Infection NOS

Also known as: INFECTION / Infections

DrugDrug NameDrug Description
DB03166Acetic acidAcetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.
DB00415AmpicillinAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
DB00626BacitracinBacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically. Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis.
DB04209DequaliniumDequalinium is a quaternary ammonium cation that contains two quaternary quinolinium units linked by an N-decylene chain. It is an antiseptic and disinfectant agent with a broad bactericidal and fungicidal activity. It is most commonly available as a dichloride salt but is available as other various salts as well. It is used in wound dressings and mouth infections and may also have antifungal action, but may associate with skin ulceration. Dequalinium chloride is used as an active ingredient in tablets as Fluomizin for vaginal bacterial infections and in topical bacteriostat formulation as Dequadin. It has been studied for use in treatment of malaria and acute promyelocytic leukemia. Its multiple mode of action is thought to reduce the risk of resistance of pathogens.
DB00663FlumethasoneFlumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
DB00452FramycetinA component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)
DB00406Gentian violet cationA dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
DB02325Isopropyl AlcoholAn isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic. [PubChem]
DB03651Picric acidUsed as antiseptic, astringent, and stimulant for epitheliazation.
DB01032ProbenecidThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. [PubChem]
DB13969Quaternium-24Not Available
DrugDrug NameTargetType
DB03166Acetic acidSolute carrier organic anion transporter family member 2B1transporter
DB03166Acetic acidMonocarboxylate transporter 1transporter
DB00415AmpicillinSerum albumincarrier
DB00415AmpicillinSolute carrier family 22 member 5transporter
DB00415AmpicillinSolute carrier family 15 member 1transporter
DB00415AmpicillinSolute carrier family 15 member 2transporter
DB00415AmpicillinPenicillin-binding protein 2atarget
DB00415AmpicillinPenicillin-binding protein 1btarget
DB00415AmpicillinPenicillin-binding protein 3target
DB00415AmpicillinPenicillin-binding protein 1Atarget
DB00415AmpicillinPenicillin-binding protein 2Btarget
DB00415AmpicillinMonocarboxylate transporter 1transporter
DB00415AmpicillinSolute carrier family 15 member 1target
DB00415AmpicillinSolute carrier family 15 member 2target
DB00415AmpicillinAngiopoietin-1 receptortarget
DB00626BacitracinAlpha-2-macroglobulintarget
DB00626BacitracinInsulin-degrading enzymetarget
DB00626BacitracinC55-isoprenyl pyrophosphatetarget
DB04209DequaliniumHTH-type transcriptional regulator QacRtarget
DB04209DequaliniumAcriflavine resistance protein Btarget
DB04209DequaliniumE3 ubiquitin-protein ligase XIAPtarget
DB04209DequaliniumcGMP-gated cation channel alpha-1target
DB04209DequaliniumCalcium-activated potassium channel subunit alpha-1target
DB00663FlumethasoneCorticosteroid-binding globulincarrier
DB00663FlumethasoneGlucocorticoid receptortarget
DB00663FlumethasoneCytochrome P450 3A4enzyme
DB00452Framycetin30S ribosomal protein S12target
DB00452Framycetin16S rRNAtarget
DB00452FramycetinC-X-C chemokine receptor type 4target
DB00406Gentian violet cationDNAtarget
DB00406Gentian violet cationSolute carrier family 22 member 1transporter
DB02325Isopropyl AlcoholGTP cyclohydrolase 1target
DB02325Isopropyl AlcoholSubtilisin BPN'target
