Showing BioInteractions for DB00530 (Erlotinib)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 3A4 substrate
1Cytochrome P450 3A4 substratesAbemaciclib, Abiraterone, Acenocoumarol, Acetaminophen, Adinazolam, Albendazole, Alclometasone, Alfentanil, Alfuzosin, Aliskiren, Allylestrenol, Almotriptan, Alogliptin, Alosetron, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Argatroban, Aripiprazole, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Avanafil, Avatrombopag, Axitinib, Azelastine, Azithromycin, Banoxantrone, Baricitinib, Bedaquiline, Benidipine, Benzphetamine, Benzyl alcohol, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromazepam, Bromocriptine, Brompheniramine, Budesonide, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Busulfan, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calcitriol, Canagliflozin, Cannabidiol, Carbamazepine, Carbinoxamine, Cariprazine, Carvedilol, Celecoxib, Celiprolol, Cephalexin, Cerivastatin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Cilostazol, Cinacalcet, Cisapride, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clofibrate, clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepate, Clotiazepam, Clozapine, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cytarabine, Dabrafenib, Daclatasvir, Dantrolene, Dapagliflozin, Dapsone, Darifenacin, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexchlorpheniramine maleate, Dexlansoprazole, Dextromethorphan, Dextropropoxyphene, Diazepam, Diclofenac, Dienogest, Digitoxin, Digoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergotamine, Diltiazem, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Dorzolamide, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Dutasteride, Efavirenz, Elbasvir, Eletriptan, Eliglustat, Elvitegravir, Enalapril, Enasidenib, Enzalutamide, Epinastine, Eplerenone, Ergocalciferol, Ergoloid mesylate, Ergonovine, Ergotamine, Erythromycin, Escitalopram, Esomeprazole, Estazolam, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrogens, esterified, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinyl Estradiol, Ethosuximide, Ethylmorphine, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Everolimus, Exemestane, Famciclovir, Felbamate, Felodipine, Fenofibrate, Fentanyl, Fesoterodine, Finasteride, Fingolimod, Flibanserin, Flunisolide, Flunitrazepam, Fluorometholone, Fluoxetine, Flurazepam, Flutamide, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fosamprenavir, Fosnetupitant, Fostamatinib, Fulvestrant, Galantamine, Gefitinib, Gemfibrozil, Glipizide, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halofantrine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydrocodone, Hydrocortisone, Hydromorphone, Hydroxyprogesterone caproate, Ibrutinib, Icotinib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indapamide, Indinavir, Ipecac, Ipratropium, Irinotecan, Isavuconazole, Isavuconazonium, Isosorbide Dinitrate, Isosorbide Mononitrate, Isradipine, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lansoprazole, Lapatinib, Laquinimod, Lenvatinib, Lercanidipine, Letrozole, Levobupivacaine, Levocetirizine, Levomethadyl Acetate, Levomilnacipran, Levonorgestrel, Levothyroxine, Lidocaine, Lisuride, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorcaserin, Lorpiprazole, Losartan, Lovastatin, Lumefantrine, Lurasidone, Macimorelin, Macitentan, Maraviroc, Mebendazole, Medical Cannabis, Medroxyprogesterone acetate, Mefloquine, Meloxicam, Methadone, Methaqualone, Methoxsalen, Methoxyflurane, Methylprednisolone, Methyltestosterone, Metronidazole, Mexiletine, Mianserin, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Modafinil, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naloxegol, Naloxone, Nateglinide, Nefazodone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nicotine, Nifedipine, Nilotinib, Nilvadipine, Nimodipine, Nisoldipine, Nitrazepam, Nitrendipine, Norethisterone, Norgestrel, Nortriptyline, Odanacatib, Olaparib, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Ospemifene, Oxazepam, Oxybutynin, Oxycodone, Oxymorphone, Paclitaxel, Palbociclib, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Pazopanib, Pentamidine, Perampanel, Pergolide, Perhexiline, Permethrin, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenoxybenzamine, Phenprocoumon, Phenytoin, Pilocarpine, Pimecrolimus, Pimozide, Pinacidil, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Podofilox, Pomalidomide, Ponatinib, Posaconazole, Prasterone, Prasugrel, Pravastatin, Prazepam, Praziquantel, Prednisolone, Prednisone, Primaquine, Prochlorperazine, Progesterone, Proguanil, Promazine, Propafenone, Propiverine, Propofol, Propranolol, Pyrazinamide, Quazepam, Quetiapine, Quinacrine, Quinidine, Quinine, Rabeprazole, Raloxifene, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Retapamulin, Rifabutin, Rifampicin, Rilpivirine, Rimonabant, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Rofecoxib, Rolapitant, Romidepsin, Ropinirole, Ropivacaine, Rosuvastatin, Rotigotine, Roxithromycin, Rucaparib, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Selegiline, Selexipag, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simvastatin, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, Spiramycin, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasosartan, Taurochenodeoxycholic acid, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Teniposide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tezacaftor, Theophylline, Thiotepa, Tiagabine, Ticagrelor, Ticlopidine, Tinidazole, Tiotropium, Tipranavir, Tocofersolan, Tocopherol, Tofacitinib, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Troleandomycin, Udenafil, Ulipristal, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vismodegib, Voriconazole, Vortioxetine, Voxilaprevir, Warfarin, Yohimbine, Zafirlukast, Zalcitabine, Zaleplon, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine
