Chronic Obstructive Pulmonary Disease (COPD)

Also known as: Chronic Obstructive Lung Disease (COLD) / Chronic Obstructive Pulmonary Disease, COPD / COPD / Chronic Obstructive Airway Disease / Chronic Obstructive Pulmonary Disease / CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) / Chronic Obstructive Lung Disease / Chronic Obstructive Lung Diseases / COPD, Chronic Obstructive Pulmonary Disease / Chronic Obstructive Bronchopneumopathy / Chronic Obstructive Pulmonary Disease(COPD) / Chronic Obstructive Pulmonary Diseases / COAD / Chronic obstructive pulmonary disease finding / Hyperactive airway disease / Chronic airflow limitation / Chronic obstructive airway disease NOS / Obstructive airways disease (chronic) / Chronic obstructive airways disease / Pulmonary Disease, Chronic Obstructive / Chronic obstruct airways disease

DrugDrug NameDrug Description
DB08897AclidiniumAclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
DB01274ArformoterolArformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. Arformoterol inhalation is used to prevent bronchoconstriction in people with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients using long acting beta agonists for the treatment of asthma.
DB01222BudesonideBudesonide is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, and allergic rhinitis. [PubChem] The extended release oral tablet, marketed as Uceris, was FDA approved on January 14, 2013 for the management of ulcerative colitis. Budesonide is provided as a mixture of two epimers (22R and 22S). Interestingly, the 22R form is two times more active than the 22S epimer. The two forms do not interconvert.
DB00561DoxapramA central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
DB08906Fluticasone furoateFluticasone furoate is a synthetic trifluorinated corticosteroid with potent anti-inflammatory activity. Despite the similarity in the names, fluticasone furoate and fluticasone propionate are different drugs with different properties. It is marketed under the brand name, Veramyst in the US by GlaxoSmithKline for the management of chronic obstructive pulmonary disease (COPD). FDA approved on April 27, 2007. Fluticasone furoate is available as a combination product with vilanterol, a long-acting beta-2 agonist, under the tradename Breo Ellipta. Approved by the FDA in 2013, its use is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.
DB00588Fluticasone propionateFluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonase®. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymista™. Dymista™ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.
DB00983FormoterolFormoterol is a long-acting (12 hours) beta2-agonist used in the management of asthma and/or chronic obstructive pulmonary disease (COPD). Inhaled formoterol works like other beta2-agonists, causing bronchodilatation through relaxation of the smooth muscle in the airway so as to treat the exacerbation of asthma.
DB00986GlycopyrroniumGlycopyrronium (as the bromide salt glycopyrrolate) is a synthetic anticholinergic agent with a quaternary ammonium structure. A muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics. In October 2015, glycopyrrolate was approved by the FDA for use as a standalone treatment for Chronic obstructive pulmonary disease (COPD), as Seebri Neohaler.
DB05039IndacaterolIndacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) under the trade name Onbrez on November 30, 2009, and by the United States Food and Drug Administration (FDA), under the trade name Arcapta Neohaler, on July 1, 2011. Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
DB00332Ipratropium bromideA muscarinic antagonist structurally related to atropine but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
DB09080OlodaterolOlodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. Beta2-adrenergic receptors are membrane-bound receptors that are normally activated by endogenous epinephrine whose signalling, via a downstream L-type calcium channel interaction, mediates smooth muscle relaxation and bronchodilation. Activation of the receptor stimulates an associated G protein which then activates adenylate cyclase, catalyzing the formation of cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA). Elevation of these two molecules induces bronchodilation by relaxation of airway smooth muscles. It is by this mechanism that olodaterol is used for the treatment of chronic obstructive pulmonary disease (COPD) and the progressive airflow obstruction that is characteristic of it. Treatment with bronchodilators helps to mitigate associated symptoms such as shortness of breath, cough, and sputum production. Single doses of olodaterol have been shown to improve forced expiratory volume in 1 sec (FEV1) for 24 h in patients with COPD, allowing once daily dosing. A once-a-day treatment with a LABA has several advantages over short-acting bronchodilators and twice-daily LABAs including improved convenience and compliance and improved airflow over a 24-hour period. Despite similarities in symptoms, olodaterol is not indicated for the treatment of acute exacerbations of COPD or for the treatment of asthma.
DB01303OxtriphyllineOxtriphylline is the choline salt form of theophylline. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Its main physiological reponse is to dilate the bronchioles. As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications as the other theophyllines). It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available.
