End Stage Renal Disease (ESRD)

Also known as: End Stage Renal Diseases / End Stage Renal Disease / Chronic uremia / Renal failure chronic / Chronic renal failure / Kidney failure chronic / Kidney Failure, Chronic / End stage renal failure / Chronic renal disease

DrugDrug NameDrug Description
DB08907CanagliflozinA sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
DB06792Lanthanum carbonateA phosphate binder indicated for the reduction of serum phosphate in patients with end stage renal disease.
DB00583LevocarnitineA quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia.
DrugDrug NameTargetType
DB08907CanagliflozinUDP-glucuronosyltransferase 1-9enzyme
DB08907CanagliflozinUDP-glucuronosyltransferase 2B4enzyme
DB08907CanagliflozinCytochrome P450 3A4enzyme
DB08907CanagliflozinSodium/glucose cotransporter 2target
DB08907CanagliflozinP-glycoprotein 1transporter
DB08907CanagliflozinCanalicular multispecific organic anion transporter 1transporter
DB08907CanagliflozinAlpha-1-acid glycoprotein 1carrier
DB08907CanagliflozinATP-binding cassette sub-family G member 2transporter
DB06792Lanthanum carbonatePhosphatetarget
DB00583LevocarnitineCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB00583LevocarnitineSolute carrier family 22 member 4target
DB00583LevocarnitineSolute carrier family 22 member 5target
DB00583LevocarnitineCarnitine O-acetyltransferasetarget
DB00583LevocarnitineMitochondrial carnitine/acylcarnitine carrier protein CACLtarget
DB00583LevocarnitineMitochondrial carnitine/acylcarnitine carrier proteintarget
DB00583LevocarnitinePeroxisomal carnitine O-octanoyltransferasetarget
DB00583LevocarnitineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
DB00583LevocarnitineSolute carrier family 22 member 4transporter
DB00583LevocarnitineSolute carrier organic anion transporter family member 1B1transporter
DB00583LevocarnitineSolute carrier family 22 member 5transporter
DB00583LevocarnitineSolute carrier family 22 member 16transporter
DB00583LevocarnitineSolute carrier family 22 member 8transporter
DB00583LevocarnitineXanthine dehydrogenase/oxidasetarget
DB00583LevocarnitineLiver carboxylesterase 1target
DB00583LevocarnitineMyeloperoxidasetarget
DrugDrug NamePhaseStatusCount
DB00112Bevacizumab0Recruiting1
DB01220Rifaximin0Withdrawn1
DB09026Aliskiren1Completed1
DB06605Apixaban1Completed1
DB08889Carfilzomib1Active Not Recruiting1
DB01285Corticotropin1Terminated1
DB09547Corticotropin1Terminated1
DB00531Cyclophosphamide1Completed2
DB00091Cyclosporine1Completed1
DB00080Daptomycin1Completed2
DB06262Droxidopa1Withdrawn1
DB12329Eravacycline1Completed1
DB13995Ferric pyrophosphate citrate1Completed2
DB01109Heparin1Completed1
DB06792Lanthanum carbonate1Completed1
DB01024Mycophenolic acid1Completed1
DB00198Oseltamivir1Completed1
DB06228Rivaroxaban1Completed1
DB00268Ropinirole1Completed1
DB05794Serelaxin1Completed1
DB00052Somatotropin1Completed1
DB00864Tacrolimus1Completed1
DB06402Telavancin1Completed1
DB09499Thiosulfuric acid1Not Yet Recruiting1
DB00560Tigecycline1Completed1
DB15171Tirzepatide1Completed1
DB08895Tofacitinib1Completed1