2Cytochrome P450 3A4 inhibitorsAcetaminophen, Acetazolamide, Acetyl sulfisoxazole, Aldesleukin, Alprazolam, Ambroxol, Amiodarone, Amlodipine, Amprenavir, Anastrozole, Antipyrine, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, Atomoxetine, Atorvastatin, Azelastine, Azithromycin, Betamethasone, Bicalutamide, Bifonazole, Boceprevir, Bortezomib, Brentuximab vedotin, Bromocriptine, Buprenorphine, Cabergoline, Caffeine, Capsaicin, Caspofungin, Ceritinib, Cerivastatin, Chloramphenicol, Chlorzoxazone, Cilostazol, Cimetidine, Cimicifuga racemosa, Ciprofloxacin, Cisapride, Clarithromycin, Clemastine, Clindamycin, Clofazimine, Clomifene, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cocaine, Colchicine, Conivaptan, Cortisone acetate, Crizotinib, Curcumin, Cyclophosphamide, Cyclosporine, Dalfopristin, Danazol, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Dexamethasone, Dextropropoxyphene, Diazepam, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Docetaxel, Doxorubicin, Doxycycline, Dronedarone, Econazole, Efavirenz, Efonidipine, Elbasvir, Enasidenib, Epinephrine, Ergonovine, Ergotamine, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fentanyl, Fluconazole, Fluoxetine, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Gemfibrozil, Glyburide, Glycerol Phenylbutyrate, Haloperidol, Histamine, Hydralazine, Hydrocortisone, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Indinavir, Indisulam, Irbesartan, Irinotecan, Isavuconazole, Isavuconazonium, Isoniazid, Itraconazole, Ivacaftor, Josamycin, Ketazolam, Ketoconazole, Lansoprazole, Lapatinib, Lercanidipine, Levofloxacin, Levosalbutamol, Lidocaine, Linagliptin, Lomitapide, Lomustine, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Lurasidone, Manidipine, Mefloquine, Mequitazine, Methadone, Methazolamide, Methimazole, Methylergometrine, Methylprednisolone, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirtazapine, Mitoxantrone, Modafinil, Nabilone, Nefazodone, Nelfinavir, Netupitant, Nevirapine, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nisoldipine, Nitrendipine, Nitric Oxide, Norfloxacin, Noscapine, Olanzapine, Olaparib, Omeprazole, Oxetacaine, Oxybutynin, Oxymetholone, Paclitaxel, Palbociclib, Paramethasone, Pazopanib, Peppermint oil, Pergolide, Phenelzine, Pilocarpine, Pimozide, Piperaquine, Posaconazole, Pravastatin, Prednisolone, Prednisone, Primaquine, Progesterone, Propofol, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Repaglinide, Resveratrol, Rilpivirine, Risperidone, Ritonavir, Rivastigmine, Rolitetracycline, Rosuvastatin, Roxithromycin, Rucaparib, Rutin, Salbutamol, Saquinavir, Sarilumab, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sitaxentan, Sorafenib, Stiripentol, Sulfamethoxazole, Sulfanilamide, Sulfinpyrazone, Sulfisoxazole, Tacrolimus, Tadalafil, Tamoxifen, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Thiopental, Ticagrelor, Ticlopidine, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Tramadol, Tranylcypromine, Troglitazone, Troleandomycin, Valproic Acid, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voriconazole, Zafirlukast, Ziprasidone, Zucapsaicin
3Cytochrome P450 3A4 inducersAcetaminophen, Alclometasone, Alimemazine, Aminoglutethimide, Apalutamide, Armodafinil, Artemether, Atorvastatin, Azatadine, Bexarotene, Bosentan, Calcitriol, Carbamazepine, Cefradine, Cerivastatin, Chlorphenesin, Clarithromycin, Clevidipine, Clobazam, Clofibrate, Clotrimazole, Clozapine, Colchicine, Cyclophosphamide, Dabrafenib, Deferasirox, Delafloxacin, Desvenlafaxine, Dexamethasone, Dicloxacillin, Drospirenone, Efavirenz, Eletriptan, Enasidenib, Enzalutamide, Eslicarbazepine acetate, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Exemestane, Felbamate, Flucloxacillin, Fluorometholone, Fluvastatin, Fosaprepitant, Fosphenytoin, Gemfibrozil, Griseofulvin, Guanethidine, Hydrocortamate, Hydrocortisone, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Lansoprazole, Loratadine, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Metamizole, Methadone, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Pantoprazole, Pegvisomant, Pentobarbital, Perampanel, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Prednisone, Primidone, Probenecid, Progesterone, Pyridostigmine, Quinidine, Quinine, Rifabutin, Rifampicin, Rifapentine, Rifaximin, Rilpivirine, Ritonavir, Rofecoxib, Rufinamide, Seratrodast, Simvastatin, St. John's Wort, Sulfinpyrazone, Tamoxifen, Temozolomide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Topiramate, Topotecan, Trametinib, Troglitazone, Vemurafenib
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 3A5 substrate