DB02325Isopropyl AlcoholRibonuclease pancreatictarget
DB02325Isopropyl AlcoholTrypsin-2target
DB02325Isopropyl AlcoholAldehyde oxidoreductasetarget
DB02325Isopropyl AlcoholGanglioside GM2 activatortarget
DB02325Isopropyl AlcoholThermolysintarget
DB02325Isopropyl AlcoholChitotriosidase-1target
DB02325Isopropyl AlcoholAdenosylhomocysteinasetarget
DB02325Isopropyl AlcoholSpliceosome RNA helicase DDX39Btarget
DB02325Isopropyl AlcoholDNA mismatch repair protein MutLtarget
DB02325Isopropyl AlcoholGag-Pro-Pol polyproteintarget
DB02325Isopropyl AlcoholLysozymetarget
DB02325Isopropyl AlcoholGlucarate dehydratasetarget
DB02325Isopropyl AlcoholmRNA-capping enzymetarget
DB02325Isopropyl AlcoholFMN-dependent NADH-azoreductasetarget
DB02325Isopropyl AlcoholTranscription termination/antitermination protein NusGtarget
DB02325Isopropyl Alcohol1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenasetarget
DB02325Isopropyl AlcoholGrowth/differentiation factor 5target
DB02325Isopropyl AlcoholIg kappa chain V-IV region Lentarget
DB02325Isopropyl AlcoholPectate lyasetarget
DB02325Isopropyl AlcoholGag polyproteintarget
DB02325Isopropyl AlcoholPhospholipase A2, membrane associatedtarget
DB02325Isopropyl AlcoholScaffolding dockerin binding protein Atarget
DB02325Isopropyl AlcoholAlr1529 proteintarget
DB02325Isopropyl AlcoholL-xylulose reductasetarget
DB02325Isopropyl AlcoholPeroxiredoxin-6target
DB02325Isopropyl AlcoholHydrolase, TatD familytarget
DB02325Isopropyl AlcoholTumor necrosis factortarget
DB02325Isopropyl AlcoholTartrate-resistant acid phosphatase type 5target
DB03651Picric acidPentaerythritol tetranitrate reductasetarget
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidCytochrome P450 2C19enzyme
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DrugDrug NamePhaseStatusCount
DB00787Acyclovir1Completed1
DB00681Amphotericin B1Completed1
DB00415Ampicillin1Completed1
DB00362Anidulafungin1Completed1
DB00207Azithromycin1Completed1
DB00520Caspofungin1Completed1
DB01327Cefazolin1Completed1
DB06590Ceftaroline fosamil1Completed1
DB00878Chlorhexidine1Active Not Recruiting1
DB00537Ciprofloxacin1Completed1
DB00741Hydrocortisone1Completed1
DB00916Metronidazole1Completed2
DB11431Moxidectin1Completed2
DB00218Moxifloxacin1Completed1
DB00319Piperacillin1Completed1
DB00319Piperacillin1Recruiting1
DB01045Rifampicin1Terminated1
DB09153Sodium Chloride1Completed2
DB01606Tazobactam1Completed1
DB01606Tazobactam1Recruiting1
DB00577Valaciclovir1Unknown Status1
DB05237rhMBL1Withdrawn1
DB06151Acetylcysteine1 / 2Completed1
DB00362Anidulafungin1 / 2Completed1
DB00262Carmustine1 / 2Completed1
DB00531Cyclophosphamide1 / 2Completed1
DB00974Edetic Acid1 / 2Withdrawn1
DB00898Ethanol1 / 2Withdrawn1
DB06689Ethanolamine oleate1 / 2Withdrawn1
DB00099Filgrastim1 / 2Completed1
DB01042Melphalan1 / 2Completed1
DB06440Ravuconazole1 / 2Completed1
DB01015Sulfamethoxazole1 / 2Withdrawn1
DB00684Tobramycin1 / 2Completed1
DB00440Trimethoprim1 / 2Withdrawn1
DB00321Amitriptyline2Completed1
DB00362Anidulafungin2Unknown Status1
DB06692Aprotinin2Recruiting1
DB12430BC-37812Completed1
DB00520Caspofungin2Terminated1
DB11121Chloroxylenol2Recruiting1
DB01211Clarithromycin2Recruiting1
DB00766Clavulanate2Completed2
DB00531Cyclophosphamide2Completed1
DB00080Daptomycin2Completed1
DB04933Eritoran2Completed1
DB00898Ethanol2Completed1
DB00773Etoposide2Completed1
DB09222Fibrinogen Human2Recruiting1
DB00099Filgrastim2Completed1
DB09560Filgrastim2Completed1
DB01073Fludarabine2Completed1
DB11571Human Thrombin2Recruiting1
DB10300Human papillomavirus type 11 L1 capsid protein antigen2Completed1