DB11876Alanyl glutamine1 / 2Terminated1
DB00087Alemtuzumab1 / 2Unknown Status1
DB00098Antithymocyte immunoglobulin (rabbit)1 / 2Unknown Status1
DB12849Clazakizumab1 / 2Recruiting1
DB00091Cyclosporine1 / 2Unknown Status1
DB11574Elbasvir1 / 2Active Not Recruiting1
DB01590Everolimus1 / 2Unknown Status1
DB13995Ferric pyrophosphate citrate1 / 2Completed2
DB13995Ferric pyrophosphate citrate1 / 2Not Yet Recruiting2
DB13879Glecaprevir1 / 2Active Not Recruiting1
DB11575Grazoprevir1 / 2Active Not Recruiting1
DB01109Heparin1 / 2Not Yet Recruiting1
DB06404Human C1-esterase inhibitor1 / 2Completed1
DB00028Human immunoglobulin G1 / 2Completed1
DB12578Lexaptepid Pegol1 / 2Completed1
DB00688Mycophenolate mofetil1 / 2Unknown Status2
DB13878Pibrentasvir1 / 2Active Not Recruiting1
DB00073Rituximab1 / 2Active Not Recruiting1
DB00073Rituximab1 / 2Completed1
DB06371Siplizumab1 / 2Active Not Recruiting1
DB00877Sirolimus1 / 2Unknown Status1
DB00864Tacrolimus1 / 2Unknown Status2
DB08816Ticagrelor1 / 2Recruiting1
DB06273Tocilizumab1 / 2Completed1
DB00026Anakinra2Active Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB05983Bardoxolone methyl2Withdrawn1
DB00074Basiliximab2Terminated1
DB00188Bortezomib2Unknown Status1
DB00136Calcitriol2Active Not Recruiting1
DB00136Calcitriol2Completed1
DB06724Calcium carbonate2Completed1
DB01164Calcium chloride2Not Yet Recruiting1
DB00169Cholecalciferol2Active Not Recruiting1
DB00169Cholecalciferol2Completed1
DB01012Cinacalcet2Completed3
DB09110Coenzyme M2Completed1
DB01003Cromoglicic acid2Completed1
DB00091Cyclosporine2Terminated1
DB09102Daclatasvir2Withdrawn1
DB00055Drotrecogin alfa2Completed1
DB01257Eculizumab2Active Not Recruiting1
DB01257Eculizumab2Completed1
DB09038Empagliflozin2Recruiting1
DB00303Ertapenem2Completed1
DB00016Erythropoietin2Completed2
DB00016Erythropoietin2Terminated1
DB01175Escitalopram2Terminated1
DB00005Etanercept2Terminated1
DB12865Etelcalcetide2Recruiting1
DB09147Ferric pyrophosphate2Completed1
DB00996Gabapentin2Suspended1
DB00702Icodextrin2Not Yet Recruiting1
DB00702Icodextrin2Unknown Status1
DB01592Iron2Completed1
DB09570Ixazomib2Recruiting1
DB04398Lactic acid2Not Yet Recruiting1
DB00583Levocarnitine2Completed3
DB00583Levocarnitine2Not Yet Recruiting1
DB00583Levocarnitine2Recruiting1
DB00583Levocarnitine2Withdrawn1
DB00166Lipoic acid2Completed1
DB09407Magnesium chloride2Not Yet Recruiting1
DB00959Methylprednisolone2Terminated1
DB14375Milk thistle2Completed1
DB00910Paricalcitol2Completed1
DB09263Patiromer2Active Not Recruiting1
DB00806Pentoxifylline2Terminated1
DB00635Prednisone2Terminated1
DB00073Rituximab2Unknown Status1
DB00268Ropinirole2Suspended1
DB04847Roxadustat2Completed1
DB06290Simeprevir2Withdrawn1
DB00877Sirolimus2Recruiting1
DB00877Sirolimus2Terminated1
DB09153Sodium chloride2Not Yet Recruiting1
DB08934Sofosbuvir2Not Yet Recruiting1
DB00052Somatotropin2Completed3
DB00421Spironolactone2Completed1
DB01015Sulfamethoxazole2Terminated1
DB00864Tacrolimus2Terminated1
DB11761Tenapanor2Completed1
DB14520Tetraferric tricitrate decahydrate2Completed2
DB00277Theophylline2Recruiting1
DB11300Thrombin2Recruiting1