1Cytochrome P450 3A5 substratesAlfentanil, Alprazolam, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Apixaban, Aprepitant, Argatroban, Aripiprazole, Artemether, Astemizole, Asunaprevir, Atorvastatin, Axitinib, Azelastine, Benidipine, Boceprevir, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Cerivastatin, Cethromycin, Chloroquine, Chlorphenamine, Cilostazol, Cisapride, Clarithromycin, Clonidine, Clopidogrel, Cobicistat, Cocaine, Codeine, Copanlisib, Crizotinib, Cyclophosphamide, Cyclosporine, Daclatasvir, Dapsone, Dasatinib, Deutetrabenazine, Dexamethasone, Dextromethorphan, Diazepam, Diltiazem, Disulfiram, Docetaxel, Domperidone, Dutasteride, Elbasvir, Eplerenone, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Ethosuximide, Etoposide, Felodipine, Fentanyl, Finasteride, Fluoxetine, Flutamide, Fluticasone propionate, Fluvastatin, Granisetron, Halofantrine, Haloperidol, Hydrocortisone, Hydroxyprogesterone caproate, Ibrutinib, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Indinavir, Irinotecan, Isavuconazole, Ivacaftor, Lapatinib, Lercanidipine, Levomethadyl Acetate, Lidocaine, Losartan, Lovastatin, Methadone, Midazolam, Mifepristone, Mycophenolate mofetil, Nateglinide, Nelfinavir, Nevirapine, Nifedipine, Nimodipine, Nisoldipine, Nitrendipine, Norethisterone, Nortriptyline, Ondansetron, Oxazepam, Oxybutynin, Oxycodone, Paclitaxel, Paritaprevir, Pentamidine, Perampanel, Pimozide, Ponatinib, Pravastatin, Praziquantel, Progesterone, Propranolol, Quetiapine, Quinacrine, Quinine, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Salmeterol, Saquinavir, Saxagliptin, Sildenafil, Simvastatin, Sirolimus, Sorafenib, Sulfasalazine, Sunitinib, Tacrolimus, Tamoxifen, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tezacaftor, Trastuzumab emtansine, Trazodone, Tretinoin, Triazolam, Udenafil, Valbenazine, Valproic Acid, Vardenafil, Verapamil, Vicriviroc, Vincristine, Zalcitabine, Zaleplon, Ziprasidone, Zolpidem
2Cytochrome P450 3A5 inducersArmodafinil, Beclomethasone dipropionate, Carbamazepine, Cyclosporine, Daunorubicin, Dexamethasone, Etoposide, Midostaurin, Modafinil, Oxcarbazepine, Phenobarbital, Phenytoin, Reserpine, Rifampicin, Rifapentine, Ritonavir, Thalidomide, Troglitazone
3Cytochrome P450 3A5 inhibitorsAmiodarone, Aprepitant, Boceprevir, Chloramphenicol, Cimetidine, Ciprofloxacin, Clarithromycin, Cobicistat, Crizotinib, Delavirdine, Diltiazem, Elbasvir, Enzalutamide, Fluconazole, Fluticasone propionate, Fluvoxamine, Gestodene, Idelalisib, Imatinib, Indinavir, Isavuconazole, Itraconazole, Ketoconazole, Mibefradil, Mifepristone, Modafinil, Nefazodone, Nelfinavir, Nicardipine, Norfloxacin, Oxymetholone, Phenelzine, Ranitidine, Ritonavir, Rosuvastatin, Rucaparib, Saquinavir, Seproxetine, Telithromycin, Temsirolimus, Troglitazone, Verapamil, Voriconazole
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 1A1 substrate
1Cytochrome P450 1A1 substratesAcetaminophen, Amiodarone, Amodiaquine, Azelastine, Banoxantrone, Carvedilol, Chloroquine, Chlorzoxazone, Cinnarizine, Clenbuterol, Clonidine, Dacarbazine, Dapagliflozin, Dasatinib, Daunorubicin, Debrisoquin, Diclofenac, Dronabinol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flunarizine, Flutamide, Fluvastatin, Gefitinib, Granisetron, Haloperidol, Indirubin, Lorcaserin, Melatonin, Menadione, Nicotine, Oxaliplatin, Pentamidine, Perospirone, Phenacetin, Prazosin, Progesterone, Resveratrol, Riluzole, Riociguat, Romidepsin, Tamoxifen, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Theophylline, Toremifene, Tretinoin, Troglitazone, Warfarin
2Cytochrome P450 1A1 inducersAlbendazole, Bezafibrate, Clofibrate, Clomifene, Clozapine, Dexamethasone, Dicyclomine, Ellagic Acid, Fluorescein, Itraconazole, Ketoconazole, Lansoprazole, Mebendazole, Menadione, Nicotine, Omeprazole, Phenobarbital, Picrotoxin, Primaquine, Quinine, Rabeprazole, Streptozocin, Thiabendazole, Triclocarban, Vitamin A
3Cytochrome P450 1A1 inhibitorsAmlodipine, Arsenic trioxide, Caffeine, Cholecalciferol, Clobetasol propionate, Dexamethasone, Dexmedetomidine, Ellagic Acid, Ethanol, Fluvoxamine, Gefitinib, Isoprenaline, Ketoconazole, Manidipine, Melatonin, Methoxsalen, Mibefradil, Nifedipine, Nitroprusside, Norfloxacin, Ouabain, Propofol, Propranolol, Pyridoxine, Quinidine, Quinine, Resveratrol, Sildenafil, Sulindac, Theophylline, Ticlopidine, Topiroxostat, Vitamin A
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 1A2 substrate
1Cytochrome P450 1A2 substratesAcenocoumarol, Acetaminophen, Albendazole, Almotriptan, Alosetron, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Anagrelide, Antipyrine, Apixaban, Aprepitant, Asenapine, Axitinib, Azelastine, Bendamustine, Benzyl alcohol, Betaxolol, Bortezomib, Bromazepam, Bupivacaine, Bupropion, Caffeine, Carbamazepine, Carmustine, Carvedilol, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Clenbuterol, Clevidipine, Clomipramine, Clonidine, Clopidogrel, Clozapine, Conjugated estrogens, Cyclobenzaprine, Dacarbazine, Dapagliflozin, Dasatinib, Daunorubicin, Desipramine, Deutetrabenazine, Dexfenfluramine, Diazepam, Diclofenac, Dinoprostone, Diphenhydramine, Domperidone, Doxepin, Duloxetine, Eltrombopag, Enasidenib, Ergotamine, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Estrone