DB00028Immune Globulin Human2Completed1
DB01042Melphalan2Completed1
DB00563Methotrexate2Completed1
DB00994Neomycin2Recruiting1
DB00877Sirolimus2Completed1
DB01015Sulfamethoxazole2Recruiting1
DB00864Tacrolimus2Completed1
DB06402Telavancin2Completed1
DB01607Ticarcillin2Completed2
DB08604Triclosan2Completed1
DB00440Trimethoprim2Recruiting1
DB00512Vancomycin2Completed1
DB00512Vancomycin2Enrolling by Invitation1
DB00582Voriconazole2Completed1
DB00582Voriconazole2Terminated1
DB01060Amoxicillin2 / 3Completed1
DB06590Ceftaroline fosamil2 / 3Completed1
DB01212Ceftriaxone2 / 3Completed1
DB00766Clavulanate2 / 3Completed1
DB00841Dobutamine2 / 3Completed1
DB00196Fluconazole2 / 3Completed1
DB00368Norepinephrine2 / 3Completed1
DB06151Acetylcysteine3Recruiting1
DB01060Amoxicillin3Completed1
DB01060Amoxicillin3Terminated1
DB00681Amphotericin B3Completed1
DB00074Basiliximab3Completed1
DB01327Cefazolin3Completed1
DB01327Cefazolin3Recruiting1
DB01413Cefepime3Unknown Status1
DB01212Ceftriaxone3Completed1
DB00878Chlorhexidine3Completed1
DB00169Cholecalciferol3Completed1
DB00537Ciprofloxacin3Completed1
DB00766Clavulanate3Terminated1
DB01190Clindamycin3Withdrawn1
DB01147Cloxacillin3Completed1
DB00803Colistin3Unknown Status1
DB00080Daptomycin3Completed1
DB01234Dexamethasone3Completed1
DB06211Doripenem3Terminated1
DB00879Emtricitabine3Unknown Status1
DB00303Ertapenem3Completed2
DB00099Filgrastim3Completed1
DB00301Flucloxacillin3Completed1
DB00196Fluconazole3Completed1
DB01004Ganciclovir3Completed1
DB00798Gentamicin3Completed1
DB01050Ibuprofen3Terminated1
DB01137Levofloxacin3Completed1
DB01137Levofloxacin3Terminated1
DB01137Levofloxacin3Unknown Status1
DB00760Meropenem3Terminated1
DB00916Metronidazole3Completed1
DB00218Moxifloxacin3Completed1
DB00218Moxifloxacin3Terminated1
DB00646Nystatin3Completed1
DB01165Ofloxacin3Completed1
DB06610Omiganan3Completed2
DB00713Oxacillin3Completed1
DB00008Peginterferon alfa-2a3Completed1
DB00319Piperacillin3Completed1
DB01263Posaconazole3Completed1
DB06812Povidone-iodine3Completed1
DB06817Raltegravir3Unknown Status1
DB00811Ribavirin3Completed2
DB00811Ribavirin3Terminated1
DB00020Sargramostim3Completed1
DB06290Simeprevir3Completed1
DB09153Sodium Chloride3Active Not Recruiting1
DB01015Sulfamethoxazole3Completed1
DB12473Taurolidine3Completed1
DB01606Tazobactam3Completed1
DB05521Telaprevir3Terminated1
DB00976Telithromycin3Completed1
DB00300Tenofovir disoproxil3Unknown Status1
DB00560Tigecycline3Withdrawn1
DB00440Trimethoprim3Completed1
DB01610Valganciclovir3Completed1
DB00512Vancomycin3Completed1
DB00512Vancomycin3Recruiting1
DB00582Voriconazole3Completed2
DB00479Amikacin4Active Not Recruiting1
DB01060Amoxicillin4Completed2
DB00355Aztreonam4Active Not Recruiting2
DB12768BCG vaccine4Recruiting1
DB01327Cefazolin4Withdrawn1
DB06590Ceftaroline fosamil4Completed3
DB00438Ceftazidime4Unknown Status1
DB01212Ceftriaxone4Active Not Recruiting1
DB01112Cefuroxime4Active Not Recruiting1
DB01112Cefuroxime4Completed1
DB00878Chlorhexidine4Recruiting1
DB11121Chloroxylenol4Completed1
DB00537Ciprofloxacin4Active Not Recruiting1
DB00537Ciprofloxacin4Withdrawn1
DB00766Clavulanate4Completed2
DB00803Colistin4Unknown Status1
DB00531Cyclophosphamide4Recruiting1
DB06779Dalteparin4Completed1
DB06211Doripenem4Completed1
DB00055Drotrecogin alfa4Completed1
DB14240Echinacea4Completed1
DB00303Ertapenem4Completed1
DB01044Gatifloxacin4Unknown Status1
DB00798Gentamicin4Active Not Recruiting1
DB00798Gentamicin4Unknown Status1
DB01598Imipenem4Active Not Recruiting1
DB02325Isopropyl Alcohol4Recruiting1
DB00218Moxifloxacin4Unknown Status1
