Showing BioInteractions for DB00675 (Tamoxifen)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Tamoxifen is a Estrogen receptor alpha antagonist
1Estrogen receptor alpha agonistsAllylestrenol, Bazedoxifene, Chlorotrianisene, Clomifene, Conjugated estrogens, Danazol, Desogestrel, Dienestrol, Diethylstilbestrol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estriol, Estrone, Estrone sulfate, Ethinyl Estradiol, Ethynodiol diacetate, Etonogestrel, Gestrinone, Lasofoxifene, Medroxyprogesterone acetate, Mestranol, Norgestimate, Ospemifene, Phenolphthalein, Polyestradiol phosphate, Progesterone, Quinestrol, Raloxifene, Tibolone
2Estrogen receptor alpha modulatorsQuinestrol, Toremifene
3Estrogen receptor alpha antagonistsBazedoxifene, Clomifene, Fluoxymesterone, Fulvestrant, Gestrinone, Lasofoxifene, Melatonin, Naloxone, Ospemifene, Tibolone
4Estrogen receptor alpha negative modulatorsLasofoxifene
5Estrogen receptor alpha bindersPrasterone
6Estrogen receptor alpha ligandsSynthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B
7Estrogen receptor alpha cofactorsZinc
Interacting GroupInteracting Drugs
Tamoxifen is a Estrogen receptor alpha agonist
1Estrogen receptor alpha agonistsAllylestrenol, Bazedoxifene, Chlorotrianisene, Clomifene, Conjugated estrogens, Danazol, Desogestrel, Dienestrol, Diethylstilbestrol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estriol, Estrone, Estrone sulfate, Ethinyl Estradiol, Ethynodiol diacetate, Etonogestrel, Gestrinone, Lasofoxifene, Medroxyprogesterone acetate, Mestranol, Norgestimate, Ospemifene, Phenolphthalein, Polyestradiol phosphate, Progesterone, Quinestrol, Raloxifene, Tibolone
2Estrogen receptor alpha modulatorsQuinestrol, Toremifene
3Estrogen receptor alpha antagonistsBazedoxifene, Clomifene, Fluoxymesterone, Fulvestrant, Gestrinone, Lasofoxifene, Melatonin, Naloxone, Ospemifene, Tibolone
4Estrogen receptor alpha negative modulatorsLasofoxifene
5Estrogen receptor alpha bindersPrasterone
6Estrogen receptor alpha ligandsSynthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B
7Estrogen receptor alpha cofactorsZinc
Interacting GroupInteracting Drugs
Tamoxifen is a Estrogen receptor beta antagonist
1Estrogen receptor beta agonists5-Alpha-Androstane-3-Beta,17beta-Diol, Diethylstilbestrol, Equol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone sulfate, Lasofoxifene, Raloxifene
2Estrogen receptor beta activatorsPrasterone
3Estrogen receptor beta partial agonistsNaringenin
Interacting GroupInteracting Drugs
Tamoxifen is a Estrogen receptor beta agonist
1Estrogen receptor beta agonists5-Alpha-Androstane-3-Beta,17beta-Diol, Diethylstilbestrol, Equol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone sulfate, Lasofoxifene, Raloxifene
2Estrogen receptor beta activatorsPrasterone
3Estrogen receptor beta partial agonistsNaringenin
Interacting GroupInteracting Drugs
Tamoxifen is a 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase inhibitor
Interacting GroupInteracting Drugs
Tamoxifen is a Protein kinase C inhibitor
Interacting GroupInteracting Drugs
Tamoxifen is a Potassium voltage-gated channel subfamily H member 2 inhibitor
1Potassium voltage-gated channel subfamily H member 2 inhibitorsAlfuzosin, Amiodarone, Amsacrine, Astemizole, Bepridil, Betrixaban, Carvedilol, Chlorpromazine, Cisapride, Disopyramide, Dofetilide, Doxazosin, Doxepin, Erythromycin, Flecainide, Fluoxetine, Halofantrine, Ibutilide, Imipramine, Isavuconazole, Ketoconazole, Miconazole, Pentoxyverine, Pimozide, Prazosin, Procainamide, Propafenone, Quinidine, Sertindole, Sotalol, Terazosin, Terfenadine, Thioridazine, Verapamil
2Potassium voltage-gated channel subfamily H member 2 blockersPitolisant, Vernakalant
3Potassium voltage-gated channel subfamily H member 2 antagonistsNefazodone
4Potassium voltage-gated channel subfamily H member 2 agonistsPotassium nitrate
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2C9 substrate
1Cytochrome P450 2C9 inhibitorsAbiraterone, Acenocoumarol, Acetyl sulfisoxazole, Agomelatine, Aminophenazone, Amiodarone, Amlodipine, Amodiaquine, Anastrozole, Aprepitant, Armodafinil, Atorvastatin, Atovaquone, Avasimibe, Azelastine, Belinostat, Benzbromarone, Bicalutamide, Bortezomib, Candesartan, Candesartan cilexetil, Capecitabine, Ceritinib, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Cimicifuga racemosa, Cisplatin, Clevidipine, Clopidogrel, Clotrimazole, Clozapine, Cocaine, Colchicine, Crisaborole, Curcumin, Cyclizine, Cyclosporine, Delavirdine, Desloratadine, Dexfenfluramine, Dextropropoxyphene, Diacerein, Diazepam, Diclofenac, Dicoumarol, Diethylstilbestrol, Diltiazem, Disulfiram, Doconexent, Dosulepin, Efavirenz, Enasidenib, Epinephrine, Eprosartan, Ethanol, Etodolac, Etoricoxib, Etravirine, Felbamate, Felodipine, Fenofibrate, Flecainide, Floxuridine, Fluconazole, Fluorouracil, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Ginkgo biloba, Glyburide, Histamine, Ibuprofen, Imatinib, Indinavir, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Leflunomide, Lifitegrast, Lobeglitazone, Lopinavir, Loratadine, Lornoxicam, Losartan, Lovastatin, Lumacaftor, Manidipine, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Methazolamide, Methimazole, Metronidazole, Miconazole, Midostaurin, Moclobemide, Modafinil, Nabilone, Nelfinavir, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Noscapine, Olanzapine, Omeprazole, Pantoprazole, Parecoxib, Paroxetine, Phentermine, Phenylbutazone, Phenytoin, Pioglitazone, Piperine, Piroxicam, Pranlukast, Pravastatin, Probenecid, Progesterone, Promethazine, Propafenone, Propofol, Pyrimethamine, Quinidine, Quinine, Rabeprazole, Regorafenib, Rhein, Ritonavir, Rosiglitazone, Rosuvastatin, Rucaparib, Rutin, Saquinavir, Selegiline, Seratrodast, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulconazole, Sulfadiazine, Sulfadimethoxine, Sulfamethizole, Sulfamethoxazole, Sulfamoxole, Sulfanilamide, Sulfaphenazole, Sulfapyridine, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tegaserod, Teniposide, Thioridazine, Ticagrelor, Ticlopidine, Tioconazole, Tolcapone, Topiroxostat, Tranylcypromine, Triazolam, Trimethoprim, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Verapamil, Vismodegib, Voriconazole, Warfarin, Zafirlukast, Zucapsaicin
2Cytochrome P450 2C9 substratesAceclofenac, Acenocoumarol, Acetaminophen, Acetyl sulfisoxazole, Acetylsalicylic acid, Alosetron, Alprazolam, Aminophenazone, Amitriptyline, Amprenavir, Antipyrine, Apixaban, Arachidonic Acid, Arformoterol, Artemether, Asunaprevir, Atazanavir, Azelastine, Bexarotene, Bioallethrin, Bortezomib, Bosentan, Brivaracetam, Brompheniramine, Buprenorphine, Bupropion, Cabozantinib, Caffeine, Candesartan, Candesartan cilexetil, Cannabidiol, Carbinoxamine, Carvedilol, Celecoxib, Chlorpropamide, Cinnarizine, Cisapride, Clopidogrel, Clozapine, Cyclophosphamide, Dapagliflozin, Dapsone, Dextromethorphan, Diazepam, Diclofenac, Dicoumarol, Diltiazem, Diphenhydramine, Doconexent, Dolasetron, Donepezil, Dopamine, Dorzolamide, Doxepin, Dronabinol, Eletriptan, Enasidenib, Epoprostenol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Eszopiclone, Etodolac, Etoricoxib, Etravirine, Fluindione, Flunarizine, Flunitrazepam, Fluoxetine, Flurbiprofen, Fluvastatin, Formoterol, Fosphenytoin, Gavestinel, Gliclazide, Glimepiride, Glipizide, Glyburide, Guanfacine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydromorphone, Ibuprofen, Idarubicin, Ifosfamide, Imatinib, Indisulam, Indomethacin, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Ketoprofen, Lansoprazole, Leflunomide, Lesinurad, Licofelone, Lidocaine, Loratadine, Lornoxicam, Losartan, Lumiracoxib, Medical Cannabis, Mefenamic acid, Melatonin, Meloxicam, Mephenytoin, Mestranol, Methadone, Methoxyflurane, Metronidazole, Mirtazapine, Moclobemide, Montelukast, Nabiximols, Naproxen, Nateglinide, Netupitant, Nevirapine, Niclosamide, Nicotine, Nortriptyline, Olodaterol, Omeprazole, Ondansetron, Ospemifene, Oxaprozin, Paclitaxel, Paramethadione, Parecoxib, Perphenazine, Phenacetin, Phenobarbital, Phenprocoumon, Phenylbutazone, Phenytoin, Pioglitazone, Piperaquine, Piroxicam, Pitavastatin, Prasugrel, Pravastatin, Progesterone, Proguanil, Promazine, Propofol, Quazepam, Quinidine, Quinine, Rifampicin, Rofecoxib, Rosiglitazone, Rosuvastatin, Rupatadine, Salicylic acid, Selegiline, Seratrodast, Sertraline, Sildenafil, Sitaxentan, Sulfamethoxazole, Sulfamoxole, Sulfinpyrazone, Suprofen, Tapentadol, Temazepam, Tenoxicam, Terbinafine, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Theophylline, Thiamylal, Tolbutamide, Tolterodine, Torasemide, Trabectedin, Treprostinil, Tretinoin, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Venlafaxine, Verapamil, Vicriviroc, Vismodegib, Voriconazole, Vortioxetine, Warfarin, Ximelagatran, Zafirlukast, Zalcitabine, Zaltoprofen, Zidovudine, Zileuton, Zolpidem, Zopiclone
3Cytochrome P450 2C9 inducersApalutamide, Aprepitant, Atorvastatin, Avatrombopag, Bosentan, Carbamazepine, Cerivastatin, Colchicine, Cyclophosphamide, Dapsone, Delafloxacin, Dexamethasone, Diclofenamide, Enzalutamide, Estrone sulfate, Fluvastatin, Fosphenytoin, Ifosfamide, Isavuconazole, Lansoprazole, Letermovir, Lovastatin, Lumacaftor, Midostaurin, Modafinil, Nicardipine, Nifedipine, Nilotinib, Phenobarbital, Phentermine, Phenytoin, Primidone, Rifampicin, Rifapentine, Ritonavir, Secobarbital, Seratrodast, Simvastatin
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2C9 inhibitor
1Cytochrome P450 2C9 inhibitorsAbiraterone, Acenocoumarol, Acetyl sulfisoxazole, Agomelatine, Aminophenazone, Amiodarone, Amlodipine, Amodiaquine, Anastrozole, Aprepitant, Armodafinil, Atorvastatin, Atovaquone, Avasimibe, Azelastine, Belinostat, Benzbromarone, Bicalutamide, Bortezomib, Candesartan, Candesartan cilexetil, Capecitabine, Ceritinib, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Cimicifuga racemosa, Cisplatin, Clevidipine, Clopidogrel, Clotrimazole, Clozapine, Cocaine, Colchicine, Crisaborole, Curcumin, Cyclizine, Cyclosporine, Delavirdine, Desloratadine, Dexfenfluramine, Dextropropoxyphene, Diacerein, Diazepam, Diclofenac, Dicoumarol, Diethylstilbestrol, Diltiazem, Disulfiram, Doconexent, Dosulepin, Efavirenz, Enasidenib, Epinephrine, Eprosartan, Ethanol, Etodolac, Etoricoxib, Etravirine, Felbamate, Felodipine, Fenofibrate, Flecainide, Floxuridine, Fluconazole, Fluorouracil, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Ginkgo biloba, Glyburide, Histamine, Ibuprofen, Imatinib, Indinavir, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Leflunomide, Lifitegrast, Lobeglitazone, Lopinavir, Loratadine, Lornoxicam, Losartan, Lovastatin, Lumacaftor, Manidipine, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Methazolamide, Methimazole, Metronidazole, Miconazole, Midostaurin, Moclobemide, Modafinil, Nabilone, Nelfinavir, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Noscapine, Olanzapine, Omeprazole, Pantoprazole, Parecoxib, Paroxetine, Phentermine, Phenylbutazone, Phenytoin, Pioglitazone, Piperine, Piroxicam, Pranlukast, Pravastatin, Probenecid, Progesterone, Promethazine, Propafenone, Propofol, Pyrimethamine, Quinidine, Quinine, Rabeprazole, Regorafenib, Rhein, Ritonavir, Rosiglitazone, Rosuvastatin, Rucaparib, Rutin, Saquinavir, Selegiline, Seratrodast, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulconazole, Sulfadiazine, Sulfadimethoxine, Sulfamethizole, Sulfamethoxazole, Sulfamoxole, Sulfanilamide, Sulfaphenazole, Sulfapyridine, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tegaserod, Teniposide, Thioridazine, Ticagrelor, Ticlopidine, Tioconazole, Tolcapone, Topiroxostat, Tranylcypromine, Triazolam, Trimethoprim, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Verapamil, Vismodegib, Voriconazole, Warfarin, Zafirlukast, Zucapsaicin
2Cytochrome P450 2C9 substratesAceclofenac, Acenocoumarol, Acetaminophen, Acetyl sulfisoxazole, Acetylsalicylic acid, Alosetron, Alprazolam, Aminophenazone, Amitriptyline, Amprenavir, Antipyrine, Apixaban, Arachidonic Acid, Arformoterol, Artemether, Asunaprevir, Atazanavir, Azelastine, Bexarotene, Bioallethrin, Bortezomib, Bosentan, Brivaracetam, Brompheniramine, Buprenorphine, Bupropion, Cabozantinib, Caffeine, Candesartan, Candesartan cilexetil, Cannabidiol, Carbinoxamine, Carvedilol, Celecoxib, Chlorpropamide, Cinnarizine, Cisapride, Clopidogrel, Clozapine, Cyclophosphamide, Dapagliflozin, Dapsone, Dextromethorphan, Diazepam, Diclofenac, Dicoumarol, Diltiazem, Diphenhydramine, Doconexent, Dolasetron, Donepezil, Dopamine, Dorzolamide, Doxepin, Dronabinol, Eletriptan, Enasidenib, Epoprostenol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Eszopiclone, Etodolac, Etoricoxib, Etravirine, Fluindione, Flunarizine, Flunitrazepam, Fluoxetine, Flurbiprofen, Fluvastatin, Formoterol, Fosphenytoin, Gavestinel, Gliclazide, Glimepiride, Glipizide, Glyburide, Guanfacine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydromorphone, Ibuprofen, Idarubicin, Ifosfamide, Imatinib, Indisulam, Indomethacin, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Ketoprofen, Lansoprazole, Leflunomide, Lesinurad, Licofelone, Lidocaine, Loratadine, Lornoxicam, Losartan, Lumiracoxib, Medical Cannabis, Mefenamic acid, Melatonin, Meloxicam, Mephenytoin, Mestranol, Methadone, Methoxyflurane, Metronidazole, Mirtazapine, Moclobemide, Montelukast, Nabiximols, Naproxen, Nateglinide, Netupitant, Nevirapine, Niclosamide, Nicotine, Nortriptyline, Olodaterol, Omeprazole, Ondansetron, Ospemifene, Oxaprozin, Paclitaxel, Paramethadione, Parecoxib, Perphenazine, Phenacetin, Phenobarbital, Phenprocoumon, Phenylbutazone, Phenytoin, Pioglitazone, Piperaquine, Piroxicam, Pitavastatin, Prasugrel, Pravastatin, Progesterone, Proguanil, Promazine, Propofol, Quazepam, Quinidine, Quinine, Rifampicin, Rofecoxib, Rosiglitazone, Rosuvastatin, Rupatadine, Salicylic acid, Selegiline, Seratrodast, Sertraline, Sildenafil, Sitaxentan, Sulfamethoxazole, Sulfamoxole, Sulfinpyrazone, Suprofen, Tapentadol, Temazepam, Tenoxicam, Terbinafine, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Theophylline, Thiamylal, Tolbutamide, Tolterodine, Torasemide, Trabectedin, Treprostinil, Tretinoin, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Venlafaxine, Verapamil, Vicriviroc, Vismodegib, Voriconazole, Vortioxetine, Warfarin, Ximelagatran, Zafirlukast, Zalcitabine, Zaltoprofen, Zidovudine, Zileuton, Zolpidem, Zopiclone