sulfate, Ethanol, Etoposide, Etoricoxib, Flunarizine, Flunitrazepam, Fluorouracil, Fluoxetine, Flutamide, Fluvoxamine, Frovatriptan, Genistein, Grepafloxacin, Guanabenz, Haloperidol, Hesperetin, Hexobarbital, Icotinib, Iloperidone, Imatinib, Imipramine, Imiquimod, Ixazomib, Leflunomide, Levobupivacaine, Lidocaine, Lofexidine, Lomefloxacin, Lorcaserin, Lumiracoxib, Malathion, Maprotiline, Melatonin, Menadione, Mephenytoin, Methadone, Methoxyflurane, Mexiletine, Mianserin, Mirtazapine, Muraglitazar, Nabumetone, Naproxen, Nicotine, Nifedipine, Nitric Oxide, Nortriptyline, Olanzapine, Omeprazole, Ondansetron, Oxaliplatin, Oxtriphylline, Palonosetron, Pantoprazole, Pazopanib, Pentamidine, Pentoxifylline, Perphenazine, Phenacetin, Pimozide, Pipotiazine, Pomalidomide, Praziquantel, Primaquine, Progesterone, Proguanil, Promazine, Propafenone, Propofol, Propranolol, Pyrazinamide, Quinine, Ramelteon, Ranitidine, Rasagiline, Resveratrol, Rifabutin, Riluzole, Ritonavir, Rizatriptan, Rofecoxib, Ropinirole, Ropivacaine, Rotigotine, Rucaparib, Selegiline, Sertraline, Stiripentol, Tacrine, Tamoxifen, Telithromycin, Temafloxacin, Terbinafine, Thalidomide, Theobromine, Theophylline, Thiabendazole, Thioridazine, Thiothixene, Tizanidine, Tolperisone, Toremifene, Triamterene, Trifluoperazine, Ulipristal, Vadimezan, Verapamil, Voxilaprevir, Warfarin, Zileuton, Ziprasidone, Zolmitriptan, Zolpidem, Zotepine
2Cytochrome P450 1A2 inhibitorsAbiraterone, Acyclovir, Agomelatine, Albendazole, Alitretinoin, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Anastrozole, Apomorphine, Artenimol, Atazanavir, Atropine, Azithromycin, Bortezomib, Bromocriptine, Buprenorphine, Caffeine, Carbamazepine, Carbimazole, Cimetidine, Cimicifuga racemosa, Ciprofloxacin, Citalopram, Clarithromycin, Clobetasol propionate, Clomifene, Clotrimazole, Clozapine, Conjugated estrogens, Crisaborole, Curcumin, Delavirdine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Diacerein, Diazepam, Diclofenac, Disulfiram, Dopamine, Dosulepin, Edetic Acid, Efavirenz, Eltrombopag, Enasidenib, Enoxacin, Entacapone, Epinephrine, Erythromycin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Etoricoxib, Fluconazole, Fluoxetine, Fluphenazine, Flutamide, Fluvastatin, Fluvoxamine, Gemfibrozil, Genistein, Glecaprevir, Glycerol Phenylbutyrate, Imipramine, Interferon Alfa-2b, Recombinant, Interferon gamma-1b, Irbesartan, Isoniazid, Ketoconazole, Levofloxacin, Lidocaine, Lobeglitazone, Lomefloxacin, Lopinavir, Losartan, Manidipine, Meclizine, Melatonin, Mestranol, Methimazole, Methotrimeprazine, Methoxsalen, Mexiletine, Mibefradil, Miconazole, Midostaurin, Mifepristone, Mirtazapine, Moclobemide, Modafinil, Nefazodone, Nelfinavir, Nevirapine, Niclosamide, Nifedipine, Nilvadipine, Nisoldipine, Nitroprusside, Norepinephrine, Norfloxacin, Obeticholic acid, Ofloxacin, Olanzapine, Omeprazole, Ondansetron, Orphenadrine, Oxymetholone, Paroxetine, Pefloxacin, Peginterferon alfa-2a, Peginterferon alfa-2b, Pentoxifylline, Peppermint oil, Perphenazine, Phentermine, Phenylbutyric acid, Phenylpropanolamine, Pibrentasvir, Primaquine, Propafenone, Propofol, Propranolol, Quinidine, Quinine, Ranitidine, Resveratrol, Rhein, Rofecoxib, Ropinirole, Rosiglitazone, Rotigotine, Roxithromycin, Rucaparib, Selegiline, Sertraline, Simeprevir, Sorafenib, Sulconazole, Sulindac, Synthetic Conjugated Estrogens, A, Tegaserod, Temafloxacin, Tenofovir disoproxil, Theophylline, Thiabendazole, Thioridazine, Ticlopidine, Tioconazole, Tocainide, Topiroxostat, Tranylcypromine, Triamterene, Valaciclovir, Valproic Acid, Vemurafenib, Verapamil, Zafirlukast, Zileuton, Zucapsaicin
3Cytochrome P450 1A2 inducersAlbendazole, Aminoglutethimide, Armodafinil, Belinostat, beta-Naphthoflavone, Capsaicin, Carbamazepine, Danthron, Griseofulvin, Insulin Aspart, Insulin Beef, Insulin Detemir, Insulin Glargine, Insulin Glulisine, Insulin Human, Insulin Lispro, Insulin Pork, Lansoprazole, Menadione, Midostaurin, Modafinil, Nafcillin, Nicotine, Omeprazole, Osimertinib, Pantoprazole, Phenobarbital, Phenylephrine, Pitolisant, Primaquine, Primidone, Quinine, Rabeprazole, Resveratrol, Rifampicin, Rilpivirine, Ritonavir, Rucaparib, Secobarbital, Streptozocin
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 1B1 substrate
1Cytochrome P450 1B1 substratesAmodiaquine, Caffeine, Dasatinib, Docetaxel, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flutamide, Melatonin, Oxaliplatin, Procarbazine, Progesterone, Tamoxifen, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline
2Cytochrome P450 1B1 inhibitorsArsenic trioxide, Daunorubicin, Docetaxel, Doxorubicin, Flutamide, Ketoconazole, Melatonin, Mitoxantrone, Paclitaxel, Propofol, Resveratrol, Tamoxifen
3Cytochrome P450 1B1 inducersBiotin, Clozapine, Dexamethasone, Docetaxel, Lansoprazole, Omeprazole, Phenobarbital, Primaquine, Triclocarban
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 2D6 substrate