DB01656RoflumilastRoflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.
DB00938SalmeterolSalmeterol is a long-acting beta2-adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.
DB01409TiotropiumTiotropium is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
DB09076UmeclidiniumUmeclidinium is a long-acting muscarinic antagonist (LAMA) used as maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). It is available as a once-daily inhalation monotherapy or as a fixed-dose combination product with the long-acting beta2-agonist vilanterol. COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than 80%. By blocking the M3 muscarinic receptor which is highly expressed in airway smooth muscle of the lungs, umeclidinium inhibits the binding of acetylcholine and thereby opens up the airways by preventing bronchoconstriction. Its use has been shown to provide clinically significant, sustained improvements in lung function.
DB09082VilanterolVilanterol is a selective long-acting beta2-adrenergic agonist (LABA) with inherent 24-hour activity for once daily treatment of COPD and asthma. Its pharmacological effect is attributable to stimulation of intracellular adenylyl cyclase which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increases in cyclic AMP are associated with relaxation of bronchial smooth muscle and inhibition of release of hypersensitivity mediators from mast cells in the lungs. Vilanterol is approved for use in several combination products such as with fluticasone furoate under the tradename Breo Ellipta and in combination with umeclidinium bromide as Anoro Ellipta. Approved by the FDA in 2013, use of Breo Ellipta is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.
DrugDrug NameTargetType
DB08897AclidiniumMuscarinic acetylcholine receptor M1target
DB08897AclidiniumMuscarinic acetylcholine receptor M2target
DB08897AclidiniumMuscarinic acetylcholine receptor M3target
DB08897AclidiniumMuscarinic acetylcholine receptor M4target
DB08897AclidiniumMuscarinic acetylcholine receptor M5target
DB08897AclidiniumCholinesteraseenzyme
DB01274ArformoterolBeta-2 adrenergic receptortarget
DB01274ArformoterolCytochrome P450 2D6enzyme
DB01274ArformoterolCytochrome P450 2C19enzyme
DB01274ArformoterolCytochrome P450 2A6enzyme
DB01274ArformoterolCytochrome P450 2C9enzyme
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB00561DoxapramPotassium channel subfamily K member 3target
DB00561DoxapramPotassium channel subfamily K member 9target
DB08906Fluticasone furoateCytochrome P450 3A4enzyme
DB08906Fluticasone furoateGlucocorticoid receptortarget
DB08906Fluticasone furoateMultidrug resistance protein 1transporter
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00983FormoterolBeta-2 adrenergic receptortarget
DB00983FormoterolCytochrome P450 2C19enzyme
DB00983FormoterolCytochrome P450 2C9enzyme
DB00983FormoterolCytochrome P450 2D6enzyme
DB00983FormoterolCytochrome P450 2A6enzyme
DB00983FormoterolBeta-1 adrenergic receptortarget
DB00983FormoterolBeta-3 adrenergic receptortarget
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M1target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M3target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M2target
DB05039IndacaterolBeta-2 adrenergic receptortarget
DB05039IndacaterolCytochrome P450 3A4enzyme
DB05039IndacaterolUDP-glucuronosyltransferase 1-1enzyme
DB05039IndacaterolMultidrug resistance protein 1transporter
DB00332Ipratropium bromideMuscarinic acetylcholine receptor M1target
