Post-Operative Pain

Also known as: Pain, Post-operative / Procedural pain / Postoperative pain / Postoperative pain NOS / Pain, Postoperative

DrugDrug NameDrug Description
DB01563Chloral hydrateA mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia.
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB08439ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
DrugDrug NameTargetType
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB08439ParecoxibLactotransferrintarget
DB08439ParecoxibProstaglandin G/H synthase 2target
DB08439ParecoxibCytochrome P450 3A4enzyme
DB08439ParecoxibCytochrome P450 2C9enzyme
DrugDrug NamePhaseStatusCount
DB00230Pregabalin0Completed1
DB00633Dexmedetomidine1 / 2Completed1
DB00083Botulinum toxin type A2Recruiting1
DB00297Bupivacaine2Recruiting2
DB00633Dexmedetomidine2Completed1
DB00633Dexmedetomidine2Terminated1
DB00829Diazepam2Recruiting1
DB01050Ibuprofen2Completed1
DB01009Ketoprofen2Unknown Status1
DB00814Meloxicam2Completed1
DB01017Minocycline2Completed1
DB00295Morphine2Completed2
DB05354Morphine2Completed1
DB00295Morphine2Recruiting1
DB08439Parecoxib2Completed1
DB09145Water2Completed2
DB00316Acetaminophen3Completed1
DB00083Botulinum toxin type A3Completed1
DB00921Buprenorphine3Terminated1
DB00318Codeine3Completed1
DB01234Dexamethasone3Unknown Status1
DB00996Gabapentin3Completed1
DB01050Ibuprofen3Completed2
DB01221Ketamine3Unknown Status1
DB00465Ketorolac3Recruiting1
DB00814Meloxicam3Completed3
DB00295Morphine3Completed1
DB01192Oxymorphone3Completed1
DB01192Oxymorphone3Suspended1
DB00230Pregabalin3Completed1
DB00296Ropivacaine3Withdrawn1
DB00708Sufentanil3Completed3
DB00316Acetaminophen4Completed2
DB00316Acetaminophen4Not Yet Recruiting1
DB00945Acetylsalicylic acid4Not Yet Recruiting1
DB00297Bupivacaine4Completed4
DB00297Bupivacaine4Enrolling by Invitation1
DB00297Bupivacaine4Recruiting1
DB00575Clonidine4Completed1
DB01234Dexamethasone4Recruiting1
DB00668Epinephrine4Recruiting1
DB01628Etoricoxib4Terminated1
DB00813Fentanyl4Completed1
DB00956Hydrocodone4Not Yet Recruiting1
DB00328Indomethacin4Completed1
DB01221Ketamine4Active Not Recruiting1
DB01043Memantine4Unknown Status1
DB00295Morphine4Completed2
DB00295Morphine4Recruiting1
DB00497Oxycodone4Not Yet Recruiting1
DB08439Parecoxib4Completed1
DB00230Pregabalin4Completed1
DB00296Ropivacaine4Active Not Recruiting1
DB00296Ropivacaine4Completed1
DB00316AcetaminophenNot AvailableCompleted1
DB00316AcetaminophenNot AvailableEnrolling by Invitation1
DB00297BupivacaineNot AvailableCompleted1
DB00297BupivacaineNot AvailableTerminated2
DB00318CodeineNot AvailableRecruiting1
DB00813FentanylNot AvailableCompleted1
DB01050IbuprofenNot AvailableCompleted1
DB01002LevobupivacaineNot AvailableCompleted1
DB01002LevobupivacaineNot AvailableNot Yet Recruiting1
DB00281LidocaineNot AvailableCompleted1
DB00333MethadoneNot AvailableCompleted1
DB00295MorphineNot AvailableCompleted1
DB00497OxycodoneNot AvailableCompleted1
DB00296RopivacaineNot AvailableCompleted2
DB09153Sodium chlorideNot AvailableNot Yet Recruiting1