1Cytochrome P450 2D6 substrates4-Methoxyamphetamine, Acetaminophen, Acetylcholine, Ajmaline, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amiodarone, Amitriptyline, Amoxapine, Amphetamine, Amprenavir, Amsacrine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Artemether, Astemizole, Asunaprevir, Atomoxetine, Azelastine, Benzatropine, Benzyl alcohol, Bepridil, Betaxolol, Bisoprolol, Bortezomib, Brexpiprazole, Brompheniramine, Bufuralol, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Caffeine, Captopril, Cariprazine, Carteolol, Carvedilol, Cephalexin, Cevimeline, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Clozapine, Codeine, Cyclobenzaprine, Cyclophosphamide, Dapagliflozin, Darifenacin, Dasabuvir, Debrisoquin, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine maleate, Dexfenfluramine, Dexmethylphenidate, Dextroamphetamine, Dextromethorphan, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dopamine, Doxazosin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Epinastine, Escitalopram, Esmirtazapine, Ethylmorphine, Etoricoxib, Fesoterodine, Fingolimod, Flecainide, Flunarizine, Fluoxetine, Fluphenazine, Fluvastatin, Fluvoxamine, Formoterol, Galantamine, Gefitinib, Granisetron, Halofantrine, Haloperidol, Halothane, Hydrocodone, Hydromorphone, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Ipecac, Ipratropium, Ixazomib, Labetalol, Letermovir, Levodopa, Levomilnacipran, Lidocaine, Lisuride, Lofexidine, Lomustine, Loperamide, Loratadine, Lorcaserin, Lorpiprazole, Maprotiline, Mephenytoin, Mequitazine, Mesoridazine, Methadone, Methamphetamine, Methotrimeprazine, Methoxyflurane, Methylphenidate, Methyprylon, Metoclopramide, Metoprolol, Mexiletine, Mianserin, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Morphine, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nevirapine, Nicardipine, Nicergoline, Nicotine, Nifedipine, Nitrofural, Nortriptyline, Olanzapine, Ondansetron, Opium, Oxycodone, Oxymorphone, Palonosetron, Paroxetine, Pazopanib, Pentamidine, Perhexiline, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenformin, Pindolol, Piperazine, Pipotiazine, Pitolisant, Ponatinib, Procainamide, Prochlorperazine, Progesterone, Promethazine, Propafenone, Propofol, Propranolol, Protriptyline, Pseudoephedrine, Quetiapine, Quinine, Ranitidine, Remoxipride, Repinotan, Risperidone, Ritonavir, Ropivacaine, Rotigotine, Rucaparib, Rupatadine, Saquinavir, Sertindole, Sertraline, Sildenafil, Simvastatin, Sparteine, Tamoxifen, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Trimipramine, Umeclidinium, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Vortioxetine, Yohimbine, Zalcitabine, Zolpidem, Zuclopenthixol
2Cytochrome P450 2D6 inhibitorsAbiraterone, Acebutolol, Ajmaline, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Amphetamine, Antipyrine, Aripiprazole, Artemether, Artenimol, Asenapine, Atomoxetine, Atorvastatin, Azelastine, Betaxolol, Bicalutamide, Biperiden, Bortezomib, Brompheniramine, Buprenorphine, Bupropion, Carbinoxamine, Carteolol, Celecoxib, Cerivastatin, Chloroquine, Chlorphenamine, Chlorpromazine, Cholecalciferol, Cimetidine, Cimicifuga racemosa, Cinacalcet, Cisapride, Citalopram, Clemastine, Clobazam, Clomipramine, Clotrimazole, Clozapine, Cobicistat, Cocaine, Codeine, Curcumin, Cyclosporine, Cyproterone acetate, Darifenacin, Delavirdine, Deramciclane, Desipramine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Dexmethylphenidate, Dextroamphetamine, Dextromethorphan, Dextropropoxyphene, Diacerein, Diltiazem, Dimethyl sulfoxide, Diphenhydramine, Disulfiram, Dolasetron, Dosulepin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Efavirenz, Eliglustat, Enasidenib, Entacapone, Enzalutamide, Epinastine, Escitalopram, Etoricoxib, Felodipine, Fenfluramine, Fexofenadine, Flecainide, Fluoxetine, Fluphenazine, Fluvastatin, Fluvoxamine, Gefitinib, Glycerol Phenylbutyrate, Granisetron, Halofantrine, Haloperidol, Histamine, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Idarubicin, Imatinib, Imipramine, Indinavir, Indisulam, Irbesartan, Isavuconazole, Isoniazid, Itraconazole, Ketoconazole, Labetalol, Lansoprazole, Lercanidipine, Levosalbutamol, Lidocaine, Lomustine, Lopinavir, Loratadine, Lorcaserin, Lovastatin, Lumefantrine, Manidipine, Mefloquine, Melperone, Mepyramine, Methadone, Methamphetamine, Methazolamide, Methimazole, Methotrimeprazine, Methoxsalen, Methylnaltrexone, Methylphenidate, Metoclopramide, Metoprolol, Mianserin, Mibefradil, Miconazole, Midodrine, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Moclobemide, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Ondansetron, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Pentamidine, Pergolide, Perhexiline, Perphenazine, Phentermine, Phenylbutyric acid, Pimozide, Pindolol, Pioglitazone, Pipotiazine, Pitolisant, Pravastatin, Praziquantel, Primaquine, Proguanil, Promazine, Promethazine, Propafenone, Propofol, Propranolol, Pyrimethamine, Quetiapine, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Risperidone, Ritonavir, Rivastigmine, Rolapitant, Ropinirole, Rosiglitazone, Rotigotine, Rucaparib, Rutin, Saquinavir, Selegiline, Sertraline, Sildenafil, Simvastatin, Sorafenib, Sparteine, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tamoxifen, Tapentadol, Tegaserod, Telithromycin, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticagrelor, Ticlopidine, Timolol, Tioconazole, Tipranavir, Tramadol, Tranylcypromine, Tripelennamine, Triprolidine, Trospium, Vemurafenib, Venlafaxine, Verapamil, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Yohimbine, Zafirlukast, Ziprasidone, Zucapsaicin