DB00332Ipratropium bromideMuscarinic acetylcholine receptor M2target
DB00332Ipratropium bromideCytochrome P450 2D6enzyme
DB00332Ipratropium bromideCytochrome P450 3A4enzyme
DB00332Ipratropium bromideMuscarinic acetylcholine receptor M3target
DB00332Ipratropium bromideSolute carrier family 22 member 5transporter
DB00332Ipratropium bromideSolute carrier family 22 member 4transporter
DB09080OlodaterolBeta-2 adrenergic receptortarget
DB09080OlodaterolCytochrome P450 2C9enzyme
DB09080OlodaterolCytochrome P450 2C8enzyme
DB01303OxtriphyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01303OxtriphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01303OxtriphyllineAdenosine receptor A2atarget
DB01303OxtriphyllineAdenosine receptor A1target
DB01303OxtriphyllineCytochrome P450 1A2enzyme
DB01303OxtriphyllineSolute carrier family 22 member 7transporter
DB01303OxtriphyllineHistone deacetylase 2target
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB00938SalmeterolBeta-2 adrenergic receptortarget
DB00938SalmeterolCytochrome P450 3A4enzyme
DB00938SalmeterolCytochrome P450 2C8enzyme
DB00938SalmeterolCytochrome P450 3A5enzyme
DB00938SalmeterolCytochrome P450 3A7enzyme
DB00938SalmeterolBeta-1 adrenergic receptortarget
DB00938SalmeterolBeta-3 adrenergic receptortarget
DB01409TiotropiumMuscarinic acetylcholine receptor M3target
DB01409TiotropiumCytochrome P450 2D6enzyme
DB01409TiotropiumCytochrome P450 3A4enzyme
DB01409TiotropiumMuscarinic acetylcholine receptor M1target
DB01409TiotropiumMuscarinic acetylcholine receptor M2target
DB01409TiotropiumSolute carrier family 22 member 5transporter
DB01409TiotropiumSolute carrier family 22 member 4transporter
DB01409TiotropiumMuscarinic acetylcholine receptor M4target
DB01409TiotropiumMuscarinic acetylcholine receptor M5target
DB09076UmeclidiniumMuscarinic acetylcholine receptor M1target
DB09076UmeclidiniumMuscarinic acetylcholine receptor M2target
DB09076UmeclidiniumMuscarinic acetylcholine receptor M3target
DB09076UmeclidiniumMuscarinic acetylcholine receptor M4target
DB09076UmeclidiniumMuscarinic acetylcholine receptor M5target
DB09076UmeclidiniumCytochrome P450 2D6enzyme
DB09076UmeclidiniumMultidrug resistance protein 1transporter
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DrugDrug NamePhaseStatusCount
DB00260Cycloserine0Recruiting1
DB04335Inosine0Terminated1
DB08820Ivacaftor0Completed1
DB00556Perflutren0Not Yet Recruiting1
DB11104Sulfur hexafluoride0Not Yet Recruiting1
DB01409Tiotropium0Completed1
DB12100Abediterol1Completed1
DB11863Alvelestat1Completed2
DB12618Apocynin1Completed1
DB12054BQ-1231Recruiting1
DB00394Beclomethasone dipropionate1Completed2
DB12023Benralizumab1Completed1
DB01222Budesonide1Completed3
DB12800CHF-60011Completed2
DB00091Cyclosporine1Completed1
DB12135Elubrixin1Completed2
DB00950Fexofenadine1Recruiting1
DB00588Fluticasone propionate1Completed4
DB00983Formoterol1Completed4
DB12296GS-57451Completed1
DB00986Glycopyrronium1Completed6
DB06583Glycopyrronium1Completed1
DB00986Glycopyrronium1Not Yet Recruiting1
DB05039Indacaterol1Completed2
DB04335Inosine1Active Not Recruiting1
DB01137Levofloxacin1Completed1
DB12270Losmapimod1Completed1
DB05063Mitoquinone1Recruiting1
DB00218Moxifloxacin1Completed3
DB11711Navarixin1Terminated1
DB09140Oxygen1Completed1
DB12408PF-036356591Completed1
DB11722PH-7978041Completed1
DB05392Perflubutane1Completed1
DB00692Phentolamine1Recruiting1
DB06809Plerixafor1Recruiting1
DB00860Prednisolone1Completed2
DB01366Procaterol1Completed1
DB04216Quercetin1Completed1
DB00863Ranitidine1Recruiting1
DB11855Revefenacin1Completed2