3Cytochrome P450 2C9 inducersApalutamide, Aprepitant, Atorvastatin, Avatrombopag, Bosentan, Carbamazepine, Cerivastatin, Colchicine, Cyclophosphamide, Dapsone, Delafloxacin, Dexamethasone, Diclofenamide, Enzalutamide, Estrone sulfate, Fluvastatin, Fosphenytoin, Ifosfamide, Isavuconazole, Lansoprazole, Letermovir, Lovastatin, Lumacaftor, Midostaurin, Modafinil, Nicardipine, Nifedipine, Nilotinib, Phenobarbital, Phentermine, Phenytoin, Primidone, Rifampicin, Rifapentine, Ritonavir, Secobarbital, Seratrodast, Simvastatin
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 3A4 substrate
1Cytochrome P450 3A4 substratesAbemaciclib, Abiraterone, Acenocoumarol, Acetaminophen, Adinazolam, Albendazole, Alfentanil, Alfuzosin, Aliskiren, Allylestrenol, Almotriptan, Alogliptin, Alosetron, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Argatroban, Aripiprazole, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Avanafil, Axitinib, Azelastine, Azithromycin, Banoxantrone, Baricitinib, Bedaquiline, Benidipine, Benzphetamine, Benzyl alcohol, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromazepam, Bromocriptine, Brompheniramine, Budesonide, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Busulfan, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calcitriol, Canagliflozin, Cannabidiol, Carbamazepine, Carbinoxamine, Cariprazine, Carvedilol, Celecoxib, Celiprolol, Cephalexin, Cerivastatin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Cilostazol, Cinacalcet, Cisapride, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clofibrate, clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepate, Clotiazepam, Clozapine, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cytarabine, Dabrafenib, Daclatasvir, Dantrolene, Dapagliflozin, Dapsone, Darifenacin, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexchlorpheniramine maleate, Dexlansoprazole, Dextromethorphan, Dextropropoxyphene, Diazepam, Diclofenac, Dienogest, Digitoxin, Digoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergotamine, Diltiazem, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Dorzolamide, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Dutasteride, Efavirenz, Elbasvir, Eletriptan, Eliglustat, Elvitegravir, Enalapril, Enasidenib, Enzalutamide, Epinastine, Eplerenone, Ergocalciferol, Ergoloid mesylate, Ergonovine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esomeprazole, Estazolam, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrogens, esterified, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinyl Estradiol, Ethosuximide, Ethylmorphine, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Everolimus, Exemestane, Famciclovir, Felbamate, Felodipine, Fenofibrate, Fentanyl, Fesoterodine, Finasteride, Fingolimod, Flibanserin, Flunisolide, Flunitrazepam, Fluorometholone, Fluoxetine, Flurazepam, Flutamide, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fosamprenavir, Fosnetupitant, Fostamatinib, Fulvestrant, Galantamine, Gefitinib, Gemfibrozil, Glipizide, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halofantrine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydrocodone, Hydrocortisone, Hydromorphone, Hydroxyprogesterone caproate, Ibrutinib, Icotinib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indapamide, Indinavir, Ipecac, Ipratropium, Irinotecan, Isavuconazole, Isavuconazonium, Isosorbide Dinitrate, Isosorbide Mononitrate, Isradipine, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lansoprazole, Lapatinib, Laquinimod, Lenvatinib, Lercanidipine, Letrozole, Levobupivacaine, Levocetirizine, Levomethadyl Acetate, Levomilnacipran, Levonorgestrel, Levothyroxine, Lidocaine, Lisuride, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorcaserin, Lorpiprazole, Losartan, Lovastatin, Lumefantrine, Lurasidone, Lysergic Acid Diethylamide, Macimorelin, Macitentan, Maraviroc, Mebendazole, Medical Cannabis, Medroxyprogesterone acetate, Mefloquine, Meloxicam, Mestranol, Methadone, Methaqualone, Methoxsalen, Methoxyflurane, Methylergometrine, Methylprednisolone, Methyltestosterone, Metronidazole, Mexiletine, Mianserin, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Modafinil, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naloxegol, Naloxone, Naltrexone, Nateglinide, Nefazodone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nicotine, Nifedipine, Nilotinib, Nilvadipine, Nimodipine, Nisoldipine, Nitrazepam, Nitrendipine, Norethisterone, Norgestrel, Nortriptyline, Odanacatib, Olaparib, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Ospemifene, Oxazepam, Oxybutynin, Oxycodone, Oxymorphone, Paclitaxel, Palbociclib, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Pazopanib, Pentamidine, Perampanel, Pergolide, Perhexiline, Permethrin, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenoxybenzamine, Phenprocoumon, Phenytoin, Pilocarpine, Pimecrolimus, Pimozide, Pinacidil, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Podofilox, Pomalidomide, Ponatinib, Posaconazole, Prasterone, Prasugrel, Pravastatin, Prazepam, Praziquantel, Prednisolone, Prednisone, Primaquine, Prochlorperazine, Progesterone, Proguanil, Promazine, Propafenone, Propiverine, Propofol, Propranolol, Pyrazinamide, Quazepam, Quetiapine, Quinacrine, Quinidine, Quinine, Rabeprazole, Raloxifene, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Retapamulin, Rifabutin, Rifampicin, Rilpivirine, Rimonabant, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Rofecoxib, Rolapitant, Romidepsin, Ropinirole, Ropivacaine, Rosuvastatin, Rotigotine, Roxithromycin, Rucaparib, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Selegiline, Selexipag, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, Spiramycin, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamsulosin, Tasosartan, Taurochenodeoxycholic acid, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Teniposide, Terbinafine, Terfenadine, Terguride, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tezacaftor, Theophylline, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Ticlopidine, Tinidazole, Tiotropium, Tipranavir, Tocofersolan, Tocopherol, Tofacitinib, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Troleandomycin, Udenafil, Ulipristal, Valbenazine, Valdecoxib, Valproic Acid, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vismodegib, Voriconazole, Vortioxetine, Voxilaprevir, Warfarin, Yohimbine, Zafirlukast, Zalcitabine, Zaleplon, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine
2Cytochrome P450 3A4 inhibitorsAcetaminophen, Acetazolamide, Acetyl sulfisoxazole, Aldesleukin, Ambroxol, Amiodarone, Amprenavir, Anastrozole, Antipyrine, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, Atomoxetine, Azelastine, Azithromycin, Betamethasone, Bifonazole, Boceprevir, Bortezomib, Brentuximab vedotin, Bromocriptine, Buprenorphine, Cabergoline, Caffeine, Capsaicin, Caspofungin, Ceritinib, Cerivastatin, Chloramphenicol, Chlorzoxazone, Cimetidine, Cimicifuga racemosa, Ciprofloxacin, Cisapride, Clarithromycin, Clemastine, Clindamycin, Clofazimine, Clomifene, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cocaine, Colchicine, Conivaptan, Cortisone acetate, Crizotinib, Curcumin, Cyclophosphamide, Cyclosporine, Dalfopristin, Danazol, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Dexamethasone, Dextropropoxyphene, Diazepam, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Docetaxel, Doxorubicin, Doxycycline, Dronedarone, Econazole, Efavirenz, Efonidipine, Elbasvir, Enasidenib, Epinephrine, Ergonovine, Ergotamine, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fentanyl, Fluconazole, Fluoxetine, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Gemfibrozil, Glyburide, Haloperidol, Histamine, Hydralazine, Hydrocortisone, Idelalisib, Ifosfamide, Imatinib, Indinavir, Indisulam, Irbesartan, Irinotecan, Isavuconazole, Isavuconazonium, Isoniazid, Itraconazole, Ivacaftor, Josamycin, Ketazolam, Ketoconazole, Lansoprazole, Lapatinib, Lercanidipine, Levofloxacin, Levosalbutamol, Lidocaine, Linagliptin, Lomitapide, Lomustine, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Manidipine, Mefloquine, Mequitazine, Methadone, Methazolamide, Methimazole, Methylergometrine, Methylprednisolone, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirtazapine, Mitoxantrone, Modafinil, Naloxone, Nefazodone, Nelfinavir, Netupitant, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nisoldipine, Nitrendipine, Nitric Oxide, Norfloxacin, Noscapine, Olanzapine, Olaparib, Omeprazole, Orphenadrine, Oxetacaine, Oxybutynin, Oxymetholone, Paclitaxel, Palbociclib, Paramethasone, Pazopanib, Peppermint oil, Pergolide, Phenelzine, Pilocarpine, Pimozide, Piperaquine, Posaconazole, Pravastatin, Prednisolone, Prednisone, Primaquine, Progesterone, Propofol, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Regorafenib, Repaglinide, Resveratrol, Rilpivirine, Risperidone, Ritonavir, Rivastigmine, Rolitetracycline, Rosuvastatin, Roxithromycin, Rucaparib, Rutin, Salbutamol, Saquinavir, Sarilumab, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sitaxentan, Sorafenib, Stiripentol, Sulfamethoxazole, Sulfanilamide, Sulfinpyrazone, Sulfisoxazole, Tacrolimus, Tadalafil, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Thiopental, Ticlopidine, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Tramadol, Tranylcypromine, Troglitazone, Troleandomycin, Valproic Acid, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voriconazole, Zafirlukast, Ziprasidone
3Cytochrome P450 3A4 inducersAcetaminophen, Alimemazine, Aminoglutethimide, Apalutamide, Armodafinil, Artemether, Atorvastatin, Azatadine, Bexarotene, Bosentan, Calcitriol, Carbamazepine, Cefradine, Cerivastatin, Chlorphenesin, Clarithromycin, Clevidipine, Clobazam, Clofibrate, Clotrimazole, Clozapine, Colchicine, Cyclophosphamide, Dabrafenib, Deferasirox, Delafloxacin, Desvenlafaxine, Dexamethasone, Dicloxacillin, Drospirenone, Efavirenz, Eletriptan, Enasidenib, Enzalutamide, Eslicarbazepine acetate, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Fluvastatin, Fosaprepitant, Fosphenytoin, Gemfibrozil, Glycerol Phenylbutyrate, Griseofulvin, Guanethidine, Hydrocortamate, Hydrocortisone, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Lansoprazole, Loratadine, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Metamizole, Methadone, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Pantoprazole, Pegvisomant, Pentobarbital, Perampanel, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Prednisone, Primidone, Probenecid, Progesterone, Pyridostigmine, Quinidine, Quinine, Rifabutin, Rifampicin, Rifapentine, Rifaximin, Rilpivirine, Ritonavir, Rofecoxib, Rufinamide, Seratrodast, St. John's Wort, Sulfinpyrazone, Temozolomide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Topiramate, Topotecan, Trametinib, Troglitazone, Vemurafenib
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 3A4 inhibitor