3Cytochrome P450 2D6 inducersAripiprazole, Dexamethasone, Glutethimide, Granisetron, Haloperidol, Loratadine, Mirtazapine, Moclobemide, Pindolol, Reboxetine, Rifapentine
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 2C8 substrate
1Cytochrome P450 2C8 substratesAcetaminophen, Acetylsalicylic acid, Almotriptan, Aminophenazone, Amiodarone, Amitriptyline, Amodiaquine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Atorvastatin, Azelastine, Benzyl alcohol, Beraprost, Bioallethrin, Brigatinib, Brompheniramine, Buprenorphine, Bupropion, Cabazitaxel, Caffeine, Carbamazepine, Carbinoxamine, Cerivastatin, Chloroquine, Cisapride, Clozapine, Cyclophosphamide, Dabrafenib, Dapsone, Dasabuvir, Dextromethorphan, Diazepam, Diclofenac, Diltiazem, Domperidone, Eltrombopag, Enasidenib, Enzalutamide, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Eszopiclone, Fluorouracil, Fluvastatin, Fosphenytoin, Halofantrine, Ibuprofen, Ifosfamide, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Lansoprazole, Lapatinib, Levomilnacipran, Licofelone, Lidocaine, Loperamide, Loratadine, Losartan, Mefenamic acid, Meloxicam, Mephenytoin, Methadone, Mirtazapine, Morphine, Muraglitazar, Mycophenolate mofetil, Naloxone, Naproxen, Nicardipine, Nicotine, Odanacatib, Olodaterol, Ombitasvir, Omeprazole, Paclitaxel, Paramethadione, Pazopanib, Pentamidine, Perospirone, Perphenazine, Phenprocoumon, Phenytoin, Pioglitazone, Piroxicam, Pitavastatin, Ponatinib, Progesterone, Propofol, Quinidine, Quinine, Repaglinide, Rifampicin, Riociguat, Rofecoxib, Rosiglitazone, Selegiline, Selexipag, Seratrodast, Simvastatin, Sitagliptin, Sorafenib, Sulfadiazine, Sulfinpyrazone, Tazarotene, Temazepam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline, Tolbutamide, Torasemide, Tretinoin, Trimethadione, Trimethoprim, Troglitazone, Velpatasvir, Verapamil, Vortioxetine, Voxilaprevir, Warfarin, Zafirlukast, Zidovudine, Zopiclone
2Cytochrome P450 2C8 inhibitorsAbiraterone, Amitriptyline, Amlodipine, Atorvastatin, Belinostat, Bezafibrate, Candesartan, Candesartan cilexetil, Carbamazepine, Celecoxib, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Clopidogrel, Clotrimazole, Cocaine, Colchicine, Crisaborole, Cyclosporine, Delavirdine, Dextropropoxyphene, Diethylstilbestrol, Efavirenz, Eltrombopag, Enasidenib, Enzalutamide, Ethinyl Estradiol, Etoposide, Felodipine, Fenofibrate, Fluvastatin, Gemfibrozil, Idelalisib, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Lapatinib, Letermovir, Levothyroxine, Licofelone, Liotrix, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Metronidazole, Midostaurin, Mometasone, Montelukast, Nabilone, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Opicapone, Oxybutynin, Paroxetine, Phenelzine, Pioglitazone, Piperaquine, Piroxicam, Ponatinib, Pravastatin, Propafenone, Pyrimethamine, Quercetin, Quinine, Rabeprazole, Raloxifene, Regorafenib, Rifampicin, Ritonavir, Rosiglitazone, Rucaparib, Rutin, Salmeterol, Saquinavir, Simvastatin, Sorafenib, Spironolactone, Sulfamethoxazole, Sulfaphenazole, Tamoxifen, Tegaserod, Terfenadine, Teriflunomide, Thioridazine, Ticlopidine, Tioconazole, Topiroxostat, Trametinib, Triazolam, Trimethoprim, Troglitazone, Troleandomycin, Valproic Acid, Vismodegib, Warfarin, Zafirlukast
3Cytochrome P450 2C8 inducersCarbamazepine, Colchicine, Cyclophosphamide, Dexamethasone, Fosphenytoin, Gemfibrozil, Hydrocortisone, Ifosfamide, Isavuconazole, Lumacaftor, Midostaurin, Phenobarbital, Primidone, Probenecid, Rifampicin, Rifapentine, Ritonavir, Secobarbital
Interacting GroupInteracting Drugs
Erlotinib is a Cytochrome P450 2C8 inhibitor
1Cytochrome P450 2C8 substratesAcetaminophen, Acetylsalicylic acid, Almotriptan, Aminophenazone, Amiodarone, Amitriptyline, Amodiaquine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Atorvastatin, Azelastine, Benzyl alcohol, Beraprost, Bioallethrin, Brigatinib, Brompheniramine, Buprenorphine, Bupropion, Cabazitaxel, Caffeine, Carbamazepine, Carbinoxamine, Cerivastatin, Chloroquine, Cisapride, Clozapine, Cyclophosphamide, Dabrafenib, Dapsone, Dasabuvir, Dextromethorphan, Diazepam, Diclofenac, Diltiazem, Domperidone, Eltrombopag, Enasidenib, Enzalutamide, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Eszopiclone, Fluorouracil, Fluvastatin, Fosphenytoin, Halofantrine, Ibuprofen, Ifosfamide, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Lansoprazole, Lapatinib, Levomilnacipran, Licofelone, Lidocaine, Loperamide, Loratadine, Losartan, Mefenamic acid, Meloxicam, Mephenytoin, Methadone, Mirtazapine, Morphine, Muraglitazar, Mycophenolate mofetil, Naloxone, Naproxen, Nicardipine, Nicotine, Odanacatib, Olodaterol, Ombitasvir, Omeprazole, Paclitaxel, Paramethadione, Pazopanib, Pentamidine, Perospirone, Perphenazine, Phenprocoumon, Phenytoin, Pioglitazone, Piroxicam, Pitavastatin, Ponatinib, Progesterone, Propofol, Quinidine, Quinine, Repaglinide, Rifampicin, Riociguat, Rofecoxib, Rosiglitazone, Selegiline, Selexipag, Seratrodast, Simvastatin, Sitagliptin, Sorafenib, Sulfadiazine, Sulfinpyrazone, Tazarotene, Temazepam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline, Tolbutamide, Torasemide, Tretinoin, Trimethadione, Trimethoprim, Troglitazone, Velpatasvir, Verapamil, Vortioxetine, Voxilaprevir, Warfarin, Zafirlukast, Zidovudine, Zopiclone