DB01656Roflumilast1Completed1
DB00938Salmeterol1Completed5
DB00360Sapropterin1Recruiting1
DB00641Simvastatin1Completed1
DB00641Simvastatin1Unknown Status1
DB01409Tiotropium1Completed4
DB00374Treprostinil1Completed1
DB09076Umeclidinium1Completed1
DB06577Vilanterol1Completed1
DB09082Vilanterol1Completed1
DB00126Vitamin C1Recruiting1
DB09315Xenon-1331Recruiting1
DB01632Alpha-Phosphoribosylpyrophosphoric Acid1 / 2Recruiting1
DB06168Canakinumab1 / 2Completed1
DB00091Cyclosporine1 / 2Completed1
DB00983Formoterol1 / 2Completed1
DB00986Glycopyrronium1 / 2Completed1
DB05039Indacaterol1 / 2Completed1
DB00742Mannitol1 / 2Withdrawn1
DB09140Oxygen1 / 2Withdrawn1
DB01409Tiotropium1 / 2Completed3
DB05195ADC40222Completed1
DB13012AQX-11252Unknown Status1
DB11961AZD-12362Completed2
DB11946AZD-19812Completed1
DB12002AZD-48182Completed1
DB12280AZD-54232Completed1
DB12115AZD-91642Completed1
DB12100Abediterol2Completed1
DB00945Acetylsalicylic acid2Completed1
DB00945Acetylsalicylic acid2Recruiting1
DB00945Acetylsalicylic acid2Unknown Status1
DB08897Aclidinium2Completed5
DB11863Alvelestat2Completed4
DB01274Arformoterol2Completed1
DB01076Atorvastatin2Completed1
DB00207Azithromycin2Terminated2
DB08879Belimumab2Not Yet Recruiting1
DB12023Benralizumab2Completed1
DB00612Bisoprolol2Terminated1
DB00559Bosentan2Unknown Status1
DB01222Budesonide2Completed4
DB01222Budesonide2Not Yet Recruiting1
DB01222Budesonide2Recruiting1
DB12800CHF-60012Completed1
DB12800CHF-60012Not Yet Recruiting1
DB00878Chlorhexidine2Recruiting1
DB00758Clopidogrel2Completed1
DB12140Dilmapimod2Completed1
DB12192Emeramide2Not Yet Recruiting1
DB00824Enprofylline2Recruiting1
DB05057Erdosteine2Completed1
DB08917Ferric Carboxymaltose2Recruiting1
DB08906Fluticasone furoate2Recruiting1
DB00588Fluticasone propionate2Completed4
DB00588Fluticasone propionate2Recruiting1
DB00588Fluticasone propionate2Terminated1
DB00588Fluticasone propionate2Withdrawn1
DB00983Formoterol2Completed21
DB00983Formoterol2Recruiting1
DB00983Formoterol2Withdrawn1
DB00986Glycopyrronium2Completed7
DB06583Glycopyrronium2Completed4
DB08818Hyaluronic acid2Unknown Status1
DB01088Iloprost2Completed1
DB01088Iloprost2Terminated1
DB00028Immune Globulin Human2Not Yet Recruiting1
DB00028Immune Globulin Human2Recruiting1
DB05039Indacaterol2Completed9
DB00065Infliximab2Completed1
DB00332Ipratropium bromide2Completed4
DB08820Ivacaftor2Recruiting1
DB11914Lebrikizumab2Completed1
DB01137Levofloxacin2Completed1
DB01137Levofloxacin2Recruiting1
DB12270Losmapimod2Completed3
DB00227Lovastatin2Completed1
DB00351Megestrol acetate2Completed1
DB11711Navarixin2Terminated2
DB12408PF-036356592Completed1
DB11722PH-7978042Completed1
DB01708Prasterone2Unknown Status1
DB00980Ramelteon2Completed1
DB11855Revefenacin2Completed4
DB01656Roflumilast2Completed1
DB01656Roflumilast2Recruiting1
DB01656Roflumilast2Terminated1
DB01098Rosuvastatin2Completed1
DB01001Salbutamol2Completed1
DB00938Salmeterol2Completed6
DB00938Salmeterol2Withdrawn1
DB00360Sapropterin2Recruiting1
DB09153Sodium Chloride2Recruiting2
DB09153Sodium Chloride2Terminated1
DB00820Tadalafil2Completed1
DB08869Tesamorelin2Terminated1
DB05298Tetomilast2Completed1
DB12166Tetomilast2Completed1
DB12166Tetomilast2Terminated1
DB08816Ticagrelor2Completed1
DB01409Tiotropium2Completed8
DB01409Tiotropium2Terminated1
DB01409Tiotropium2Withdrawn1
DB00374Treprostinil2Not Yet Recruiting1
DB00374Treprostinil2Recruiting1
DB00755Tretinoin2Completed1
DB09076Umeclidinium2Recruiting1
DB09082Vilanterol2Recruiting1
DB00199Erythromycin2 / 3Unknown Status1