1Cytochrome P450 3A4 substratesAbemaciclib, Abiraterone, Acenocoumarol, Acetaminophen, Adinazolam, Albendazole, Alfentanil, Alfuzosin, Aliskiren, Allylestrenol, Almotriptan, Alogliptin, Alosetron, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Argatroban, Aripiprazole, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Avanafil, Axitinib, Azelastine, Azithromycin, Banoxantrone, Baricitinib, Bedaquiline, Benidipine, Benzphetamine, Benzyl alcohol, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromazepam, Bromocriptine, Brompheniramine, Budesonide, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Busulfan, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calcitriol, Canagliflozin, Cannabidiol, Carbamazepine, Carbinoxamine, Cariprazine, Carvedilol, Celecoxib, Celiprolol, Cephalexin, Cerivastatin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Cilostazol, Cinacalcet, Cisapride, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clofibrate, clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepate, Clotiazepam, Clozapine, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cytarabine, Dabrafenib, Daclatasvir, Dantrolene, Dapagliflozin, Dapsone, Darifenacin, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexchlorpheniramine maleate, Dexlansoprazole, Dextromethorphan, Dextropropoxyphene, Diazepam, Diclofenac, Dienogest, Digitoxin, Digoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergotamine, Diltiazem, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Dorzolamide, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Dutasteride, Efavirenz, Elbasvir, Eletriptan, Eliglustat, Elvitegravir, Enalapril, Enasidenib, Enzalutamide, Epinastine, Eplerenone, Ergocalciferol, Ergoloid mesylate, Ergonovine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esomeprazole, Estazolam, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrogens, esterified, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinyl Estradiol, Ethosuximide, Ethylmorphine, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Everolimus, Exemestane, Famciclovir, Felbamate, Felodipine, Fenofibrate, Fentanyl, Fesoterodine, Finasteride, Fingolimod, Flibanserin, Flunisolide, Flunitrazepam, Fluorometholone, Fluoxetine, Flurazepam, Flutamide, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fosamprenavir, Fosnetupitant, Fostamatinib, Fulvestrant, Galantamine, Gefitinib, Gemfibrozil, Glipizide, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halofantrine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydrocodone, Hydrocortisone, Hydromorphone, Hydroxyprogesterone caproate, Ibrutinib, Icotinib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indapamide, Indinavir, Ipecac, Ipratropium, Irinotecan, Isavuconazole, Isavuconazonium, Isosorbide Dinitrate, Isosorbide Mononitrate, Isradipine, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lansoprazole, Lapatinib, Laquinimod, Lenvatinib, Lercanidipine, Letrozole, Levobupivacaine, Levocetirizine, Levomethadyl Acetate, Levomilnacipran, Levonorgestrel, Levothyroxine, Lidocaine, Lisuride, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorcaserin, Lorpiprazole, Losartan, Lovastatin, Lumefantrine, Lurasidone, Lysergic Acid Diethylamide, Macimorelin, Macitentan, Maraviroc, Mebendazole, Medical Cannabis, Medroxyprogesterone acetate, Mefloquine, Meloxicam, Mestranol, Methadone, Methaqualone, Methoxsalen, Methoxyflurane, Methylergometrine, Methylprednisolone, Methyltestosterone, Metronidazole, Mexiletine, Mianserin, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Modafinil, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naloxegol, Naloxone, Naltrexone, Nateglinide, Nefazodone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nicotine, Nifedipine, Nilotinib, Nilvadipine, Nimodipine, Nisoldipine, Nitrazepam, Nitrendipine, Norethisterone, Norgestrel, Nortriptyline, Odanacatib, Olaparib, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Ospemifene, Oxazepam, Oxybutynin, Oxycodone, Oxymorphone, Paclitaxel, Palbociclib, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Pazopanib, Pentamidine, Perampanel, Pergolide, Perhexiline, Permethrin, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenoxybenzamine, Phenprocoumon, Phenytoin, Pilocarpine, Pimecrolimus, Pimozide, Pinacidil, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Podofilox, Pomalidomide, Ponatinib, Posaconazole, Prasterone, Prasugrel, Pravastatin, Prazepam, Praziquantel, Prednisolone, Prednisone, Primaquine, Prochlorperazine, Progesterone, Proguanil, Promazine, Propafenone, Propiverine, Propofol, Propranolol, Pyrazinamide, Quazepam, Quetiapine, Quinacrine, Quinidine, Quinine, Rabeprazole, Raloxifene, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Retapamulin, Rifabutin, Rifampicin, Rilpivirine, Rimonabant, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Rofecoxib, Rolapitant, Romidepsin, Ropinirole, Ropivacaine, Rosuvastatin, Rotigotine, Roxithromycin, Rucaparib, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Selegiline, Selexipag, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, Spiramycin, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamsulosin, Tasosartan, Taurochenodeoxycholic acid, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Teniposide, Terbinafine, Terfenadine, Terguride, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tezacaftor, Theophylline, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Ticlopidine, Tinidazole, Tiotropium, Tipranavir, Tocofersolan, Tocopherol, Tofacitinib, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Troleandomycin, Udenafil, Ulipristal, Valbenazine, Valdecoxib, Valproic Acid, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vismodegib, Voriconazole, Vortioxetine, Voxilaprevir, Warfarin, Yohimbine, Zafirlukast, Zalcitabine, Zaleplon, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine
2Cytochrome P450 3A4 inhibitorsAcetaminophen, Acetazolamide, Acetyl sulfisoxazole, Aldesleukin, Ambroxol, Amiodarone, Amprenavir, Anastrozole, Antipyrine, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, Atomoxetine, Azelastine, Azithromycin, Betamethasone, Bifonazole, Boceprevir, Bortezomib, Brentuximab vedotin, Bromocriptine, Buprenorphine, Cabergoline, Caffeine, Capsaicin, Caspofungin, Ceritinib, Cerivastatin, Chloramphenicol, Chlorzoxazone, Cimetidine, Cimicifuga racemosa, Ciprofloxacin, Cisapride, Clarithromycin, Clemastine, Clindamycin, Clofazimine, Clomifene, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cocaine, Colchicine, Conivaptan, Cortisone acetate, Crizotinib, Curcumin, Cyclophosphamide, Cyclosporine, Dalfopristin, Danazol, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Dexamethasone, Dextropropoxyphene, Diazepam, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Docetaxel, Doxorubicin, Doxycycline, Dronedarone, Econazole, Efavirenz, Efonidipine, Elbasvir, Enasidenib, Epinephrine, Ergonovine, Ergotamine, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fentanyl, Fluconazole, Fluoxetine, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Gemfibrozil, Glyburide, Haloperidol, Histamine, Hydralazine, Hydrocortisone, Idelalisib, Ifosfamide, Imatinib, Indinavir, Indisulam, Irbesartan, Irinotecan, Isavuconazole, Isavuconazonium, Isoniazid, Itraconazole, Ivacaftor, Josamycin, Ketazolam, Ketoconazole, Lansoprazole, Lapatinib, Lercanidipine, Levofloxacin, Levosalbutamol, Lidocaine, Linagliptin, Lomitapide, Lomustine, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Manidipine, Mefloquine, Mequitazine, Methadone, Methazolamide, Methimazole, Methylergometrine, Methylprednisolone, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirtazapine, Mitoxantrone, Modafinil, Naloxone, Nefazodone, Nelfinavir, Netupitant, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nisoldipine, Nitrendipine, Nitric Oxide, Norfloxacin, Noscapine, Olanzapine, Olaparib, Omeprazole, Orphenadrine, Oxetacaine, Oxybutynin, Oxymetholone, Paclitaxel, Palbociclib, Paramethasone, Pazopanib, Peppermint oil, Pergolide, Phenelzine, Pilocarpine, Pimozide, Piperaquine, Posaconazole, Pravastatin, Prednisolone, Prednisone, Primaquine, Progesterone, Propofol, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Regorafenib, Repaglinide, Resveratrol, Rilpivirine, Risperidone, Ritonavir, Rivastigmine, Rolitetracycline, Rosuvastatin, Roxithromycin, Rucaparib, Rutin, Salbutamol, Saquinavir, Sarilumab, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sitaxentan, Sorafenib, Stiripentol, Sulfamethoxazole, Sulfanilamide, Sulfinpyrazone, Sulfisoxazole, Tacrolimus, Tadalafil, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Thiopental, Ticlopidine, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Tramadol, Tranylcypromine, Troglitazone, Troleandomycin, Valproic Acid, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voriconazole, Zafirlukast, Ziprasidone
3Cytochrome P450 3A4 inducersAcetaminophen, Alimemazine, Aminoglutethimide, Apalutamide, Armodafinil, Artemether, Atorvastatin, Azatadine, Bexarotene, Bosentan, Calcitriol, Carbamazepine, Cefradine, Cerivastatin, Chlorphenesin, Clarithromycin, Clevidipine, Clobazam, Clofibrate, Clotrimazole, Clozapine, Colchicine, Cyclophosphamide, Dabrafenib, Deferasirox, Delafloxacin, Desvenlafaxine, Dexamethasone, Dicloxacillin, Drospirenone, Efavirenz, Eletriptan, Enasidenib, Enzalutamide, Eslicarbazepine acetate, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Fluvastatin, Fosaprepitant, Fosphenytoin, Gemfibrozil, Glycerol Phenylbutyrate, Griseofulvin, Guanethidine, Hydrocortamate, Hydrocortisone, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Lansoprazole, Loratadine, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Metamizole, Methadone, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Pantoprazole, Pegvisomant, Pentobarbital, Perampanel, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Prednisone, Primidone, Probenecid, Progesterone, Pyridostigmine, Quinidine, Quinine, Rifabutin, Rifampicin, Rifapentine, Rifaximin, Rilpivirine, Ritonavir, Rofecoxib, Rufinamide, Seratrodast, St. John's Wort, Sulfinpyrazone, Temozolomide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Topiramate, Topotecan, Trametinib, Troglitazone, Vemurafenib
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 3A4 inducer
1Cytochrome P450 3A4 substratesAbemaciclib, Abiraterone, Acenocoumarol, Acetaminophen, Adinazolam, Albendazole, Alfentanil, Alfuzosin, Aliskiren, Allylestrenol, Almotriptan, Alogliptin, Alosetron, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Argatroban, Aripiprazole, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Avanafil, Axitinib, Azelastine, Azithromycin, Banoxantrone, Baricitinib, Bedaquiline, Benidipine, Benzphetamine, Benzyl alcohol, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromazepam, Bromocriptine, Brompheniramine, Budesonide, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Busulfan, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calcitriol, Canagliflozin, Cannabidiol, Carbamazepine, Carbinoxamine, Cariprazine, Carvedilol, Celecoxib, Celiprolol, Cephalexin, Cerivastatin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Cilostazol, Cinacalcet, Cisapride, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clofibrate, clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepate, Clotiazepam, Clozapine, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cytarabine, Dabrafenib, Daclatasvir, Dantrolene, Dapagliflozin, Dapsone, Darifenacin, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexchlorpheniramine maleate, Dexlansoprazole, Dextromethorphan, Dextropropoxyphene, Diazepam, Diclofenac, Dienogest, Digitoxin, Digoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergotamine, Diltiazem, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Dorzolamide, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Dutasteride, Efavirenz, Elbasvir, Eletriptan, Eliglustat, Elvitegravir, Enalapril, Enasidenib, Enzalutamide, Epinastine, Eplerenone, Ergocalciferol, Ergoloid mesylate, Ergonovine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esomeprazole, Estazolam, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrogens, esterified, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinyl Estradiol, Ethosuximide, Ethylmorphine, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Everolimus, Exemestane, Famciclovir, Felbamate, Felodipine, Fenofibrate, Fentanyl, Fesoterodine, Finasteride, Fingolimod, Flibanserin, Flunisolide, Flunitrazepam, Fluorometholone, Fluoxetine, Flurazepam, Flutamide, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fosamprenavir, Fosnetupitant, Fostamatinib, Fulvestrant, Galantamine, Gefitinib, Gemfibrozil, Glipizide, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halofantrine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydrocodone, Hydrocortisone, Hydromorphone, Hydroxyprogesterone caproate, Ibrutinib, Icotinib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indapamide, Indinavir, Ipecac, Ipratropium, Irinotecan, Isavuconazole, Isavuconazonium, Isosorbide Dinitrate, Isosorbide Mononitrate, Isradipine, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lansoprazole, Lapatinib, Laquinimod, Lenvatinib, Lercanidipine, Letrozole, Levobupivacaine, Levocetirizine, Levomethadyl Acetate, Levomilnacipran, Levonorgestrel, Levothyroxine, Lidocaine, Lisuride, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorcaserin, Lorpiprazole, Losartan, Lovastatin, Lumefantrine, Lurasidone, Lysergic Acid Diethylamide, Macimorelin, Macitentan, Maraviroc, Mebendazole, Medical Cannabis, Medroxyprogesterone acetate, Mefloquine, Meloxicam, Mestranol, Methadone, Methaqualone, Methoxsalen, Methoxyflurane, Methylergometrine, Methylprednisolone, Methyltestosterone, Metronidazole, Mexiletine, Mianserin, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Modafinil, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naloxegol, Naloxone, Naltrexone, Nateglinide, Nefazodone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nicotine, Nifedipine, Nilotinib, Nilvadipine, Nimodipine, Nisoldipine, Nitrazepam, Nitrendipine, Norethisterone, Norgestrel, Nortriptyline, Odanacatib, Olaparib, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Ospemifene, Oxazepam, Oxybutynin, Oxycodone, Oxymorphone, Paclitaxel, Palbociclib, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Pazopanib, Pentamidine, Perampanel, Pergolide, Perhexiline, Permethrin, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenoxybenzamine, Phenprocoumon, Phenytoin, Pilocarpine, Pimecrolimus, Pimozide, Pinacidil, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Podofilox, Pomalidomide, Ponatinib, Posaconazole, Prasterone, Prasugrel, Pravastatin, Prazepam, Praziquantel, Prednisolone, Prednisone, Primaquine, Prochlorperazine, Progesterone, Proguanil, Promazine, Propafenone, Propiverine, Propofol, Propranolol, Pyrazinamide, Quazepam, Quetiapine, Quinacrine, Quinidine, Quinine, Rabeprazole, Raloxifene, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Retapamulin, Rifabutin, Rifampicin, Rilpivirine, Rimonabant, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Rofecoxib, Rolapitant, Romidepsin, Ropinirole, Ropivacaine, Rosuvastatin, Rotigotine, Roxithromycin, Rucaparib, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Selegiline, Selexipag, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, Spiramycin, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamsulosin, Tasosartan, Taurochenodeoxycholic acid, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Teniposide, Terbinafine, Terfenadine, Terguride, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tezacaftor, Theophylline, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Ticlopidine, Tinidazole, Tiotropium, Tipranavir, Tocofersolan, Tocopherol, Tofacitinib, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Troleandomycin, Udenafil, Ulipristal, Valbenazine, Valdecoxib, Valproic Acid, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vismodegib, Voriconazole, Vortioxetine, Voxilaprevir, Warfarin, Yohimbine, Zafirlukast, Zalcitabine, Zaleplon, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine
2Cytochrome P450 3A4 inhibitorsAcetaminophen, Acetazolamide, Acetyl sulfisoxazole, Aldesleukin, Ambroxol, Amiodarone, Amprenavir, Anastrozole, Antipyrine, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, Atomoxetine, Azelastine, Azithromycin, Betamethasone, Bifonazole, Boceprevir, Bortezomib, Brentuximab vedotin, Bromocriptine, Buprenorphine, Cabergoline, Caffeine, Capsaicin, Caspofungin, Ceritinib, Cerivastatin, Chloramphenicol, Chlorzoxazone, Cimetidine, Cimicifuga racemosa, Ciprofloxacin, Cisapride, Clarithromycin, Clemastine, Clindamycin, Clofazimine, Clomifene, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cocaine, Colchicine, Conivaptan, Cortisone acetate, Crizotinib, Curcumin, Cyclophosphamide, Cyclosporine, Dalfopristin, Danazol, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Dexamethasone, Dextropropoxyphene, Diazepam, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Docetaxel, Doxorubicin, Doxycycline, Dronedarone, Econazole, Efavirenz, Efonidipine, Elbasvir, Enasidenib, Epinephrine, Ergonovine, Ergotamine, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fentanyl, Fluconazole, Fluoxetine, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Gemfibrozil, Glyburide, Haloperidol, Histamine, Hydralazine, Hydrocortisone, Idelalisib, Ifosfamide, Imatinib, Indinavir, Indisulam, Irbesartan, Irinotecan, Isavuconazole, Isavuconazonium, Isoniazid, Itraconazole, Ivacaftor, Josamycin, Ketazolam, Ketoconazole, Lansoprazole, Lapatinib, Lercanidipine, Levofloxacin, Levosalbutamol, Lidocaine, Linagliptin, Lomitapide, Lomustine, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Manidipine, Mefloquine, Mequitazine, Methadone, Methazolamide, Methimazole, Methylergometrine, Methylprednisolone, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirtazapine, Mitoxantrone, Modafinil, Naloxone, Nefazodone, Nelfinavir, Netupitant, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nisoldipine, Nitrendipine, Nitric Oxide, Norfloxacin, Noscapine, Olanzapine, Olaparib, Omeprazole, Orphenadrine, Oxetacaine, Oxybutynin, Oxymetholone, Paclitaxel, Palbociclib, Paramethasone, Pazopanib, Peppermint oil, Pergolide, Phenelzine, Pilocarpine, Pimozide, Piperaquine, Posaconazole, Pravastatin, Prednisolone, Prednisone, Primaquine, Progesterone, Propofol, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Regorafenib, Repaglinide, Resveratrol, Rilpivirine, Risperidone, Ritonavir, Rivastigmine, Rolitetracycline, Rosuvastatin, Roxithromycin, Rucaparib, Rutin, Salbutamol, Saquinavir, Sarilumab, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sitaxentan, Sorafenib, Stiripentol, Sulfamethoxazole, Sulfanilamide, Sulfinpyrazone, Sulfisoxazole, Tacrolimus, Tadalafil, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Thiopental, Ticlopidine, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Tramadol, Tranylcypromine, Troglitazone, Troleandomycin, Valproic Acid, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voriconazole, Zafirlukast, Ziprasidone
3Cytochrome P450 3A4 inducersAcetaminophen, Alimemazine, Aminoglutethimide, Apalutamide, Armodafinil, Artemether, Atorvastatin, Azatadine, Bexarotene, Bosentan, Calcitriol, Carbamazepine, Cefradine, Cerivastatin, Chlorphenesin, Clarithromycin, Clevidipine, Clobazam, Clofibrate, Clotrimazole, Clozapine, Colchicine, Cyclophosphamide, Dabrafenib, Deferasirox, Delafloxacin, Desvenlafaxine, Dexamethasone, Dicloxacillin, Drospirenone, Efavirenz, Eletriptan, Enasidenib, Enzalutamide, Eslicarbazepine acetate, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Fluvastatin, Fosaprepitant, Fosphenytoin, Gemfibrozil, Glycerol Phenylbutyrate, Griseofulvin, Guanethidine, Hydrocortamate, Hydrocortisone, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Lansoprazole, Loratadine, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Metamizole, Methadone, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Pantoprazole, Pegvisomant, Pentobarbital, Perampanel, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Prednisone, Primidone, Probenecid, Progesterone, Pyridostigmine, Quinidine, Quinine, Rifabutin, Rifampicin, Rifapentine, Rifaximin, Rilpivirine, Ritonavir, Rofecoxib, Rufinamide, Seratrodast, St. John's Wort, Sulfinpyrazone, Temozolomide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Topiramate, Topotecan, Trametinib, Troglitazone, Vemurafenib
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2D6 substrate
1Cytochrome P450 2D6 substrates4-Methoxyamphetamine, Acetaminophen, Acetylcholine, Ajmaline, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amiodarone, Amitriptyline, Amoxapine, Amphetamine, Amprenavir, Amsacrine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Artemether, Astemizole, Asunaprevir, Atomoxetine, Azelastine, Benzatropine, Benzyl alcohol, Bepridil, Betaxolol, Bisoprolol, Bortezomib, Brexpiprazole, Brompheniramine, Bufuralol, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Caffeine, Captopril, Cariprazine, Carteolol, Carvedilol, Cephalexin, Cevimeline, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Clozapine, Codeine, Cyclobenzaprine, Cyclophosphamide, Dapagliflozin, Darifenacin, Dasabuvir, Debrisoquin, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine maleate, Dexfenfluramine, Dexmethylphenidate, Dextroamphetamine, Dextromethorphan, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dopamine, Doxazosin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Epinastine, Erlotinib, Escitalopram, Esmirtazapine, Ethylmorphine, Etoricoxib, Fesoterodine, Fingolimod, Flecainide, Flunarizine, Fluoxetine, Fluphenazine, Fluvastatin, Fluvoxamine, Formoterol, Galantamine, Gefitinib, Granisetron, Halofantrine, Haloperidol, Halothane, Hydrocodone, Hydromorphone, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Ipecac, Ipratropium, Ixazomib, Labetalol, Letermovir, Levodopa, Levomilnacipran, Lidocaine, Lisuride, Lofexidine, Lomustine, Loperamide, Loratadine, Lorcaserin, Lorpiprazole, Lysergic Acid Diethylamide, Maprotiline, Mephenytoin, Mequitazine, Mesoridazine, Methadone, Methamphetamine, Methotrimeprazine, Methoxyflurane, Methylphenidate, Methyprylon, Metoclopramide, Metoprolol, Mexiletine, Mianserin, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Morphine, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nevirapine, Nicardipine, Nicergoline, Nicotine, Nifedipine, Nitrofural, Nortriptyline, Olanzapine, Ondansetron, Opium, Oxycodone, Oxymorphone, Palonosetron, Paroxetine, Pazopanib, Pentamidine, Perhexiline, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenformin, Pindolol, Piperazine, Pipotiazine, Pitolisant, Ponatinib, Procainamide, Prochlorperazine, Progesterone, Promethazine, Propafenone, Propofol, Propranolol, Protriptyline, Pseudoephedrine, Quetiapine, Quinine, Ranitidine, Remoxipride, Repinotan, Risperidone, Ritonavir, Ropivacaine, Rotigotine, Rucaparib, Rupatadine, Saquinavir, Sertindole, Sertraline, Sildenafil, Simvastatin, Sparteine, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Trimipramine, Umeclidinium, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Vortioxetine, Yohimbine, Zalcitabine, Zolpidem, Zuclopenthixol
2Cytochrome P450 2D6 inhibitorsAbiraterone, Acebutolol, Ajmaline, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Amphetamine, Antipyrine, Aripiprazole, Artemether, Artenimol, Asenapine, Atomoxetine, Atorvastatin, Azelastine, Betaxolol, Bicalutamide, Biperiden, Brompheniramine, Buprenorphine, Bupropion, Carbinoxamine, Carteolol, Celecoxib, Cerivastatin, Chloroquine, Chlorphenamine, Chlorpromazine, Cholecalciferol, Cimetidine, Cimicifuga racemosa, Cinacalcet, Cisapride, Citalopram, Clemastine, Clobazam, Clomipramine, Clotrimazole, Clozapine, Cobicistat, Cocaine, Curcumin, Cyclosporine, Darifenacin, Delavirdine, Deramciclane, Desipramine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Dexmethylphenidate, Dextroamphetamine, Dextropropoxyphene, Diacerein, Dimethyl sulfoxide, Diphenhydramine, Dosulepin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Efavirenz, Eliglustat, Enasidenib, Entacapone, Enzalutamide, Epinastine, Escitalopram, Etoricoxib, Felodipine, Fenfluramine, Fexofenadine, Fluoxetine, Fluphenazine, Fluvoxamine, Glycerol Phenylbutyrate, Granisetron, Halofantrine, Haloperidol, Histamine, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Idarubicin, Imatinib, Imipramine, Indinavir, Indisulam, Isavuconazole, Isoniazid, Itraconazole, Ketoconazole, Labetalol, Lansoprazole, Lercanidipine, Levosalbutamol, Lidocaine, Lopinavir, Loratadine, Lorcaserin, Lovastatin, Lumefantrine, Manidipine, Mefloquine, Melperone, Mepyramine, Methadone, Methamphetamine, Methazolamide, Methimazole, Methotrimeprazine, Methylnaltrexone, Methylphenidate, Metoclopramide, Metoprolol, Mianserin, Mibefradil, Miconazole, Midodrine, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Moclobemide, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Pergolide, Perhexiline, Perphenazine, Phentermine, Phenylbutyric acid, Pimozide, Pindolol, Pioglitazone, Pipotiazine, Pitolisant, Primaquine, Proguanil, Promazine, Promethazine, Propafenone, Propranolol, Pyrimethamine, Quetiapine, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Risperidone, Ritonavir, Rivastigmine, Rolapitant, Ropinirole, Rosiglitazone, Rotigotine, Rucaparib, Rutin, Saquinavir, Selegiline, Sertraline, Sildenafil, Sorafenib, Sparteine, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tapentadol, Tegaserod, Telithromycin, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticagrelor, Ticlopidine, Tipranavir, Tramadol, Tranylcypromine, Tripelennamine, Trospium, Vemurafenib, Venlafaxine, Verapamil, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Yohimbine, Ziprasidone
3Cytochrome P450 2D6 inducersAripiprazole, Dexamethasone, Glutethimide, Granisetron, Haloperidol, Loratadine, Mirtazapine, Moclobemide, Pindolol, Reboxetine, Rifapentine
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2D6 inhibitor
1Cytochrome P450 2D6 substrates4-Methoxyamphetamine, Acetaminophen, Acetylcholine, Ajmaline, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amiodarone, Amitriptyline, Amoxapine, Amphetamine, Amprenavir, Amsacrine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Artemether, Astemizole, Asunaprevir, Atomoxetine, Azelastine, Benzatropine, Benzyl alcohol, Bepridil, Betaxolol, Bisoprolol, Bortezomib, Brexpiprazole, Brompheniramine, Bufuralol, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Caffeine, Captopril, Cariprazine, Carteolol, Carvedilol, Cephalexin, Cevimeline, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Clozapine, Codeine, Cyclobenzaprine, Cyclophosphamide, Dapagliflozin, Darifenacin, Dasabuvir, Debrisoquin, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine maleate, Dexfenfluramine, Dexmethylphenidate, Dextroamphetamine, Dextromethorphan, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dopamine, Doxazosin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Epinastine, Erlotinib, Escitalopram, Esmirtazapine, Ethylmorphine, Etoricoxib, Fesoterodine, Fingolimod, Flecainide, Flunarizine, Fluoxetine, Fluphenazine, Fluvastatin, Fluvoxamine, Formoterol, Galantamine, Gefitinib, Granisetron, Halofantrine, Haloperidol, Halothane, Hydrocodone, Hydromorphone, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Ipecac, Ipratropium, Ixazomib, Labetalol, Letermovir, Levodopa, Levomilnacipran, Lidocaine, Lisuride, Lofexidine, Lomustine, Loperamide, Loratadine, Lorcaserin, Lorpiprazole, Lysergic Acid Diethylamide, Maprotiline, Mephenytoin, Mequitazine, Mesoridazine, Methadone, Methamphetamine, Methotrimeprazine, Methoxyflurane, Methylphenidate, Methyprylon, Metoclopramide, Metoprolol, Mexiletine, Mianserin, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Morphine, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nevirapine, Nicardipine, Nicergoline, Nicotine, Nifedipine, Nitrofural, Nortriptyline, Olanzapine, Ondansetron, Opium, Oxycodone, Oxymorphone, Palonosetron, Paroxetine, Pazopanib, Pentamidine, Perhexiline, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenformin, Pindolol, Piperazine, Pipotiazine, Pitolisant, Ponatinib, Procainamide, Prochlorperazine, Progesterone, Promethazine, Propafenone, Propofol, Propranolol, Protriptyline, Pseudoephedrine, Quetiapine, Quinine, Ranitidine, Remoxipride, Repinotan, Risperidone, Ritonavir, Ropivacaine, Rotigotine, Rucaparib, Rupatadine, Saquinavir, Sertindole, Sertraline, Sildenafil, Simvastatin, Sparteine, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Trimipramine, Umeclidinium, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Vortioxetine, Yohimbine, Zalcitabine, Zolpidem, Zuclopenthixol