DB01165Ofloxacin4Unknown Status1
DB06812Povidone-iodine4Recruiting1
DB06812Povidone-iodine4Unknown Status1
DB09153Sodium Chloride4Recruiting1
DB06149Teicoplanin4Completed1
DB12343Temocillin4Recruiting1
DB00512Vancomycin4Completed2
DB00582Voriconazole4Terminated1
DB06361rsPSMA Vaccine4Completed1
DB00802AlfentanilNot AvailableRecruiting1
DB01238AripiprazoleNot AvailableRecruiting1
DB01076AtorvastatinNot AvailableCompleted1
DB00626BacitracinNot AvailableCompleted1
DB00520CaspofunginNot AvailableCompleted1
DB01327CefazolinNot AvailableEnrolling by Invitation1
DB00438CeftazidimeNot AvailableRecruiting1
DB01212CeftriaxoneNot AvailableNot Yet Recruiting1
DB01112CefuroximeNot AvailableUnknown Status1
DB00878ChlorhexidineNot AvailableCompleted1
DB00878ChlorhexidineNot AvailableWithdrawn1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableCompleted2
DB00537CiprofloxacinNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableTerminated1
DB01211ClarithromycinNot AvailableCompleted2
DB00363ClozapineNot AvailableRecruiting1
DB00080DaptomycinNot AvailableWithdrawn1
DB01234DexamethasoneNot AvailableRecruiting1
DB00829DiazepamNot AvailableRecruiting1
DB01320FosphenytoinNot AvailableRecruiting1
DB00798GentamicinNot AvailableCompleted1
DB00874GuaifenesinNot AvailableCompleted1
DB00502HaloperidolNot AvailableRecruiting1
DB01109HeparinNot AvailableRecruiting1
DB00327HydromorphoneNot AvailableRecruiting1
DB01202LevetiracetamNot AvailableRecruiting1
DB01137LevofloxacinNot AvailableCompleted1
DB01137LevofloxacinNot AvailableNot Yet Recruiting1
DB00601LinezolidNot AvailableRecruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB00760MeropenemNot AvailableNot Yet Recruiting1
DB00760MeropenemNot AvailableRecruiting3
DB00959MethylprednisoloneNot AvailableRecruiting1
DB00683MidazolamNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00295MorphineNot AvailableRecruiting1
DB00218MoxifloxacinNot AvailableTerminated1
DB01024Mycophenolic acidNot AvailableNot Yet Recruiting1
DB00994NeomycinNot AvailableActive Not Recruiting1
DB00994NeomycinNot AvailableCompleted1
DB00994NeomycinNot AvailableRecruiting1
DB00994NeomycinNot AvailableUnknown Status1
DB00622NicardipineNot AvailableRecruiting1
DB00334OlanzapineNot AvailableRecruiting1
DB11133Omega-3 fatty acidsNot AvailableActive Not Recruiting1
DB00198OseltamivirNot AvailableRecruiting1
DB00008Peginterferon alfa-2aNot AvailableCompleted1
DB00312PentobarbitalNot AvailableRecruiting1
DB00319PiperacillinNot AvailableRecruiting1
DB00781Polymyxin B SulfateNot AvailableCompleted1
DB06812Povidone-iodineNot AvailableWithdrawn1
DB09345PramocaineNot AvailableCompleted1
DB00818PropofolNot AvailableRecruiting1
DB01224QuetiapineNot AvailableRecruiting1
DB00863RanitidineNot AvailableNot Yet Recruiting1
DB00811RibavirinNot AvailableCompleted1
DB00734RisperidoneNot AvailableRecruiting1
DB00864TacrolimusNot AvailableNot Yet Recruiting1
DB01606TazobactamNot AvailableRecruiting1
DB06149TeicoplaninNot AvailableUnknown Status1
DB12343TemocillinNot AvailableNot Yet Recruiting2
DB00560TigecyclineNot AvailableCompleted1
DB00373TimololNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00273TopiramateNot AvailableRecruiting1
DB00313Valproic AcidNot AvailableRecruiting1
DB00512VancomycinNot AvailableCompleted1
DB00512VancomycinNot AvailableEnrolling by Invitation1
DB00512VancomycinNot AvailableRecruiting2
DB00512VancomycinNot AvailableTerminated2
DB00512VancomycinNot AvailableUnknown Status2
DB00512VancomycinNot AvailableWithdrawn1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1