Showing BioInteractions for Sulindac (DB00605)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Sulindac is a Aldose reductase inhibitor | ||
1 | Aldose reductase inhibitors | Citric acid, Exisulind, Fidarestat, Sorbinil, Tolrestat |
2 | Aldose reductase substrates | Brexanolone, Fenofibrate |
Interacting Group | Interacting Drugs | |
---|---|---|
Sulindac is a Mitogen-activated protein kinase 3 inhibitor | ||
1 | Mitogen-activated protein kinase 3 inhibitors | Purvalanol, Ulixertinib |
2 | Mitogen-activated protein kinase 3 inducers | Arsenic trioxide |
Interacting Group | Interacting Drugs | |
---|---|---|
Sulindac is a Peroxisome proliferator-activated receptor delta negative modulator | ||
1 | Peroxisome proliferator-activated receptor delta agonists | Bezafibrate, Cardarine, Glycerin, Icosapent, Treprostinil |
Interacting Group | Interacting Drugs | |
---|---|---|
Sulindac is a Prostaglandin D2 receptor 2 antagonist | ||
1 | Prostaglandin D2 receptor 2 agonists | Alprostadil, Dinoprost, Dinoprostone, Iloprost |
Interacting Group | Interacting Drugs | |
---|---|---|
Sulindac is a Aldo-keto reductase family 1 member B10 inhibitor | ||
1 | Aldo-keto reductase family 1 member B10 inhibitors | Exisulind, Fidarestat |