DB00983Formoterol2 / 3Completed1
DB00327Hydromorphone2 / 3Completed1
DB05039Indacaterol2 / 3Completed2
DB00295Morphine2 / 3Completed1
DB01656Roflumilast2 / 3Completed1
DB00277Theophylline2 / 3Completed1
DB01409Tiotropium2 / 3Completed1
DB08897Aclidinium3Completed14
DB08897Aclidinium3Recruiting1
DB01274Arformoterol3Completed5
DB00207Azithromycin3Completed1
DB00207Azithromycin3Recruiting3
DB00207Azithromycin3Unknown Status1
DB00074Basiliximab3Completed1
DB00394Beclomethasone dipropionate3Completed1
DB01222Budesonide3Active Not Recruiting1
DB01222Budesonide3Completed5
DB01222Budesonide3Recruiting1
DB00537Ciprofloxacin3Completed1
DB00537Ciprofloxacin3Recruiting1
DB00012Darbepoetin alfa3Withdrawn1
DB00254Doxycycline3Completed1
DB00254Doxycycline3Unknown Status1
DB05057Erdosteine3Unknown Status1
DB01175Escitalopram3Withdrawn1
DB00588Fluticasone propionate3Completed5
DB00588Fluticasone propionate3Withdrawn3
DB00983Formoterol3Active Not Recruiting1
DB00983Formoterol3Completed22
DB00983Formoterol3Recruiting2
DB00986Glycopyrronium3Completed15
DB06583Glycopyrronium3Completed14
DB00986Glycopyrronium3Recruiting1
DB06583Glycopyrronium3Withdrawn1
DB09155Helium3Terminated1
DB05039Indacaterol3Completed32
DB00065Infliximab3Completed1
DB01306Insulin Aspart3Terminated1
DB00030Insulin Human3Terminated1
DB00332Ipratropium bromide3Completed2
DB00125L-Arginine3Withdrawn1
DB13139Levosalbutamol3Completed1
DB09337Medical air3Terminated1
DB06612Mepolizumab3Completed1
DB00764Mometasone3Completed2
DB00471Montelukast3Completed1
DB00295Morphine3Recruiting2
DB00295Morphine3Withdrawn1
DB00218Moxifloxacin3Completed1
DB00218Moxifloxacin3Unknown Status1
DB09152Nitrogen3Terminated1
DB09140Oxygen3Terminated1
DB01708Prasterone3Unknown Status1
DB00860Prednisolone3Completed1
DB11855Revefenacin3Completed3
DB01656Roflumilast3Active Not Recruiting1
DB01656Roflumilast3Completed13
DB01001Salbutamol3Completed8
DB00938Salmeterol3Completed13
DB00938Salmeterol3Withdrawn3
DB00203Sildenafil3Unknown Status1
DB00641Simvastatin3Completed2
DB09153Sodium Chloride3Recruiting1
DB01015Sulfamethoxazole3Completed1
DB00231Temazepam3Completed1
DB00871Terbutaline3Completed1
DB00277Theophylline3Completed1
DB01409Tiotropium3Completed24
DB00620Triamcinolone3Completed1
DB00440Trimethoprim3Completed1
DB03424Ubenimex3Completed1
DB06267Udenafil3Completed1
DB09076Umeclidinium3Completed3
DB09076Umeclidinium3Recruiting1
DB01273Varenicline3Completed1
DB01273Varenicline3Not Yet Recruiting1
DB06577Vilanterol3Completed1
DB09082Vilanterol3Completed3
DB09082Vilanterol3Recruiting1
DB12479Zabofloxacin3Completed1
DB00819Acetazolamide4Recruiting7
DB06151Acetylcysteine4Completed2
DB08897Aclidinium4Active Not Recruiting1
DB08897Aclidinium4Completed2
DB08897Aclidinium4Not Yet Recruiting1
DB08897Aclidinium4Recruiting1
DB08897Aclidinium4Withdrawn1
DB00058Alpha-1-proteinase inhibitor4Recruiting1
DB00381Amlodipine4Completed1
DB00381Amlodipine4Recruiting1
DB01060Amoxicillin4Completed1
DB01274Arformoterol4Completed4
DB01274Arformoterol4Terminated1
DB01274Arformoterol4Unknown Status1
DB01076Atorvastatin4Completed1
DB01408Bambuterol4Completed1
DB00394Beclomethasone dipropionate4Completed2
DB11897Beclomethasone dipropionate4Completed1
DB00394Beclomethasone dipropionate4Unknown Status1
DB11897Beclomethasone dipropionate4Withdrawn1
DB11105Benzalkonium4Unknown Status1
DB00612Bisoprolol4Completed1
DB00612Bisoprolol4Recruiting1
DB01222Budesonide4Completed11
DB01222Budesonide4Not Yet Recruiting1
DB01222Budesonide4Recruiting1
DB01222Budesonide4Terminated2
DB01222Budesonide4Unknown Status1