2Cytochrome P450 2C8 inhibitorsAbiraterone, Amitriptyline, Amlodipine, Atorvastatin, Belinostat, Bezafibrate, Candesartan, Candesartan cilexetil, Carbamazepine, Celecoxib, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Clopidogrel, Clotrimazole, Cocaine, Colchicine, Crisaborole, Cyclosporine, Delavirdine, Dextropropoxyphene, Diethylstilbestrol, Efavirenz, Eltrombopag, Enasidenib, Enzalutamide, Ethinyl Estradiol, Etoposide, Felodipine, Fenofibrate, Fluvastatin, Gemfibrozil, Idelalisib, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Lapatinib, Letermovir, Levothyroxine, Licofelone, Liotrix, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Metronidazole, Midostaurin, Mometasone, Montelukast, Nabilone, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Opicapone, Oxybutynin, Paroxetine, Phenelzine, Pioglitazone, Piperaquine, Piroxicam, Ponatinib, Pravastatin, Propafenone, Pyrimethamine, Quercetin, Quinine, Rabeprazole, Raloxifene, Regorafenib, Rifampicin, Ritonavir, Rosiglitazone, Rucaparib, Rutin, Salmeterol, Saquinavir, Simvastatin, Sorafenib, Spironolactone, Sulfamethoxazole, Sulfaphenazole, Tamoxifen, Tegaserod, Terfenadine, Teriflunomide, Thioridazine, Ticlopidine, Tioconazole, Topiroxostat, Trametinib, Triazolam, Trimethoprim, Troglitazone, Troleandomycin, Valproic Acid, Vismodegib, Warfarin, Zafirlukast
3Cytochrome P450 2C8 inducersCarbamazepine, Colchicine, Cyclophosphamide, Dexamethasone, Fosphenytoin, Gemfibrozil, Hydrocortisone, Ifosfamide, Isavuconazole, Lumacaftor, Midostaurin, Phenobarbital, Primidone, Probenecid, Rifampicin, Rifapentine, Ritonavir, Secobarbital
Interacting GroupInteracting Drugs
Erlotinib is a UDP-glucuronosyltransferase 1-1 inhibitor
1UDP-glucuronosyltransferase 1-1 substratesAbacavir, Acetaminophen, Atorvastatin, Axitinib, Bictegravir, Delafloxacin, Diclofenac, Dolutegravir, Eltrombopag, Enasidenib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Etoposide, Ezetimibe, Ezogabine, Flurbiprofen, Fluvastatin, Gavestinel, Ibuprofen, Indacaterol, Indomethacin, Irinotecan, Letermovir, Losartan, Lovastatin, Morphine, Muraglitazar, Mycophenolate mofetil, Mycophenolic acid, Naltrexone, Naproxen, Raltegravir, Simvastatin, Suprofen, Troglitazone
2UDP-glucuronosyltransferase 1-1 inhibitorsAdenine, Enasidenib, Ertugliflozin, Flunitrazepam, Fostamatinib, Glecaprevir, Indomethacin, Nilotinib, Pazopanib, Pibrentasvir, Propofol, Regorafenib, Rucaparib, Sorafenib
3UDP-glucuronosyltransferase 1-1 inducersRifampicin, Testosterone propionate
Interacting GroupInteracting Drugs
Erlotinib is a ATP-binding cassette sub-family G member 2 inhibitor
1ATP-binding cassette sub-family G member 2 substratesAbemaciclib, Afatinib, Alvocidib, Apixaban, Baricitinib, Brigatinib, Camptothecin, Carboplatin, Cerivastatin, Cholesterol, Cisplatin, Cladribine, Clofarabine, Conjugated estrogens, Copanlisib, Dabrafenib, Dactinomycin, Dasatinib, Daunorubicin, Delafloxacin, Docetaxel, Dolutegravir, Doxorubicin, Enasidenib, Ertugliflozin, Etoposide, Ezetimibe, Fluorouracil, Folic Acid, Fostamatinib, Gefitinib, Glecaprevir, Glyburide, Idelalisib, Imatinib, Irinotecan, Ivermectin, Lamivudine, Leflunomide, Lenvatinib, Methotrexate, Mitoxantrone, Mycophenolate mofetil, Nilotinib, Nitrofurantoin, Ombitasvir, Osimertinib, Oxaliplatin, Paclitaxel, Pazopanib, Pibrentasvir, Pitavastatin, Ponatinib, Pravastatin, Prazosin, Riluzole, Riociguat, Rosuvastatin, Rucaparib, Safinamide, Simeprevir, Sofosbuvir, Sorafenib, Sulfasalazine, Sumatriptan, Tamoxifen, Teniposide, Teriflunomide, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Topotecan, Velpatasvir, Vemurafenib, Venetoclax, Vincristine, Voxilaprevir, Zidovudine
2ATP-binding cassette sub-family G member 2 inhibitorsAbemaciclib, Afatinib, Alectinib, Baricitinib, Brigatinib, Buprenorphine, Cabazitaxel, Cannabidiol, Cobicistat, Cyclosporine, Dabrafenib, Daclatasvir, Daidzin, Dasabuvir, Dasatinib, Dexamethasone, Diethylstilbestrol, Doxorubicin, Dronabinol, Elacridar, Enasidenib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Gefitinib, Genistein, Glecaprevir, Glyburide, Hesperetin, Hydrocortisone, Imatinib, Isavuconazole, Lansoprazole, Letermovir, Medical Cannabis, Mitoxantrone, Nabiximols, Naringenin, Nelfinavir, Nilotinib, Novobiocin, Omeprazole, Pantoprazole, Pibrentasvir, Ponatinib, Pravastatin, Prazosin, Quercetin, Rabeprazole, Regorafenib, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Saquinavir, Simeprevir, Sorafenib, Sulfasalazine, Sunitinib, Taurocholic Acid, Telmisartan, Topiroxostat, Topotecan, Vandetanib, Velpatasvir, Verapamil, Vismodegib, Voxilaprevir
3ATP-binding cassette sub-family G member 2 antagonistsAvatrombopag, Zafirlukast
4ATP-binding cassette sub-family G member 2 inducersApalutamide, Venlafaxine
5ATP-binding cassette sub-family G member 2 weak inhibitorsCobimetinib
6ATP-binding cassette sub-family G member 2 transportersLedipasvir
Interacting GroupInteracting Drugs
Erlotinib is a Multidrug resistance protein 1 substrate
1Multidrug resistance protein 1 inducersAldosterone, Amiodarone, Amprenavir, Apalutamide, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Cyclosporine, Daunorubicin, Dexamethasone, Digoxin, Doxorubicin, Estriol, Estrone, Indinavir, Levothyroxine, Liothyronine, Liotrix, Lumacaftor, Midazolam, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Norethisterone, Phenobarbital, Platelet Activating Factor, Progesterone, Reserpine, Rifampicin, Ritonavir, Saquinavir, Sirolimus, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Trazodone, Trimethoprim, Verapamil, Vinblastine, Vincristine