DB04900Thymalfasin2Completed1
DB00440Trimethoprim2Terminated1
DB12255Vadadustat2Completed1
DB00512Vancomycin2Completed1
DB00067Vasopressin2Completed1
DB11613Velpatasvir2Not Yet Recruiting1
DB00163Vitamin E2Completed1
DB11195Xylitol2Not Yet Recruiting1
DB11195Xylitol2Recruiting1
DB00074Basiliximab2 / 3Terminated1
DB00169Cholecalciferol2 / 3Recruiting1
DB00028Human immunoglobulin G2 / 3Completed1
DB01065Melatonin2 / 3Recruiting1
DB14936Menaquinone 62 / 3Recruiting1
DB00688Mycophenolate mofetil2 / 3Completed1
DB01024Mycophenolic acid2 / 3Completed1
DB04847Roxadustat2 / 3Completed1
DB00864Tacrolimus2 / 3Recruiting1
DB11094Vitamin D2 / 3Recruiting1
DB06151Acetylcysteine3Completed1
DB00993Azathioprine3Recruiting1
DB01164Calcium chloride3Completed1
DB01012Cinacalcet3Completed4
DB00091Cyclosporine3Terminated1
DB00012Darbepoetin alfa3Completed2
DB09183Dasabuvir3Completed1
DB00700Eplerenone3Recruiting1
DB00016Erythropoietin3Completed1
DB09147Ferric pyrophosphate3Completed1
DB13995Ferric pyrophosphate citrate3Not Yet Recruiting1
DB00996Gabapentin3Recruiting1
DB01109Heparin3Unknown Status1
DB11627Hepatitis B Vaccine (Recombinant)3Completed1
DB00028Human immunoglobulin G3Completed1
DB00702Icodextrin3Completed1
DB01029Irbesartan3Completed1
DB04398Lactic acid3Completed1
DB09407Magnesium chloride3Completed1
DB00688Mycophenolate mofetil3Recruiting1
DB09296Ombitasvir3Completed1
DB00910Paricalcitol3Completed2
DB09297Paritaprevir3Completed1
DB00175Pravastatin3Completed1
DB14646Prednisone acetate3Recruiting1
DB00811Ribavirin3Completed1
DB00503Ritonavir3Completed1
DB00073Rituximab3Recruiting1
DB00268Ropinirole3Recruiting1
DB05271Rotigotine3Completed1
DB04847Roxadustat3Completed1
DB01104Sertraline3Completed1
DB00658Sevelamer3Completed1
DB00658Sevelamer3Recruiting1
DB00877Sirolimus3Active Not Recruiting1
DB00877Sirolimus3Terminated1
DB09153Sodium chloride3Completed1
DB00052Somatotropin3Terminated1
DB00421Spironolactone3Completed1
DB06271Sulodexide3Active Not Recruiting1
DB06271Sulodexide3Recruiting1
DB00864Tacrolimus3Recruiting1
DB00864Tacrolimus3Terminated1
DB14520Tetraferric tricitrate decahydrate3Completed3
DB14520Tetraferric tricitrate decahydrate3Recruiting1
DB00656Trazodone3Recruiting1
DB00682Warfarin3Completed1
DB06151Acetylcysteine4Unknown Status1
DB00945Acetylsalicylic acid4Withdrawn1
DB00087Alemtuzumab4Completed1
DB00630Alendronic acid4Completed1
DB01436Alfacalcidol4Completed1
DB09026Aliskiren4Unknown Status1
DB00437Allopurinol4Completed1
DB00098Antithymocyte immunoglobulin (rabbit)4Completed4
DB00098Antithymocyte immunoglobulin (rabbit)4Withdrawn1
DB06605Apixaban4Completed2
DB00626Bacitracin4Completed1
DB00074Basiliximab4Completed1
DB06681Belatacept4Withdrawn1
DB08873Boceprevir4Unknown Status1
DB01156Bupropion4Terminated1
DB00136Calcitriol4Completed1
DB01197Captopril4Completed1
DB01012Cinacalcet4Completed2
DB00758Clopidogrel4Recruiting1
DB09877Corynebacterium diphtheriae4Completed1
DB00091Cyclosporine4Completed3
DB00111Daclizumab4Completed1
DB00012Darbepoetin alfa4Completed1
DB01189Desflurane4Completed2
DB01234Dexamethasone4Withdrawn1
DB00843Donepezil4Completed1