DB01136Carvedilol4Completed1
DB01136Carvedilol4Withdrawn1
DB00520Caspofungin4Unknown Status1
DB04846Celiprolol4Recruiting1
DB11121Chloroxylenol4Recruiting1
DB00537Ciprofloxacin4Not Yet Recruiting1
DB00766Clavulanate4Completed1
DB01380Cortisone acetate4Recruiting1
DB01234Dexamethasone4Completed2
DB01234Dexamethasone4Recruiting1
DB00633Dexmedetomidine4Completed1
DB00633Dexmedetomidine4Not Yet Recruiting1
DB00841Dobutamine4Terminated1
DB00254Doxycycline4Completed1
DB00254Doxycycline4Unknown Status1
DB05057Erdosteine4Withdrawn1
DB00588Fluticasone propionate4Completed8
DB00588Fluticasone propionate4Recruiting1
DB00588Fluticasone propionate4Terminated1
DB00588Fluticasone propionate4Unknown Status1
DB00983Formoterol4Completed13
DB00983Formoterol4Not Yet Recruiting1
DB00983Formoterol4Recruiting3
DB00983Formoterol4Terminated2
DB00983Formoterol4Unknown Status1
DB00983Formoterol4Withdrawn3
DB00492Fosinopril4Completed1
DB00986Glycopyrronium4Completed5
DB06583Glycopyrronium4Completed2
DB00986Glycopyrronium4Not Yet Recruiting1
DB00986Glycopyrronium4Recruiting2
DB00062Human Serum Albumin4Recruiting1
DB00741Hydrocortisone4Recruiting1
DB05039Indacaterol4Completed14
DB05039Indacaterol4Not Yet Recruiting2
DB05039Indacaterol4Recruiting2
DB05039Indacaterol4Withdrawn2
DB00332Ipratropium bromide4Completed4
DB00332Ipratropium bromide4Unknown Status1
DB01026Ketoconazole4Completed1
DB04465Lactose4Completed2
DB13139Levosalbutamol4Completed2
DB00678Losartan4Unknown Status1
DB00331Metformin4Completed1
DB00959Methylprednisolone4Recruiting1
DB00959Methylprednisolone4Terminated1
DB00264Metoprolol4Unknown Status1
DB00264Metoprolol4Withdrawn1
DB00218Moxifloxacin4Recruiting1
DB09080Olodaterol4Not Yet Recruiting1
DB09080Olodaterol4Recruiting1
DB09140Oxygen4Completed1
DB09140Oxygen4Recruiting2
DB00319Piperacillin4Not Yet Recruiting1
DB00860Prednisolone4Completed1
DB00860Prednisolone4Recruiting1
DB00635Prednisone4Active Not Recruiting1
DB00635Prednisone4Recruiting3
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DB01274ArformoterolNot AvailableCompleted2
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DB00394Beclomethasone dipropionateNot AvailableCompleted1
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DB00612BisoprololNot AvailableCompleted1
DB01222BudesonideNot AvailableCompleted1
DB11672CurcuminNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableCompleted1
DB00254DoxycyclineNot AvailableRecruiting1
DB00153ErgocalciferolNot AvailableRecruiting1
DB00813FentanylNot AvailableCompleted2
DB00588Fluticasone propionateNot AvailableCompleted1
DB00588Fluticasone propionateNot AvailableUnknown Status1
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DB00741HydrocortisoneNot AvailableUnknown Status1
DB01088IloprostNot AvailableCompleted1
DB05039IndacaterolNot AvailableCompleted1
DB01309Insulin GlulisineNot AvailableTerminated1
DB00332Ipratropium bromideNot AvailableCompleted2
DB00332Ipratropium bromideNot AvailableTerminated1
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DB00678LosartanNot AvailableRecruiting1
DB00653Magnesium SulfateNot AvailableCompleted1
DB09337Medical airNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableUnknown Status2
DB01183NaloxoneNot AvailableCompleted2
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DB09140OxygenNot AvailableActive Not Recruiting1
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DB00820TadalafilNot AvailableRecruiting1
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DB11094Vitamin DNot AvailableRecruiting1