2Cytochrome P450 2D6 inhibitorsAbiraterone, Acebutolol, Ajmaline, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Amphetamine, Antipyrine, Aripiprazole, Artemether, Artenimol, Asenapine, Atomoxetine, Atorvastatin, Azelastine, Betaxolol, Bicalutamide, Biperiden, Brompheniramine, Buprenorphine, Bupropion, Carbinoxamine, Carteolol, Celecoxib, Cerivastatin, Chloroquine, Chlorphenamine, Chlorpromazine, Cholecalciferol, Cimetidine, Cimicifuga racemosa, Cinacalcet, Cisapride, Citalopram, Clemastine, Clobazam, Clomipramine, Clotrimazole, Clozapine, Cobicistat, Cocaine, Curcumin, Cyclosporine, Darifenacin, Delavirdine, Deramciclane, Desipramine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Dexmethylphenidate, Dextroamphetamine, Dextropropoxyphene, Diacerein, Dimethyl sulfoxide, Diphenhydramine, Dosulepin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Efavirenz, Eliglustat, Enasidenib, Entacapone, Enzalutamide, Epinastine, Escitalopram, Etoricoxib, Felodipine, Fenfluramine, Fexofenadine, Fluoxetine, Fluphenazine, Fluvoxamine, Glycerol Phenylbutyrate, Granisetron, Halofantrine, Haloperidol, Histamine, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Idarubicin, Imatinib, Imipramine, Indinavir, Indisulam, Isavuconazole, Isoniazid, Itraconazole, Ketoconazole, Labetalol, Lansoprazole, Lercanidipine, Levosalbutamol, Lidocaine, Lopinavir, Loratadine, Lorcaserin, Lovastatin, Lumefantrine, Manidipine, Mefloquine, Melperone, Mepyramine, Methadone, Methamphetamine, Methazolamide, Methimazole, Methotrimeprazine, Methylnaltrexone, Methylphenidate, Metoclopramide, Metoprolol, Mianserin, Mibefradil, Miconazole, Midodrine, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Moclobemide, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Pergolide, Perhexiline, Perphenazine, Phentermine, Phenylbutyric acid, Pimozide, Pindolol, Pioglitazone, Pipotiazine, Pitolisant, Primaquine, Proguanil, Promazine, Promethazine, Propafenone, Propranolol, Pyrimethamine, Quetiapine, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Risperidone, Ritonavir, Rivastigmine, Rolapitant, Ropinirole, Rosiglitazone, Rotigotine, Rucaparib, Rutin, Saquinavir, Selegiline, Sertraline, Sildenafil, Sorafenib, Sparteine, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tapentadol, Tegaserod, Telithromycin, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticagrelor, Ticlopidine, Tipranavir, Tramadol, Tranylcypromine, Tripelennamine, Trospium, Vemurafenib, Venlafaxine, Verapamil, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Yohimbine, Ziprasidone
3Cytochrome P450 2D6 inducersAripiprazole, Dexamethasone, Glutethimide, Granisetron, Haloperidol, Loratadine, Mirtazapine, Moclobemide, Pindolol, Reboxetine, Rifapentine
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2C8 inhibitor
1Cytochrome P450 2C8 substratesAcetaminophen, Acetylsalicylic acid, Almotriptan, Aminophenazone, Amiodarone, Amitriptyline, Amodiaquine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Atorvastatin, Azelastine, Benzyl alcohol, Beraprost, Bioallethrin, Brigatinib, Brompheniramine, Buprenorphine, Bupropion, Cabazitaxel, Caffeine, Carbamazepine, Carbinoxamine, Cerivastatin, Chloroquine, Cisapride, Clozapine, Cyclophosphamide, Dabrafenib, Dapsone, Dasabuvir, Dextromethorphan, Diazepam, Diclofenac, Diltiazem, Domperidone, Eltrombopag, Enasidenib, Enzalutamide, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Eszopiclone, Fluorouracil, Fluvastatin, Halofantrine, Ibuprofen, Ifosfamide, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Lansoprazole, Lapatinib, Levomilnacipran, Licofelone, Lidocaine, Loperamide, Loratadine, Losartan, Mefenamic acid, Meloxicam, Mephenytoin, Methadone, Mirtazapine, Morphine, Muraglitazar, Mycophenolate mofetil, Naloxone, Naproxen, Nicardipine, Nicotine, Odanacatib, Olodaterol, Ombitasvir, Omeprazole, Paclitaxel, Paramethadione, Pazopanib, Pentamidine, Perospirone, Perphenazine, Phenprocoumon, Phenytoin, Pioglitazone, Piroxicam, Pitavastatin, Ponatinib, Progesterone, Propofol, Quinidine, Quinine, Repaglinide, Rifampicin, Riociguat, Rofecoxib, Rosiglitazone, Selegiline, Selexipag, Seratrodast, Simvastatin, Sitagliptin, Sorafenib, Sulfadiazine, Sulfinpyrazone, Tazarotene, Temazepam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline, Tolbutamide, Torasemide, Tretinoin, Trimethadione, Trimethoprim, Troglitazone, Velpatasvir, Verapamil, Vortioxetine, Voxilaprevir, Warfarin, Zafirlukast, Zidovudine, Zopiclone
2Cytochrome P450 2C8 inhibitorsAbiraterone, Amitriptyline, Amlodipine, Atorvastatin, Belinostat, Bezafibrate, Candesartan, Candesartan cilexetil, Celecoxib, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Clopidogrel, Clotrimazole, Cocaine, Colchicine, Crisaborole, Cyclosporine, Delavirdine, Dextropropoxyphene, Diethylstilbestrol, Efavirenz, Eltrombopag, Enasidenib, Enzalutamide, Erlotinib, Ethinyl Estradiol, Etoposide, Felodipine, Fenofibrate, Fluvastatin, Fluvoxamine, Gemfibrozil, Idelalisib, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Lapatinib, Letermovir, Levothyroxine, Licofelone, Liotrix, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Metronidazole, Midostaurin, Mometasone, Montelukast, Nabilone, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Opicapone, Oxybutynin, Paroxetine, Phenelzine, Pioglitazone, Piroxicam, Ponatinib, Pravastatin, Propafenone, Pyrimethamine, Quercetin, Quinine, Rabeprazole, Raloxifene, Regorafenib, Ritonavir, Rosiglitazone, Rucaparib, Rutin, Salmeterol, Saquinavir, Simvastatin, Sorafenib, Spironolactone, Sulfamethoxazole, Sulfaphenazole, Tegaserod, Terfenadine, Teriflunomide, Thioridazine, Ticlopidine, Tioconazole, Topiroxostat, Trametinib, Triazolam, Trimethoprim, Troglitazone, Troleandomycin, Valproic Acid, Vismodegib, Warfarin, Zafirlukast
3Cytochrome P450 2C8 inducersAvatrombopag, Carbamazepine, Colchicine, Cyclophosphamide, Dexamethasone, Gemfibrozil, Hydrocortisone, Ifosfamide, Isavuconazole, Lumacaftor, Midostaurin, Nilotinib, Phenobarbital, Primidone, Probenecid, Rifampicin, Rifapentine, Ritonavir, Secobarbital
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2B6 substrate
1Cytochrome P450 2B6 substratesAmitriptyline, Antipyrine, Artemether, Artemisinin, Asunaprevir, Banoxantrone, Benzphetamine, Benzyl alcohol, Brivaracetam, Brompheniramine, Bupropion, Carbinoxamine, Cinnarizine, Cisapride, Clobazam, clomethiazole, Clopidogrel, Clotiazepam, Cyclophosphamide, Dextromethorphan, Diazepam, Diclofenac, Diphenhydramine, Domperidone, Efavirenz, Enasidenib, Epinastine, Erythromycin, Estrone, Ethylmorphine, Flunarizine, Flunitrazepam, Fluoxetine, Halothane, Ifosfamide, Imipramine, Irinotecan, Isoflurane, Ixazomib, Ketamine, Ketobemidone, Lidocaine, Loperamide, Lorcaserin, Malathion, Mephenytoin, Methadone, Methoxyflurane, Methylphenobarbital, Methyltestosterone, Mexiletine, Mianserin, Midazolam, Nevirapine, Nicotine, Ospemifene, Perhexiline, Permethrin, Perphenazine, Pethidine, Prasugrel, Promethazine, Propofol, Ritonavir, Romidepsin, Ropivacaine, Selegiline, Seratrodast, Sertraline, Sevoflurane, Sorafenib, Temazepam, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tramadol, Tretinoin, Valproic Acid, Velpatasvir, Verapamil, Vortioxetine
2Cytochrome P450 2B6 inducersArmodafinil, Artemether, Atorvastatin, Carbamazepine, Cerivastatin, Clofibrate, Clotrimazole, Cyclophosphamide, Dexamethasone, Efavirenz, Enasidenib, Fluvastatin, Fosphenytoin, Idelalisib, Isavuconazole, Isoflurane, Letermovir, Lumacaftor, Metamizole, Midostaurin, Modafinil, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Olaparib, Orphenadrine, Permethrin, Phenobarbital, Phenytoin, Pitolisant, Primidone, Rifampicin, Ritonavir, Simvastatin, Sulfinpyrazone, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Troglitazone, Verapamil
3Cytochrome P450 2B6 inhibitorsAmlodipine, Amprenavir, Antipyrine, Azelastine, Bupropion, Cholecalciferol, Cisplatin, Citalopram, Clopidogrel, Clotrimazole, Colchicine, Crisaborole, Crizotinib, Curcumin, Desipramine, Doxorubicin, Efavirenz, Enasidenib, Enzalutamide, Ethanol, Fluvoxamine, Isoflurane, Itraconazole, Ketoconazole, Lopinavir, Manidipine, Memantine, Methimazole, Miconazole, Modafinil, Nelfinavir, Nitric Oxide, Orphenadrine, Paroxetine, Phencyclidine, Piperaquine, Quazepam, Quinidine, Raloxifene, Regorafenib, Rilpivirine, Ritonavir, Roxithromycin, Sertraline, Sorafenib, Sulfaphenazole, Thiotepa, Ticlopidine, Venlafaxine, Voriconazole
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2B6 inhibitor
1Cytochrome P450 2B6 substratesAmitriptyline, Antipyrine, Artemether, Artemisinin, Asunaprevir, Banoxantrone, Benzphetamine, Benzyl alcohol, Brivaracetam, Brompheniramine, Bupropion, Carbinoxamine, Cinnarizine, Cisapride, Clobazam, clomethiazole, Clopidogrel, Clotiazepam, Cyclophosphamide, Dextromethorphan, Diazepam, Diclofenac, Diphenhydramine, Domperidone, Efavirenz, Enasidenib, Epinastine, Erythromycin, Estrone, Ethylmorphine, Flunarizine, Flunitrazepam, Fluoxetine, Halothane, Ifosfamide, Imipramine, Irinotecan, Isoflurane, Ixazomib, Ketamine, Ketobemidone, Lidocaine, Loperamide, Lorcaserin, Malathion, Mephenytoin, Methadone, Methoxyflurane, Methylphenobarbital, Methyltestosterone, Mexiletine, Mianserin, Midazolam, Nevirapine, Nicotine, Ospemifene, Perhexiline, Permethrin, Perphenazine, Pethidine, Prasugrel, Promethazine, Propofol, Ritonavir, Romidepsin, Ropivacaine, Selegiline, Seratrodast, Sertraline, Sevoflurane, Sorafenib, Temazepam, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tramadol, Tretinoin, Valproic Acid, Velpatasvir, Verapamil, Vortioxetine
2Cytochrome P450 2B6 inducersArmodafinil, Artemether, Atorvastatin, Carbamazepine, Cerivastatin, Clofibrate, Clotrimazole, Cyclophosphamide, Dexamethasone, Efavirenz, Enasidenib, Fluvastatin, Fosphenytoin, Idelalisib, Isavuconazole, Isoflurane, Letermovir, Lumacaftor, Metamizole, Midostaurin, Modafinil, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Olaparib, Orphenadrine, Permethrin, Phenobarbital, Phenytoin, Pitolisant, Primidone, Rifampicin, Ritonavir, Simvastatin, Sulfinpyrazone, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Troglitazone, Verapamil
3Cytochrome P450 2B6 inhibitorsAmlodipine, Amprenavir, Antipyrine, Azelastine, Bupropion, Cholecalciferol, Cisplatin, Citalopram, Clopidogrel, Clotrimazole, Colchicine, Crisaborole, Crizotinib, Curcumin, Desipramine, Doxorubicin, Efavirenz, Enasidenib, Enzalutamide, Ethanol, Fluvoxamine, Isoflurane, Itraconazole, Ketoconazole, Lopinavir, Manidipine, Memantine, Methimazole, Miconazole, Modafinil, Nelfinavir, Nitric Oxide, Orphenadrine, Paroxetine, Phencyclidine, Piperaquine, Quazepam, Quinidine, Raloxifene, Regorafenib, Rilpivirine, Ritonavir, Roxithromycin, Sertraline, Sorafenib, Sulfaphenazole, Thiotepa, Ticlopidine, Venlafaxine, Voriconazole
Interacting GroupInteracting Drugs
Tamoxifen is a Liver carboxylesterase 1 inhibitor
1Liver carboxylesterase 1 substratesCapecitabine, Ciclesonide, Clopidogrel, Dabigatran etexilate, Homatropine, Indomethacin, Irinotecan, Mycophenolate mofetil, Phenylacetic acid, Propoxycaine, Rufinamide, Selexipag, Trandolapril
2Liver carboxylesterase 1 inhibitorsBenzocaine, Mevastatin
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 3A5 substrate
