pioglitazone4Completed1
DB01132Pioglitazone4Unknown Status1
DB08860Pitavastatin4Completed2
DB06209Prasugrel4Completed1
DB06209Prasugrel4Unknown Status1
DB00175Pravastatin4Completed1
DB00175Pravastatin4Unknown Status1
DB00818Propofol4Not Yet Recruiting1
DB00178Ramipril4Unknown Status1
DB06228Rivaroxaban4Withdrawn1
DB01098Rosuvastatin4Completed2
DB01098Rosuvastatin4Not Yet Recruiting1
DB01098Rosuvastatin4Recruiting1
DB01098Rosuvastatin4Unknown Status1
DB01236Sevoflurane4Not Yet Recruiting1
DB00641Simvastatin4Completed5
DB00877Sirolimus4Completed1
DB01261Sitagliptin4Completed1
DB01261Sitagliptin4Recruiting1
DB00966Telmisartan4Unknown Status1
DB11300Thrombin4Withdrawn1
DB08816Ticagrelor4Completed1
DB08816Ticagrelor4Recruiting1
DB08816Ticagrelor4Unknown Status2
DB00775Tirofiban4Terminated1
DB09069Trimetazidine4Not Yet Recruiting1
DB01273Varenicline4Completed1
DB00945Acetylsalicylic acidNot AvailableCompleted4
DB00945Acetylsalicylic acidNot AvailableWithdrawn1
DB00381AmlodipineNot AvailableCompleted1
DB00381AmlodipineNot AvailableWithdrawn1
DB11842Angiotensin IINot AvailableCompleted1
DB00335AtenololNot AvailableCompleted1
DB00335AtenololNot AvailableWithdrawn1
DB12054BQ-123Not AvailableCompleted1
DB00006BivalirudinNot AvailableRecruiting1
DB01136CarvedilolNot AvailableCompleted1
DB00310ChlorthalidoneNot AvailableCompleted1
DB01166CilostazolNot AvailableCompleted1
DB00636ClofibrateNot AvailableCompleted1
DB00758ClopidogrelNot AvailableCompleted4
DB06311DarapladibNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableCompleted1
DB00509DextrothyroxineNot AvailableCompleted1
DB00590DoxazosinNot AvailableCompleted1
DB00584EnalaprilNot AvailableWithdrawn1
DB12652Endothelin-1Not AvailableCompleted1
DB01225EnoxaparinNot AvailableCompleted1
DB00783EstradiolNot AvailableCompleted2
DB00783EstradiolNot AvailableTerminated1
DB00977EthinylestradiolNot AvailableCompleted1
DB01276ExenatideNot AvailableRecruiting1
DB00973EzetimibeNot AvailableActive Not Recruiting1
DB00973EzetimibeNot AvailableCompleted1
DB00973EzetimibeNot AvailableRecruiting1
DB00222GlimepirideNot AvailableActive Not Recruiting1
DB00062Human Serum AlbuminNot AvailableRecruiting1
DB00999HydrochlorothiazideNot AvailableCompleted1
DB01064IsoprenalineNot AvailableCompleted1
DB01020Isosorbide mononitrateNot AvailableWithdrawn1
DB00007LeuprolideNot AvailableCompleted1
DB00367LevonorgestrelNot AvailableCompleted1
DB00722LisinoprilNot AvailableCompleted2
DB00331MetforminNot AvailableActive Not Recruiting1
DB00264MetoprololNot AvailableCompleted2
DB00471MontelukastNot AvailableCompleted1
DB00627NiacinNot AvailableCompleted2
DB00727NitroglycerinNot AvailableWithdrawn1
DB09140OxygenNot AvailableRecruiting1
DB14500PotassiumNot AvailableCompleted1
DB00396ProgesteroneNot AvailableCompleted1
DB00571PropranololNot AvailableCompleted1
DB06213RegadenosonNot AvailableCompleted1
DB06213RegadenosonNot AvailableRecruiting1
DB01098RosuvastatinNot AvailableCompleted1
DB00641SimvastatinNot AvailableCompleted1
DB00641SimvastatinNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableCompleted1
DB08816TicagrelorNot AvailableCompleted1
DB00661VerapamilNot AvailableCompleted1
DB04878VogliboseNot AvailableUnknown Status1