DB11574Elbasvir4Completed1
DB00303Ertapenem4Completed1
DB01590Everolimus4Completed1
DB00472Fluoxetine4Terminated1
DB00695Furosemide4Recruiting1
DB13879Glecaprevir4Active Not Recruiting1
DB11575Grazoprevir4Completed1
DB01109Heparin4Active Not Recruiting1
DB13886Human cytomegalovirus immune globulin4Completed1
DB00028Human immunoglobulin G4Completed1
DB00999Hydrochlorothiazide4Suspended1
DB00030Insulin human4Recruiting1
DB00034Interferon alfa-2a, Recombinant4Completed1
DB06655Liraglutide4Completed1
DB00678Losartan4Not Yet Recruiting1
DB00678Losartan4Suspended1
DB00959Methylprednisolone4Completed2
DB12952Methylprednisone4Completed1
DB00410Mupirocin4Completed1
DB00688Mycophenolate mofetil4Completed4
DB01024Mycophenolic acid4Completed4
DB01024Mycophenolic acid4Withdrawn1
DB09220Nicorandil4Active Not Recruiting1
DB09296Ombitasvir4Completed1
DB00213Pantoprazole4Completed1
DB00910Paricalcitol4Completed1
DB09297Paritaprevir4Completed1
DB09263Patiromer4Recruiting1
DB00008Peginterferon alfa-2a4Completed1
DB00022Peginterferon alfa-2b4Unknown Status1
DB00806Pentoxifylline4Completed1
DB13878Pibrentasvir4Active Not Recruiting1
DB01132Pioglitazone4Completed1
DB00781Polymyxin B4Completed1
DB00635Prednisone4Completed2
DB00635Prednisone4Withdrawn1
DB00818Propofol4Completed2
DB00818Propofol4Recruiting1
DB00243Ranolazine4Completed1
DB00811Ribavirin4Completed2
DB00811Ribavirin4Unknown Status1
DB00503Ritonavir4Completed1
DB00658Sevelamer4Active Not Recruiting1
DB00877Sirolimus4Completed1
DB00877Sirolimus4Unknown Status1
DB01261Sitagliptin4Terminated1
DB01390Sodium bicarbonate4Active Not Recruiting1
DB01390Sodium bicarbonate4Completed2
DB08934Sofosbuvir4Completed1
DB00421Spironolactone4Not Yet Recruiting1
DB00421Spironolactone4Withdrawn2
DB10319Streptococcus pneumoniae type 1 capsular polysaccharide antigen4Completed1
DB10332Streptococcus pneumoniae type 14 capsular polysaccharide antigen4Completed1
DB10335Streptococcus pneumoniae type 18c capsular polysaccharide antigen4Completed1
DB10337Streptococcus pneumoniae type 19a capsular polysaccharide antigen4Completed1
DB10336Streptococcus pneumoniae type 19f capsular polysaccharide antigen4Completed1
DB10340Streptococcus pneumoniae type 23f capsular polysaccharide antigen4Completed1
DB10321Streptococcus pneumoniae type 3 capsular polysaccharide antigen4Completed1
DB10322Streptococcus pneumoniae type 4 capsular polysaccharide antigen4Completed1
DB10323Streptococcus pneumoniae type 5 capsular polysaccharide antigen4Completed1
DB10296Streptococcus pneumoniae type 6a capsular polysaccharide diphtheria crm197 protein conjugate antigen4Completed1
DB10324Streptococcus pneumoniae type 6b capsular polysaccharide antigen4Completed1
DB10325Streptococcus pneumoniae type 7f capsular polysaccharide antigen4Completed1
DB10328Streptococcus pneumoniae type 9v capsular polysaccharide antigen4Completed1
DB00864Tacrolimus4Active Not Recruiting1
DB00864Tacrolimus4Completed7
DB00864Tacrolimus4Withdrawn1
DB06402Telavancin4Completed1
DB00966Telmisartan4Completed1
DB11761Tenapanor4Active Not Recruiting1