1Cytochrome P450 3A5 substratesAlfentanil, Alprazolam, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Apixaban, Aprepitant, Argatroban, Aripiprazole, Artemether, Astemizole, Asunaprevir, Atorvastatin, Axitinib, Azelastine, Benidipine, Boceprevir, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Cerivastatin, Cethromycin, Chloroquine, Chlorphenamine, Cilostazol, Cisapride, Clarithromycin, Clonidine, Clopidogrel, Cobicistat, Cocaine, Codeine, Copanlisib, Crizotinib, Cyclophosphamide, Cyclosporine, Daclatasvir, Dapsone, Dasatinib, Deutetrabenazine, Dexamethasone, Dextromethorphan, Diazepam, Diltiazem, Disulfiram, Docetaxel, Domperidone, Dutasteride, Elbasvir, Eplerenone, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Ethosuximide, Etoposide, Felodipine, Fentanyl, Finasteride, Fluoxetine, Flutamide, Fluticasone propionate, Fluvastatin, Granisetron, Halofantrine, Haloperidol, Hydrocortisone, Hydroxyprogesterone caproate, Ibrutinib, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Indinavir, Irinotecan, Isavuconazole, Ivacaftor, Lapatinib, Lercanidipine, Levomethadyl Acetate, Lidocaine, Losartan, Lovastatin, Methadone, Midazolam, Mifepristone, Mycophenolate mofetil, Nateglinide, Nelfinavir, Nevirapine, Nifedipine, Nimodipine, Nisoldipine, Nitrendipine, Norethisterone, Nortriptyline, Ondansetron, Oxazepam, Oxybutynin, Oxycodone, Paclitaxel, Paritaprevir, Pentamidine, Perampanel, Pimozide, Ponatinib, Pravastatin, Praziquantel, Progesterone, Propranolol, Quetiapine, Quinacrine, Quinine, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Salmeterol, Saquinavir, Saxagliptin, Sildenafil, Simvastatin, Sirolimus, Sorafenib, Sulfasalazine, Sunitinib, Tacrolimus, Tadalafil, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tezacaftor, Trastuzumab emtansine, Trazodone, Tretinoin, Triazolam, Udenafil, Valbenazine, Valproic Acid, Vardenafil, Verapamil, Vicriviroc, Vincristine, Zalcitabine, Zaleplon, Ziprasidone, Zolpidem
2Cytochrome P450 3A5 inducersArmodafinil, Beclomethasone dipropionate, Carbamazepine, Cyclosporine, Daunorubicin, Dexamethasone, Efavirenz, Etoposide, Midostaurin, Modafinil, Oxcarbazepine, Phenobarbital, Phenytoin, Reserpine, Rifampicin, Rifapentine, Ritonavir, Thalidomide, Troglitazone
3Cytochrome P450 3A5 inhibitorsAmiodarone, Aprepitant, Boceprevir, Chloramphenicol, Cimetidine, Ciprofloxacin, Clarithromycin, Cobicistat, Crizotinib, Delavirdine, Diltiazem, Efavirenz, Elbasvir, Enzalutamide, Erythromycin, Fluconazole, Fluticasone propionate, Fluvoxamine, Gestodene, Idelalisib, Imatinib, Indinavir, Isavuconazole, Itraconazole, Ketoconazole, Mibefradil, Mifepristone, Modafinil, Nefazodone, Nelfinavir, Nicardipine, Norfloxacin, Oxymetholone, Phenelzine, Ranitidine, Ritonavir, Rosuvastatin, Rucaparib, Saquinavir, Seproxetine, Telithromycin, Temsirolimus, Troglitazone, Troleandomycin, Verapamil, Voriconazole
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 1A1 substrate
1Cytochrome P450 1A1 substratesAcetaminophen, Amiodarone, Amodiaquine, Azelastine, Banoxantrone, Carvedilol, Chloroquine, Chlorzoxazone, Cinnarizine, Clenbuterol, Clonidine, Dacarbazine, Dapagliflozin, Dasatinib, Daunorubicin, Debrisoquin, Diclofenac, Dronabinol, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flunarizine, Flutamide, Fluvastatin, Gefitinib, Granisetron, Haloperidol, Indirubin, Lorcaserin, Melatonin, Menadione, Nicotine, Oxaliplatin, Pentamidine, Perospirone, Phenacetin, Prazosin, Progesterone, Resveratrol, Riluzole, Riociguat, Romidepsin, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Theophylline, Toremifene, Tretinoin, Troglitazone, Warfarin
2Cytochrome P450 1A1 inducersAlbendazole, Bezafibrate, Clofibrate, Clomifene, Clozapine, Dexamethasone, Dicyclomine, Ellagic Acid, Fluorescein, Itraconazole, Ketoconazole, Lansoprazole, Mebendazole, Menadione, Nicotine, Omeprazole, Phenobarbital, Picrotoxin, Primaquine, Quinine, Rabeprazole, Streptozocin, Thiabendazole, Triclocarban, Vitamin A
3Cytochrome P450 1A1 inhibitorsAmlodipine, Arsenic trioxide, Caffeine, Cannabidiol, Cholecalciferol, Clobetasol propionate, Dexamethasone, Dexmedetomidine, Ellagic Acid, Ethanol, Fluvoxamine, Gefitinib, Isoprenaline, Ketoconazole, Manidipine, Melatonin, Methoxsalen, Mibefradil, Nifedipine, Nitroprusside, Norfloxacin, Ouabain, Propofol, Propranolol, Pyridoxine, Quinidine, Quinine, Resveratrol, Sildenafil, Sulindac, Theophylline, Ticlopidine, Topiroxostat, Vitamin A
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 1A2 substrate
1Cytochrome P450 1A2 substratesAcenocoumarol, Acetaminophen, Albendazole, Almotriptan, Alosetron, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Anagrelide, Antipyrine, Apixaban, Aprepitant, Asenapine, Axitinib, Azelastine, Bendamustine, Benzyl alcohol, Betaxolol, Bortezomib, Bromazepam, Bupivacaine, Bupropion, Caffeine, Carbamazepine, Carmustine, Carvedilol, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Clenbuterol, Clevidipine, Clomipramine, Clonidine, Clopidogrel, Clozapine, Conjugated estrogens, Cyclobenzaprine, Dacarbazine, Dapagliflozin, Dasatinib, Daunorubicin, Desipramine, Deutetrabenazine, Dexfenfluramine, Diazepam, Diclofenac, Dinoprostone, Diphenhydramine, Domperidone, Doxepin, Duloxetine, Eltrombopag, Enasidenib, Ergotamine, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Estrone sulfate, Ethanol, Etoposide, Etoricoxib, Flunarizine, Flunitrazepam, Fluorouracil, Fluoxetine, Flutamide, Fluvoxamine, Frovatriptan, Genistein, Grepafloxacin, Guanabenz, Haloperidol, Hesperetin, Hexobarbital, Icotinib, Iloperidone, Imatinib, Imipramine, Imiquimod, Ixazomib, Leflunomide, Levobupivacaine, Lidocaine, Lofexidine, Lomefloxacin, Lorcaserin, Lumiracoxib, Malathion, Maprotiline, Melatonin, Menadione, Mephenytoin, Methadone, Methoxyflurane, Mexiletine, Mianserin, Mirtazapine, Muraglitazar, Nabumetone, Naproxen, Nicotine, Nifedipine, Nitric Oxide, Nortriptyline, Olanzapine, Omeprazole, Ondansetron, Oxaliplatin, Oxtriphylline, Palonosetron, Pantoprazole, Pazopanib, Pentamidine, Pentoxifylline, Perphenazine, Phenacetin, Pimozide, Pipotiazine, Pomalidomide, Praziquantel, Primaquine, Progesterone, Proguanil, Promazine, Propafenone, Propofol, Propranolol, Pyrazinamide, Quinine, Ramelteon, Ranitidine, Rasagiline, Resveratrol, Rifabutin, Riluzole, Ritonavir, Rizatriptan, Rofecoxib, Ropinirole, Ropivacaine, Rotigotine, Rucaparib, Selegiline, Sertraline, Stiripentol, Tacrine, Telithromycin, Temafloxacin, Terbinafine, Thalidomide, Theobromine, Theophylline, Thiabendazole, Thioridazine, Thiothixene, Tizanidine, Tolperisone, Toremifene, Triamterene, Trifluoperazine, Ulipristal, Vadimezan, Verapamil, Voxilaprevir, Warfarin, Zileuton, Ziprasidone, Zolmitriptan, Zolpidem, Zotepine
2Cytochrome P450 1A2 inhibitorsAbiraterone, Acyclovir, Agomelatine, Albendazole, Alitretinoin, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Anastrozole, Apomorphine, Artenimol, Atazanavir, Atropine, Azithromycin, Bortezomib, Bromocriptine, Buprenorphine, Caffeine, Carbamazepine, Carbimazole, Cimetidine, Cimicifuga racemosa, Ciprofloxacin, Citalopram, Clarithromycin, Clobetasol propionate, Clomifene, Clotrimazole, Clozapine, Conjugated estrogens, Crisaborole, Curcumin, Delavirdine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Diacerein, Diazepam, Diclofenac, Disulfiram, Dopamine, Dosulepin, Edetic Acid, Efavirenz, Eltrombopag, Enasidenib, Enoxacin, Entacapone, Epinephrine, Erythromycin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Etoricoxib, Fluconazole, Fluoxetine, Fluphenazine, Flutamide, Fluvastatin, Fluvoxamine, Gemfibrozil, Genistein, Glecaprevir, Glycerol Phenylbutyrate, Imipramine, Interferon Alfa-2b, Recombinant, Interferon gamma-1b, Irbesartan, Isoniazid, Ketoconazole, Levofloxacin, Lidocaine, Lobeglitazone, Lomefloxacin, Lopinavir, Losartan, Manidipine, Meclizine, Melatonin, Mestranol, Methimazole, Methotrimeprazine, Methoxsalen, Mexiletine, Mibefradil, Miconazole, Midostaurin, Mifepristone, Mirtazapine, Moclobemide, Modafinil, Nefazodone, Nelfinavir, Niclosamide, Nifedipine, Nilvadipine, Nisoldipine, Nitroprusside, Norepinephrine, Norfloxacin, Obeticholic acid, Ofloxacin, Olanzapine, Omeprazole, Ondansetron, Orphenadrine, Oxymetholone, Paroxetine, Pefloxacin, Peginterferon alfa-2a, Peginterferon alfa-2b, Pentoxifylline, Peppermint oil, Perphenazine, Phentermine, Phenylbutyric acid, Phenylpropanolamine, Pibrentasvir, Primaquine, Propafenone, Propofol, Propranolol, Quinidine, Quinine, Ranitidine, Resveratrol, Rhein, Rofecoxib, Ropinirole, Rosiglitazone, Rotigotine, Roxithromycin, Rucaparib, Selegiline, Sertraline, Simeprevir, Sorafenib, Sulconazole, Sulindac, Synthetic Conjugated Estrogens, A, Tegaserod, Temafloxacin, Tenofovir disoproxil, Theophylline, Thiabendazole, Thioridazine, Ticlopidine, Tioconazole, Tocainide, Topiroxostat, Tranylcypromine, Triamterene, Valaciclovir, Valproic Acid, Vemurafenib, Verapamil, Zafirlukast, Zileuton, Zucapsaicin
3Cytochrome P450 1A2 inducersAlbendazole, Aminoglutethimide, Armodafinil, Belinostat, beta-Naphthoflavone, Capsaicin, Carbamazepine, Danthron, Griseofulvin, Insulin Aspart, Insulin Beef, Insulin Detemir, Insulin Glargine, Insulin Glulisine, Insulin Human, Insulin Lispro, Insulin Pork, Lansoprazole, Menadione, Midostaurin, Modafinil, Nafcillin, Nicotine, Omeprazole, Osimertinib, Pantoprazole, Phenobarbital, Phenylephrine, Pitolisant, Primaquine, Primidone, Quinine, Rabeprazole, Resveratrol, Rifampicin, Rilpivirine, Ritonavir, Rucaparib, Secobarbital, Streptozocin
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 1B1 substrate
1Cytochrome P450 1B1 substratesAmodiaquine, Caffeine, Dasatinib, Docetaxel, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flutamide, Melatonin, Oxaliplatin, Procarbazine, Progesterone, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline
2Cytochrome P450 1B1 inhibitorsArsenic trioxide, Daunorubicin, Docetaxel, Doxorubicin, Flutamide, Ketoconazole, Melatonin, Mitoxantrone, Paclitaxel, Propofol, Resveratrol
3Cytochrome P450 1B1 inducersBiotin, Clozapine, Dexamethasone, Docetaxel, Lansoprazole, Omeprazole, Phenobarbital, Primaquine, Triclocarban
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 1B1 inhibitor
1Cytochrome P450 1B1 substratesAmodiaquine, Caffeine, Dasatinib, Docetaxel, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flutamide, Melatonin, Oxaliplatin, Procarbazine, Progesterone, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline
2Cytochrome P450 1B1 inhibitorsArsenic trioxide, Daunorubicin, Docetaxel, Doxorubicin, Flutamide, Ketoconazole, Melatonin, Mitoxantrone, Paclitaxel, Propofol, Resveratrol
3Cytochrome P450 1B1 inducersBiotin, Clozapine, Dexamethasone, Docetaxel, Lansoprazole, Omeprazole, Phenobarbital, Primaquine, Triclocarban
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2C19 substrate
1Cytochrome P450 2C19 substratesAcenocoumarol, Adinazolam, Almotriptan, Ambrisentan, Aminophenazone, Amiodarone, Amitriptyline, Amoxicillin, Antipyrine, Apixaban, Aprepitant, Arformoterol, Artemether, Asunaprevir, Atomoxetine, Axitinib, Azelastine, Benzatropine, Bioallethrin, Bortezomib, Brivaracetam, Bromazepam, Brompheniramine, Bupivacaine, Cannabidiol, Carbinoxamine, Carisoprodol, Chloramphenicol, Chlorpropamide, Cilostazol, Cisapride, Citalopram, Clarithromycin, Clobazam, clomethiazole, Clomipramine, Clopidogrel, Clotiazepam, Clozapine, Cyclophosphamide, Dapsone, Desipramine, Dexlansoprazole, Dextromethorphan, Diazepam, Diclofenac, Diltiazem, Diphenhydramine, Dopamine, Doxazosin, Doxepin, Dronabinol, Eletriptan, Enasidenib, Enfuvirtide, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Etizolam, Etravirine, Famotidine, Flunitrazepam, Fluoxetine, Flutamide, Formoterol, Fosphenytoin, Gliclazide, Glucosamine, Glyburide, Guanfacine, Haloperidol, Hexobarbital, Ibuprofen, Ifosfamide, Imatinib, Imipramine, Indomethacin, Ixazomib, Ketobemidone, Labetalol, Lansoprazole, Lapatinib, Levomilnacipran, Lofexidine, Lorcaserin, Lumiracoxib, Macitentan, Medical Cannabis, Melatonin, Mephenytoin, Meprobamate, Methadone, Methsuximide, Methylphenobarbital, Metoprolol, Moclobemide, Nabiximols, Nelfinavir, Nicotine, Nilutamide, Nortriptyline, Omeprazole, Ospemifene, Oxiconazole, Pantoprazole, Pentamidine, Pentobarbital, Perphenazine, Pethidine, Phenacetin, Phenobarbital, Phenytoin, Piperaquine, Pipotiazine, Podofilox, Prasugrel, Praziquantel, Primidone, Progesterone, Proguanil, Promazine, Propofol, Propranolol, Quazepam, Quetiapine, Quinine, Rabeprazole, Ramelteon, Ranitidine, Romidepsin, Rosuvastatin, Rupatadine, Selegiline, Seratrodast, Sertraline, Sildenafil, Tapentadol, Temazepam, Teniposide, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Thioridazine, Ticlopidine, Timolol, Tipranavir, Tofacitinib, Tolbutamide, Tolterodine, Trabectedin, Trimethadione, Trimipramine, Troglitazone, Valproic Acid, Venlafaxine, Verapamil, Voriconazole, Vortioxetine, Warfarin, Zidovudine, Zolpidem
2Cytochrome P450 2C19 inhibitorsAbiraterone, Aminophenazone, Amitriptyline, Amprenavir, Antipyrine, Aprepitant, Armodafinil, Artenimol, Atorvastatin, Azelastine, Benzbromarone, Bicalutamide, Bifonazole, Bortezomib, Buprenorphine, Carbamazepine, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Citalopram, Clarithromycin, Clevidipine, Clotrimazole, Clozapine, Cyclosporine, Delavirdine, Desipramine, Desloratadine, Dexfenfluramine, Dexlansoprazole, Diazepam, Dimethyl sulfoxide, Dosulepin, Efavirenz, Enasidenib, Eslicarbazepine acetate, Esomeprazole, Ethanol, Ethotoin, Etoricoxib, Etravirine, Felbamate, Fluconazole, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Gliclazide, Idelalisib, Imipramine, Indinavir, Indomethacin, Isavuconazole, Isoniazid, Ketoconazole, Lansoprazole, Lobeglitazone, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Manidipine, Memantine, Mephenytoin, Methazolamide, Methimazole, Methsuximide, Methylphenobarbital, Miconazole, Midostaurin, Moclobemide, Modafinil, Naloxegol, Nelfinavir, Nicardipine, Nilutamide, Nilvadipine, Olanzapine, Omeprazole, Opicapone, Oxcarbazepine, Oxymetholone, Pantoprazole, Pegvisomant, Phenelzine, Phensuximide, Pimozide, Pioglitazone, Piperaquine, Probenecid, Progesterone, Quinine, Rabeprazole, Regorafenib, Rilpivirine, Ritonavir, Rosiglitazone, Rucaparib, Saquinavir, Seratrodast, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulfanilamide, Telmisartan, Thalidomide, Ticlopidine, Tioconazole, Tipranavir, Tolbutamide, Topiramate, Topiroxostat, Torasemide, Tranylcypromine, Troglitazone, Troleandomycin, Valdecoxib, Valproic Acid, Vismodegib, Voriconazole, Warfarin, Zafirlukast, Zonisamide, Zucapsaicin