2Multidrug resistance protein 1 substratesAbemaciclib, Acebutolol, Acetaminophen, Acetylsalicylic acid, Afatinib, Aldosterone, Alitretinoin, Ambrisentan, Amitriptyline, Apixaban, Arsenic trioxide, Asunaprevir, Atazanavir, Atenolol, Axitinib, Baricitinib, Belinostat, Benidipine, Betamethasone, Bosutinib, Bromocriptine, Cabazitaxel, Caffeine, Camptothecin, Canagliflozin, Carbamazepine, Carfilzomib, Ceritinib, Cerivastatin, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clobazam, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Dactinomycin, Dapagliflozin, Dasatinib, Daunorubicin, Debrisoquin, Dexamethasone, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxorubicin, Edoxaban, Elbasvir, Eletriptan, Enasidenib, Epinastine, Ertugliflozin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinyl Estradiol, Etoposide, Ezetimibe, Fesoterodine, Fexofenadine, Fidaxomicin, Fluciclovine (18F), Fluticasone furoate, Gefitinib, Gemcitabine, Glecaprevir, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ketazolam, Ketoconazole, Lamivudine, Lamotrigine, Lansoprazole, Lenalidomide, Lenvatinib, Letermovir, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Losartan, Mannitol, Methotrexate, Methylprednisolone, Metoprolol, Midazolam, Mirabegron, Mitoxantrone, Morphine, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nizatidine, Odanacatib, Olanzapine, Ombitasvir, Osimertinib, Paclitaxel, Panobinostat, Pazopanib, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Pomalidomide, Ponatinib, Pravastatin, Prazosin, Prednisolone, Prednisone, Progesterone, Propranolol, Quetiapine, Quinidine, Quinine, Ranitidine, Reserpine, Rifampicin, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Salicylic acid, Saquinavir, Selexipag, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Tacrolimus, Tamoxifen, Taurocholic Acid, Technetium Tc-99m sestamibi, Telaprevir, Temsirolimus, Testosterone propionate, Ticagrelor, Timolol, Tolvaptan, Topotecan, Toremifene, Trastuzumab emtansine, Ubidecarenone, Ulipristal, Umeclidinium, Vecuronium, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vismodegib, Voxilaprevir, Zidovudine
3Multidrug resistance protein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Albendazole, Alectinib, Alfentanil, Amantadine, Aminohippuric acid, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Amsacrine, Astemizole, Atazanavir, Atenolol, Atorvastatin, Azelastine, Azithromycin, Benzocaine, Bepridil, Biperiden, Boceprevir, Bosutinib, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carbamazepine, Carvedilol, Caspofungin, Chloroquine, Chlorpromazine, Chlorpropamide, Chlorprothixene, Cholesterol, Cilazapril, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colchicine, Colforsin, Crizotinib, Curcumin, Cyclophosphamide, Cyclosporine, Daclatasvir, Dactinomycin, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Dexamethasone, Dextromethorphan, Diclofenac, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Doxazosin, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Enalapril, Enasidenib, Enzalutamide, Ergonovine, Ergotamine, Erythromycin, Estramustine, Etoposide, Etravirine, Felodipine, Fentanyl, Fexofenadine, Fidaxomicin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Gefitinib, Genistein, Glecaprevir, Glyburide, Glycerin, Gramicidin D, Grepafloxacin, Haloperidol, Hydrocortisone, Idelalisib, Imatinib, Imipramine, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Itraconazole, Ivacaftor, Ivermectin, Ketamine, Ketoconazole, Lansoprazole, Lapatinib, Letermovir, Levofloxacin, Lidocaine, Lomitapide, Loperamide, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Maprotiline, Mebendazole, Mefloquine, Megestrol acetate, Meprobamate, Methadone, Metoprolol, Mibefradil, Miconazole, Midazolam, Mifepristone, Mitomycin, Mitoxantrone, Morphine, Naltrexone, Naringenin, Nelfinavir, Neostigmine, Nicardipine, Nifedipine, Nilotinib, Nisoldipine, Nitrazepam, Nitrendipine, Omeprazole, P-Nitrophenol, Paclitaxel, Palmitic Acid, Pantoprazole, Paroxetine, Perindopril, Pibrentasvir, Pimozide, Ponatinib, Posaconazole, Pravastatin, Prazosin, Prednisone, Probenecid, Progesterone, Promethazine, Propafenone, Propranolol, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Reboxetine, Regorafenib, Reserpine, Rifampicin, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Saquinavir, Scopolamine, Selegiline, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Spironolactone, Staurosporine, Sulfinpyrazone, Sumatriptan, Sunitinib, Tacrine, Tacrolimus, Tamoxifen, Taurocholic Acid, Telaprevir, Telmisartan, Temsirolimus, Terazosin, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Ticagrelor, Tolvaptan, Trifluoperazine, Triflupromazine, Trimethoprim, Trimipramine, Troleandomycin, Velpatasvir, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voacamine, Voxilaprevir, Zimelidine
4Multidrug resistance protein 1 transportersalpha-Tocopherol acetate, Betrixaban, Ledipasvir, Tocopherol
5Multidrug resistance protein 1 bindersTechnetium Tc-99m tetrofosmin
6Multidrug resistance protein 1 antagonistsTocofersolan