DB14520Tetraferric tricitrate decahydrate4Active Not Recruiting1
DB14520Tetraferric tricitrate decahydrate4Completed1
DB14520Tetraferric tricitrate decahydrate4Recruiting1
DB08816Ticagrelor4Recruiting1
DB11251Tocopherol4Completed1
DB11094Vitamin D4Completed1
DB00682Warfarin4Completed1
DB00682Warfarin4Recruiting1
DB00026AnakinraNot AvailableCompleted1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB01076AtorvastatinNot AvailableCompleted1
DB00993AzathioprineNot AvailableActive Not Recruiting1
DB06681BelataceptNot AvailableCompleted1
DB08873BoceprevirNot AvailableWithdrawn1
DB00136CalcitriolNot AvailableTerminated1
DB01373CalciumNot AvailableCompleted1
DB06724Calcium carbonateNot AvailableCompleted1
DB06724Calcium carbonateNot AvailableWithdrawn1
DB01164Calcium chlorideNot AvailableCompleted1
DB01327CefazolinNot AvailableEnrolling by Invitation1
DB00438CeftazidimeNot AvailableEnrolling by Invitation1
DB00169CholecalciferolNot AvailableCompleted4
DB00537CiprofloxacinNot AvailableEnrolling by Invitation1
DB00115CyanocobalaminNot AvailableCompleted1
DB00091CyclosporineNot AvailableActive Not Recruiting1
DB00111DaclizumabNot AvailableCompleted2
DB00700EplerenoneNot AvailableCompleted1
DB00153ErgocalciferolNot AvailableCompleted2
DB00016ErythropoietinNot AvailableCompleted1
DB00016ErythropoietinNot AvailableTerminated1
DB01590EverolimusNot AvailableRecruiting1
DB09147Ferric pyrophosphateNot AvailableTerminated1
DB00158Folic acidNot AvailableCompleted1
DB01004GanciclovirNot AvailableCompleted1
DB00798GentamicinNot AvailableCompleted1
DB01109HeparinNot AvailableRecruiting1
DB00702IcodextrinNot AvailableCompleted2
DB05258Interferon alfaNot AvailableWithdrawn1
DB01592IronNot AvailableTerminated1
DB04398Lactic acidNot AvailableCompleted1
DB06792Lanthanum carbonateNot AvailableCompleted2
DB01137LevofloxacinNot AvailableCompleted1
DB09407Magnesium chlorideNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableActive Not Recruiting1
DB00688Mycophenolate mofetilNot AvailableCompleted1
DB01024Mycophenolic acidNot AvailableActive Not Recruiting1
DB08804Nandrolone decanoateNot AvailableCompleted1
DB00727NitroglycerinNot AvailableTerminated1
DB00910ParicalcitolNot AvailableTerminated1
DB00008Peginterferon alfa-2aNot AvailableWithdrawn1
DB01132PioglitazoneNot AvailableCompleted1
DB00635PrednisoneNot AvailableActive Not Recruiting1
DB00635PrednisoneNot AvailableCompleted1
DB00165PyridoxineNot AvailableCompleted1
DB00811RibavirinNot AvailableWithdrawn1
DB00073RituximabNot AvailableTerminated1
DB00073RituximabNot AvailableWithdrawn1
DB00728RocuroniumNot AvailableRecruiting1
DB11365SennosidesNot AvailableCompleted1
DB00658SevelamerNot AvailableCompleted1
DB00658SevelamerNot AvailableWithdrawn1
DB00877SirolimusNot AvailableCompleted1
DB09153Sodium chlorideNot AvailableCompleted1
DB01015SulfamethoxazoleNot AvailableCompleted1
DB00864TacrolimusNot AvailableActive Not Recruiting1
DB00864TacrolimusNot AvailableRecruiting2
DB06273TocilizumabNot AvailableTerminated1
DB00440TrimethoprimNot AvailableCompleted1
DB00512VancomycinNot AvailableCompleted1
DB11094Vitamin DNot AvailableCompleted3