3Cytochrome P450 2C19 inducersAcetylsalicylic acid, Aminoglutethimide, Apalutamide, Artemether, Carbamazepine, Dexamethasone, Enzalutamide, Hydroxyprogesterone caproate, Letermovir, Lopinavir, Loratadine, Lumacaftor, Midostaurin, Modafinil, Norethisterone, Phenobarbital, Prednisone, Primidone, Rifampicin, Ritonavir
Interacting GroupInteracting Drugs
Tamoxifen is a Dimethylaniline monooxygenase [N-oxide-forming] 1 substrate
1Dimethylaniline monooxygenase [N-oxide-forming] 1 substratesCevimeline, Cimetidine, Lorcaserin, Propiverine, Vandetanib, Voriconazole
Interacting GroupInteracting Drugs
Tamoxifen is a Dimethylaniline monooxygenase [N-oxide-forming] 3 substrate
1Dimethylaniline monooxygenase [N-oxide-forming] 3 substratesAlmotriptan, Cimetidine, Clozapine, Dapsone, Dasatinib, Neratinib, Olanzapine, Propiverine, Vandetanib, Voriconazole
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 3A7 substrate
1Cytochrome P450 3A7 substratesAlfentanil, Alprazolam, Aminophenazone, Amlodipine, Aprepitant, Aripiprazole, Astemizole, Atorvastatin, Buprenorphine, Buspirone, Caffeine, Carbamazepine, Cerivastatin, Chlorphenamine, Cilostazol, Cisapride, Clarithromycin, Cobicistat, Cocaine, Codeine, Copanlisib, Cyclophosphamide, Cyclosporine, Daclatasvir, Dapsone, Dexamethasone, Dextromethorphan, Diazepam, Diltiazem, Docetaxel, Domperidone, Elbasvir, Eplerenone, Erythromycin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethosuximide, Ethylmorphine, Felodipine, Fentanyl, Finasteride, Fluticasone propionate, Haloperidol, Hydrocortisone, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Imipramine, Indinavir, Irinotecan, Lercanidipine, Levomethadyl Acetate, Lidocaine, Lovastatin, Methadone, Midazolam, Nateglinide, Nelfinavir, Nifedipine, Nisoldipine, Nitrendipine, Norethisterone, Ondansetron, Oxazepam, Oxycodone, Paclitaxel, Pimozide, Prasterone, Prasterone sulfate, Praziquantel, Progesterone, Propranolol, Quetiapine, Quinidine, Quinine, Risperidone, Ritonavir, Salmeterol, Saquinavir, Sildenafil, Simvastatin, Sirolimus, Sorafenib, Sunitinib, Tacrolimus, Telithromycin, Temsirolimus, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Trazodone, Tretinoin, Triazolam, Verapamil, Vincristine, Zalcitabine, Zaleplon, Ziprasidone, Zolpidem
2Cytochrome P450 3A7 inhibitorsAmiodarone, Aprepitant, Chloramphenicol, Cimetidine, Ciprofloxacin, Cobicistat, Delavirdine, Diltiazem, Efavirenz, Elbasvir, Erythromycin, Fluconazole, Fluvoxamine, Gestodene, Idelalisib, Imatinib, Indinavir, Itraconazole, Ketoconazole, Mibefradil, Midazolam, Mifepristone, Nelfinavir, Norfloxacin, Oxymetholone, Phenelzine, Prasterone, Progesterone, Ritonavir, Rucaparib, Saquinavir, Seproxetine, Telithromycin, Troglitazone, Troleandomycin, Verapamil, Voriconazole
3Cytochrome P450 3A7 inducersClotrimazole, Cyclosporine, Dexamethasone, Dextropropoxyphene, Efavirenz, Midostaurin, Phenobarbital, Phenytoin, Rifampicin, Rifapentine, Ritonavir, Troglitazone
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 19A1 inhibitor
1Cytochrome P450 19A1 inhibitorsAminoglutethimide, Anastrozole, Bifonazole, Carbimazole, Clomifene, Clotrimazole, Cyproterone acetate, Danazol, Drostanolone, Econazole, Etomidate, Etretinate, Exemestane, Ketoconazole, Letrozole, Levonorgestrel, Mefloquine, Melatonin, Miconazole, Naringenin, Nicotine, Norgestrel, Paclitaxel, Raloxifene, substance P, Terbinafine, Testolactone, Tioconazole, Trastuzumab, Troglitazone
2Cytochrome P450 19A1 antagonistsLetrozole
3Cytochrome P450 19A1 substratesBetamethasone, Edetic Acid, Endostatin, Letrozole, Levomethadyl Acetate, Methadone, Nandrolone phenpropionate, Stanolone, Stanolone acetate, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate
4Cytochrome P450 19A1 inducersBetamethasone, Buserelin, Chlorotrianisene, Chlorphenesin, Dexamethasone, Diethylstilbestrol, Dinoprostone, Methyltestosterone, Nandrolone decanoate, Prasterone sulfate, Sulfathiazole
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2A6 substrate
1Cytochrome P450 2A6 substratesAcetaminophen, Antipyrine, Arformoterol, Asunaprevir, Bupropion, Chlorzoxazone, Cinnarizine, Cisapride, clomethiazole, Clozapine, Cyclophosphamide, Dapagliflozin, Dronabinol, Flunarizine, Flunitrazepam, Fluorouracil, Flurazepam, Formoterol, Halothane, Ifosfamide, Letrozole, Lidocaine, Lorcaserin, Methoxsalen, Methoxyflurane, Montelukast, Nevirapine, Nicotine, Nifedipine, Phenacetin, Pilocarpine, Progesterone, Propofol, Rifampicin, Selegiline, Sevoflurane, Tegafur, Tegafur-uracil, Tretinoin, Valproic Acid, Vortioxetine, Zidovudine
2Cytochrome P450 2A6 inhibitorsAmiodarone, Amlodipine, Amphetamine, Azelastine, Azithromycin, Buprenorphine, Clofibrate, Clomifene, Clotrimazole, Desipramine, Dexfenfluramine, Diethylstilbestrol, Ezogabine, Fomepizole, Isoniazid, Ketoconazole, Letrozole, Memantine, Menadione, Methimazole, Methoxsalen, Metyrapone, Miconazole, Nicotine, Nilvadipine, Norfloxacin, Phenobarbital, Pilocarpine, Prednisolone, Rifampicin, Rosiglitazone, Seratrodast, Sulfaphenazole, Tranylcypromine, Troleandomycin
3Cytochrome P450 2A6 inducersAmobarbital, Dexamethasone, Eletriptan, Pentobarbital, Phenobarbital, Rifampicin, Valproic Acid
Interacting GroupInteracting Drugs
Tamoxifen is a Cytochrome P450 2E1 substrate
1Cytochrome P450 2E1 substratesAcetaminophen, Almotriptan, Aminophylline, Amitriptyline, Aniline, Antipyrine, Benzyl alcohol, Brompheniramine, Bupropion, Caffeine, Capsaicin, Carbinoxamine, Carvedilol, Chlorzoxazone, Citalopram, Clevidipine, Dacarbazine, Dalfampridine, Dapsone, Dexmedetomidine, Dextromethorphan, Enflurane, Enfuvirtide, Estrone, Ethanol, Ethanolamine Oleate, Ethosuximide, Etoposide, Felbamate, Fingolimod, Fluvoxamine, Folic Acid, Glucosamine, Halothane, Iloperidone, Isoflurane, Isoniazid, Menadione, Meprobamate, Methoxyflurane, Mexiletine, Mitoxantrone, N-Methyl-N-(Methylbenzyl)Formamide, Nicardipine, Nicotine, Nilvadipine, Ondansetron, Oxaliplatin, Paramethadione, Phenacetin, Phenobarbital, Pilocarpine, Proguanil, Propofol, Quinidine, Quinine, Sevoflurane, Sildenafil, Sulfadiazine, Thalidomide, Theobromine, Theophylline, Tirapazamine, Trabectedin, Trimethadione, Zopiclone
2Cytochrome P450 2E1 inhibitorsAdemetionine, Aldesleukin, Alosetron, Amitriptyline, Azelastine, Bifonazole, Bromazepam, Chlorpromazine, Chlorzoxazone, Cimetidine, Clomifene, Clonazepam, Clotrimazole, Clozapine, Desipramine, Dexfenfluramine, Diacerein, Diazepam, Diclofenac, Diethylstilbestrol, Disulfiram, Econazole, Ellagic Acid, Ethanol, Etoricoxib, Flunitrazepam, Fluphenazine, Flurazepam, Fomepizole, Imipramine, Indisulam, Isoniazid, Isosorbide Dinitrate, Itraconazole, Methazolamide, Methimazole, Methotrimeprazine, Metyrapone, Miconazole, Midazolam, Midostaurin, Nabilone, Nicotinamide, Nicotine, Nifedipine, Nitrazepam, Nortriptyline, Pimozide, Propofol, Rhein, Ritonavir, Rufinamide, Selegiline, Sildenafil, Sulfanilamide, Tegaserod, Thiopental, Thioridazine, Ticlopidine, Tioconazole, Tranylcypromine, Ursodeoxycholic acid, Vayarin, Zafirlukast, Zucapsaicin
3Cytochrome P450 2E1 inducersClofibrate, Colchicine, Delafloxacin, Dexamethasone, Ethanol, Glycerin, Isoniazid, Nicotine, Phenelzine, Phenobarbital, Piperaquine, Rifampicin, Streptozocin, Ursodeoxycholic acid
Interacting GroupInteracting Drugs
Tamoxifen is a UDP-glucuronosyltransferase 1-10 substrate
1UDP-glucuronosyltransferase 1-10 substratesAcetaminophen, Etodolac, Losartan, Mycophenolate mofetil, Troglitazone, Valproic Acid
Interacting GroupInteracting Drugs
Tamoxifen is a Sulfotransferase 1A1 substrate
1Sulfotransferase 1A1 substratesAcetaminophen, Polyethylene glycol 400, Tibolone
Interacting GroupInteracting Drugs
Tamoxifen is a Multidrug resistance protein 1 substrate
1Multidrug resistance protein 1 inducersAldosterone, Amiodarone, Amprenavir, Apalutamide, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Cyclosporine, Daunorubicin, Dexamethasone, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Indinavir, Levothyroxine, Liothyronine, Liotrix, Lumacaftor, Midazolam, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Norethisterone, Phenobarbital, Platelet Activating Factor, Progesterone, Reserpine, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tesmilifene, Trazodone, Trimethoprim, Verapamil, Vinblastine, Vincristine
2Multidrug resistance protein 1 substratesAbemaciclib, Acebutolol, Acetaminophen, Acetylsalicylic acid, Afatinib, Aldosterone, Alitretinoin, Ambrisentan, Amitriptyline, Amprenavir, Apixaban, Arsenic trioxide, Asunaprevir, Atazanavir, Atenolol, Avatrombopag, Axitinib, Baricitinib, Belinostat, Betamethasone, Bosutinib, Bromocriptine, Cabazitaxel, Caffeine, Camptothecin, Canagliflozin, Carfilzomib, Ceritinib, Cerivastatin, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clobazam, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Dactinomycin, Dapagliflozin, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquin, Dexamethasone, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxorubicin, Edoxaban, Elbasvir, Eletriptan, Epinastine, Erlotinib, Ertugliflozin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinyl Estradiol, Etoposide, Ezetimibe, Fesoterodine, Fexofenadine, Fidaxomicin, Fluciclovine (18F), Fluticasone furoate, Gefitinib, Gemcitabine, Glecaprevir, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ketazolam, Ketoconazole, Lamivudine, Lamotrigine, Lansoprazole, Lenalidomide, Lenvatinib, Letermovir, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Losartan, Mannitol, Methotrexate, Methylprednisolone, Metoprolol, Midazolam, Mirabegron, Mitoxantrone, Morphine, Moxidectin, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nizatidine, Odanacatib, Olanzapine, Ombitasvir, Osimertinib, Paclitaxel, Panobinostat, Paritaprevir, Pazopanib, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Pomalidomide, Ponatinib, Pravastatin, Prazosin, Prednisolone, Prednisone, Progesterone, Propranolol, Quetiapine, Quinidine, Quinine, Ranitidine, Reserpine, Rifampicin, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Taurocholic Acid, Technetium Tc-99m sestamibi, Telaprevir, Temsirolimus, Testosterone propionate, Ticagrelor, Timolol, Tolvaptan, Topotecan, Toremifene, Trastuzumab emtansine, Trimipramine, Ubidecarenone, Umeclidinium, Vecuronium, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vinorelbine, Vismodegib, Voxilaprevir, Zidovudine
3Multidrug resistance protein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Albendazole, Alectinib, Alfentanil, Amiodarone, Amitriptyline, Amlodipine, Amsacrine, Astemizole, Atazanavir, Atorvastatin, Azelastine, Azithromycin, Benzocaine, Bepridil, Boceprevir, Bosutinib, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carvedilol, Caspofungin, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colchicine, Colforsin, Concanamycin A, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dactinomycin, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexniguldipine, Dexverapamil, Diclofenac, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Doxazosin, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Emopamil, Enalapril, Enasidenib, Enzalutamide, Ergonovine, Ergotamine, Erythromycin, Estramustine, Etoposide, Felodipine, Fentanyl, Fexofenadine, Fidaxomicin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Gefitinib, Genistein, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Itraconazole, Ivacaftor, Ivermectin, Ketoconazole, Lansoprazole, Lapatinib, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Mefloquine, Megestrol acetate, Methadone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mitoxantrone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nisoldipine, Nitrendipine, Omeprazole, ONT-093, Paclitaxel, Pantoprazole, Paroxetine, Pibrentasvir, Pimozide, Ponatinib, Posaconazole, Prazosin, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Saquinavir, Scopolamine, Selegiline, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Taurocholic Acid, Telaprevir, Telmisartan, Temsirolimus, Terazosin, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Ticagrelor, Tolvaptan, Trifluoperazine, Triflupromazine, Trimethoprim, Troleandomycin, Velpatasvir, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine
4Multidrug resistance protein 1 transportersalpha-Tocopherol acetate, Betrixaban, Ledipasvir, Tocopherol
5Multidrug resistance protein 1 bindersTechnetium Tc-99m tetrofosmin
6Multidrug resistance protein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Tamoxifen is a Multidrug resistance protein 1 inhibitor
1Multidrug resistance protein 1 inducersAldosterone, Amiodarone, Amprenavir, Apalutamide, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Cyclosporine, Daunorubicin, Dexamethasone, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Indinavir, Levothyroxine, Liothyronine, Liotrix, Lumacaftor, Midazolam, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Norethisterone, Phenobarbital, Platelet Activating Factor, Progesterone, Reserpine, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tesmilifene, Trazodone, Trimethoprim, Verapamil, Vinblastine, Vincristine
2Multidrug resistance protein 1 substratesAbemaciclib, Acebutolol, Acetaminophen, Acetylsalicylic acid, Afatinib, Aldosterone, Alitretinoin, Ambrisentan, Amitriptyline, Amprenavir, Apixaban, Arsenic trioxide, Asunaprevir, Atazanavir, Atenolol, Avatrombopag, Axitinib, Baricitinib, Belinostat, Betamethasone, Bosutinib, Bromocriptine, Cabazitaxel, Caffeine, Camptothecin, Canagliflozin, Carfilzomib, Ceritinib, Cerivastatin, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clobazam, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Dactinomycin, Dapagliflozin, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquin, Dexamethasone, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxorubicin, Edoxaban, Elbasvir, Eletriptan, Epinastine, Erlotinib, Ertugliflozin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinyl Estradiol, Etoposide, Ezetimibe, Fesoterodine, Fexofenadine, Fidaxomicin, Fluciclovine (18F), Fluticasone furoate, Gefitinib, Gemcitabine, Glecaprevir, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ketazolam, Ketoconazole, Lamivudine, Lamotrigine, Lansoprazole, Lenalidomide, Lenvatinib, Letermovir, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Losartan, Mannitol, Methotrexate, Methylprednisolone, Metoprolol, Midazolam, Mirabegron, Mitoxantrone, Morphine, Moxidectin, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nizatidine, Odanacatib, Olanzapine, Ombitasvir, Osimertinib, Paclitaxel, Panobinostat, Paritaprevir, Pazopanib, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Pomalidomide, Ponatinib, Pravastatin, Prazosin, Prednisolone, Prednisone, Progesterone, Propranolol, Quetiapine, Quinidine, Quinine, Ranitidine, Reserpine, Rifampicin, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Taurocholic Acid, Technetium Tc-99m sestamibi, Telaprevir, Temsirolimus, Testosterone propionate, Ticagrelor, Timolol, Tolvaptan, Topotecan, Toremifene, Trastuzumab emtansine, Trimipramine, Ubidecarenone, Umeclidinium, Vecuronium, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vinorelbine, Vismodegib, Voxilaprevir, Zidovudine
3Multidrug resistance protein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Albendazole, Alectinib, Alfentanil, Amiodarone, Amitriptyline, Amlodipine, Amsacrine, Astemizole, Atazanavir, Atorvastatin, Azelastine, Azithromycin, Benzocaine, Bepridil, Boceprevir, Bosutinib, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carvedilol, Caspofungin, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colchicine, Colforsin, Concanamycin A, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dactinomycin, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexniguldipine, Dexverapamil, Diclofenac, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Doxazosin, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Emopamil, Enalapril, Enasidenib, Enzalutamide, Ergonovine, Ergotamine, Erythromycin, Estramustine, Etoposide, Felodipine, Fentanyl, Fexofenadine, Fidaxomicin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Gefitinib, Genistein, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Itraconazole, Ivacaftor, Ivermectin, Ketoconazole, Lansoprazole, Lapatinib, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Mefloquine, Megestrol acetate, Methadone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mitoxantrone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nisoldipine, Nitrendipine, Omeprazole, ONT-093, Paclitaxel, Pantoprazole, Paroxetine, Pibrentasvir, Pimozide, Ponatinib, Posaconazole, Prazosin, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Saquinavir, Scopolamine, Selegiline, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Taurocholic Acid, Telaprevir, Telmisartan, Temsirolimus, Terazosin, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Ticagrelor, Tolvaptan, Trifluoperazine, Triflupromazine, Trimethoprim, Troleandomycin, Velpatasvir, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine
4Multidrug resistance protein 1 transportersalpha-Tocopherol acetate, Betrixaban, Ledipasvir, Tocopherol
5Multidrug resistance protein 1 bindersTechnetium Tc-99m tetrofosmin
6Multidrug resistance protein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Tamoxifen is a Multidrug resistance protein 1 inducer
1Multidrug resistance protein 1 inducersAldosterone, Amiodarone, Amprenavir, Apalutamide, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Cyclosporine, Daunorubicin, Dexamethasone, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Indinavir, Levothyroxine, Liothyronine, Liotrix, Lumacaftor, Midazolam, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Norethisterone, Phenobarbital, Platelet Activating Factor, Progesterone, Reserpine, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tesmilifene, Trazodone, Trimethoprim, Verapamil, Vinblastine, Vincristine
2Multidrug resistance protein 1 substratesAbemaciclib, Acebutolol, Acetaminophen, Acetylsalicylic acid, Afatinib, Aldosterone, Alitretinoin, Ambrisentan, Amitriptyline, Amprenavir, Apixaban, Arsenic trioxide, Asunaprevir, Atazanavir, Atenolol, Avatrombopag, Axitinib, Baricitinib, Belinostat, Betamethasone, Bosutinib, Bromocriptine, Cabazitaxel, Caffeine, Camptothecin, Canagliflozin, Carfilzomib, Ceritinib, Cerivastatin, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clobazam, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Dactinomycin, Dapagliflozin, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquin, Dexamethasone, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxorubicin, Edoxaban, Elbasvir, Eletriptan, Epinastine, Erlotinib, Ertugliflozin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinyl Estradiol, Etoposide, Ezetimibe, Fesoterodine, Fexofenadine, Fidaxomicin, Fluciclovine (18F), Fluticasone furoate, Gefitinib, Gemcitabine, Glecaprevir, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ketazolam, Ketoconazole, Lamivudine, Lamotrigine, Lansoprazole, Lenalidomide, Lenvatinib, Letermovir, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Losartan, Mannitol, Methotrexate, Methylprednisolone, Metoprolol, Midazolam, Mirabegron, Mitoxantrone, Morphine, Moxidectin, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nizatidine, Odanacatib, Olanzapine, Ombitasvir, Osimertinib, Paclitaxel, Panobinostat, Paritaprevir, Pazopanib, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Pomalidomide, Ponatinib, Pravastatin, Prazosin, Prednisolone, Prednisone, Progesterone, Propranolol, Quetiapine, Quinidine, Quinine, Ranitidine, Reserpine, Rifampicin, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Taurocholic Acid, Technetium Tc-99m sestamibi, Telaprevir, Temsirolimus, Testosterone propionate, Ticagrelor, Timolol, Tolvaptan, Topotecan, Toremifene, Trastuzumab emtansine, Trimipramine, Ubidecarenone, Umeclidinium, Vecuronium, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vinorelbine, Vismodegib, Voxilaprevir, Zidovudine
3Multidrug resistance protein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Albendazole, Alectinib, Alfentanil, Amiodarone, Amitriptyline, Amlodipine, Amsacrine, Astemizole, Atazanavir, Atorvastatin, Azelastine, Azithromycin, Benzocaine, Bepridil, Boceprevir, Bosutinib, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carvedilol, Caspofungin, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colchicine, Colforsin, Concanamycin A, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dactinomycin, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexniguldipine, Dexverapamil, Diclofenac, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Doxazosin, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Emopamil, Enalapril, Enasidenib, Enzalutamide, Ergonovine, Ergotamine, Erythromycin, Estramustine, Etoposide, Felodipine, Fentanyl, Fexofenadine, Fidaxomicin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Gefitinib, Genistein, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Itraconazole, Ivacaftor, Ivermectin, Ketoconazole, Lansoprazole, Lapatinib, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Mefloquine, Megestrol acetate, Methadone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mitoxantrone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nisoldipine, Nitrendipine, Omeprazole, ONT-093, Paclitaxel, Pantoprazole, Paroxetine, Pibrentasvir, Pimozide, Ponatinib, Posaconazole, Prazosin, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Saquinavir, Scopolamine, Selegiline, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Taurocholic Acid, Telaprevir, Telmisartan, Temsirolimus, Terazosin, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Ticagrelor, Tolvaptan, Trifluoperazine, Triflupromazine, Trimethoprim, Troleandomycin, Velpatasvir, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine
4Multidrug resistance protein 1 transportersalpha-Tocopherol acetate, Betrixaban, Ledipasvir, Tocopherol
5Multidrug resistance protein 1 bindersTechnetium Tc-99m tetrofosmin
6Multidrug resistance protein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Tamoxifen is a ATP-binding cassette sub-family G member 2 substrate
1ATP-binding cassette sub-family G member 2 substratesAbemaciclib, Afatinib, Alvocidib, Apixaban, Baricitinib, Brigatinib, Camptothecin, Carboplatin, Cerivastatin, Cisplatin, Cladribine, Clofarabine, Conjugated estrogens, Copanlisib, Dabrafenib, Dactinomycin, Dasatinib, Daunorubicin, Delafloxacin, Docetaxel, Dolutegravir, Doxorubicin, Enasidenib, Ertugliflozin, Etoposide, Ezetimibe, Fluorouracil, Folic Acid, Gefitinib, Glecaprevir, Glyburide, Idelalisib, Imatinib, Irinotecan, Ivermectin, Lamivudine, Leflunomide, Lenvatinib, Methotrexate, Mitoxantrone, Moxidectin, Mycophenolate mofetil, Nilotinib, Nitrofurantoin, Ombitasvir, Osimertinib, Oxaliplatin, Paclitaxel, Pazopanib, Pibrentasvir, Pitavastatin, Ponatinib, Pravastatin, Prazosin, Riluzole, Riociguat, Rosuvastatin, Rucaparib, Simeprevir, Sofosbuvir, Sorafenib, Sulfasalazine, Sumatriptan, Teniposide, Teriflunomide, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Topotecan, Velpatasvir, Vemurafenib, Venetoclax, Vincristine, Voxilaprevir, Zidovudine
2ATP-binding cassette sub-family G member 2 inhibitorsAbemaciclib, Afatinib, Alectinib, Avatrombopag, Baricitinib, Brigatinib, Buprenorphine, Cabazitaxel, Cannabidiol, Cobicistat, Cyclosporine, Dabrafenib, Daclatasvir, Daidzin, Dasabuvir, Dasatinib, Dexamethasone, Diethylstilbestrol, Dronabinol, Elacridar, Enasidenib, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Fostamatinib, Gefitinib, Genistein, Glecaprevir, Hesperetin, Hydrocortisone, Imatinib, Isavuconazole, Lansoprazole, Letermovir, Medical Cannabis, Nabiximols, Naringenin, Nelfinavir, Nilotinib, Novobiocin, Omeprazole, Pantoprazole, Paritaprevir, Pibrentasvir, Ponatinib, Pravastatin, Quercetin, Rabeprazole, Regorafenib, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Safinamide, Saquinavir, Simeprevir, Sorafenib, Sulfasalazine, Sunitinib, Taurocholic Acid, Telmisartan, Topiroxostat, Vandetanib, Velpatasvir, Verapamil, Vismodegib, Voxilaprevir
3ATP-binding cassette sub-family G member 2 inducersApalutamide, Cholesterol, Venlafaxine
4ATP-binding cassette sub-family G member 2 antagonistsZafirlukast
5ATP-binding cassette sub-family G member 2 weak inhibitorsCobimetinib
6ATP-binding cassette sub-family G member 2 transportersLedipasvir
Interacting GroupInteracting Drugs
Tamoxifen is a Canalicular multispecific organic anion transporter 1 substrate
1Canalicular multispecific organic anion transporter 1 inhibitors(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I), 5-methyltetrahydrofolic acid, Aminohippuric acid, Cyclosporine, Daunorubicin, Etoposide, Furosemide, Fusidic Acid, Glutathione, Glyburide, Grepafloxacin, Indomethacin, Ivermectin, Letermovir, Lomefloxacin, Methotrexate, Ofloxacin, Pranlukast, Pravastatin, Probenecid, Quinidine, Reserpine, Simeprevir, Sorafenib, Sparfloxacin, Sulfinpyrazone, Sunitinib, Telmisartan, Tetrahydrofolic acid, Verapamil, Vinblastine, Vincristine
2Canalicular multispecific organic anion transporter 1 substratesAminohippuric acid, Atorvastatin, Avibactam, Canagliflozin, Carbamazepine, Carboplatin, Cerivastatin, Conjugated estrogens, Docetaxel, Doxorubicin, Eluxadoline, Etoposide, Ezetimibe, Fluvastatin, Gadoxetic acid, Glutathione, Indinavir, Indomethacin, Irinotecan, Levetiracetam, Lovastatin, Methotrexate, Mycophenolate mofetil, Norgestimate, Olmesartan, Oxaliplatin, Paclitaxel, Phenytoin, Pitavastatin, Pravastatin, Probenecid, Ritonavir, Rosuvastatin, Saquinavir, Simeprevir, Simvastatin, Sulfasalazine, Sulfinpyrazone, Tenofovir disoproxil, Vasopressin, Vinblastine, Vincristine
3Canalicular multispecific organic anion transporter 1 inducersArsenic trioxide, Cholic Acid, Cisplatin, Clotrimazole, Dexamethasone, Eprosartan, Ethinyl Estradiol, Hyperforin, Nifedipine, Olmesartan, Phenobarbital, Quercetin, Rifampicin, Ritonavir, Spironolactone, Taurocholic Acid, Ursodeoxycholic acid, Vinblastine
4Canalicular multispecific organic anion transporter 1 transportersIndocyanine green acid form